infanim ser tablet - Nimesulide (NA) + Serratiopeptidase (NA) medicine

Adpep N Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Agron Remedies Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for short-term use in acute inflammatory conditions.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is infanim ser tablet used for?

This medicine is a combination of nimesulide and serratiopeptidase used for short-term relief of pain, inflammation, and swelling. It works by reducing prostaglandins and breaking down fibrin. It is taken orally with food, usually twice daily, and should not be used for more than 7 days without medical advice.

  • Generic Name: Nimesulide (NA) + Serratiopeptidase (NA)
  • Manufacturer: Agron Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 infanim ser tablet के बारे में (Hindi Summary)

उपयोग: यह दवा नाइमेसुलाइड और सेरेशियोपेप्टिडेज़ का संयोजन है, जिसका उपयोग दर्द, सूजन और सूजन से राहत के लिए किया जाता है। यह मुख्य रूप से सर्जरी के बाद की सूजन, चोट लगने पर सूजन, मांसपेशियों और जोड़ों के दर्द, और साइनसाइटिस में उपयोग की जाती है। यह दवा सूजन को कम करने और दर्द को शांत करने में मदद करती है। इसे भोजन के साथ लेना चाहिए। यह दवा केवल अल्पकालिक उपयोग के लिए है और इसे 7 दिनों से अधिक नहीं लेना चाहिए। बच्चों, गर्भवती महिलाओं और स्तनपान कराने वाली महिलाओं को यह दवा नहीं लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट में असुविधा, दस्त, सिरदर्द और जलन शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, यकृत की क्षति, गुर्दे की समस्या, और त्वचा पर गंभीर प्रतिक्रियाएं हो सकती हैं। यदि आपको काला मल, खून की उल्टी, पेट में तेज दर्द, आंखों या त्वचा का पीलापन, या पेशाब कम आना जैसे लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आपको पेट का अल्सर, गुर्दे या यकृत की बीमारी है, तो यह दवा न लें। अन्य दवाओं के साथ इसका सेवन करने से पहले डॉक्टर से सलाह लें। 7 दिनों से अधिक इस दवा का उपयोग न करें। गर्भवती और स्तनपान कराने वाली महिलाएं इस दवा का सेवन न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 infanim ser tablet Uses & Benefits

[{"condition":"Post-operative inflammation and edema","description":"Reduces swelling and pain after surgical procedures.","evidence":"Moderate"},{"condition":"Traumatic edema","description":"Helps resolve swelling caused by injuries.","evidence":"Moderate"},{"condition":"Acute musculoskeletal pain","description":"Provides relief from pain and inflammation in muscles and joints.","evidence":"Moderate"},{"condition":"Sinusitis","description":"Reduces inflammation and congestion in sinus cavities.","evidence":"Limited"},{"condition":"Dental pain and swelling","description":"Used for short-term relief of dental inflammation.","evidence":"Limited"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used for menstrual pain, but not a first-line option.","evidence":"Limited"}]

Primary treatment for: Inflammatory conditions with pain and edema

Also treats: Post-operative swelling, Traumatic edema, Musculoskeletal pain, Sinusitis

📋 Drug Information

Generic Name(s)Nimesulide (NA) + Serratiopeptidase (NA)
Brand Nameinfanim ser tablet
ManufacturerAgron Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to minimize stomach irritation.
2
Do not exceed the prescribed dose or duration; short-term use is recommended.
3
Avoid alcohol completely while taking this medicine to prevent gastrointestinal bleeding.
4
Inform your doctor if you have a history of ulcer, kidney, liver, or heart disease.
5
Stay well hydrated throughout the day to support kidney function.
6
Report any unusual bleeding, bruising, or yellowing of eyes immediately.
7
Do not take other pain relievers without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Post-operative swelling
This medicine is commonly prescribed for this.
Likely Use
✅
Traumatic edema
This medicine helps reduce swelling.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNimesulide is rapidly absorbed from the gastrointestinal tract after oral administration. Serratiopeptidase is absorbed intact through the intestinal mucosa, though the exact bioavailability is not well established.
DistributionNimesulide is highly protein-bound and distributes widely into body tissues, including synovial fluid. Serratiopeptidase distribution is not well characterized.
Protein BindingNimesulide is approximately 99% bound to plasma proteins. Serratiopeptidase binding is not established from the available information.
MetabolismNimesulide is extensively metabolized in the liver, primarily by CYP2C9, to several metabolites, including 4-hydroxynimesulide, which is pharmacologically active. Serratiopeptidase is metabolized by proteolytic enzymes in the body.
Half-LifeThe elimination half-life of nimesulide is approximately 1.8 to 4.7 hours. The half-life of serratiopeptidase is not established from the available information.
ExcretionNimesulide and its metabolites are excreted primarily in urine (about 70%) and feces (about 20%). Serratiopeptidase is excreted via the kidneys and bile.
BioavailabilityThe oral bioavailability of nimesulide is approximately 80-90%. The bioavailability of serratiopeptidase is not well established.
Onset of ActionNimesulide begins to relieve pain within 30-60 minutes after oral administration. Serratiopeptidase may take several hours to days to show anti-edema effects.
Peak Plasma TimeNimesulide reaches peak plasma concentration in about 1.5 to 3 hours. Serratiopeptidase peak time is not established.
Duration of ActionThe analgesic and anti-inflammatory effects of nimesulide last for about 6-8 hours. The duration of serratiopeptidase action is not well established.

How It Works

This medicine combines two active ingredients. Nimesulide selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, reducing the production of prostaglandins, which are mediators of pain, inflammation, and fever. Serratiopeptidase is a proteolytic enzyme that breaks down fibrin and other proteins involved in inflammation, thereby reducing swelling and promoting tissue repair. Together, they provide anti-inflammatory, analgesic, and anti-edema effects.

Mechanism Steps

1
COX-2 inhibition by nimesulide: Nimesulide selectively binds to and inhibits the COX-2 enzyme, reducing prostaglandin synthesis.
2
Reduced prostaglandin production: Lower prostaglandin levels decrease pain, fever, and inflammation.
3
Proteolytic action of serratiopeptidase: Serratiopeptidase breaks down fibrin and other proteins that contribute to swelling and inflammation.
4
Enhanced drainage and tissue repair: By breaking down fibrin, serratiopeptidase promotes drainage of inflammatory fluids and aids tissue repair.

💡 How to Take infanim ser tablet

Strength: Nimesulide 100 mg + Serratiopeptidase 10 mg (typical composition). Actual strength may vary; refer to the product label.

1Take the tablet orally with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the prescribed dose and duration exactly.
5Do not take more than the recommended dose.
6If you miss a dose, follow the missed dose instructions.
7Store the medicine properly and keep out of reach of children.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally twice daily, preferably after meals. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function. Do not exceed the recommended dose. This medicine is intended for short-term use only, typically not exceeding 7 days.
Pediatric DosagePediatric dosing is not established from available information. This medicine is not recommended for children below 12 years of age. Consult a pediatrician for appropriate alternatives.
Elderly DosageElderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal and renal side effects. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose reduction may be necessary. This medicine is contraindicated in severe renal impairment (eGFR <30 mL/min). Consult a nephrologist for dosing guidance.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. This medicine is contraindicated in severe hepatic impairment. Monitor liver function closely. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose of nimesulide is 200 mg. The maximum daily dose of serratiopeptidase is not well established. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of infanim ser tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Abdominal discomfort (Common (5-10%))
Take with food or milk. If severe, consult doctor.
Heartburn (Common (5-10%))
Avoid spicy foods. Consult doctor if it persists.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if diarrhea is severe or persistent.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Hepatotoxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue immediately.
Renal impairment (Rare (<0.1%))
Report decreased urine output or swelling. Seek medical attention.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Seek immediate medical attention if you develop rash, blisters, or peeling skin.
Cardiovascular events (Rare (<0.1%))
Report chest pain, shortness of breath, or swelling of legs immediately.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bleeding or bruising, sore throat, or fever.
Pancreatitis
Seek immediate medical attention for severe abdominal pain radiating to back.
Allergic reactions
Seek immediate medical attention if you experience rash, itching, swelling, or difficulty breathing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
ACE inhibitors Major
Diuretics Major
Lithium Moderate
Methotrexate Moderate
Corticosteroids Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs
  • ACE inhibitors and ARBs
  • Diuretics

⚡ Moderate Interactions

  • Lithium
  • Methotrexate
  • Corticosteroids

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it increases the risk of gastrointestinal bleeding and may worsen liver toxicity.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to nimesulide, serratiopeptidase, or any component of the formulation.","Active peptic ulcer or history of recurrent peptic ulcer.","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Use with caution in elderly patients due to increased risk of GI bleeding and renal impairment.","Avoid in patients with dehydration or hypovolemia.","Use with caution in patients with cardiovascular risk factors.","Do not use for more than 7 days without medical supervision.","Monitor for signs of hepatotoxicity and discontinue if liver enzymes rise.","Avoid concurrent use with other NSAIDs.","Use with caution in patients with asthma.","May impair ability to drive or operate machinery if dizziness occurs."]

🤱 Lactation Safety

Not established from the available information. This medicine is not recommended during breastfeeding as it may pass into breast milk and cause harm to the infant.

💊 Overdose Management

Overdose may cause nausea, vomiting, abdominal pain, drowsiness, and gastrointestinal bleeding. There is no specific antidote. Treatment is supportive and symptomatic. Activated charcoal may be administered if overdose is recent. Monitor vital signs, renal and hepatic function. Seek immediate medical attention.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Always take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it increases the risk of gastrointestinal bleeding. Do not use this medicine if you have a history of peptic ulcer, kidney disease, liver disease, or heart failure. Inform your doctor about all other medications you are taking, especially blood thinners, antihypertensives, and other NSAIDs. Do not take this medicine for more than 7 days without consulting your doctor. If you are pregnant or planning to become pregnant, consult your doctor before taking this medicine. Breastfeeding mothers should avoid this medicine as it may pass into breast milk. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, renal impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended for women planning pregnancy or who are pregnant. Consult your doctor for safe alternatives.

🏥 Post-Surgery Considerations

This medicine is often used post-surgery to reduce swelling and pain. However, it should be used under medical supervision and for a short duration. Inform your surgeon about all medications you are taking.

🦷 Dental Procedures

This medicine may be prescribed after dental procedures to reduce pain and swelling. Take it as directed and inform your dentist about any medical conditions.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Engage in low-impact exercises like swimming or walking.
😴
Practice good posture to prevent musculoskeletal pain.
💧
Include anti-inflammatory foods like omega-3 fatty acids in your diet.
🧘
Get adequate sleep to promote healing.
🌞
Avoid smoking as it can worsen inflammation.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you have pain or swelling. Consult your doctor before starting any exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Stay well hydrated by drinking plenty of water.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some patients. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take rest and avoid strenuous activities during treatment.

🛑 When to Stop This Medicine

Stop taking this medicine if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or signs of liver or kidney problems. Do not stop abruptly without consulting your doctor if you have been on prolonged therapy.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to increased risk of gastrointestinal bleeding, hepatotoxicity, renal impairment, and cardiovascular events. Regular monitoring of liver and kidney function is advised if prolonged use is necessary. Consult your doctor for alternative treatments if symptoms persist.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and swelling.

Evidence: Well-established
RICE therapy (Rest, Ice, Compression, Elevation)

Effective for traumatic edema and pain.

Evidence: Well-established
Acupuncture

May help with pain relief.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. However, consult your doctor before vaccination if you are on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue your regular dosing schedule as prescribed. Check local customs regulations regarding prescription medicines. Always keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with post-operative knee swelling
After knee surgery, the patient was prescribed this medicine for swelling and pain. Within a few days, the swelling reduced significantly, and pain was well controlled. The patient was advised to take it with food and to avoid alcohol. The medicine was stopped after 7 days as symptoms improved.
💡 Lesson: Short-term use with food and adherence to prescribed duration leads to good outcomes.
👤 A 60-year-old with acute sinusitis and facial pain
The patient experienced severe facial pain and congestion due to sinusitis. This medicine was prescribed for 5 days. The patient reported relief in pain and reduction in swelling. However, the patient developed mild nausea, which was managed by taking the medicine with meals.
💡 Lesson: Taking the medicine with food helps manage mild side effects like nausea.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30-60 minutes, but anti-edema effects may take a few days.

Q: Can I take it on an empty stomach?

A: No, it should be taken with food to reduce stomach upset.

Q: Is it safe for long-term use?

A: No, it is only for short-term use, typically not exceeding 7 days, due to risks of liver, kidney, and gastrointestinal side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for infanim ser tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken long-term for chronic pain.
    Fact: This medicine is only for short-term use due to risks of liver, kidney, and gastrointestinal side effects.
  • Myth: This medicine is safe for children.
    Fact: This medicine is not recommended for children below 12 years due to safety concerns.
  • Myth: This medicine can be taken on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset.

🔄 Alternative Options

Generic Alternatives

  • Nimesulide + Serratiopeptidase combination generics

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Nimesulide + Serratiopeptidase","onset":"30-60 minutes","duration":"6-8 hours","key_feature":"Selective COX-2 inhibition with anti-edema action"},{"medicine":"Aceclofenac + Serratiopeptidase","composition":"Aceclofenac + Serratiopeptidase","onset":"30-60 minutes","duration":"8-12 hours","key_feature":"Similar anti-inflammatory and anti-edema action"}]

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