gelikem 480 mg/25 mg suspension - Magaldrate (480mg) + Simethicone (25mg) medicine

Acidcure Syrup: Complete Guide to Uses, Dosage, and Safety

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🏭 Monokem Labs 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of acid indigestion and gas-related bloating.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or black tarry stools
  • Severe or worsening abdominal pain
  • Difficulty swallowing or persistent vomiting
  • Unexplained weight loss with indigestion
  • Chest pain or shortness of breath
  • Swelling of face, lips, or throat
  • Yellowing of eyes or skin

If experiencing severe symptoms, call emergency services immediately.

What is gelikem 480 mg/25 mg suspension used for?

This medicine is an oral antacid and antiflatulent syrup containing magaldrate and simethicone. It neutralises stomach acid and breaks down trapped gas, giving quick relief from heartburn, indigestion, and bloating. It is usually taken in doses of 5 to 10 mL up to four times a day, as advised by a doctor.

  • Generic Name: Magaldrate (480mg) + Simethicone (25mg)
  • Manufacturer: Monokem Labs
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 gelikem 480 mg/25 mg suspension के बारे में (Hindi Summary)

उपयोग: यह दवा मैगल्ड्रेट और सिमेथिकोन का मिश्रण है, जो सीने में जलन, एसिडिटी, खट्टी डकार और पेट में गैस के कारण होने वाली असुविधा में राहत देती है। मैगल्ड्रेट पेट के अतिरिक्त एसिड को संतुलित करता है और सिमेथिकोन गैस के बुलबुले को तोड़कर बाहर निकालने में मदद करता है। यह दवा खाने के बीच या रात में सोने से पहले ली जा सकती है। अगर आपको किडनी की बीमारी है या आप गर्भवती हैं, तो इसे लेने से पहले डॉक्टर से सलाह जरूर लें।

साइड इफेक्ट्स: इस दवा को सही मात्रा में लेने पर आमतौर पर कोई गंभीर दिक्कत नहीं होती। कुछ लोगों को हल्का दस्त, कब्ज, जी मिचलाना या मुँह में चॉक जैसा स्वाद महसूस हो सकता है। ये लक्षण आमतौर पर अपने आप ठीक हो जाते हैं। अगर चेहरे या गले में सूजन, तेज पेट दर्द, या दिल की धड़कन अनियमित लगे, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर या लेबल पर लिखी मात्रा से ज्यादा न लें। हर बार लेने से पहले बोतल को अच्छी तरह हिलाएँ और मापने वाले कप या चम्मच का ही इस्तेमाल करें। अन्य दवाओं के साथ इसे लेने से पहले कम से कम दो घंटे का अंतर रखें। किडनी की बीमारी, हार्ट फेलियर या मैग्नीशियम-अल्युमिनियम से परहेज वाले लोग बिना डॉक्टर की सलाह के इसका इस्तेमाल न करें। दो हफ्ते से ज्यादा लगातार इसका सेवन न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 gelikem 480 mg/25 mg suspension Uses & Benefits

[{"condition":"Heartburn and acid indigestion","description":"Rapidly neutralises excess stomach acid and relieves the burning discomfort behind the breastbone.","evidence":"Well-established"},{"condition":"Gastro-oesophageal reflux symptoms","description":"Provides symptomatic relief from regurgitation and sour taste associated with reflux episodes.","evidence":"Well-established"},{"condition":"Functional dyspepsia with bloating","description":"Reduces upper abdominal fullness and gas-related discomfort after meals.","evidence":"Moderate"},{"condition":"Post-operative gas and abdominal distension","description":"Simethicone helps disperse trapped gas after abdominal surgery when prescribed by the treating team.","evidence":"Limited"},{"condition":"Antacid cover during NSAID therapy","description":"Sometimes used to ease stomach irritation in patients taking pain relievers, though it does not prevent ulcers.","evidence":"Limited"}]

Off-label uses: [{"condition":"Hiccups","description":"Occasionally used to relieve persistent hiccups by reducing gastric distension.","evidence":"Limited"},{"condition":"Preparation before endoscopy","description":"Simethicone-containing products are sometimes given to reduce foam and improve mucosal visibility during upper GI endoscopy.","evidence":"Moderate"}]

Primary treatment for: Acid indigestion and heartburn

Also treats: Gastro-oesophageal reflux disease, Functional dyspepsia, Bloating and flatulence, Gastritis

📋 Drug Information

Generic Name(s)Magaldrate (480mg) + Simethicone (25mg)
Brand Namegelikem 480 mg/25 mg suspension
ManufacturerMonokem Labs
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Do not freeze.
Shelf Life24 months from the date of manufacture, or as printed on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine between meals or at bedtime for best effect.
2
Shake the bottle well before each dose and use a proper measuring cup.
3
Keep a gap of at least two hours between this medicine and other oral drugs.
4
Do not use it for more than two weeks without medical review.
5
If you have kidney disease, ask your doctor before using this medicine.
6
Report persistent bloating or weight loss to your doctor for further evaluation.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Heartburn after meals
This medicine is commonly used for this symptom.
Likely Use
✅
Bloating and excessive belching
Simethicone in this medicine helps relieve gas.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Chest pain with sweating
This could be a heart problem. Seek emergency care immediately.
Not Primary
❌
Blood in stool
This needs urgent medical evaluation, not self-treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMagaldrate is minimally absorbed from the gastrointestinal tract; its action is local in the stomach. Simethicone is not absorbed systemically to any significant extent and is excreted unchanged in the faeces.
DistributionBecause both ingredients act locally and are poorly absorbed, there is no meaningful systemic distribution to body tissues.
Protein BindingNot established from the available information.
MetabolismMagaldrate is not metabolised; it is converted to salts in the stomach. Simethicone is biologically inert and is not metabolised.
Half-LifeNot established from the available information.
ExcretionThe magnesium and aluminium salts formed from magaldrate are largely excreted in the faeces, with small amounts of absorbed magnesium excreted in the urine. Simethicone is excreted unchanged in the faeces.
BioavailabilitySystemic bioavailability is negligible for both magaldrate and simethicone because they act locally in the gut.
Onset of ActionRelief of heartburn usually begins within a few minutes of taking the syrup, while the defoaming effect on gas may take slightly longer.
Peak Plasma TimeNot applicable, as this medicine acts locally and is not absorbed into the bloodstream to a significant degree.
Duration of ActionThe antacid effect generally lasts for about one to two hours, depending on the amount of food in the stomach and the rate of gastric emptying.

How It Works

This medicine works through two complementary actions. Magaldrate is a layered magnesium-aluminium hydroxide complex that reacts with hydrochloric acid in the stomach to form water and harmless salts, thereby lowering gastric acidity without causing a large rebound acid surge. Simethicone is a silicone-based surfactant that reduces the surface tension of gas bubbles in the gastrointestinal tract, causing small bubbles to coalesce into larger ones that are easier to expel by belching or passing flatus. Together they provide both acid neutralisation and relief from gas-related bloating.

Mechanism Steps

1
Acid neutralisation: Magaldrate reacts with gastric hydrochloric acid to form magnesium and aluminium salts and water, raising the stomach pH.
2
Sustained buffering: The layered structure of magaldrate releases antacid activity gradually, giving a longer buffering effect than simple antacids.
3
Defoaming action: Simethicone lowers the surface tension of gas bubbles in the stomach and intestine, allowing small bubbles to merge.
4
Gas expulsion: The larger coalesced bubbles are more easily expelled by belching or passing flatus, reducing bloating and pressure.
5
Symptom relief: The combined reduction in acid irritation and gas pressure relieves heartburn, fullness, and upper abdominal discomfort.

💡 How to Take gelikem 480 mg/25 mg suspension

Strength: Each 5 mL of syrup contains magaldrate 480 mg and simethicone 25 mg.

1Shake the bottle well before each use.
2Measure the prescribed amount using the cup or spoon provided.
3Swallow the syrup slowly; do not dilute it unless advised.
4Take it between meals or as directed by your doctor.
5Rinse your mouth with water after taking the dose.
6Wait at least two hours before taking other oral medicines.

Dosage Information

Adult DosageThe usual adult dose of this syrup is 5 to 10 mL taken between meals and at bedtime, or as directed by a clinician. The dose may be repeated up to four times a day if needed, but the total daily amount should not exceed the label recommendation. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Shake the bottle well and measure with the supplied cup.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageOlder adults may use this medicine at the standard adult dose, but they should be monitored for bowel changes and electrolyte imbalance, especially if they have reduced kidney function or take multiple medicines.
Renal ImpairmentPatients with mild kidney impairment should use this medicine sparingly and under medical advice. In moderate to severe kidney impairment, it is generally avoided because of the risk of magnesium and aluminium accumulation.
Hepatic ImpairmentNo specific dose adjustment is required for liver disease, as the medicine is not metabolised by the liver. However, any underlying liver condition should be discussed with the treating doctor.
Maximum Daily DoseDo not exceed 40 mL in 24 hours unless specifically directed by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take between meals or as advised
Antacids work best when the stomach is not overloaded with food.
Citrus fruits and juices
Avoid taking the dose with them
Acidic foods can reduce the antacid effect.
High-fibre foods
Keep a gap of one to two hours
Fibre can bind the medicine and reduce its action.
Alcohol
Avoid
Alcohol increases acid production and worsens symptoms.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.
📌 You are taking it only when needed for symptoms
→ Take it when symptoms occur.
💡 No fixed schedule is required for as-needed use.

⚠️ Side Effects of gelikem 480 mg/25 mg suspension

✅ Common Side Effects

Loose stools (Common (5-10%))
Usually settles on its own. Reduce the dose or consult your doctor if it persists.
Constipation (Common (5-10%))
Increase fluid and fibre intake. Consult your doctor if it lasts more than a few days.
Nausea (Uncommon (1-5%))
Take the syrup after meals and sip it slowly. Seek advice if vomiting occurs.
Chalky taste (Common (5-10%))
Rinse your mouth with water after each dose. This is harmless.
Abdominal fullness (Uncommon (1-5%))
Avoid large meals and take the medicine at the prescribed time.

🚨 Serious Side Effects

Allergic reaction with facial or throat swelling (Rare (<0.1%))
Stop the medicine and seek emergency medical care immediately.
Severe abdominal pain (Rare (<0.1%))
Stop the medicine and consult a doctor without delay.
Electrolyte disturbance in kidney disease (Rare (<0.1%))
Seek medical review if you notice muscle weakness, confusion, or irregular heartbeat.
Aluminium or magnesium accumulation (Rare (<0.1%))
Patients with kidney impairment should use this medicine only under medical supervision.

⚠️ Rare Side Effects

Milk-alkali syndrome
Prolonged high-dose use with calcium can cause high calcium levels. Seek medical advice if you feel confused or very thirsty.
Hypophosphataemia
Long-term aluminium-containing antacids can lower phosphate. Report persistent weakness to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tetracycline Major
Fluoroquinolones Major
Iron supplements Major
Levothyroxine Major
Ketoconazole Moderate
Atenolol Moderate
Phenytoin Moderate
Digoxin Minor
Aspirin Minor
Vitamin C Minor

🚨 Major Interactions

  • Tetracycline and doxycycline
  • Fluoroquinolone antibiotics
  • Iron supplements
  • Levothyroxine

⚡ Moderate Interactions

  • Ketoconazole and itraconazole
  • Atenolol and other beta-blockers
  • Corticosteroids
  • Phenytoin

🍷 Alcohol Interaction

Alcohol increases gastric acid secretion and can worsen heartburn and gastritis, which may make this medicine seem less effective. It is advisable to avoid alcohol while you are being treated for acid-related symptoms.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to magaldrate, simethicone, or any ingredient of this medicine","Severe kidney impairment or dialysis","Hypermagnesaemia","Severe abdominal pain of unknown cause","Suspected gastrointestinal obstruction or perforation"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose or duration without medical advice.","Use with caution in patients with kidney disease, heart failure, or a magnesium-restricted diet.","Separate this medicine from other oral drugs by at least two hours.","Do not use for more than two weeks for persistent symptoms without consulting a doctor.","Keep out of reach of children.","Shake well before use and measure with a proper cup or spoon."]

🤱 Lactation Safety

Magaldrate and simethicone are poorly absorbed from the gut, so the amount reaching breast milk is expected to be negligible. Short-term use is generally considered compatible with breastfeeding, but medical advice should be sought before regular use.

💊 Overdose Management

Overdose of this medicine is unlikely to cause serious harm in people with normal kidney function, but large amounts can cause diarrhoea, abdominal cramps, or electrolyte imbalance. In patients with kidney disease, overdose can lead to magnesium or aluminium toxicity. Treatment is supportive and symptomatic. If a large amount has been taken, contact a doctor or poison control centre immediately. Do not induce vomiting unless advised by a healthcare professional.

⏰ Missed Dose

This medicine is usually taken when needed for symptoms. If you are on a scheduled dose and miss it, take it as soon as you remember, unless it is almost time for the next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as directed on the label or by your clinician, and do not exceed the stated dose. Shake the bottle well before each use and measure the dose with the supplied cup or a proper measuring spoon. Maintain a gap of at least two hours between this medicine and other oral medicines, because antacids can reduce the absorption of many drugs. If you have kidney problems, heart failure, or are on a magnesium- or aluminium-restricted diet, speak to your doctor before using this product. Do not use it for more than two weeks without medical advice. Keep it out of reach of children, store it at room temperature, and discard it after the expiry date. Pregnant or breastfeeding women should confirm with their doctor before starting this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Older adults are more likely to have reduced kidney function and to take multiple medicines. They should use this medicine sparingly, keep a gap from other drugs, and report any new bowel or muscle symptoms to their doctor.

🤰 Pregnancy Planning (TTC)

If you are trying to conceive or are pregnant, consult your doctor before using this medicine. Short-term use of magnesium-aluminium antacids may be acceptable, but the need and duration should be confirmed by a clinician.

🏥 Post-Surgery Considerations

After abdominal surgery, use this medicine only if your surgeon or treating doctor advises it. Simethicone may help with post-operative gas, but self-medication can mask complications such as obstruction or bleeding.

🦷 Dental Procedures

No specific precautions are required for dental procedures. Inform your dentist about all medicines you take, including this one, as part of your medical history.

💚 Lifestyle Tips for Better Results

🏃
Eat smaller, more frequent meals instead of large heavy meals.
🥗
Avoid spicy, oily, and very acidic foods that trigger your symptoms.
😴
Do not lie down immediately after eating; wait at least two to three hours.
💧
Elevate the head of your bed if you have night-time reflux.
🧘
Maintain a healthy weight and avoid tight clothing around the abdomen.
🌞
Reduce stress with relaxation techniques such as deep breathing or yoga.

🏋️ Exercise Considerations

There is no specific restriction on exercise while taking this medicine. However, vigorous exercise immediately after a heavy meal can worsen reflux and bloating, so allow time for digestion.

🥗 Diet Recommendations

Choose bland, easily digestible foods during flare-ups.
Include fibre-rich fruits and vegetables in moderation.
Limit caffeine, carbonated drinks, and alcohol.
Stay well hydrated with water throughout the day.
Avoid late-night snacks and heavy meals close to bedtime.

💼 Impact on Daily Work & Life

This medicine does not usually cause drowsiness or affect alertness, so it is unlikely to interfere with driving or operating machinery. However, if you feel unwell from the underlying condition, avoid driving until you feel better.

🛑 When to Stop This Medicine

Stop this medicine and consult a doctor if your symptoms do not improve within two weeks, if they worsen, or if you develop red-flag signs such as blood in vomit, black stools, or severe abdominal pain. Do not stop any prescribed treatment for an underlying condition without medical advice.

📅 Long-Term Use Effects

Long-term or excessive use of this medicine can lead to bowel habit changes and, in people with kidney disease, accumulation of magnesium and aluminium. It may also mask more serious conditions such as ulcers or stomach cancer. Regular review with a doctor is advised if symptoms persist beyond two weeks.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary and lifestyle changes

Smaller meals, avoiding trigger foods, and not lying down after eating can reduce acid symptoms.

Evidence: Well-established
Proton pump inhibitors

Prescription medicines that reduce acid production and are used for persistent reflux or ulcers.

Evidence: Well-established
H2 receptor blockers

Another class of acid-reducing medicines for longer symptom control.

Evidence: Well-established
Herbal remedies

Some people try ginger or chamomile, but evidence is limited and they should not replace medical treatment.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There is no known interaction between this medicine and vaccines. You can receive routine vaccinations while taking it.

📦 Storage Guide

✅ DO

Store at room temperature between 15°C and 30°C

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep the bottle tightly closed in its original carton

❌ DON'T

Do not transfer to another container

✅ DO

Keep away from direct sunlight and heat

❌ DON'T

Do not store near a stove or in a hot car

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after the expiry date

✈️ Traveling with This Medicine

Carry this medicine in its original labelled bottle with the prescription copy if you are travelling. Keep it in your hand luggage so that it stays at room temperature and is not exposed to extreme heat or cold in checked baggage. If you are crossing time zones, take the dose as needed for symptoms rather than strictly by clock time. Declare it at customs if required and check the destination country&#039;s rules for liquid medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 38-year-old teacher with frequent evening heartburn and bloating
She was prescribed this medicine after meals and at bedtime. Within a few days her heartburn episodes reduced and the bloating after dinner became much less uncomfortable. She learned to keep a two-hour gap from her thyroid tablet.
💡 Lesson: Taking the antacid at the right time and separating it from other medicines improves both relief and safety.
👤 A 62-year-old man with mild kidney impairment and occasional acidity
He wanted to use this medicine daily for his sour stomach. His doctor advised occasional use only and monitored his kidney function, because magnesium and aluminium can build up when kidneys are weak.
💡 Lesson: People with kidney problems should use antacids only under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Relief usually starts within a few minutes of taking the syrup, though the effect on gas may take a little longer.

Q: Can I take it with other medicines?

A: You should keep a gap of at least two hours between this medicine and other oral drugs, because antacids can reduce their absorption.

Q: Is it safe for long-term use?

A: It is intended for short-term relief. Do not use it for more than two weeks without consulting a doctor.

Q: Can pregnant women take it?

A: Short-term use may be acceptable, but you should always consult your doctor before taking any medicine during pregnancy.

Q: What should I do if I miss a dose?

A: If you are on a scheduled dose, take it when you remember unless it is almost time for the next dose. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine every day?
  • Will it affect my kidney function?
  • Can I take it with my blood pressure medicine?
  • Is it safe during pregnancy?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • How long can I use it safely?

🔄 Substitutes for gelikem 480 mg/25 mg suspension

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antacids can cure stomach ulcers.
    Fact: Antacids only relieve symptoms; ulcers need specific treatment prescribed by a doctor.
  • Myth: More antacid gives faster relief.
    Fact: Taking more than the recommended dose can cause side effects and does not improve relief.
  • Myth: This medicine can be taken with any other medicine at the same time.
    Fact: Antacids can reduce the absorption of many drugs, so a gap of at least two hours is needed.
  • Myth: Antacids are safe for everyone.
    Fact: People with kidney disease or on a magnesium-restricted diet should avoid them unless advised by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Magaldrate and simethicone oral suspension
  • Magaldrate oral suspension
  • Simethicone oral emulsion

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Magaldrate 480 mg + Simethicone 25 mg per 5 mL","onset":"Within minutes","duration":"1-2 hours","best_for":"Heartburn with bloating"},{"medicine":"Aluminium-magnesium antacid","composition":"Aluminium hydroxide + Magnesium hydroxide","onset":"Within minutes","duration":"1-2 hours","best_for":"Simple acid indigestion"},{"medicine":"Calcium carbonate antacid","composition":"Calcium carbonate","onset":"Within minutes","duration":"30-60 minutes","best_for":"Occasional heartburn"},{"medicine":"Simethicone drops","composition":"Simethicone","onset":"Within 30 minutes","duration":"2-3 hours","best_for":"Gas and bloating only"}]

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