dr cold tablet - Caffeine (25mg) + Chlorpheniramine Maleate (2mg) medicine

dr cold tablet

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🏭 Astra Labs 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

What is dr cold tablet used for?

This medicine contains Caffeine (25mg) + Chlorpheniramine Maleate (2mg) and is used to treat RESPIRATORY. Caffeine: Adenosine receptor antagonist; Chlorpheniramine: H1-receptor antagonist. Always consult your doctor before use.

  • Generic Name: Caffeine + Chlorpheniramine Maleate
  • Manufacturer: Astra Labs
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 dr cold tablet Uses & Benefits

Symptomatic relief of allergic rhinitis, common cold, sinusitis.

Off-label uses: None well-established.

📋 Drug Information

Generic Name(s)Caffeine + Chlorpheniramine Maleate
Brand NameAlmolet Tablet
ManufacturerAstra Labs
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + CNS Stimulant
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract.
DistributionDistributes widely throughout the body; crosses blood-brain barrier.
Protein BindingCaffeine: ~35%; Chlorpheniramine: ~70%
MetabolismCaffeine: Hepatic (CYP1A2); Chlorpheniramine: Hepatic (CYP2D6, CYP3A4)
Half-LifeCaffeine: 3-5 hours; Chlorpheniramine: 14-24 hours
ExcretionCaffeine: Renal (primarily as metabolites); Chlorpheniramine: Renal
BioavailabilityCaffeine: ~100%; Chlorpheniramine: ~25-50%
Onset of ActionCaffeine: 15-45 minutes; Chlorpheniramine: 30-60 minutes
Peak Plasma TimeCaffeine: 1-2 hours; Chlorpheniramine: 2-6 hours
Duration of ActionCaffeine: 4-6 hours; Chlorpheniramine: 4-6 hours

How It Works

Caffeine: Adenosine receptor antagonist; Chlorpheniramine: H1-receptor antagonist

Mechanism Steps

1Caffeine blocks adenosine receptors (A1 and A2A), reducing inhibitory neurotransmission and causing CNS stimulation.
2Chlorpheniramine competitively blocks histamine at H1 receptors, reducing allergic symptoms.
3Combination provides relief of cold and allergy symptoms with reduced drowsiness due to caffeine.

💡 How to Take dr cold tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of dr cold tablet

✅ Common Side Effects

Drowsiness
Dry mouth
Nervousness
Insomnia
Dizziness

🚨 Serious Side Effects

Severe allergic reactions
Arrhythmias
Seizures
Urinary retention

⚠️ Rare Side Effects

Blood dyscrasias
Hepatotoxicity
Photosensitivity

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major Increased risk of hypertensive crisis
Fluvoxamine Major Increased caffeine toxicity
Alcohol Moderate Enhanced sedation
Sedatives Moderate Additive CNS depression
Anticholinergics Moderate Increased anticholinergic effects

🚨 Major Interactions

  • MAOIs
  • CYP1A2 inhibitors (e.g., fluvoxamine)
  • CYP2D6 inhibitors (e.g., paroxetine)

⚡ Moderate Interactions

  • Alcohol
  • Sedatives
  • Anticholinergics

🍷 Alcohol Interaction

Increased sedation and CNS depression.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to any component, severe hypertension, hyperthyroidism, glaucoma, urinary retention, concurrent MAOI use.

🤱 Lactation Safety

Caffeine and chlorpheniramine are excreted in breast milk; use with caution.

💊 Overdose Management

Symptomatic and supportive treatment; activated charcoal may be considered; monitor for CNS stimulation and arrhythmias.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

🔄 Substitutes for dr cold tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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