Coldcare 25mg/2mg Tablet: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, tongue, or throat
- Fast, irregular, or pounding heartbeat
- Severe dizziness or fainting
- Seizures or hallucinations
- Inability to urinate
- Yellowing of skin or eyes
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is coldcare 25mg/2mg/500mg/5mg tablet used for?
This medicine is a combination of Caffeine (25mg) and Chlorpheniramine Maleate (2mg) used to treat allergic rhinitis and common cold symptoms. It works by blocking histamine and counteracting drowsiness with caffeine. It is taken orally every 4-6 hours as needed, not exceeding 6 tablets daily.
- Generic Name: Caffeine + Chlorpheniramine Maleate
- Manufacturer: Mestra Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coldcare 25mg/2mg/500mg/5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा कैफीन (25 मिलीग्राम) और क्लोरफेनिरामाइन मेलिएट (2 मिलीग्राम) का संयोजन है। इसका उपयोग एलर्जी राइनाइटिस, सर्दी-जुकाम और अन्य एलर्जी के लक्षणों जैसे छींक, बहती नाक, आंखों में खुजली और पानी आना, और गले में खुजली के इलाज के लिए किया जाता है। क्लोरफेनिरामाइन हिस्टामिन को ब्लॉक करता है, जिससे एलर्जी के लक्षण कम होते हैं, और कैफीन नींद को कम करने में मदद करता है। यह दवा मुंह से ली जाती है और आमतौर पर हर 4-6 घंटे में एक गोली, दिन में 6 गोलियों से अधिक नहीं। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, मतली, और बेचैनी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज या अनियमित दिल की धड़कन, दौरे, मूत्र रोकना, या गंभीर एलर्जी प्रतिक्रिया (चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई) शामिल हो सकते हैं। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आपको ग्लूकोमा, अस्थमा, हृदय रोग, उच्च रक्तचाप, यकृत या गुर्दे की बीमारी, थायरॉइड विकार, मधुमेह, या पेशाब करने में कठिनाई है। यह दवा नींद और चक्कर का कारण बन सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। शराब और अन्य नींद लाने वाली दवाओं के साथ इसका सेवन न करें। 7 दिनों से अधिक इसका उपयोग बिना डॉक्टर की सलाह के न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें। बच्चों की पहुंच से दूर रखें।
💊 coldcare 25mg/2mg/500mg/5mg tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal itching associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief of sneezing, runny nose, and postnasal drip due to colds.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps reduce itching and hives in allergic skin reactions.","evidence":"Well-established"},{"condition":"Allergic conjunctivitis","description":"Reduces itching and tearing of eyes due to allergies.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Insomnia due to allergies","description":"Sometimes used off-label for its sedative effect in allergic patients with sleep disturbance.","evidence":"Limited"},{"condition":"Motion sickness","description":"Occasionally used off-label for prevention of motion sickness due to anticholinergic effects.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Common cold, Urticaria, Allergic conjunctivitis
📋 Drug Information
| Generic Name(s) | Caffeine + Chlorpheniramine Maleate |
| Brand Name | Almolet Tablet |
| Manufacturer | Mestra Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + CNS Stimulant |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Caffeine is a central nervous system stimulant that acts as an adenosine receptor antagonist, which increases alertness and counteracts the sedative effects of chlorpheniramine. Together, they provide symptomatic relief of allergic symptoms while reducing drowsiness.
Mechanism Steps
💡 How to Take coldcare 25mg/2mg/500mg/5mg tablet
Strength: Each tablet contains Caffeine 25mg and Chlorpheniramine Maleate 2mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally every 4 to 6 hours as needed for symptoms, not to exceed 6 tablets in 24 hours. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. Do not self-medicate; follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) are more sensitive to the anticholinergic and sedative effects of Chlorpheniramine Maleate and the stimulant effects of Caffeine. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary based on creatinine clearance. Consult a clinician. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 6 tablets in 24 hours for adults. Do not exceed this dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coldcare 25mg/2mg/500mg/5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Alcohol | Major | |
| Tricyclic antidepressants | Major | |
| Fluoxetine | Moderate | |
| Ciprofloxacin | Moderate | |
| Benztropine | Moderate | |
| Oral contraceptives | Minor | |
| Cimetidine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Alcohol and other CNS depressants
- Tricyclic antidepressants
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
- CYP1A2 inhibitors (e.g., ciprofloxacin, fluvoxamine)
- Anticholinergic drugs (e.g., benztropine, oxybutynin)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can enhance the sedative effects of Chlorpheniramine Maleate and impair your ability to drive or operate machinery. It may also increase the risk of dizziness, drowsiness, and difficulty concentrating.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Chlorpheniramine Maleate, Caffeine, or any component of the formulation","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOIs","Narrow-angle glaucoma","Urinary retention","Severe hypertension","Severe coronary artery disease","Children under 12 years of age (unless directed by a physician)"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with asthma, COPD, or other respiratory conditions.","Use with caution in patients with glaucoma, prostatic hypertrophy, or urinary retention.","Use with caution in patients with cardiovascular disease, hypertension, or hyperthyroidism.","Do not exceed recommended dose or duration of use.","Consult a doctor if symptoms persist beyond 7 days or are accompanied by fever.","Keep out of reach of children."]
🤱 Lactation Safety
Chlorpheniramine Maleate and Caffeine are excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Consult your doctor.
💊 Overdose Management
Overdose may cause severe drowsiness, seizures, tachycardia, hallucinations, and anticholinergic effects. If overdose is suspected, seek emergency medical attention immediately. Treatment is symptomatic and supportive. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have glaucoma, breathing problems such as asthma or COPD, heart disease, high blood pressure, liver or kidney disease, thyroid disorders, diabetes, or difficulty urinating due to an enlarged prostate. This medicine may cause drowsiness and impair your ability to drive or operate machinery. Avoid alcohol and other central nervous system depressants while taking this medicine, as they can increase drowsiness. Do not take this medicine for longer than 7 days without consulting a doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Keep out of reach of children. Do not use in children under 12 years unless directed by a physician.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the anticholinergic and sedative effects of Chlorpheniramine Maleate and the stimulant effects of Caffeine. They may experience increased drowsiness, confusion, dry mouth, and urinary retention. Use with caution and consider lower doses. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Chlorpheniramine Maleate is considered safe in pregnancy (Category B), but caffeine should be limited. Discuss the risks and benefits with your healthcare provider.
🏥 Post-Surgery Considerations
After surgery, use this medicine with caution as it may interact with anesthetics and other medications. Inform your surgeon and anesthesiologist about all medications you are taking. It may increase the risk of sedation and respiratory depression.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may cause dry mouth, which can increase the risk of dental caries. It may also interact with sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness, which can impair your ability to exercise safely. Avoid strenuous exercise or activities requiring balance until you know how the medicine affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring alertness. It is advisable to avoid such activities until you know how it affects you. Inform your employer if your job requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine if your symptoms resolve or if you experience severe side effects. Do not stop abruptly if you have been taking it for a long time without consulting your doctor. Consult your doctor before stopping if you have been on prolonged therapy.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance to the stimulant effects of caffeine and increased sensitivity to the anticholinergic effects of chlorpheniramine. It may also cause dependence on the sedative effects. Regular monitoring of renal and hepatic function is advisable for prolonged use. Consult your doctor if you need to use it for more than 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Identifying and avoiding triggers can reduce the need for medication.
Evidence: Well-establishedHelps clear nasal passages and reduce congestion.
Evidence: Well-establishedLess sedating alternatives like loratadine or cetirizine.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for allergy testing, stop this medicine at least 3-7 days before testing as it may interfere with results. Consult your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medications. Do not pack it in checked luggage; keep it in your carry-on bag.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after oral administration.
A: Yes, but it may cause drowsiness. Some people find it helpful for sleep, but caffeine may interfere with sleep in others.
A: Consult your doctor or pharmacist before combining with other cold medicines to avoid duplicate ingredients and interactions.
A: Do not use for more than 7 days without consulting a doctor. Prolonged use may lead to tolerance and other side effects.
🤔 Common Patient Concerns
🔄 Substitutes for coldcare 25mg/2mg/500mg/5mg tablet
View AllAlternative brands with exact same active ingredient:
-
forcol-d tabletMount Mettur Pharmaceuticals Ltd ₹8.06 57% CHEAPER
-
kofcold tabletSynokem Pharmaceuticals Ltd ₹15.83 15.6% CHEAPER
-
hikold tabletHinglaj Laboratories ₹15.94 15% CHEAPER
-
Rupar Cold TabletMedispan Ltd ₹19.05 1.6% COSTLIER
-
yoyocold tabletSlaney Healthcare ₹20.63 10% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for children under 12.
Fact: This medicine is not recommended for children under 12 years unless directed by a physician. - Myth: It can be taken with alcohol without any issues.
Fact: Alcohol increases sedation and impairs motor skills; avoid concurrent use. - Myth: It is a cure for the common cold.
Fact: It only relieves symptoms; it does not cure the cold or shorten its duration.
🔄 Alternative Options
Generic Alternatives
- Caffeine + Chlorpheniramine Maleate combination tablets