Pharmalgin 25mg/500mg Tablet: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes (jaundice)
- Severe abdominal pain or vomiting blood
- Blood in stool or black, tarry stools
- Difficulty breathing or swelling of the face, lips, or throat
- Severe skin rash with blisters or peeling
- Decreased urine output or inability to urinate
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is pharmalgin 25mg/500mg tablet used for?
This medicine is a combination of Paracetamol 500 mg and Caffeine 25 mg used for the relief of mild to moderate pain and fever. It works by reducing pain signals in the brain and enhancing the pain-relieving effect of Paracetamol. It is intended for short-term use in adults and adolescents over 12 years.
- Generic Name: Caffeine (25mg) + Paracetamol (500mg)
- Manufacturer: Suzikem Drugs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 pharmalgin 25mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल 500 मिलीग्राम और कैफीन 25 मिलीग्राम का संयोजन है। इसका उपयोग हल्के से मध्यम दर्द जैसे सिरदर्द, दांत दर्द, मासिक धर्म में होने वाले दर्द, मांसपेशियों में दर्द और बुखार को कम करने के लिए किया जाता है। यह दवा दर्द को कम करने और बुखार को नीचे लाने में मदद करती है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, पेट में असहजता, बेचैनी और नींद न आना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें एलर्जी, त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई और लीवर की क्षति शामिल हो सकती है। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का सेवन डॉक्टर के बताए अनुसार ही करें। निर्धारित मात्रा से अधिक न लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे लीवर को नुकसान हो सकता है। पैरासिटामोल युक्त अन्य दवाओं के साथ इसका सेवन न करें। यदि आपको लीवर या किडनी की बीमारी है तो डॉक्टर से सलाह लें। इस दवा को बच्चों की पहुंच से दूर रखें।
💊 pharmalgin 25mg/500mg tablet Uses & Benefits
[{"condition":"Tension headache","description":"Relieves mild to moderate headache pain by reducing pain signals in the brain.","evidence":"Well-established"},{"condition":"Migraine headache","description":"Helps alleviate acute migraine pain, especially when taken early.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides temporary relief from toothache and post-dental procedure pain.","evidence":"Well-established"},{"condition":"Menstrual cramps","description":"Reduces pain associated with menstruation.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Eases minor muscle aches and strains.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces elevated body temperature due to infections or other causes.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Post-operative pain","description":"Sometimes used as an adjunct for mild post-operative pain management.","evidence":"Limited"},{"condition":"Osteoarthritis pain","description":"May be used for short-term relief of osteoarthritis pain when other options are unsuitable.","evidence":"Limited"}]
Primary treatment for: Pain and fever
Also treats: Headache, Toothache, Menstrual cramps, Muscle aches, Cold and flu symptoms
📋 Drug Information
| Generic Name(s) | Caffeine (25mg) + Paracetamol (500mg) |
| Brand Name | pharmalgin 25mg/500mg tablet |
| Manufacturer | Suzikem Drugs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Paracetamol reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system. It acts primarily on the hypothalamus to lower fever and on pain pathways to increase the pain threshold. Caffeine is a central nervous system stimulant that blocks adenosine receptors, leading to increased alertness and enhanced analgesic effect of Paracetamol. The combination provides faster and more effective pain relief than Paracetamol alone.
Mechanism Steps
💡 How to Take pharmalgin 25mg/500mg tablet
Strength: Each tablet contains Caffeine 25 mg and Paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 1 to 2 tablets taken orally every 4 to 6 hours as needed for pain or fever. Do not exceed 8 tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use for more than 3 days for fever or 10 days for pain without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use with caution and follow the doctor's advice. Dose adjustment may be necessary based on liver and kidney function. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose adjustment may be required. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose reduction or avoidance may be necessary. Consult your doctor. |
| Maximum Daily Dose | For adults and adolescents over 12 years: Do not exceed 8 tablets (4000 mg Paracetamol and 200 mg Caffeine) in 24 hours. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of pharmalgin 25mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Rifampicin | Moderate | |
| Isoniazid | Moderate | |
| Other Paracetamol products | Major | |
| Caffeine-containing products | Moderate | |
| Antacids | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Warfarin
- Alcohol
- Other Paracetamol-containing products
⚡ Moderate Interactions
- Carbamazepine, Phenytoin, Rifampicin
- Isoniazid
- Caffeine-containing products (e.g., coffee, energy drinks)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Combining alcohol with Paracetamol increases the risk of severe liver damage. Even moderate alcohol consumption can enhance the toxic effects of Paracetamol on the liver.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Paracetamol, Caffeine, or any component of the formulation","Severe liver disease or active liver failure","Severe kidney disease","Chronic alcoholism","Children under 12 years of age (unless directed by a doctor)"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose. Taking more than the recommended dose can cause serious liver damage.","Avoid alcohol while taking this medicine.","Do not use for more than 3 days for fever or 10 days for pain without consulting a doctor.","Consult a doctor before use if you have liver or kidney disease, or if you are pregnant or breastfeeding.","This medicine may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how it affects you.","Keep out of reach of children."]
🤱 Lactation Safety
Paracetamol and Caffeine are excreted in breast milk in small amounts. This medicine is generally considered compatible with breastfeeding when used at recommended doses. Consult your doctor for guidance.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage, which may be delayed. Symptoms of overdose may include nausea, vomiting, abdominal pain, and loss of appetite. If you suspect an overdose, seek immediate medical attention even if you feel well. The antidote, N-acetylcysteine, is most effective when given within 8-10 hours of overdose. Do not wait for symptoms to appear.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as directed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid consuming alcohol while taking this medicine as it increases the risk of liver damage. Do not take other products containing Paracetamol simultaneously to prevent overdose. If you have liver or kidney disease, consult your doctor before use. This medicine may cause dizziness or drowsiness in some individuals; avoid driving or operating heavy machinery until you know how it affects you. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. If symptoms persist for more than 3 days or worsen, seek medical attention.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. They may also have reduced liver and kidney function, which can affect drug clearance. Use with caution and follow the doctor's advice. Dose adjustment may be necessary.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Paracetamol is generally considered safe during pregnancy when used at recommended doses for short periods, but Caffeine should be limited. Your doctor can advise on the safest options for pain relief.
🏥 Post-Surgery Considerations
This medicine may be used for mild post-operative pain, but it should not replace prescribed pain management. Consult your surgeon before taking any over-the-counter medicine after surgery, as it may interact with other medications.
🦷 Dental Procedures
This medicine can provide temporary relief from dental pain before or after procedures. However, it is not a substitute for dental treatment. Inform your dentist if you are taking this medicine, especially if you are scheduled for surgery or have a history of liver disease.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or drowsiness in some individuals. Avoid strenuous exercise or activities requiring high alertness until you know how the medicine affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe for office work, but if you experience restlessness or insomnia, adjust the timing of your dose.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your pain or fever persists for more than 3 days (fever) or 10 days (pain), if symptoms worsen, or if you experience any serious side effects such as allergic reactions, yellowing of skin or eyes, or severe abdominal pain. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine, especially at high doses, can increase the risk of liver damage and kidney impairment. Regular monitoring of liver and kidney function may be required if used for extended periods. It is not recommended for chronic pain management without medical supervision. Consult your doctor if you need to use this medicine for more than 10 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help manage chronic pain through exercises and manual techniques.
Evidence: Well-establishedStress reduction methods like meditation can help reduce tension headaches.
Evidence: ModerateApplying heat or cold to the affected area can provide local pain relief.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. It can be taken before or after vaccination if needed for pain or fever. However, consult your doctor if you have any concerns.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medicines in your destination country. Keep it in your carry-on luggage if flying.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it orally.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.
A: This medicine is intended for short-term use. Do not take it for more than 3 days for fever or 10 days for pain without consulting a doctor.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Do not take other Paracetamol-containing products simultaneously. Consult your doctor before combining with other painkillers.
🤔 Common Patient Concerns
🔄 Substitutes for pharmalgin 25mg/500mg tablet
View AllAlternative brands with exact same active ingredient:
-
glycodin activ tabletAlembic Pharmaceuticals Ltd ₹13.43 4.5% CHEAPER
-
coldie ex tabletBiochem Pharmaceutical Industries ₹26.25 86.7% COSTLIER
-
dolopar tabletMicro Labs Ltd ₹59.06 320.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe to take in any amount.
Fact: Taking more than the recommended dose can cause severe liver damage. - Myth: This medicine can be taken with alcohol without any risk.
Fact: Alcohol increases the risk of liver damage when taken with this medicine. - Myth: This medicine is a strong painkiller like opioids.
Fact: This medicine is a mild analgesic and does not contain opioids.
🔄 Alternative Options
Generic Alternatives
- Paracetamol 500 mg + Caffeine 25 mg tablet