doxopil 400mg tablet
What is doxopil 400mg tablet used for?
Amril Plus 400mg Tablet (Doxofylline) is used to treat RESPIRATORY. It contains Doxofylline (400mg), which Inhibits phosphodiesterase (PDE) enzymes, leading to increased intracellular cAM. Always consult your doctor before use. Take as prescribed.
- Generic Name: Doxofylline
- Manufacturer: Psychotropics India Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ doxopil 400mg tablet Uses & Benefits
Bronchial asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis
Off-label uses: None established
๐ Drug Information
| Generic Name(s) | Doxofylline |
| Brand Name | Amril Plus 400mg Tablet |
| Manufacturer | Psychotropics India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Theophylline & its derivatives |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits phosphodiesterase (PDE) enzymes, leading to increased intracellular cAMP and cGMP, resulting in bronchodilation and anti-inflammatory effects
Mechanism Steps
๐ก How to Take doxopil 400mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of doxopil 400mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Headache
- Insomnia
- Dizziness
- Tachycardia
๐จ Serious Side Effects
- Seizures
- Arrhythmias
- Severe hypotension
- Hypersensitivity reactions
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Nephrotoxicity
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Theophylline | Major | Increased risk of toxicity |
| Cimetidine | Major | Reduced clearance of doxofylline |
| Ciprofloxacin | Major | Increased doxofylline levels |
| Erythromycin | Major | Increased doxofylline levels |
| Fluvoxamine | Major | Increased doxofylline levels |
| Lithium | Moderate | Increased lithium levels |
| Beta-blockers | Moderate | Antagonism of bronchodilator effect |
| Phenytoin | Moderate | Decreased doxofylline levels |
| Carbamazepine | Moderate | Decreased doxofylline levels |
| Caffeine | Minor | Additive stimulant effects |
| Alcohol | Minor | Increased CNS side effects |
| Smoking | Minor | Increased metabolism of doxofylline |
๐จ Major Interactions
- Theophylline
- Cimetidine
- Ciprofloxacin
- Erythromycin
- Fluvoxamine
โก Moderate Interactions
- Lithium
- Beta-blockers
- Phenytoin
- Carbamazepine
โน๏ธ Minor Interactions
- Caffeine
- Alcohol
- Smoking
๐ฝ๏ธ Food Interactions
High-fat meals may delay absorption; avoid excessive caffeine intake
๐ท Alcohol Interaction
May increase risk of side effects like dizziness and headache
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to doxofylline or any excipients, acute myocardial infarction, hypotension, seizure disorders
๐ Monitoring Parameters
Liver function tests, renal function, serum doxofylline levels (if toxicity suspected), ECG in elderly or cardiac patients
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Gastric lavage, activated charcoal, symptomatic treatment; monitor cardiac and CNS effects
โฐ Missed Dose
Take as soon as remembered unless almost time for next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for doxopil 400mg tablet
View AllAlternative brands with exact same active ingredient (Doxofylline (400mg)):
-
ventidox 400 mg tabletMankind Pharma Ltd โน13.36 24% CHEAPER
-
microphylline tabletMicro Labs Ltd โน16.69 5.1% CHEAPER
-
davaindia doxofylline 400mg tabletDavaindia Generic Pharmacy โน30.00 70.6% COSTLIER
-
doxiba 400 mg tabletFDC Ltd โน30.94 76% COSTLIER
-
doxomax 400mg tabletAristo Pharmaceuticals Pvt Ltd โน35.91 104.3% COSTLIER
-
doxovent tabletGlenmark Pharmaceuticals Ltd โน38.44 118.7% COSTLIER
-
doxosubh 400mg tabletBen Pharmaceuticals โน40.00 127.5% COSTLIER
-
doxymont 400mg tabletOrganic Nova Pharmaceuticals โน40.31 129.3% COSTLIER
-
pulmodox 400mg tabletTTK Healthcare Ltd โน40.57 130.8% COSTLIER
-
Fycon 400mg TabletTrends Pharma Pvt Ltd โน40.58 130.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.