Doxovent Tablet (Doxofylline 400mg): Complete Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction with swelling of the face, lips, or throat
- Irregular or very fast heartbeat
- Seizures or convulsions
- Severe chest pain or difficulty breathing
- Blood in vomit or black, tarry stools
- Yellowing of the skin or eyes (jaundice)
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is microphylline tablet used for?
This medicine is a bronchodilator used to treat asthma and COPD. It works by relaxing the muscles in the airways to make breathing easier. It is taken orally, usually once or twice daily, and should not be used for sudden breathing attacks.
- Generic Name: Doxofylline (400mg)
- Manufacturer: Micro Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 microphylline tablet के बारे में (Hindi Summary)
उपयोग: यह दवा दमा (अस्थमा) और क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिजीज (सीओपीडी) के इलाज में इस्तेमाल की जाती है। यह सांस की नलियों की मांसपेशियों को ढीला करके सांस लेने में आसानी करती है। यह दवा सांस फूलने, घरघराहट और छाती में जकड़न जैसे लक्षणों को कम करने में मदद करती है। यह दवा अचानक होने वाले दमे के दौरे के लिए नहीं है, बल्कि लंबे समय तक सांस की समस्या को नियंत्रित करने के लिए दी जाती है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे मतली, उल्टी, पेट दर्द, सिरदर्द, बेचैनी और नींद न आना। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी दिल की धड़कन तेज हो सकती है या चक्कर आ सकते हैं। गंभीर दुष्प्रभाव बहुत कम होते हैं, लेकिन अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, या दौरे पड़ें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं के बारे में बताएं, खासकर दिल, लीवर, किडनी या दौरे की समस्या। अपने डॉक्टर को अपनी सभी दवाओं के बारे में भी बताएं। इस दवा के साथ शराब न पिएं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक गाड़ी न चलाएं। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। डॉक्टर की सलाह के बिना दवा लेना अचानक बंद न करें।
💊 microphylline tablet Uses & Benefits
[{"condition":"Asthma","description":"This medicine helps to control breathing difficulties in people with asthma by relaxing the airways and reducing inflammation.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"This medicine is used to relieve symptoms of COPD, such as wheezing and shortness of breath, and to improve lung function.","evidence":"Well-established"},{"condition":"Bronchospasm","description":"This medicine helps to relieve bronchospasm, which is a sudden narrowing of the airways that makes breathing difficult.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Apnea of prematurity","description":"Sometimes used off-label in premature infants to stimulate breathing, but this is not a standard use and requires specialist supervision.","evidence":"Limited"}]
Primary treatment for: Asthma and COPD
Also treats: Chronic bronchitis, Emphysema
📋 Drug Information
| Generic Name(s) | Doxofylline (400mg) |
| Brand Name | microphylline tablet |
| Manufacturer | Micro Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Theophylline & its derivatives |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | Not established from the available information. Check the expiry date on the package. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the enzyme phosphodiesterase, which leads to an increase in cyclic AMP (cAMP) levels inside certain cells. Higher cAMP levels cause the smooth muscles in the airways to relax, which widens the breathing passages. This medicine also blocks adenosine receptors, which helps to reduce airway sensitivity and inflammation. Additionally, it improves the movement of tiny hair-like structures in the airways called cilia, helping to clear mucus. Overall, these actions make breathing easier for people with asthma or COPD.
Mechanism Steps
💡 How to Take microphylline tablet
Strength: Doxofylline 400 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one 400 mg tablet taken orally once or twice daily, depending on your condition and your doctor's recommendation. The exact dose and frequency must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change your dose without consulting your doctor. Take this medicine at the same time each day to get the most benefit. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Your doctor may start with a lower dose and adjust gradually based on your response and kidney function. Regular monitoring is recommended. |
| Renal Impairment | Dose adjustment may be needed in patients with kidney impairment. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Dose adjustment may be needed in patients with liver impairment. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of microphylline tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ciprofloxacin | Major | |
| Erythromycin | Major | |
| Propranolol | Major | |
| Phenytoin | Moderate | |
| Rifampicin | Moderate | |
| Cimetidine | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Ciprofloxacin
- Erythromycin
- Propranolol
⚡ Moderate Interactions
- Phenytoin
- Rifampicin
- Cimetidine
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase the risk of side effects such as dizziness, drowsiness, and stomach upset. It may also worsen your breathing condition. It is best to avoid alcohol completely during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to Doxofylline or any other methylxanthine derivatives","Acute myocardial infarction (heart attack)","Unstable angina","Severe cardiac arrhythmias","Severe liver disease","Severe kidney disease","Children under 12 years of age (safety not established)"]
⚠️ Warnings & Precautions
["Use with caution in patients with heart disease, high blood pressure, or irregular heartbeat.","Use with caution in patients with liver or kidney impairment. Dose adjustment may be needed.","Use with caution in patients with a history of seizures.","Avoid alcohol while taking this medicine.","Do not drive or operate machinery until you know how this medicine affects you.","Do not stop taking this medicine suddenly without consulting your doctor.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children."]
🤱 Lactation Safety
Not established from the available information. It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe nausea, vomiting, restlessness, rapid heartbeat, seizures, and irregular heartbeat. Treatment is supportive and may include activated charcoal, monitoring of vital signs, and management of symptoms. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before you start taking this medicine, tell your doctor about all your medical conditions, especially heart problems, liver disease, kidney disease, or a history of seizures. Also, inform your doctor about all other medicines you are taking, including over-the-counter products and herbal supplements, because this medicine can interact with some of them. Do not drink alcohol while taking this medicine, as it can increase the risk of side effects. Avoid driving or operating heavy machinery until you know how this medicine affects you. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine. Do not stop taking this medicine suddenly without your doctor's advice, as your breathing symptoms may worsen. Keep all your follow-up appointments so your doctor can monitor your progress and adjust your dose if needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially cardiac effects. Your doctor may start with a lower dose and monitor you closely. Regular check-ups of heart, liver, and kidney function are recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the benefits and risks and may recommend alternative treatments.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with anesthetic agents and affect heart rate. Your doctor may advise you to stop the medicine temporarily before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may cause dry mouth or interact with certain medications used in dentistry. Your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can exercise while taking this medicine, but avoid strenuous activity in cold, dry, or polluted air, as it may trigger breathing problems. Warm up gradually and carry your rescue inhaler if prescribed. If you experience shortness of breath, chest pain, or dizziness during exercise, stop and rest. Consult your doctor before starting a new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, restlessness, or insomnia in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe to continue your normal daily activities, but if you experience side effects that interfere with your work, consult your doctor. Your breathing symptoms should improve with regular use, which may enhance your overall quality of life.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your condition worsens, contact your doctor immediately. Your doctor will decide if and when to stop the medicine or change your treatment plan.
📅 Long-Term Use Effects
Long-term use of this medicine may require regular monitoring of heart, liver, and kidney function. Some patients may develop tolerance, reducing its effectiveness over time. Your doctor may adjust the dose or recommend alternative treatments if needed. It is important to attend regular follow-up appointments to monitor your response and detect any potential side effects early.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
These are often used as controller medications for asthma and COPD and can be used alongside or instead of oral bronchodilators.
Evidence: Well-establishedOral medications like montelukast can help control asthma symptoms and may be an alternative for some patients.
Evidence: Well-establishedA program of exercise, education, and support that can improve breathing and quality of life for people with COPD.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
It is important to stay up to date with vaccinations, especially influenza and pneumococcal vaccines, as respiratory infections can worsen asthma and COPD. Consult your doctor about the best timing for vaccinations while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, consult your doctor about how to adjust your dosing schedule. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may take several days to weeks to show its full effect. It is not for immediate relief of sudden breathing attacks.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor before taking it if you are pregnant or planning to become pregnant.
A: No, do not stop taking this medicine without consulting your doctor. Your symptoms may worsen if you stop suddenly.
🤔 Common Patient Concerns
🔄 Substitutes for microphylline tablet
View AllAlternative brands with exact same active ingredient:
-
ventidox 400 mg tabletMankind Pharma Ltd ₹13.36 20% CHEAPER
-
doxopil 400mg tabletPsychotropics India Ltd ₹17.58 5.3% COSTLIER
-
davaindia doxofylline 400mg tabletDavaindia Generic Pharmacy ₹30.00 79.7% COSTLIER
-
doxiba 400 mg tabletFDC Ltd ₹30.94 85.4% COSTLIER
-
doxomax 400mg tabletAristo Pharmaceuticals Pvt Ltd ₹35.91 115.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for immediate relief of sudden breathing attacks.
Fact: This medicine is not a rescue inhaler and should not be used for sudden attacks. It is for long-term control of breathing symptoms. - Myth: This medicine is safe for everyone.
Fact: This medicine is not safe for people with certain heart conditions, liver disease, or kidney disease. It should only be used under a doctor's supervision. - Myth: You can stop taking this medicine once you feel better.
Fact: You should not stop taking this medicine without consulting your doctor, as your symptoms may worsen.
🔄 Alternative Options
Generic Alternatives
- Doxofylline 400 mg tablet
Brand Alternatives
- Doxovent 400 mg tablet
- Doxofylline 400 mg tablet by other manufacturers