ambropil br syrup - Ambroxol (15mg/5ml) + Terbutaline (2.5mg/5ml) medicine

ambropil br syrup

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🏭 Psychotropics India Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is ambropil br syrup used for?

This medicine contains Ambroxol (15mg/5ml) + Terbutaline (2.5mg/5ml) and is used to treat RESPIRATORY. Ambroxol increases mucus clearance by stimulating surfactant production and reducing mucus viscosity. Always consult your doctor before use.

  • Generic Name: Ambroxol + Terbutaline
  • Manufacturer: Psychotropics India Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ambropil br syrup Uses & Benefits

Acute and chronic respiratory conditions with excessive mucus and bronchospasm (e.g., COPD, asthma, bronchitis)

Off-label uses: Neonatal respiratory distress syndrome (ambroxol), cough associated with upper respiratory infections

📋 Drug Information

Generic Name(s)Ambroxol + Terbutaline
Brand NameAmbropil BR Syrup
ManufacturerPsychotropics India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Bronchodilator
Route of AdministrationOral
StorageStore at room temperature (15-30°C), protect from light
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract
DistributionDistributes widely in body tissues
Protein BindingAmbroxol: ~90%; Terbutaline: ~20%
MetabolismAmbroxol: Hepatic (glucuronidation); Terbutaline: Hepatic (sulfation)
Half-LifeAmbroxol: 3-4 hours; Terbutaline: 3-4 hours
ExcretionAmbroxol: Renal (90%); Terbutaline: Renal (60% unchanged)
BioavailabilityAmbroxol: ~70%; Terbutaline: ~15-25%
Onset of ActionAmbroxol: 30 minutes; Terbutaline: 15-30 minutes
Peak Plasma TimeAmbroxol: 1-2 hours; Terbutaline: 2-4 hours
Duration of ActionAmbroxol: 6-8 hours; Terbutaline: 4-6 hours

How It Works

Ambroxol increases mucus clearance by stimulating surfactant production and reducing mucus viscosity; Terbutaline stimulates beta-2 adrenergic receptors causing bronchodilation.

Mechanism Steps

1Ambroxol stimulates surfactant production in type II pneumocytes
2Ambroxol reduces mucus viscosity by breaking disulfide bonds in mucoproteins
3Terbutaline binds to beta-2 adrenergic receptors on bronchial smooth muscle
4Activation of adenylate cyclase increases cAMP
5cAMP causes relaxation of bronchial smooth muscle
6Improved mucociliary clearance and bronchodilation

💡 How to Take ambropil br syrup

Follow your doctor's prescription exactly.

⚠️ Side Effects of ambropil br syrup

✅ Common Side Effects

Nausea
Vomiting
Diarrhea
Headache
Tremor
Palpitations
Cough

🚨 Serious Side Effects

Hypokalemia
Cardiac arrhythmias
Paradoxical bronchospasm
Severe allergic reactions

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Anaphylaxis
Hepatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major Increased risk of hypertensive crisis
Beta-blockers Major Antagonism of bronchodilator effect
Diuretics Moderate Hypokalemia risk
Corticosteroids Moderate Additive hypokalemia
Xanthine derivatives Moderate Increased CNS stimulation
Anticholinergics Minor Additive anticholinergic effects
Other sympathomimetics Minor Increased cardiovascular effects

🚨 Major Interactions

  • MAOIs
  • Beta-blockers

⚡ Moderate Interactions

  • Diuretics
  • Corticosteroids
  • Xanthine derivatives

🍷 Alcohol Interaction

Avoid alcohol; may increase CNS depression

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, hypertrophic obstructive cardiomyopathy, tachyarrhythmias, severe hyperthyroidism

🤱 Lactation Safety

Use with caution; excreted in breast milk

💊 Overdose Management

Symptomatic and supportive; consider activated charcoal, monitor cardiac function

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

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