dobact tablet - Uses, Price, Side Effects & Substitutes
What is dobact tablet used for?
Ceedoxy TZ (Doxycycline + Tinidazole) is used to treat GASTRO INTESTINAL. It contains Doxycycline (100mg) + Tinidazole (600mg), which Doxycycline inhibits bacterial protein synthesis by binding to 30S ribosomal sub. Always consult your doctor before use. Take as prescribed.
- Generic Name: Doxycycline + Tinidazole
- Manufacturer: Tidal Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ dobact tablet Uses & Benefits
Gastrointestinal infections (e.g., traveler's diarrhea, amebiasis, giardiasis); pelvic inflammatory disease; periodontitis; acne (doxycycline component)
Off-label uses: Malaria prophylaxis (doxycycline); bacterial vaginosis (tinidazole)
๐ Drug Information
| Generic Name(s) | Doxycycline + Tinidazole |
| Brand Name | Ceedoxy TZ |
| Manufacturer | Tidal Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibiotic + Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Doxycycline inhibits bacterial protein synthesis by binding to 30S ribosomal subunit; Tinidazole inhibits DNA synthesis and causes DNA strand breakage in protozoa and anaerobic bacteria
Mechanism Steps
๐ก How to Take dobact tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of dobact tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Metallic taste
- Photosensitivity
- Headache
- Dizziness
๐จ Serious Side Effects
- Pseudomembranous colitis
- Stevens-Johnson syndrome
- Hepatotoxicity
- Intracranial hypertension
- Blood dyscrasias
โ ๏ธ Rare Side Effects
- Esophagitis
- Pancreatitis
- Peripheral neuropathy
- Disulfiram-like reaction with alcohol
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Oral contraceptives | Major | Reduced contraceptive efficacy |
| Antacids | Major | Reduced doxycycline absorption |
| Iron supplements | Major | Reduced doxycycline absorption |
| Barbiturates | Major | Decreased doxycycline half-life |
| Carbamazepine | Major | Decreased doxycycline half-life |
| Phenytoin | Major | Decreased doxycycline half-life |
| Alcohol | Major | Disulfiram-like reaction with tinidazole |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Lithium | Moderate | Increased lithium levels |
| Digoxin | Moderate | Increased digoxin levels |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Penicillins | Minor | Antagonism of bactericidal effect |
| Cimetidine | Minor | Increased tinidazole levels |
๐จ Major Interactions
- Warfarin
- Oral contraceptives
- Antacids containing aluminum, calcium, magnesium
- Iron supplements
- Bismuth subsalicylate
- Barbiturates
- Carbamazepine
- Phenytoin
- Alcohol
โก Moderate Interactions
- Methotrexate
- Lithium
- Digoxin
- Cyclosporine
- Tetracyclines
โน๏ธ Minor Interactions
- Penicillins
- Cimetidine
๐ฝ๏ธ Food Interactions
Avoid dairy products, antacids, and iron supplements within 2-3 hours of doxycycline; food may reduce absorption of doxycycline
๐ท Alcohol Interaction
Avoid alcohol during and for 3 days after tinidazole therapy due to disulfiram-like reaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to tetracyclines or nitroimidazoles; pregnancy; lactation; children under 8 years (doxycycline); severe hepatic impairment
๐ Monitoring Parameters
Liver function tests; renal function; blood counts; signs of superinfection
๐คฑ Lactation Safety
Doxycycline: Excreted in milk, avoid; Tinidazole: Excreted in milk, avoid
๐ Overdose Management
Gastric lavage; supportive care; no specific antidote
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose