Dobact Dox 100 mg/100 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe or bloody diarrhoea with fever or abdominal cramps
- Severe headache with blurred vision or vomiting
- Swelling of the face, lips, or throat, or difficulty in breathing
- Widespread skin rash, blisters, or peeling skin
- Yellowing of the eyes or skin, dark urine, or severe tiredness
- Chest pain, palpitations, or fainting
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is dobact dox 100 mg/100 mg tablet used for?
This medicine is a prescription oral tablet containing doxycycline 100 mg and bromelain 100 mg. Doxycycline is an antibiotic that stops bacterial growth, while bromelain is a pineapple-derived enzyme that helps reduce swelling and inflammation. It is commonly used for dental, sinus, and skin infections with associated swelling. Take it with water, stay upright for thirty minutes, avoid antacids and iron within two hours, and complete the full course as prescribed.
- Generic Name: Doxycycline + Bromelain
- Manufacturer: Tidal Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dobact dox 100 mg/100 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डॉक्सीसाइक्लिन 100 मिलीग्राम और ब्रोमेलेन 100 मिलीग्राम का संयोजन है। डॉक्सीसाइक्लिन एक एंटीबायोटिक है जो बैक्टीरिया की वृद्धि रोकता है, और ब्रोमेलेन अनानास से प्राप्त एक एंजाइम है जो सूजन और दर्द कम करने में मदद करता है। यह दवा मुख्य रूप से दांतों और मसूड़ों के संक्रमण, साइनसाइटिस, त्वचा के संक्रमण और मामूली सर्जरी के बाद होने वाली सूजन के इलाज के लिए दी जाती है। इसे डॉक्टर के बताए अनुसार पूरा कोर्स करना बहुत जरूरी है। दवा को एक गिलास पानी के साथ निगलें और लेने के बाद कम से कम तीस मिनट तक सीधे बैठे या खड़े रहें। दूध, एंटासिड, आयरन, कैल्शियम या जिंक की गोलियों के साथ इसे न लें, क्योंकि इससे दवा का असर कम हो सकता है। धूप में जाते समय सनस्क्रीन और पूरे कपड़े पहनें। गर्भवती महिलाएं, स्तनपान कराने वाली माताएं और आठ साल से छोटे बच्चे इस दवा को बिना डॉक्टर की सलाह के न लें।
साइड इफेक्ट्स: इस दवा के सबसे आम दुष्प्रभाव पेट से जुड़े होते हैं, जैसे जी मिचलाना, उल्टी, दस्त, पेट दर्द और भूख कम लगना। कुछ लोगों को सीने में जलन या गले में जलन महसूस हो सकती है, खासकर अगर दवा कम पानी के साथ ली जाए। धूप के प्रति त्वचा की संवेदनशीलता बढ़ सकती है, जिससे जल्दी सनबर्न हो सकता है। कभी-कभी जीभ पर छाले या कालापन, और महिलाओं में योनि में खुजली या स्राव हो सकता है। ब्रोमेलेन से एलर्जी उन लोगों में हो सकती है जिन्हें अनानास से एलर्जी है। गंभीर लेकिन दुर्लभ दुष्प्रभावों में तेज दस्त, सिर के अंदर दबाव बढ़ना, लिवर की समस्या और त्वचा पर गंभीर प्रतिक्रिया शामिल हैं। सांस लेने में तकलीफ, चेहरे या गले में सूजन, या पूरे शरीर पर दाने होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। हमेशा एक पूरा गिलास पानी के साथ लें और दवा लेने के बाद कम से कम तीस मिनट तक लेटें नहीं। पेट की जलन कम करने के लिए इसे हल्के भोजन के साथ लिया जा सकता है। एंटासिड, आयरन, कैल्शियम, जिंक या मैग्नीशियम वाली दवाओं के साथ इसे न लें; इनके बीच कम से कम दो घंटे का अंतर रखें। धूप में बाहर जाते समय सनस्क्रीन और सुरक्षात्मक कपड़े पहनें। शराब न पिएं, क्योंकि इससे पेट और लिवर पर असर पड़ सकता है। अगर आपको किडनी या लिवर की बीमारी है, गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो डॉक्टर को पहले बताएं। कोर्स पूरा होने से पहले दवा बंद न करें, भले ही आप बेहतर महसूस करें।
💊 dobact dox 100 mg/100 mg tablet Uses & Benefits
[{"condition":"Dental and oral infections","description":"Used for gum infections, dental abscesses, and post-extraction inflammation where a tetracycline is appropriate and added anti-inflammatory support is desired.","evidence":"Commonly prescribed in dental practice"},{"condition":"Sinusitis and upper respiratory tract infections","description":"Prescribed for acute or chronic sinus infections when doxycycline is considered suitable and swelling of the lining needs to be reduced.","evidence":"Established for doxycycline; bromelain used as adjunct"},{"condition":"Skin and soft-tissue infections","description":"Used for acne-like eruptions, cellulitis, and wound infections caused by doxycycline-susceptible bacteria.","evidence":"Established for doxycycline"},{"condition":"Post-surgical swelling and pain","description":"Sometimes prescribed after minor oral or facial surgery to control infection and reduce swelling and discomfort.","evidence":"Limited for the combination"}]
Off-label uses: [{"condition":"Chronic inflammatory conditions","description":"Bromelain has been studied for its anti-inflammatory and anti-oedema effects in conditions such as arthritis and sports injuries, but this combination is not approved for these uses.","evidence":"Limited"},{"condition":"Rosacea","description":"Doxycycline at anti-inflammatory doses is sometimes used for rosacea, but the combination with bromelain is not standard for this indication.","evidence":"Limited"}]
Primary treatment for: Dental and oral infections with associated inflammation
Also treats: Sinusitis, Skin and soft-tissue infections, Post-surgical swelling and pain
📋 Drug Information
| Generic Name(s) | Doxycycline + Bromelain |
| Brand Name | Dobact Dox |
| Manufacturer | Tidal Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Tetracycline antibiotic + Proteolytic enzyme |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place. Keep the tablets in their original container, tightly closed, away from direct sunlight, heat, and moisture. Do not refrigerate unless the label specifically says so. Keep out of the reach of children and pets. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture, but you should always check the expiry date printed on the pack. Do not use the medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Doxycycline is a broad-spectrum tetracycline antibiotic that binds reversibly to the 30S ribosomal subunit of susceptible bacteria and blocks the attachment of aminoacyl-tRNA to the messenger RNA-ribosome complex. This stops the addition of new amino acids to the growing peptide chain and prevents bacterial protein synthesis, which halts bacterial growth and multiplication. Bromelain is a group of proteolytic enzymes that breaks down proteins and protein fragments. It is thought to reduce swelling and inflammation by modulating inflammatory mediators such as prostaglandins and bradykinin, and by promoting the breakdown of fibrin and other proteins that contribute to tissue swelling. Together, the antibiotic action of doxycycline and the anti-inflammatory action of bromelain are intended to address both infection and the associated swelling and pain.
Mechanism Steps
💡 How to Take dobact dox 100 mg/100 mg tablet
Strength: Each immediate-release oral tablet contains doxycycline 100 mg and bromelain 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken once or twice daily, depending on the infection being treated and your doctor's assessment. The dose and duration must be individualized by a qualified clinician based on the indication, age, weight, kidney and liver function, and response to treatment. Always swallow the tablet whole with a full glass of water, with or without food, and remain upright for at least thirty minutes. Do not change the dose or stop the course without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Doxycycline is generally avoided in children under eight years of age because it can cause permanent staining of developing teeth, except in specific situations where a specialist decides the benefit outweighs the risk. |
| Elderly Dosage | Older adults can usually take the same adult dose, but they are more likely to have reduced kidney or liver function and to be taking other medicines. Your doctor may adjust the dose or monitor you more closely, especially if you take blood thinners, antacids, or supplements. |
| Renal Impairment | Doxycycline is mainly excreted through bile and faeces, so dose reduction is usually not required in mild to moderate kidney impairment. In severe kidney impairment, your doctor may still choose to use it with caution and monitor you closely. Bromelain dose adjustment in kidney disease is not established from the available information. |
| Hepatic Impairment | Use with caution in liver disease. Your doctor may reduce the dose or avoid this medicine in severe liver impairment, and may monitor liver function tests during treatment. |
| Maximum Daily Dose | The maximum daily dose should not exceed what your doctor has prescribed. For doxycycline, the usual maximum adult dose is 200 mg per day for most indications, but higher doses may be used for specific infections under specialist supervision. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dobact dox 100 mg/100 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Isotretinoin | Major | |
| Antacids | Major | |
| Iron supplements | Major | |
| Calcium supplements | Major | |
| Methotrexate | Major | |
| Phenytoin | Moderate | |
| Carbamazepine | Moderate | |
| Rifampicin | Moderate | |
| Oral contraceptives | Moderate |
🚨 Major Interactions
- Warfarin and other anticoagulants
- Isotretinoin and other retinoids
- Antacids, iron, calcium, zinc, and magnesium salts
- Methotrexate
⚡ Moderate Interactions
- Phenytoin, carbamazepine, and rifampicin
- Oral contraceptives
- Penicillins and cephalosporins
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. It can worsen stomach irritation, increase the risk of liver strain, and may reduce your ability to follow the treatment plan properly. If you drink regularly, discuss this with your doctor before starting the course.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to doxycycline, other tetracyclines, bromelain, or pineapple","Children under eight years of age, except when specifically advised by a specialist","Pregnancy, especially after the fifteenth week, unless clearly needed","Severe liver disease","Systemic lupus erythematosus, because tetracyclines can worsen it"]
⚠️ Warnings & Precautions
["Take with a full glass of water and stay upright for at least thirty minutes to prevent food pipe irritation.","Avoid antacids, iron, calcium, zinc, and magnesium within two hours of this medicine.","Use sunscreen and protective clothing because of increased sun sensitivity.","Do not stop the course early even if you feel better.","Inform your doctor if you have kidney or liver disease, or if you are pregnant or breastfeeding.","Watch for severe diarrhoea, which may indicate a serious gut infection.","Avoid alcohol during treatment.","Do not share this medicine with others."]
🤱 Lactation Safety
Doxycycline passes into breast milk. Short courses are generally considered acceptable by many clinicians, but the safest approach is to discuss the risks and benefits with your doctor. Watch the baby for loose motions, thrush, or skin rash, and avoid prolonged use unless specifically advised.
💊 Overdose Management
Overdose of this medicine can cause severe nausea, vomiting, diarrhoea, and stomach pain. There is no specific antidote. Treatment is supportive and includes stopping the medicine, maintaining hydration, and monitoring for liver, kidney, and blood abnormalities. If you suspect an overdose, contact your doctor or a poison control centre immediately and go to the nearest emergency department. Do not try to induce vomiting unless a healthcare professional advises it.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, provided there is enough time before your next scheduled dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one. If you miss several doses, contact your doctor for advice.
Additional Safety Advice
Take this medicine exactly as your doctor has prescribed, with a full glass of water, and remain upright for at least thirty minutes after swallowing the tablet. Taking it with food or milk reduces stomach upset, but do not take it together with antacids, iron tablets, calcium supplements, or zinc, because these bind the doxycycline and stop it from working. Keep a gap of at least two hours before or after such products. Use a broad-spectrum sunscreen and protective clothing whenever you go outdoors, because this medicine makes your skin much more sensitive to sunlight. Do not stop the course early even if you feel better, as incomplete treatment can allow the infection to return and can encourage bacterial resistance. Avoid alcohol during treatment because it can worsen stomach irritation and liver stress. Tell your doctor if you have kidney or liver disease, if you are pregnant or planning pregnancy, or if you are breastfeeding. Do not share this medicine with anyone else, and keep it out of the reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to the side effects of this medicine, especially stomach upset, sun sensitivity, and interactions with other medicines. Kidney and liver function should be checked if there is any concern. The doctor may adjust the dose or choose a different antibiotic based on your overall health and other medicines.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss this medicine with your doctor before starting it. Doxycycline is generally avoided during pregnancy because it can affect the baby's developing teeth and bones. Your doctor may choose a different antibiotic that is safer for pregnancy. Use effective contraception during treatment if there is a risk of pregnancy.
🏥 Post-Surgery Considerations
This medicine is sometimes prescribed after minor oral or facial surgery to prevent infection and reduce swelling. Follow your surgeon's instructions carefully, including how long to take it and when to return for a follow-up. Report any increasing pain, swelling, fever, or discharge from the surgical site.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may be prescribed before or after dental work to prevent or treat infection. Continue taking it as prescribed unless your dentist or doctor tells you otherwise. Maintain good oral hygiene and follow post-procedure care instructions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild to moderate exercise is usually safe while taking this medicine. However, if you feel dizzy, weak, or have a fever, rest and avoid strenuous activity. Avoid outdoor exercise during peak sunlight hours because of increased sun sensitivity. If you have swelling or pain in a specific area, avoid activities that put stress on that part until it heals.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Most people can continue their usual work and daily activities while taking this medicine. If you feel dizzy, drowsy, or have blurred vision, avoid driving or operating heavy machinery until you feel normal. Take extra care with sun exposure if your work involves being outdoors. Keep your doctor informed if your symptoms interfere with your job or daily routine.
🛑 When to Stop This Medicine
Do not stop this medicine on your own, even if you feel better, because stopping early can allow the infection to return and can promote antibiotic resistance. Your doctor will tell you when to stop based on your condition and response to treatment. If you develop a serious side effect such as severe diarrhoea, a severe skin rash, or difficulty in breathing, stop the medicine and seek medical help immediately.
📅 Long-Term Use Effects
Long-term use of this medicine is not usually recommended unless a specialist advises it. Prolonged doxycycline use can increase the risk of antibiotic resistance, fungal overgrowth, sun sensitivity, and rarely liver or blood abnormalities. If long-term treatment is needed, your doctor may monitor your liver function, kidney function, and blood counts. Do not continue this medicine beyond the prescribed duration without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Regular brushing, flossing, and dental check-ups help prevent dental infections.
Evidence: Well-establishedCan help soothe throat and gum inflammation as an add-on to medical treatment.
Evidence: Traditionally usedApplying a cold pack to a swollen area can help reduce swelling and pain temporarily.
Evidence: Commonly usedMay help reduce antibiotic-associated stomach upset, but discuss with your doctor before starting.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not directly interact with most vaccines. However, if you have an active infection with fever, your doctor may advise delaying non-urgent vaccinations until you recover. Always inform the vaccination provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless the label specifically says so
✅ DO
Keep in the original container with the lid tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight, heat, and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of the reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription with you, especially when travelling internationally. Store it in a cool, dry place away from direct sunlight and do not leave it in a hot car. If you are crossing time zones, continue taking the tablet at the same interval as prescribed; your doctor can help you adjust the schedule if needed. Declare the medicine at customs if required and check the local rules about bringing prescription antibiotics into the country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within one to three days, but the full effect depends on the type and severity of the infection. Always complete the full course prescribed by your doctor.
A: Yes, you can take it with a light meal to reduce stomach upset. However, avoid taking it with a large glass of milk or with antacids, iron, calcium, zinc, or magnesium supplements within two hours.
A: Yes, doxycycline can make your skin more sensitive to sunlight. Use sunscreen and protective clothing when outdoors.
A: If you remember within half the dosing interval, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular schedule. Do not double dose.
A: Doxycycline is generally not recommended during pregnancy, especially after the fifteenth week, because it can affect the baby's teeth and bones. Inform your doctor if you are pregnant or planning pregnancy.
A: It is generally avoided in children under eight years of age because it can cause permanent tooth staining. A specialist may prescribe it in specific situations after weighing the benefits and risks.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be stopped as soon as you feel better.
Fact: You must complete the full course prescribed by your doctor to prevent the infection from returning and to reduce the risk of antibiotic resistance. - Myth: This medicine can be taken with milk or antacids without any problem.
Fact: Calcium, antacids, iron, and zinc reduce the absorption of doxycycline. Keep a gap of at least two hours. - Myth: This medicine is a painkiller for all types of pain.
Fact: It is an antibiotic with an anti-inflammatory enzyme. It does not relieve pain from causes other than the infection and inflammation it is prescribed for. - Myth: Bromelain in this medicine is just a vitamin.
Fact: Bromelain is a mixture of protein-digesting enzymes from pineapple that may help reduce swelling and inflammation.
🔄 Alternative Options
Generic Alternatives
- Doxycycline 100 mg + Bromelain 100 mg tablet
Brand Alternatives
- Dobact Dox 100 mg/100 mg tablet