diacer 50mg capsule

4.7 (16 reviews)

Diacerein (50mg)

🏭 Cadila Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is diacer 50mg capsule used for?

Artrodar 50mg Capsule (Diacerein) is used to treat PAIN ANALGESICS. It contains Diacerein (50mg), which Inhibits interleukin-1 beta (IL-1β) production and activity, thereby reducing c. Always consult your doctor before use. Take as prescribed.

Generic Name: Diacerein
Manufacturer: Cadila Pharmaceuticals Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 diacer 50mg capsule Uses & Benefits

Symptomatic treatment of osteoarthritis, particularly of the hip and knee.

Off-label uses: Rheumatoid arthritis (limited evidence), Ankylosing spondylitis

📋 Drug Information

Generic Name(s)	Diacerein
Brand Name	Artrodar 50mg Capsule
Manufacturer	Cadila Pharmaceuticals Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	Proteoglycan synthesis Stimulator
Route of Administration	Oral
Storage	Store at room temperature (15-30°C), protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed slowly after oral administration; peak plasma concentrations achieved in about 2-4 hours.

DistributionDistributes widely in tissues; crosses the blood-brain barrier to a limited extent.

Protein BindingApproximately 90% bound to plasma proteins, mainly albumin.

MetabolismExtensively metabolized in the liver via deacetylation to rhein, the active metabolite; also undergoes glucuronidation.

Half-LifeApproximately 7-8 hours for diacerein; rhein half-life is about 4-5 hours.

ExcretionExcreted primarily in urine (about 60%) as metabolites and unchanged drug; remainder in feces.

BioavailabilityAbout 35-56% due to first-pass metabolism.

Onset of ActionMay take 2-4 weeks for symptomatic relief.

Peak Plasma Time2-4 hours after oral administration.

Duration of ActionApproximately 24 hours; sustained effect with regular dosing.

How It Works

Inhibits interleukin-1 beta (IL-1β) production and activity, thereby reducing cartilage degradation and inflammation.

Mechanism Steps

1Inhibition of IL-1β production by chondrocytes and synovial cells

2Reduction of IL-1β-induced matrix metalloproteinase (MMP) expression

3Decreased degradation of proteoglycans and collagen in cartilage

💡 How to Take diacer 50mg capsule

Follow your doctor's prescription exactly.

⚠️ Side Effects of diacer 50mg capsule

✅ Common Side Effects

Diarrhea
Soft stools
Abdominal pain
Nausea
Headache

🚨 Serious Side Effects

Severe diarrhea leading to dehydration
Hepatotoxicity
Allergic reactions

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Toxic epidermal necrolysis
Angioedema

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Diuretics	Moderate	Reduced diuretic efficacy
NSAIDs	Moderate	Increased gastrointestinal side effects
Methotrexate	Moderate	Increased methotrexate toxicity
Antacids	Minor	Reduced absorption of diacerein
H2 receptor antagonists	Minor	Reduced absorption of diacerein

🚨 Major Interactions

Warfarin
Anticoagulants

⚡ Moderate Interactions

Diuretics
NSAIDs
Methotrexate

ℹ️ Minor Interactions

Antacids
H2 receptor antagonists

🍽️ Food Interactions

Food may delay absorption; take with or without food consistently.

🍷 Alcohol Interaction

Avoid alcohol as it may increase risk of hepatotoxicity.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to diacerein or any excipients; severe hepatic impairment; inflammatory bowel disease; pregnancy and lactation.

📊 Monitoring Parameters

Liver function tests, renal function, gastrointestinal symptoms.

🤱 Lactation Safety

Not recommended; excretion in breast milk unknown.

💊 Overdose Management

Induce vomiting or gastric lavage; symptomatic and supportive treatment.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for diacer 50mg capsule

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Alternative brands with exact same active ingredient (Diacerein (50mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

diacer 50mg capsule

What is diacer 50mg capsule used for?

💊 diacer 50mg capsule Uses & Benefits

📋 Drug Information

🔬 Pharmacology (PK/PD)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take diacer 50mg capsule

⚠️ Side Effects of diacer 50mg capsule

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

ℹ️ Minor Interactions

🍽️ Food Interactions

🍷 Alcohol Interaction

🛡️ Safety & Warnings

🚫 Contraindications

📊 Monitoring Parameters

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

🔄 Substitutes for diacer 50mg capsule

⭐ User Reviews

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