Agyl F 100mg/300mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Tingling or numbness in hands or feet
If experiencing severe symptoms, call emergency services immediately.
What is dezole mf 100 mg/300 mg tablet used for?
This medicine is a combination of furazolidone and metronidazole used to treat diarrhoea and dysentery caused by certain protozoa and bacteria. It works by killing the microorganisms responsible for the infection. It should be taken with food and alcohol must be avoided completely.
- Generic Name: Furazolidone (100mg) + Metronidazole (300mg)
- Manufacturer: Alde Medi Impex Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dezole mf 100 mg/300 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फ्यूराज़ोलिडोन और मेट्रोनिडाज़ोल का संयोजन है, जिसका उपयोग दस्त और पेचिश के इलाज के लिए किया जाता है। यह कुछ प्रोटोज़ोआ और बैक्टीरिया के कारण होने वाले संक्रमणों के खिलाफ प्रभावी है। यह दवा कीटाणुओं को मारकर काम करती है। इसे भोजन के साथ लेना चाहिए और इसके सेवन के दौरान शराब का सेवन पूरी तरह से बंद कर देना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, भूख न लगना, सिरदर्द और मुँह में धातु जैसा स्वाद शामिल हैं। कुछ लोगों का पेशाब गहरा या लाल-भूरा हो सकता है, जो हानिरहित और अस्थायी है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, तंत्रिका क्षति, रक्त विकार या शराब के साथ गंभीर प्रतिक्रिया हो सकती है। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। इस दवा के सेवन के दौरान और आखिरी खुराक के 48 घंटे बाद तक शराब का सेवन बिल्कुल न करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं या कोई अन्य दवा ले रही हैं, तो डॉक्टर को बताएं। दवा का पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें।
💊 dezole mf 100 mg/300 mg tablet Uses & Benefits
[{"condition":"Giardiasis","description":"This medicine is used to treat diarrhoea caused by Giardia lamblia infection.","evidence":"Well-established"},{"condition":"Amoebiasis","description":"This medicine is effective against Entamoeba histolytica, which causes amoebic dysentery.","evidence":"Well-established"},{"condition":"Bacterial diarrhoea","description":"This medicine may be used for certain bacterial causes of diarrhoea, but only when prescribed by a doctor.","evidence":"Limited"}]
Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Sometimes used as part of a combination regimen, but not a standard first-line option.","evidence":"Limited"}]
Primary treatment for: Diarrhoea and dysentery caused by susceptible protozoa and bacteria
Also treats: Giardiasis, Amoebiasis
📋 Drug Information
| Generic Name(s) | Furazolidone (100mg) + Metronidazole (300mg) |
| Brand Name | dezole mf 100 mg/300 mg tablet |
| Manufacturer | Alde Medi Impex Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep in the original container. |
| Shelf Life | Not established from the available information. Refer to the packaging for the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antimicrobial agents with different mechanisms. Furazolidone is a nitrofuran derivative that interferes with bacterial and protozoal enzyme systems, inhibiting essential metabolic processes and causing cell death. Metronidazole is a nitroimidazole that enters susceptible organisms and forms reactive intermediates that damage DNA, leading to cell death. Together, they provide broad coverage against certain protozoa and bacteria.
Mechanism Steps
💡 How to Take dezole mf 100 mg/300 mg tablet
Strength: Tablet containing Furazolidone 100 mg and Metronidazole 300 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally two to three times a day, or as prescribed by your doctor. The exact dose and duration depend on the type and severity of the infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate. Always follow your doctor's instructions. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use with caution and under medical supervision. Dose adjustment may be needed based on liver and kidney function. Consult your doctor. |
| Renal Impairment | Not established from the available information. Use with caution in patients with kidney disease. Dose adjustment may be needed. Consult your doctor. |
| Hepatic Impairment | Not established from the available information. Use with caution in patients with liver disease. Dose adjustment may be needed. Consult your doctor. |
| Maximum Daily Dose | Not established from the available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dezole mf 100 mg/300 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| MAO inhibitors | Major | |
| Cimetidine | Moderate | |
| Lithium | Moderate | |
| Tyramine-rich foods | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Alcohol
- Warfarin
- MAO inhibitors
⚡ Moderate Interactions
- Tyramine-rich foods
- Cimetidine
- Lithium
🍷 Alcohol Interaction
Alcohol must be strictly avoided while taking this medicine and for at least 48 hours after the last dose. Combining alcohol with this medicine can cause a disulfiram-like reaction, which includes severe nausea, vomiting, flushing, headache, and rapid heartbeat. In severe cases, it can lead to difficulty breathing and collapse. Inform your doctor if you consume alcohol regularly.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to furazolidone or metronidazole","Pregnancy, especially first trimester","Breastfeeding","Severe liver disease","Blood disorders such as low white blood cell count","Use of MAO inhibitors within the past 14 days","Alcohol consumption during treatment"]
⚠️ Warnings & Precautions
["Avoid alcohol completely during treatment and for 48 hours after.","Do not use for longer than prescribed to avoid nerve damage.","Use with caution in patients with liver or kidney disease.","May cause drowsiness or dizziness; avoid driving if affected.","Inform your doctor if you have a history of blood disorders.","Do not share this medicine with others.","Keep out of reach of children."]
🤱 Lactation Safety
This medicine passes into breast milk. It is not recommended during breastfeeding because it may cause harm to the nursing infant. Consult your doctor for alternative options.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, abdominal pain, and neurological symptoms. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Contact a poison control center or emergency department right away.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Swallow the tablet whole with a glass of water. Take it with food to reduce stomach upset. Avoid alcohol completely while taking this medicine and for at least 48 hours after finishing the course. Inform your doctor if you have liver disease, kidney disease, or any blood disorder before starting this medicine. Do not use this medicine for longer than prescribed, as prolonged use may increase the risk of nerve damage. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before taking this medicine. Keep this medicine out of reach of children. Store it in a cool, dry place away from direct sunlight. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, especially neurological effects and blood disorders. Use with caution and under medical supervision. Dose adjustment may be needed.
🤰 Pregnancy Planning (TTC)
This medicine should be avoided during pregnancy and while trying to conceive. Consult your doctor for alternative treatments if you are planning pregnancy.
🏥 Post-Surgery Considerations
Not established from the available information. Consult your doctor before taking this medicine after surgery.
🦷 Dental Procedures
Not established from the available information. Inform your dentist if you are taking this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel weak or dizzy. Light activity is fine if you feel up to it. Stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery if you are affected. Most people can continue their normal activities with caution.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Complete the full course as prescribed, even if you feel better. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of peripheral neuropathy and blood disorders. It should only be used for the prescribed duration. Regular monitoring may be needed if prolonged use is necessary. Consult your doctor if you have any concerns.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Essential for managing dehydration caused by diarrhoea.
Evidence: Well-establishedMay help restore gut flora, but not a replacement for antimicrobial therapy.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccinations if you are travelling to areas with high risk of infectious diarrhoea.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking it at the same intervals as prescribed. Check customs regulations for carrying prescription medicines. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 1-2 days, but it is important to complete the full course as prescribed.
A: Yes, take it with food to reduce stomach upset.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for dezole mf 100 mg/300 mg tablet
View AllAlternative brands with exact same active ingredient:
-
dependal m 100 mg/300 mg tabletGlaxo SmithKline Pharmaceuticals Ltd ₹4.85 7.5% COSTLIER
-
agyl f 100 mg/300 mg tabletAgron Remedies Pvt Ltd ₹5.50 22% COSTLIER
-
alfumet 100mg/300mg tabletAlbert David Ltd ₹5.71 26.6% COSTLIER
-
anaerid-f 100mg/300mg tabletMount Mettur Pharmaceuticals Ltd ₹7.17 59% COSTLIER
-
enterofuran m 100mg/300mg tabletDeys Medical ₹8.38 85.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of diarrhoea.
Fact: This medicine is only effective for specific protozoal and bacterial infections. It should not be used for viral diarrhoea or other causes. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed to prevent recurrence and resistance.