anaerid-f 100mg/300mg tablet - Furazolidone (100mg) + Metronidazole (300mg) medicine

Alfumet 100mg/300mg Tablet: Complete Medicine Guide

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🏭 Mount Mettur Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not recommended in pregnancy. Metronidazole crosses the placenta and furazolidone may pose risks. Use only if clearly needed and prescribed by a doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Yellowing of skin or eyes
  • Numbness or tingling in hands or feet
  • Seizures or confusion
  • Difficulty breathing or swelling of face, lips, or throat
  • Severe headache with visual changes

If experiencing severe symptoms, call emergency services immediately.

What is anaerid-f 100mg/300mg tablet used for?

This medicine is a combination of furazolidone and metronidazole used to treat certain gastrointestinal infections caused by protozoa and bacteria. It works by killing the infectious organisms. It must be taken exactly as prescribed, and alcohol must be avoided completely.

  • Generic Name: Furazolidone + Metronidazole
  • Manufacturer: Mount Mettur Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 anaerid-f 100mg/300mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा फ्यूराज़ोलिडोन और मेट्रोनिडाज़ोल का संयोजन है, जिसका उपयोग पेट और आंतों के कुछ संक्रमणों के इलाज के लिए किया जाता है। यह प्रोटोज़ोआ और बैक्टीरिया को मारकर काम करती है। इसे डॉक्टर के बताए अनुसार ही लें और शराब का सेवन बिल्कुल न करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में असहजता, मुँह में धातु जैसा स्वाद, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में हाथ-पैरों में झुनझुनी, दौरे, गंभीर एलर्जी और लीवर की समस्या हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। बीच में न छोड़ें, चाहे आप बेहतर महसूस करें। इलाज के दौरान और आखिरी खुराक के 48 घंटे बाद तक शराब का सेवन बिल्कुल न करें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। गर्भवती और स्तनपान कराने वाली महिलाएं इसका उपयोग न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 anaerid-f 100mg/300mg tablet Uses & Benefits

[{"condition":"Giardiasis","description":"This medicine is used to treat intestinal infection caused by Giardia lamblia, a common cause of diarrhoea and malabsorption.","evidence":"Well-established"},{"condition":"Amoebiasis","description":"It is effective against Entamoeba histolytica, which causes amoebic dysentery and liver abscess.","evidence":"Well-established"},{"condition":"Bacterial gastroenteritis","description":"It may be used for certain bacterial gut infections when susceptible organisms are involved.","evidence":"Limited"}]

Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Sometimes included in combination regimens for H. pylori, but not a first-line choice.","evidence":"Limited"}]

Primary treatment for: Gastrointestinal infections (giardiasis, amoebiasis)

Also treats: Bacterial gastroenteritis

📋 Drug Information

Generic Name(s)Furazolidone + Metronidazole
Brand NameAristogyl-F Oral Suspension
ManufacturerMount Mettur Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntibacterial, Antiprotozoal
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid alcohol completely during treatment and for 48 hours after the last dose.
3
Complete the full course as prescribed, even if you feel better.
4
Report any numbness, tingling, or weakness in hands or feet immediately.
5
Inform your doctor about all other medicines you are taking.
6
Use effective contraception during treatment if you are of childbearing age.
7
Do not breastfeed while taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic diarrhoea
This medicine is commonly prescribed for protozoal diarrhoea.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Abdominal cramps
May be prescribed if caused by susceptible organisms.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBoth furazolidone and metronidazole are absorbed from the gastrointestinal tract after oral administration. Furazolidone absorption is variable, while metronidazole is well absorbed.
DistributionMetronidazole distributes widely into body tissues and fluids, including cerebrospinal fluid, saliva, and breast milk. Furazolidone distribution is less well characterized.
Protein BindingMetronidazole is less than 20% bound to plasma proteins. Furazolidone protein binding is not well established.
MetabolismMetronidazole is metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C9 and CYP3A4, to hydroxy and acid metabolites. Furazolidone metabolism is not fully elucidated.
Half-LifeThe elimination half-life of metronidazole is approximately 6 to 8 hours in adults with normal renal and hepatic function. The half-life of furazolidone is not well established.
ExcretionMetronidazole and its metabolites are excreted primarily in urine, with some fecal excretion. Furazolidone is excreted partly in urine and bile.
BioavailabilityMetronidazole oral bioavailability is high, approximately 80% or more. Furazolidone bioavailability is not well established.
Onset of ActionThe onset of antimicrobial action depends on the infecting organism and the site of infection. Clinical improvement may be seen within 24 to 48 hours for susceptible infections.
Peak Plasma TimePeak plasma concentrations of metronidazole are reached within 1 to 2 hours after oral administration. Furazolidone peak time is not well established.
Duration of ActionThe duration of action depends on the dosing schedule and the half-life of the drugs. Metronidazole is usually dosed multiple times daily.

How It Works

This medicine combines two antimicrobial agents. Furazolidone is reduced by bacterial and protozoal enzymes to reactive intermediates that damage DNA and other macromolecules, leading to cell death. Metronidazole enters susceptible organisms and is reduced by ferredoxin-like electron transport proteins to nitro radical anions, which cause DNA strand breakage and inhibit nucleic acid synthesis. The combination provides broad coverage against certain protozoa and bacteria.

Mechanism Steps

1
Furazolidone activation: Furazolidone is reduced by microbial enzymes to reactive intermediates that damage DNA and proteins.
2
Metronidazole activation: Metronidazole is reduced by ferredoxin-like proteins in susceptible organisms to form reactive nitro radicals.
3
DNA damage: The reactive species cause DNA strand breaks and inhibit nucleic acid synthesis, leading to microbial death.

💡 How to Take anaerid-f 100mg/300mg tablet

Strength: Each tablet contains furazolidone 100 mg and metronidazole 300 mg.

1Take this medicine orally with a full glass of water.
2Take it with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Complete the full course even if you feel better.
6Avoid alcohol completely during treatment.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally two to three times daily, depending on the infection being treated. The exact dose and duration must be individualized by a qualified clinician based on the indication, severity of infection, age, weight, renal and hepatic function. Do not self-adjust the dose. Complete the full course as prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing.
Elderly DosageElderly patients may be more susceptible to side effects such as peripheral neuropathy and dizziness. Dose adjustment may be necessary based on renal and hepatic function. Use with caution and monitor closely.
Renal ImpairmentIn patients with severe renal impairment, metronidazole may accumulate. Dose adjustment may be required. Consult a doctor for individualized dosing.
Hepatic ImpairmentIn patients with severe hepatic impairment, dose reduction may be necessary due to reduced metabolism of metronidazole. Use with caution and monitor liver function.
Maximum Daily DoseThe maximum daily dose should not exceed the prescribed amount. Typically, the maximum is 3 tablets per day, but this must be determined by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Tyramine-rich foods (aged cheese, cured meats)
Avoid or limit
Furazolidone may cause hypertensive crisis.
Alcohol
Avoid completely
Can cause disulfiram-like reaction.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of anaerid-f 100mg/300mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Metallic taste (Common (5-10%))
Usually temporary. Chewing sugar-free gum may help.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Peripheral neuropathy (Rare (<0.1%))
Report numbness, tingling, or weakness in hands or feet immediately. May require stopping the medicine.
Seizures (Rare (<0.1%))
Seek emergency medical attention if seizures occur.
Severe allergic reaction (Rare (<0.1%))
Seek immediate medical help if you experience rash, swelling, or difficulty breathing.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain immediately.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate medical attention for severe upper abdominal pain radiating to back.
Optic neuritis
Report sudden vision changes or eye pain immediately.
Encephalopathy
Seek emergency care for confusion, disorientation, or severe headache.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Lithium Major
Phenytoin Moderate
Cimetidine Moderate

🚨 Major Interactions

  • Alcohol
  • Warfarin
  • Lithium

⚡ Moderate Interactions

  • Phenytoin
  • Cimetidine

🍷 Alcohol Interaction

Alcohol must be strictly avoided during treatment with this medicine and for at least 48 hours after the last dose. Concurrent use can cause a disulfiram-like reaction with flushing, severe nausea, vomiting, palpitations, and hypotension. It may also increase the risk of liver toxicity.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to furazolidone, metronidazole, or other nitroimidazoles/nitrofurans","Severe liver disease","Severe kidney disease","Pregnancy (especially first trimester)","Breastfeeding","Alcohol consumption during treatment","Use of disulfiram within past 2 weeks"]

⚠️ Warnings & Precautions

["Avoid alcohol completely during and for 48 hours after treatment.","May cause peripheral neuropathy with prolonged use; report numbness or tingling.","May cause seizures; use with caution in patients with seizure disorders.","Can cause disulfiram-like reaction with alcohol.","May interact with many drugs; inform your doctor about all medicines.","Not for use in viral infections.","Complete the full course as prescribed."]

🤱 Lactation Safety

Not recommended during breastfeeding. Metronidazole is excreted in breast milk and may affect the infant. Consult your doctor for alternatives.

💊 Overdose Management

Overdose may cause nausea, vomiting, dizziness, and potentially seizures or peripheral neuropathy. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if recent ingestion. Monitor vital signs and neurological status.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Avoid all alcohol-containing products during treatment and for at least 48 hours after the last dose. Inform your doctor about all other medicines you are taking, especially blood thinners, lithium, and anticonvulsants. Use effective contraception during treatment if you are of childbearing age. Do not breastfeed while taking this medicine. Report any unusual symptoms such as numbness, tingling, or mood changes immediately. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to peripheral neuropathy, dizziness, and liver toxicity. Use with caution and monitor closely. Dose adjustment may be needed based on renal and hepatic function.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for alternative treatments. Use effective contraception during treatment.

🏥 Post-Surgery Considerations

Consult your surgeon before taking this medicine after surgery, as it may interact with other medications and affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with certain dental medications and increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hand hygiene to prevent reinfection.
🥗
Drink safe, clean water.
😴
Avoid raw or undercooked foods.
💧
Get adequate rest to support recovery.
🧘
Stay hydrated with oral rehydration solutions if you have diarrhoea.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or weak. Light activity is fine if you feel well. Stay hydrated.

🥗 Diet Recommendations

Eat bland, easily digestible foods like rice, bananas, and toast.
Avoid spicy, oily, and processed foods.
Stay well hydrated.
Avoid alcohol and caffeine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. Take rest as needed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full prescribed course. If you experience serious side effects, contact your doctor immediately; they may advise stopping.

📅 Long-Term Use Effects

Prolonged use may increase the risk of peripheral neuropathy, liver toxicity, and blood disorders. Regular monitoring of liver function, renal function, and neurological symptoms is advised for long-term therapy. Use the shortest effective duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral rehydration therapy

Helps manage dehydration from diarrhoea.

Evidence: Well-established
Probiotics

May help restore gut flora during and after infection.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If traveling across time zones, adjust dosing times gradually under medical advice. Avoid alcohol during travel. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with persistent diarrhoea and abdominal cramps
He was diagnosed with giardiasis and prescribed this medicine. He took it with food as directed and avoided alcohol completely. His symptoms improved within 3 days, and he completed the full 7-day course. He reported mild nausea initially, which subsided after taking it with meals.
💡 Lesson: Taking the medicine with food reduces nausea, and completing the full course prevents recurrence.
👤 A 50-year-old woman with amoebic dysentery
She was prescribed this medicine for amoebiasis. She experienced a metallic taste and mild dizziness, but these were temporary. She was advised to avoid alcohol and did so. Her infection resolved completely after the prescribed course.
💡 Lesson: Temporary side effects like metallic taste and dizziness are common but usually resolve. Adherence to the full course is crucial.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvement in symptoms may be seen within 24 to 48 hours, but you must complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, taking it with food helps reduce stomach upset and nausea.

Q: What should I avoid while taking this medicine?

A: Avoid alcohol completely and limit tyramine-rich foods. Inform your doctor about all other medicines.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for anaerid-f 100mg/300mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any stomach infection.
    Fact: It is only effective against specific susceptible organisms and should not be used for viral or other infections.
  • Myth: You can stop taking it once you feel better.
    Fact: You must complete the full course to prevent recurrence and resistance.

📊 Comparison with Similar Medicines

[{"medicine":"Metronidazole alone","difference":"Lacks furazolidone; may be less effective for certain infections."},{"medicine":"Tinidazole","difference":"Longer half-life, different dosing schedule."}]

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