Aspirose 10mg/75mg Capsule: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unexplained muscle pain with dark urine
If experiencing severe symptoms, call emergency services immediately.
What is aspirose 10mg/75mg capsule used for?
This medicine is a combination of Rosuvastatin 10 mg and Aspirin 75 mg used to lower cholesterol and prevent blood clots in patients at high risk of heart attack or stroke. It is taken orally once daily with food. It should not be used in pregnancy, active bleeding, or severe liver disease.
- Generic Name: Rosuvastatin (10mg) + Aspirin (75mg)
- Manufacturer: Alde Medi Impex Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aspirose 10mg/75mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा रोसुवास्टेटिन 10 मिलीग्राम और एस्पिरिन 75 मिलीग्राम का संयोजन है। इसका उपयोग कोलेस्ट्रॉल कम करने और रक्त के थक्के बनने से रोकने के लिए किया जाता है, जिससे दिल का दौरा और स्ट्रोक का खतरा कम होता है। यह उन रोगियों के लिए निर्धारित की जाती है जिन्हें हृदय रोग या उच्च कोलेस्ट्रॉल है। इसे भोजन के साथ मुँह से लिया जाता है। गर्भावस्था, सक्रिय रक्तस्राव, या गंभीर यकृत रोग में इसका उपयोग नहीं करना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में पेट में जलन, मतली, सिरदर्द, मांसपेशियों में दर्द, और आसानी से चोट लगना या खून बहना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों से खून बहना, एलर्जी, यकृत की समस्या, और मांसपेशियों का टूटना शामिल हो सकता है। यदि काला या खून वाला मल, खून की उल्टी, गंभीर पेट दर्द, या मांसपेशियों में असहनीय दर्द हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे रक्तस्राव और यकृत की समस्या का खतरा बढ़ता है। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। नियमित रूप से लिवर और किडनी की जांच कराएं। सर्जरी या दंत चिकित्सा से पहले डॉक्टर को इस दवा के बारे में बताएं। डॉक्टर की सलाह के बिना दवा बंद न करें।
💊 aspirose 10mg/75mg capsule Uses & Benefits
[{"condition":"Primary hypercholesterolemia","description":"Used to reduce elevated LDL cholesterol and triglycerides in patients with high cholesterol not controlled by diet and exercise alone.","evidence":"Well-established"},{"condition":"Secondary prevention of cardiovascular events","description":"Reduces the risk of heart attack, stroke, and cardiovascular death in patients with established cardiovascular disease.","evidence":"Well-established"},{"condition":"Mixed dyslipidemia","description":"Helps manage combined high cholesterol and high triglycerides.","evidence":"Well-established"},{"condition":"Prevention of thrombosis in high-risk patients","description":"Low-dose aspirin reduces platelet aggregation and clot formation in patients at high risk of arterial thrombosis.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of preeclampsia","description":"Low-dose aspirin is sometimes used off-label in pregnancy to reduce the risk of preeclampsia in high-risk women, but this combination with rosuvastatin is not recommended in pregnancy.","evidence":"Limited"},{"condition":"Colorectal cancer prevention","description":"Aspirin has been studied for chemoprevention of colorectal cancer, but this combination is not approved for this use.","evidence":"Limited"}]
Primary treatment for: Cardiovascular disease prevention and hypercholesterolemia
Also treats: Atherosclerosis, Coronary artery disease, Stroke prevention, Peripheral artery disease
📋 Drug Information
| Generic Name(s) | Rosuvastatin (10mg) + Aspirin (75mg) |
| Brand Name | aspirose 10mg/75mg capsule |
| Manufacturer | Alde Medi Impex Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place away from direct sunlight. Keep the container tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. Guidelines from various cardiology societies recommend statins and antiplatelet therapy for secondary prevention, but this specific combination is not directly referenced. |
| ICMR Guideline | Not established from the available information. ICMR guidelines recommend statins and aspirin for secondary prevention of cardiovascular disease, but this specific combination is not directly referenced. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Rosuvastatin selectively and competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis. This inhibition leads to upregulation of LDL receptors on hepatocytes, increasing clearance of LDL cholesterol from the blood and reducing plasma LDL levels. Aspirin acetylates serine residue 529 of cyclooxygenase-1 (COX-1) in platelets, irreversibly inhibiting the enzyme. This prevents the conversion of arachidonic acid to prostaglandin H2, thereby reducing thromboxane A2 synthesis. Thromboxane A2 is a potent vasoconstrictor and platelet aggregator; its reduction decreases platelet aggregation and clot formation.
Mechanism Steps
💡 How to Take aspirose 10mg/75mg capsule
Strength: Capsule containing Rosuvastatin 10 mg and Aspirin 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule (Rosuvastatin 10 mg + Aspirin 75 mg) taken orally once daily, preferably with food. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and other medications. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially increased bleeding risk and muscle side effects. Dose should be individualized by a clinician. Regular monitoring of kidney and liver function is advised. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is usually needed. In severe renal impairment (creatinine clearance <30 mL/min), rosuvastatin should be used with caution and the dose should be individualized by a clinician. Aspirin should be avoided in severe renal impairment due to increased risk of bleeding and worsening kidney function. |
| Hepatic Impairment | This medicine is contraindicated in patients with active liver disease or unexplained persistent elevations of liver enzymes. In patients with mild to moderate hepatic impairment, dose should be individualized by a clinician. Rosuvastatin should be used with caution. |
| Maximum Daily Dose | The maximum recommended daily dose for this specific combination is one capsule (Rosuvastatin 10 mg + Aspirin 75 mg). Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aspirose 10mg/75mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Cyclosporine | Major | |
| Gemfibrozil | Major | |
| Clopidogrel | Moderate | |
| Methotrexate | Moderate | |
| ACE inhibitors | Moderate | |
| Furosemide | Moderate | |
| Antacids | Moderate | |
| Cimetidine | Minor |
🚨 Major Interactions
- Warfarin
- Other anticoagulants (e.g., apixaban, rivaroxaban)
- NSAIDs (e.g., ibuprofen, naproxen)
- Cyclosporine
- Gemfibrozil
⚡ Moderate Interactions
- Clopidogrel
- Methotrexate
- ACE inhibitors
- Furosemide
- Antacids
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding due to aspirin and can worsen liver toxicity from rosuvastatin. It may also increase the risk of muscle-related side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active bleeding or bleeding disorders (e.g., hemophilia).","Active peptic ulcer disease.","Severe liver disease or unexplained persistent elevations of liver enzymes.","Aspirin-sensitive asthma or history of allergic reaction to aspirin or NSAIDs.","Pregnancy, especially third trimester.","Breastfeeding.","Children and adolescents under 18 years.","Concurrent use with cyclosporine or gemfibrozil."]
⚠️ Warnings & Precautions
["Increased risk of gastrointestinal bleeding: take with food and report any signs of bleeding.","Risk of muscle injury (myopathy, rhabdomyolysis): report unexplained muscle pain, weakness, or dark urine.","Liver enzyme elevations: monitor liver function regularly.","Kidney function impairment: use with caution in renal impairment.","Avoid alcohol: increases risk of bleeding and liver toxicity.","Do not use in children or adolescents.","Inform your doctor if you are scheduled for surgery or dental procedures.","May cause prolonged bleeding time: inform healthcare providers before any procedure.","Not for use in pregnancy or breastfeeding.","Do not stop abruptly without medical advice."]
🤱 Lactation Safety
Not established from the available information. Rosuvastatin and aspirin may pass into breast milk. This medicine is not recommended during breastfeeding. Consult your doctor for safe alternatives.
💊 Overdose Management
Overdose may cause symptoms such as severe gastrointestinal bleeding, ringing in the ears, rapid breathing, confusion, or muscle pain. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote for rosuvastatin; aspirin overdose may be treated with activated charcoal, gastric lavage, and supportive care. Hemodialysis may be considered for severe salicylate toxicity.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the capsule; swallow it whole with a glass of water. It is best taken with food to reduce stomach upset. Avoid alcohol consumption as it can increase the risk of gastrointestinal bleeding and liver problems. Inform your doctor about all other medicines, especially blood thinners, NSAIDs, and other cholesterol-lowering drugs. Do not start any new medicine without consulting your doctor. Regular monitoring of liver function, kidney function, and lipid profile is recommended. If you are scheduled for surgery or dental procedures, inform your healthcare provider about this medicine. Do not stop taking this medicine abruptly without medical advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially increased bleeding risk and muscle side effects. Dose should be individualized by a clinician. Regular monitoring of kidney and liver function is advised.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine before any surgery. It may need to be stopped several days before surgery due to increased bleeding risk. Do not stop without medical advice.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. It may increase bleeding during dental work. Your dentist may recommend stopping it temporarily or taking precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is beneficial, but avoid strenuous activities that may increase the risk of bleeding or injury, especially if you are prone to bruising. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or unusual bleeding, avoid such activities and consult your doctor. It is important to take the medicine at the same time each day, which may require adjusting your routine.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe bleeding, muscle pain with dark urine, or signs of liver injury, seek immediate medical attention. Your doctor may adjust the dose or switch to an alternative medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may require regular monitoring of liver function, kidney function, and lipid profile. Prolonged aspirin use can increase the risk of gastrointestinal bleeding and ulcers. Rosuvastatin may rarely cause muscle injury or liver enzyme elevation. Regular follow-up with your doctor is essential to adjust the dose and monitor for side effects.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise can help manage cholesterol and cardiovascular risk.
Evidence: Well-establishedAtorvastatin or simvastatin may be used as alternatives to rosuvastatin.
Evidence: Well-establishedClopidogrel may be used if aspirin is not tolerated.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, inform your healthcare provider about this medicine before receiving any vaccine. Live vaccines should be avoided if you are on immunosuppressive therapy, but this medicine is not immunosuppressive.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from direct sunlight. If traveling across time zones, continue taking your dose at the same time each day as prescribed. Check customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Rosuvastatin starts lowering cholesterol within 1-2 weeks, with maximum effect in 4-6 weeks. Aspirin's antiplatelet effect begins within 30-60 minutes.
A: Some medications can interact. Always inform your doctor about all medicines you are taking, especially blood thinners, NSAIDs, and other cholesterol-lowering drugs.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is not recommended during pregnancy, especially in the third trimester. Consult your doctor for alternative treatments.
A: Do not stop taking this medicine without consulting your doctor. Stopping abruptly can increase your risk of heart attack or stroke.
🤔 Common Patient Concerns
🔄 Substitutes for aspirose 10mg/75mg capsule
View AllAlternative brands with exact same active ingredient:
-
davaindia rosuvastatin+aspirin 10mg/75mg capsuleDavaindia Generic Pharmacy ₹25.00 55.6% CHEAPER
-
danavish rosuvastatin+aspirin 10mg/75mg capsuleDanavish Healthcare ₹31.88 43.3% CHEAPER
-
rosprin 10mg/75mg capsuleFiner Pharmaceuticals Pvt Ltd ₹39.38 30% CHEAPER
-
davaindia aspirin+rosuvastatin+clopidogrel 75mg/10mg/75mg capsuleDavaindia Generic Pharmacy ₹41.80 25.7% CHEAPER
-
r10a 10 mg/75 mg capsuleCentaur Pharmaceuticals Pvt Ltd ₹42.03 25.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: It is safe to take this medicine with alcohol.
Fact: Alcohol increases the risk of bleeding and liver problems; it should be avoided. - Myth: This medicine can be taken during pregnancy.
Fact: This medicine is not recommended during pregnancy, especially in the third trimester. - Myth: You can stop taking this medicine once cholesterol levels normalize.
Fact: Cholesterol levels may rise again if the medicine is stopped. Consult your doctor before stopping.
🔄 Alternative Options
Generic Alternatives
- Rosuvastatin 10 mg + Aspirin 75 mg capsule (generic)
Brand Alternatives
- Aspirose 10mg/75mg capsule