cromide 5mg/2.5mg tablet - Uses, Price, Side Effects & Substitutes
What is cromide 5mg/2.5mg tablet used for?
Aurinorm 5 mg/2.5 mg tablet (Chlordiazepoxide + Clidinium) is used to treat GASTRO INTESTINAL. It contains Chlordiazepoxide (5mg) + Clidinium (2.5mg), which Chlordiazepoxide enhances GABA-A receptor activity; Clidinium blocks muscarinic . Always consult your doctor before use. Take as prescribed.
- Generic Name: Chlordiazepoxide + Clidinium
- Manufacturer: Leeford Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cromide 5mg/2.5mg tablet Uses & Benefits
Irritable bowel syndrome, peptic ulcer disease, anxiety with gastrointestinal symptoms
Off-label uses: Gastrointestinal motility disorders, functional dyspepsia
๐ Drug Information
| Generic Name(s) | Chlordiazepoxide + Clidinium |
| Brand Name | Aurinorm 5 mg/2.5 mg tablet |
| Manufacturer | Leeford Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Benzodiazepine + Anticholinergic |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Chlordiazepoxide enhances GABA-A receptor activity; Clidinium blocks muscarinic acetylcholine receptors
Mechanism Steps
๐ก How to Take cromide 5mg/2.5mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cromide 5mg/2.5mg tablet
โ Common Side Effects
- Drowsiness
- Dizziness
- Dry mouth
- Blurred vision
- Constipation
๐จ Serious Side Effects
- Respiratory depression
- Severe sedation
- Paradoxical reactions
- Dependence
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Jaundice
- Hypersensitivity reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | Increased sedation and respiratory depression |
| Opioid analgesics | Major | Additive CNS depression |
| MAO inhibitors | Major | Increased anticholinergic effects |
| Cimetidine | Moderate | Increased chlordiazepoxide levels |
| Antacids | Moderate | Decreased absorption of chlordiazepoxide |
| Oral contraceptives | Moderate | Increased chlordiazepoxide levels |
| Grapefruit juice | Minor | Increased chlordiazepoxide levels |
| Caffeine | Minor | Reduced sedative effect |
| Smoking | Minor | Decreased chlordiazepoxide levels |
๐จ Major Interactions
- CNS depressants
- MAO inhibitors
- Opioid analgesics
โก Moderate Interactions
- Antacids
- Cimetidine
- Oral contraceptives
โน๏ธ Minor Interactions
- Caffeine
- Smoking
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase chlordiazepoxide levels
๐ท Alcohol Interaction
Enhanced CNS depression; avoid concurrent use
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, narrow-angle glaucoma, myasthenia gravis, severe hepatic impairment, pregnancy
๐ Monitoring Parameters
Liver function, renal function, CNS depression, anticholinergic effects
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Supportive care; flumazenil for chlordiazepoxide; physostigmine for clidinium (if severe anticholinergic symptoms)
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double