Ascoril C Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Slow, shallow, or difficult breathing
- Severe drowsiness, confusion, or difficulty waking up
- Swelling of the face, lips, tongue, or throat
- Severe dizziness or fainting
- Severe abdominal pain, vomiting, or inability to pass stool
- Unusual bruising or bleeding
- Yellowing of the eyes or skin, or dark urine
- Seizure or loss of consciousness
If experiencing severe symptoms, call emergency services immediately.
What is cozin syrup used for?
This medicine is a prescription cough syrup that combines chlorpheniramine maleate, an antihistamine, with codeine, an opioid cough suppressant. It is used for short-term relief of dry, irritating cough, especially when allergy symptoms are also present. It can cause drowsiness and must not be used in children below 12 years or with alcohol.
- Generic Name: Chlorpheniramine Maleate + Codeine
- Manufacturer: Somatico Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cozin syrup के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से सूखी, चुभने वाली और लगातार होने वाली खांसी के लिए इस्तेमाल की जाती है, खासकर जब खांसी के साथ छींक, नाक बहना और गले में खराश जैसी एलर्जी की समस्याएं भी हों। इसमें क्लोरफेनिरामिन मेलिएट नामक एंटीहिस्टामिन और कोडीन नामक खांसी को दबाने वाला ओपिओइड होता है। यह दवा खांसी की तीव्रता और बार-बार आने वाले खांसी के दौरों को कम करने में मदद करती है, लेकिन यह खांसी की जड़ का इलाज नहीं करती। यह केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और 12 साल से छोटे बच्चों को नहीं देनी चाहिए। इस दवा से नींद आ सकती है, इसलिए गाड़ी चलाने या मशीन चलाने से बचें और शराब बिल्कुल न लें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधला दिखना, जी मिचलाना, उल्टी, कब्ज और पेशाब करने में कठिनाई शामिल हैं। कुछ लोगों को बहुत ज्यादा थकान, भ्रम या अस्थिरता महसूस हो सकती है। गंभीर लेकिन कम होने वाले दुष्प्रभावों में सांस धीमी या उथली होना, तेज कब्ज, पेट दर्द, एलर्जी जैसे दाने या सूजन, और मानसिक बदलाव जैसे बेचैनी या मूड में उतार-चढ़ाव शामिल हैं। कोडीन की लत लग सकती है, इसलिए डॉक्टर की सलाह के बिना लंबे समय तक इसका सेवन न करें। अगर कोई भी दुष्प्रभाव गंभीर या लगातार बना रहे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा न बढ़ाएं और न ही ज्यादा बार लें। शराब और नींद लाने वाली दवाओं जैसे नींद की गोलियां, चिंता की दवाएं, मांसपेशियों को आराम देने वाली दवाएं और अन्य एंटीहिस्टामिन के साथ इसका सेवन न करें, जब तक डॉक्टर मना न करें। जब तक पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक गाड़ी न चलाएं और मशीन न चलाएं। बच्चों की पहुंच से दूर रखें। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। सांस लेने में तकलीफ, गंभीर चक्कर, बेहोशी या एलर्जी के लक्षण दिखने पर दवा बंद करें और तुरंत डॉक्टर से मिलें। यह दवा किसी और के साथ साझा न करें।
💊 cozin syrup Uses & Benefits
[{"condition":"Dry, irritating cough associated with allergy or common cold","description":"This medicine is used for short-term relief of a non-productive cough that is dry, tickly, and bothersome, especially when allergy symptoms such as sneezing and runny nose are also present.","evidence":"Established for short-term symptomatic relief when prescribed"},{"condition":"Cough with allergic rhinitis symptoms","description":"The antihistamine component helps reduce sneezing, runny nose, and throat irritation, while the codeine component reduces the cough reflex.","evidence":"Established for short-term use"},{"condition":"Night-time cough disturbing sleep","description":"Because this medicine can cause drowsiness, it is sometimes prescribed for short-term relief of cough that is interfering with sleep, but only under medical supervision.","evidence":"Limited to short-term, clinician-directed use"}]
Off-label uses: [{"condition":"Allergic cough in selected adults","description":"Sometimes used for short-term relief of cough clearly linked to allergy when other treatments are not suitable, but this must be decided by a clinician.","evidence":"Limited"}]
Primary treatment for: Dry, irritating cough associated with allergy or common cold
Also treats: Allergic rhinitis with cough, Night-time cough disturbing sleep, Cough with throat irritation
📋 Drug Information
| Generic Name(s) | Chlorpheniramine Maleate + Codeine |
| Brand Name | Ascoril C Syrup |
| Manufacturer | Somatico Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antitussive and Antihistamine Combination |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the bottle tightly closed and out of reach of children. Do not freeze unless the label specifically says it is safe to do so. |
| Shelf Life | Not established from the available information. Check the expiry date printed on the pack and do not use after that date. |
| WHO Guideline | Not established from the available information. Codeine-containing cough syrups are not recommended for children below 12 years by many regulatory authorities, and their use should follow local prescribing guidelines. |
| ICMR Guideline | Not established from the available information. Follow the advice of your treating doctor and local guidelines. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary actions. Chlorpheniramine maleate is a first-generation antihistamine that blocks histamine H1 receptors, reducing allergy symptoms such as sneezing, runny nose, and throat irritation. Codeine is an opioid antitussive that acts on the cough center in the brain to suppress the cough reflex. Together, they reduce cough frequency and allergy-related throat irritation, but they do not treat the underlying infection or allergy.
Mechanism Steps
💡 How to Take cozin syrup
Strength: Each 5 mL of syrup contains chlorpheniramine maleate 4 mg and codeine 10 mg, as per the product composition. The exact strength and volume may vary by pack; always check the label.
Dosage Information
| Adult Dosage | The usual adult dose is prescribed by a doctor based on the severity of cough, age, weight, kidney function, liver function, and other medicines being taken. A common adult schedule is one teaspoonful or the prescribed amount every 4 to 6 hours as needed, but the exact dose and frequency must be individualized by a qualified clinician. Do not exceed the prescribed dose. Do not use for longer than the doctor advises. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children below 12 years of age. |
| Elderly Dosage | Older adults are more sensitive to the sedative and anticholinergic effects of this medicine. They may need a lower dose or a different medicine, and they should be monitored closely for drowsiness, confusion, dizziness, constipation, and difficulty passing urine. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Not established from the available information. Both ingredients are excreted mainly by the kidneys, so people with kidney disease may need a lower dose or a different medicine. A doctor should decide the dose after checking kidney function. |
| Hepatic Impairment | Not established from the available information. Both ingredients are processed by the liver, so people with liver disease may need a lower dose or a different medicine. A doctor should decide the dose after checking liver function. |
| Maximum Daily Dose | Not established from the available information. Do not exceed the dose prescribed by your doctor. The maximum daily dose depends on age, weight, kidney and liver function, and other medicines being taken. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cozin syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Other opioids | Major | |
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Tricyclic antidepressants | Moderate | |
| Muscle relaxants | Moderate | |
| CYP2D6 inhibitors | Moderate | |
| Antihistamines | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Other opioid medicines
- Alcohol
- Benzodiazepines and other sedatives
⚡ Moderate Interactions
- Antihistamines and cold medicines
- Tricyclic antidepressants
- Muscle relaxants
- CYP2D6 inhibitors such as fluoxetine and paroxetine
🍷 Alcohol Interaction
Alcohol must be avoided while taking this medicine. Alcohol increases drowsiness, dizziness, and the risk of slow or shallow breathing because both codeine and chlorpheniramine maleate add to the sedative effect. Combining alcohol with this medicine can also impair judgment and reaction time, making driving or operating machinery dangerous.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Children below 12 years of age","Known allergy to chlorpheniramine maleate, codeine, or any ingredient","Severe asthma or other breathing problems with respiratory depression","Paralytic ileus or severe bowel obstruction","Use with monoamine oxidase inhibitors or within 14 days of stopping them","Breastfeeding unless specifically approved by a doctor","Severe liver or kidney disease unless a doctor approves"]
⚠️ Warnings & Precautions
["This medicine can cause drowsiness; avoid driving and operating machinery until you know how it affects you.","Do not drink alcohol while taking this medicine.","Do not take other sedating medicines without your doctor's approval.","Codeine can be habit-forming; use only for the shortest time prescribed.","Do not give this medicine to children below 12 years.","Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Tell your doctor about all medicines, supplements, and herbal products you take.","Stop and seek medical help if you have trouble breathing, severe dizziness, or signs of an allergic reaction."]
🤱 Lactation Safety
Not established from the available information. Codeine can pass into breast milk and may cause serious breathing problems in a breastfed baby. Breastfeeding is generally not recommended while taking this medicine unless a doctor specifically approves it.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, slow or shallow breathing, cold and clammy skin, slow heartbeat, confusion, and loss of consciousness. This is a medical emergency. Call emergency services immediately and go to the nearest hospital. Do not try to make the person vomit unless instructed by a medical professional. If available, tell the medical team the exact amount taken and the time it was taken. Treatment may include supportive care, monitoring of breathing, and use of an antidote such as naloxone for opioid effects, given by trained medical staff.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than directed. Avoid alcohol and other medicines that make you sleepy, such as sleeping pills, anxiety medicines, muscle relaxants, and other antihistamines, unless your doctor approves. Do not drive, ride a bicycle, or operate heavy machinery until you know how this medicine affects your alertness. Keep out of reach of children. Do not use this medicine for a cough that produces a lot of mucus unless your doctor specifically advises it. Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. Tell your doctor about all other medicines, supplements, and herbal products you take. Stop the medicine and seek medical help if you have trouble breathing, severe dizziness, fainting, or signs of an allergic reaction. Do not share this medicine with anyone else, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to experience drowsiness, confusion, dizziness, constipation, and difficulty passing urine with this medicine. They may also be more sensitive to breathing problems. Use with caution, consider a lower dose, and monitor closely. Falls are a particular risk because of dizziness and unsteadiness.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, talk to your doctor before taking this medicine. Codeine and chlorpheniramine maleate should be used during pregnancy only when clearly needed and prescribed by a doctor. Prolonged use near term can cause problems in the newborn. Discuss safer alternatives for cough relief.
🏥 Post-Surgery Considerations
Not established from the available information. After surgery, this medicine should be used only if prescribed by your surgeon or doctor, because it can add to the sedative effects of anesthesia and pain medicines and may increase the risk of breathing problems.
🦷 Dental Procedures
Tell your dentist if you are taking this medicine before any dental procedure. It can cause dry mouth and drowsiness, and it may interact with sedatives or pain medicines used during dental work. Your dentist may advise adjusting the dose or timing.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that require full alertness while taking this medicine because it can cause drowsiness and dizziness. Light activity such as walking is usually fine if you feel well, but stop and rest if you feel dizzy or short of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and reduced alertness, which may affect your ability to drive, operate machinery, or perform tasks that require concentration. Avoid driving or risky activities until you know how the medicine affects you. If your work requires alertness, discuss with your doctor about timing the dose or choosing an alternative.
🛑 When to Stop This Medicine
Stop this medicine when your doctor advises, usually after a few days when the cough improves. Do not stop suddenly if you have been taking it for a long time without talking to your doctor, because withdrawal symptoms may occur. Seek medical help if you develop breathing difficulty, severe drowsiness, or signs of an allergic reaction.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of codeine can lead to tolerance, dependence, and withdrawal symptoms when stopped suddenly. Chlorpheniramine maleate can cause persistent drowsiness, dry mouth, constipation, and urinary problems, especially in older adults. If this medicine is needed for more than a few days, a doctor should reassess the cause of the cough and consider safer alternatives. Regular monitoring of alertness, bowel habits, and breathing is important during prolonged use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help soothe throat irritation and loosen secretions.
Evidence: Supportive careMay help soothe the throat and reduce cough in some people.
Evidence: Limited but commonly usedDextromethorphan or other non-opioid options may be safer for some patients.
Evidence: Established for selected patientsAllergy treatment, infection management, or asthma control may reduce cough more effectively.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There is no known direct interaction between this medicine and vaccines. If you are due for a vaccine, tell your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not store in extreme heat or direct sunlight
✅ DO
Keep the bottle tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription copy. Keep it in your hand luggage if you need it during travel, and store it at room temperature away from direct sunlight and moisture. If you are crossing time zones, follow your doctor's advice on timing; do not take extra doses to adjust. Check the customs rules of your destination country because codeine-containing medicines may be controlled or restricted. Do not leave the medicine in a hot car or in checked luggage where it may be exposed to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Cough suppression and antihistamine effects usually begin within 30 to 60 minutes after taking the syrup, but this can vary from person to person.
A: This medicine is meant for short-term use only. Do not take it for longer than your doctor advises because codeine can be habit-forming and long-term use can cause other problems.
A: Do not take other cough syrups or antihistamines without your doctor's approval, as this can increase drowsiness and other side effects.
A: Avoid driving or operating machinery and contact your doctor. A lower dose or a different medicine may be needed.
A: This medicine is not recommended for children below 12 years because of the risk of serious breathing problems. Consult a pediatrician for safe alternatives.
🤔 Common Patient Concerns
🔄 Substitutes for cozin syrup
View AllAlternative brands with exact same active ingredient:
-
codex 4 mg/10 mg expectorantConcept Pharmaceuticals Ltd ₹14.06 75.8% CHEAPER
-
cirocod 4mg/10mg linctusCiron Drugs & Pharmaceuticals Pvt Ltd ₹20.00 65.5% CHEAPER
-
respinex cd 4 mg/10 mg syrupAlembic Pharmaceuticals Ltd ₹24.38 58% CHEAPER
-
kodekof syrupFinecure Pharmaceuticals Ltd. ₹26.00 55.2% CHEAPER
-
cofrex syrupTunic Healthcare ₹26.06 55.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any type of cough.
Fact: This medicine is meant for dry, irritating cough and is not suitable for cough with a lot of mucus unless a doctor advises it. - Myth: More syrup means faster relief.
Fact: Taking more than prescribed can cause serious breathing problems and other side effects. Always follow the prescribed dose. - Myth: It is safe to give this medicine to children for cough.
Fact: This medicine is not recommended for children below 12 years because of the risk of serious breathing problems. - Myth: It is fine to drink alcohol with cough syrup.
Fact: Alcohol increases drowsiness and the risk of slow or shallow breathing and must be avoided.
🔄 Alternative Options
Generic Alternatives
- Chlorpheniramine maleate + codeine oral syrup
Brand Alternatives
- Ascoril C Syrup