dk fam 50 mg/20 mg tablet - Diclofenac (50mg) + Famotidine (20mg) medicine

DK Fam 50 mg/20 mg Tablet: Complete Medicine Guide

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🏭 Somatico Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Diclofenac is generally avoided during the third trimester due to risk of premature closure of the ductus arteriosus. Famotidine is considered safe in pregnancy. Consult your doctor for individualized advice. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is dk fam 50 mg/20 mg tablet used for?

This medicine is a combination of diclofenac, an anti-inflammatory pain reliever, and famotidine, a stomach acid reducer. It is used for short-term relief of acute pain while protecting the stomach from diclofenac-induced irritation.

  • Generic Name: Diclofenac (50mg) + Famotidine (20mg)
  • Manufacturer: Somatico Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dk fam 50 mg/20 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डाइक्लोफेनाक और फैमोटिडीन का संयोजन है। यह दर्द, सूजन और जलन को कम करने के लिए दी जाती है, साथ ही पेट की एसिडिटी को कम करके पेट की सुरक्षा करती है। इसका उपयोग मुख्य रूप से जोड़ों के दर्द, मांसपेशियों के दर्द, कमर दर्द, मासिक धर्म के दर्द और सर्जरी के बाद के दर्द में किया जाता है। यह दवा पेट में अल्सर, गुर्दे या लीवर की गंभीर बीमारी, दिल की विफलता, या एस्पिरिन से एलर्जी वाले लोगों के लिए नहीं है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में पेट दर्द, जलन, मतली, उल्टी, दस्त, कब्ज, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में अल्सर या रक्तस्राव, गुर्दे की समस्या, लीवर की क्षति, गंभीर एलर्जी प्रतिक्रिया और दिल का दौरा या स्ट्रोक का खतरा शामिल हो सकता है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, सीने में दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा या आंखों का पीलापन दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक या अवधि से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट की जलन कम हो। इस दवा के साथ शराब न लें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें। यदि आपको पेट में अल्सर, गुर्दे या लीवर की बीमारी, दिल की बीमारी, या अस्थमा है तो डॉक्टर को बताएं। गर्भावस्था के अंतिम तीन महीनों में इस दवा का उपयोग न करें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 dk fam 50 mg/20 mg tablet Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as back pain, sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgical procedures.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Helps relieve menstrual cramps and associated pain.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Provides symptomatic relief of pain and stiffness in osteoarthritis, especially when gastric protection is needed.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Used as an adjunct for pain relief in rheumatoid arthritis, though disease-modifying therapy is primary.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Acute gout","description":"Sometimes used off-label for short-term relief of acute gout attacks.","evidence":"Limited"},{"condition":"Migraine","description":"Occasionally used off-label for acute migraine treatment, but not first-line.","evidence":"Limited"}]

Primary treatment for: Acute musculoskeletal pain

Also treats: Osteoarthritis, Rheumatoid arthritis, Dysmenorrhea, Post-operative pain

📋 Drug Information

Generic Name(s)Diclofenac (50mg) + Famotidine (20mg)
Brand Namedk fam 50 mg/20 mg tablet
ManufacturerSomatico Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to minimize stomach upset.
2
Do not exceed the recommended dose or duration without medical advice.
3
Avoid alcohol completely while taking this medicine.
4
Inform your doctor if you have a history of stomach ulcers, kidney, liver, or heart disease.
5
Do not take other NSAIDs or pain relievers concurrently without consulting your doctor.
6
Report any signs of gastrointestinal bleeding, such as black stools or vomiting blood, immediately.
7
Use the lowest effective dose for the shortest possible duration.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Menstrual cramps
This medicine can help relieve dysmenorrhea.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDiclofenac is rapidly and completely absorbed from the gastrointestinal tract after oral administration. Famotidine is also rapidly absorbed, with bioavailability of about 40-45%.
DistributionDiclofenac is highly bound to plasma proteins and distributes into synovial fluid. Famotidine distributes widely but does not cross the blood-brain barrier significantly.
Protein BindingDiclofenac: greater than 99% bound to plasma proteins, primarily albumin. Famotidine: approximately 15-20% bound to plasma proteins.
MetabolismDiclofenac is extensively metabolized in the liver by cytochrome P450 enzymes, mainly CYP2C9, to several metabolites. Famotidine is minimally metabolized in the liver, with most of the drug excreted unchanged.
Half-LifeDiclofenac: approximately 1-2 hours. Famotidine: approximately 2.5-3.5 hours.
ExcretionDiclofenac metabolites are excreted mainly in urine and bile. Famotidine is primarily excreted unchanged in urine.
BioavailabilityDiclofenac: approximately 50-60% due to first-pass metabolism. Famotidine: approximately 40-45%.
Onset of ActionDiclofenac: analgesic effects begin within 30-60 minutes. Famotidine: acid suppression begins within 1 hour.
Peak Plasma TimeDiclofenac: 1-2 hours. Famotidine: 1-3 hours.
Duration of ActionDiclofenac: 4-6 hours. Famotidine: up to 10-12 hours.

How It Works

Diclofenac inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the production of prostaglandins, which are mediators of pain, inflammation, and fever. Famotidine competitively blocks histamine H2 receptors on gastric parietal cells, reducing gastric acid secretion. This combination provides analgesic and anti-inflammatory effects while mitigating the risk of diclofenac-induced gastric irritation.

Mechanism Steps

1
COX enzyme inhibition by diclofenac: Diclofenac binds to and reversibly inhibits cyclooxygenase enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: Decreased prostaglandin levels lead to reduced pain, inflammation, and fever.
3
H2 receptor blockade by famotidine: Famotidine competitively blocks histamine H2 receptors on gastric parietal cells, reducing cyclic AMP and gastric acid secretion.
4
Gastric protection: Reduced acid secretion helps prevent diclofenac-induced gastric mucosal damage and ulcer formation.

💡 How to Take dk fam 50 mg/20 mg tablet

Strength: Tablet containing diclofenac 50 mg and famotidine 20 mg.

1Take the tablet orally with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the prescribed schedule exactly.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally one to two times daily, depending on the severity of pain and the prescribing doctor's judgment. The maximum recommended daily dose is 100 mg of diclofenac. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose reduction may be necessary. Consult your doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose reduction may be necessary. Consult your doctor for individualized dosing.
Maximum Daily DoseDiclofenac: 100 mg per day. Famotidine: 40 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.
Caffeine
Limit
May increase stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of dk fam 50 mg/20 mg tablet

✅ Common Side Effects

Stomach pain (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Heartburn (Common (5-10%))
Avoid spicy foods. If symptoms continue, consult your doctor.
Nausea (Common (5-10%))
Take with a meal. If vomiting occurs, contact your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. If severe, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stools, vomiting blood, or severe abdominal pain.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Liver damage (Rare (<0.1%))
Seek medical help if you experience yellowing of skin or eyes, dark urine, or severe fatigue.
Severe allergic reaction (Rare (<0.1%))
Call emergency services if you have swelling of face, lips, or throat, or difficulty breathing.
Cardiovascular events (Rare (<0.1%))
Seek immediate care for chest pain, shortness of breath, or sudden weakness.

⚠️ Rare Side Effects

Aseptic meningitis
Seek immediate medical attention if you experience severe headache, stiff neck, or sensitivity to light.
Pancreatitis
Go to the emergency room if you have severe upper abdominal pain radiating to your back.
Stevens-Johnson syndrome
Seek immediate medical care if you develop a rash with blisters, peeling skin, or sores in your mouth.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
ACE inhibitors Major
Lithium Major
Methotrexate Major
Corticosteroids Moderate
Diuretics Moderate
Antacids Moderate
Aspirin Minor
Ketoconazole Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs
  • ACE inhibitors
  • Lithium
  • Methotrexate

⚡ Moderate Interactions

  • Corticosteroids
  • Diuretics
  • Antacids

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and can worsen stomach irritation caused by diclofenac.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active peptic ulcer or history of recurrent ulcers","Severe heart failure","Severe kidney impairment","Severe liver impairment","History of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs","Third trimester of pregnancy","Coronary artery bypass graft surgery"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach upset.","Avoid alcohol.","Do not use for longer than prescribed without medical supervision.","Use with caution in elderly patients.","Inform your doctor if you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma.","Do not take other NSAIDs concurrently.","May cause dizziness; avoid driving until you know how it affects you."]

🤱 Lactation Safety

Diclofenac and famotidine are excreted in breast milk in small amounts. Consult your doctor before use during breastfeeding.

💊 Overdose Management

Overdose may cause nausea, vomiting, abdominal pain, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, or liver damage. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or a glass of milk to reduce stomach upset. Avoid alcohol while taking this medicine, as it can increase the risk of stomach bleeding. Do not take other NSAIDs or pain relievers without consulting your doctor. If you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma, inform your doctor before taking this medicine. Do not use this medicine during the last trimester of pregnancy unless specifically advised by your doctor. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Regular monitoring of kidney and liver function is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. Diclofenac is generally avoided during the third trimester due to risk of premature closure of the ductus arteriosus. Famotidine is considered safe in pregnancy.

🏥 Post-Surgery Considerations

This medicine may be prescribed for post-operative pain. Follow your surgeon's instructions regarding dosing and duration. Inform your surgeon if you have a history of stomach ulcers or kidney disease.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may increase the risk of bleeding during dental work. Your dentist may advise you to stop it temporarily.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Stay well hydrated.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may cause injury while taking this medicine, as it may mask pain and lead to overexertion. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce processed food intake.
Stay well hydrated.
Avoid spicy and acidic foods to reduce stomach irritation.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take it with food and to inform your employer if your job involves operating machinery.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach bleeding, kidney problems, or allergic reactions. Do not stop abruptly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver damage, and cardiovascular events. Regular monitoring of kidney and liver function, blood counts, and blood pressure is recommended. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Topical NSAIDs

May provide localized pain relief with fewer systemic side effects.

Evidence: Well-established
Acupuncture

May help with certain types of pain.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture and heat. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within two weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with acute back pain and a history of gastritis
Was prescribed this combination for short-term back pain relief. He was advised to take it with meals and to avoid alcohol. He experienced good pain relief without any stomach discomfort.
💡 Lesson: The addition of famotidine helps protect the stomach in patients at risk of NSAID-induced gastritis.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Diclofenac starts relieving pain within 30-60 minutes, while famotidine begins reducing stomach acid within 1 hour.

Q: Can I take this medicine on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset.

Q: Is it safe to take this medicine with other pain relievers?

A: No, combining with other NSAIDs can increase the risk of side effects. Consult your doctor before taking any other pain reliever.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for dk fam 50 mg/20 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken on an empty stomach.
    Fact: It should be taken with food to reduce stomach upset.
  • Myth: This medicine is safe for long-term use without monitoring.
    Fact: Long-term use requires regular monitoring of kidney and liver function.
  • Myth: This medicine can be taken with other pain relievers.
    Fact: Combining with other NSAIDs increases the risk of side effects.

🔄 Alternative Options

Generic Alternatives

  • Diclofenac 50 mg + Famotidine 20 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Diclofenac 50 mg + Famotidine 20 mg","onset":"30-60 minutes","duration":"4-6 hours","gastric_protection":"Yes"},{"medicine":"Diclofenac alone","composition":"Diclofenac 50 mg","onset":"30-60 minutes","duration":"4-6 hours","gastric_protection":"No"},{"medicine":"Diclofenac + Omeprazole","composition":"Diclofenac 50 mg + Omeprazole 20 mg","onset":"30-60 minutes","duration":"4-6 hours","gastric_protection":"Yes"}]

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