colispas oral drops
What is colispas oral drops used for?
Alspas (Dicyclomine + Dimethicone) is used to treat GASTRO INTESTINAL. It contains Dicyclomine (10mg) + Dimethicone (40mg), which Dicyclomine: Antimuscarinic, relaxes smooth muscle; Dimethicone: Defoaming agent. Always consult your doctor before use. Take as prescribed.
- Generic Name: Dicyclomine + Dimethicone
- Manufacturer: Osho Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ colispas oral drops Uses & Benefits
Irritable bowel syndrome, abdominal cramps, flatulence, dyspepsia
Off-label uses: Infant colic (not recommended), functional dyspepsia
๐ Drug Information
| Generic Name(s) | Dicyclomine + Dimethicone |
| Brand Name | Alspas |
| Manufacturer | Osho Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic + Antiflatulent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Dicyclomine: Antimuscarinic, relaxes smooth muscle; Dimethicone: Defoaming agent, reduces gas surface tension
Mechanism Steps
๐ก How to Take colispas oral drops
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of colispas oral drops
โ Common Side Effects
- Dry mouth
- Dizziness
- Blurred vision
- Constipation
- Nausea
- Drowsiness
๐จ Serious Side Effects
- Paralytic ileus
- Urinary retention
- Tachycardia
- Hallucinations
- Heat stroke
โ ๏ธ Rare Side Effects
- Anaphylaxis
- Agranulocytosis
- Hepatitis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Anticholinergics | Major | Additive anticholinergic effects |
| Amantadine | Major | Increased anticholinergic side effects |
| Haloperidol | Major | Decreased antipsychotic efficacy |
| Phenothiazines | Major | Increased anticholinergic effects |
| Tricyclic antidepressants | Major | Additive anticholinergic effects |
| Antacids | Moderate | Reduced absorption of dicyclomine |
| Antidiarrheals | Moderate | Increased anticholinergic effects |
| Ketoconazole | Moderate | Increased dicyclomine levels |
| Metoclopramide | Moderate | Antagonism of GI effects |
| Cimetidine | Minor | Possible increased dicyclomine levels |
| Ranitidine | Minor | Possible increased dicyclomine levels |
๐จ Major Interactions
- Anticholinergics
- Amantadine
- Haloperidol
- Phenothiazines
- Tricyclic antidepressants
โก Moderate Interactions
- Antacids
- Antidiarrheals
- Ketoconazole
- Metoclopramide
โน๏ธ Minor Interactions
- Cimetidine
- Ranitidine
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
Increased CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, glaucoma, obstructive uropathy, myasthenia gravis, gastrointestinal obstruction, severe ulcerative colitis, reflux esophagitis
๐ Monitoring Parameters
Monitor for anticholinergic side effects, bowel sounds, abdominal distension
๐คฑ Lactation Safety
Caution; dicyclomine may suppress lactation
๐ Overdose Management
Gastric lavage, activated charcoal, supportive measures; physostigmine for severe anticholinergic symptoms
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose