cofset syrup
What is cofset syrup used for?
Axn Syrup (Phenylpropanolamine + Chlorpheniramine Maleate) is used to treat RESPIRATORY. It contains Phenylpropanolamine (12.5mg) + Chlorpheniramine Maleate (2mg), which Phenylpropanolamine: alpha-adrenergic agonist causing vasoconstriction and decon. Always consult your doctor before use. Take as prescribed.
- Generic Name: Phenylpropanolamine + Chlorpheniramine Maleate
- Manufacturer: Orison Pharma International
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cofset syrup Uses & Benefits
Symptomatic relief of nasal congestion, rhinorrhea, sneezing due to common cold, allergic rhinitis, sinusitis
Off-label uses: Weight loss (Phenylpropanolamine historically used)
๐ Drug Information
| Generic Name(s) | Phenylpropanolamine + Chlorpheniramine Maleate |
| Brand Name | Axn Syrup |
| Manufacturer | Orison Pharma International |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Sympathomimetic + Antihistamine |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Phenylpropanolamine: alpha-adrenergic agonist causing vasoconstriction and decongestion; Chlorpheniramine: H1-receptor antagonist blocking histamine effects
Mechanism Steps
๐ก How to Take cofset syrup
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cofset syrup
โ Common Side Effects
- Drowsiness
- Dry mouth
- Nervousness
- Insomnia
- Dizziness
๐จ Serious Side Effects
- Hypertension
- Arrhythmias
- Seizures
- Urinary retention
- Allergic reactions
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Thrombocytopenia
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis |
| Beta-blockers | Major | Reduced antihypertensive effect |
| Antihypertensives | Major | Reduced blood pressure control |
| CNS depressants | Moderate | Enhanced sedation |
| Anticholinergics | Moderate | Increased anticholinergic effects |
| Tricyclic antidepressants | Moderate | Increased sympathomimetic effects |
| Antacids | Minor | Possible altered absorption |
| Caffeine | Minor | Additive stimulant effect |
๐จ Major Interactions
- MAOIs
- Beta-blockers
- Antihypertensives
โก Moderate Interactions
- CNS depressants
- Anticholinergics
- Tricyclic antidepressants
โน๏ธ Minor Interactions
- Antacids
- Caffeine
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase absorption
๐ท Alcohol Interaction
Increased CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypertension, cardiovascular disease, hyperthyroidism, glaucoma, MAOI use, urinary retention
๐ Monitoring Parameters
Blood pressure, heart rate, CNS status, symptom relief
๐คฑ Lactation Safety
Caution; excreted in breast milk
๐ Overdose Management
Supportive care; activated charcoal if recent ingestion; monitor vital signs; treat hypertension with phentolamine; treat CNS depression with supportive measures
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.