Acelamine Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe headache with blurred vision
- Chest pain or palpitations
- Difficulty breathing or swelling of face/lips/throat
- Yellowing of skin or eyes
- Dark urine or severe abdominal pain
- Unusual bleeding or bruising
- Seizures or confusion
If experiencing severe symptoms, call emergency services immediately.
What is acelamine tablet used for?
This medicine is a combination of Paracetamol and Phenylpropanolamine used for short-term relief of nasal congestion, headache, and fever associated with colds and allergies. It works by reducing fever and pain and constricting nasal blood vessels.
- Generic Name: Paracetamol + Phenylpropanolamine
- Manufacturer: Orison Pharma International
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acelamine tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल और फेनिलप्रोपेनॉलामाइन का संयोजन है, जिसका उपयोग सर्दी, एलर्जी और साइनसाइटिस से जुड़ी नाक की भीड़, सिरदर्द, बदन दर्द और बुखार के लक्षणों से राहत के लिए किया जाता है। यह नाक के रक्त वाहिकाओं को सिकोड़कर भीड़ कम करती है और दर्द व बुखार को कम करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, मुँह सूखना, सिरदर्द, चक्कर आना और घबराहट शामिल हैं। फेनिलप्रोपेनॉलामाइन के कारण हृदय गति बढ़ सकती है और रक्तचाप बढ़ सकता है। गंभीर दुष्प्रभावों में तेज रक्तचाप, अनियमित हृदय गति, और यकृत क्षति शामिल हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे यकृत को नुकसान हो सकता है। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड या ग्लूकोमा है, तो डॉक्टर को बताएं। 5-7 दिनों से अधिक इसका उपयोग न करें। चक्कर आने पर वाहन न चलाएं। बच्चों की पहुंच से दूर रखें।
💊 acelamine tablet Uses & Benefits
[{"condition":"Common cold with nasal congestion","description":"Relieves nasal stuffiness, headache, body ache, and fever associated with the common cold.","evidence":"Well-established for short-term symptomatic relief."},{"condition":"Allergic rhinitis","description":"Helps reduce nasal congestion and associated headache in allergic rhinitis.","evidence":"Limited evidence; used for symptomatic relief."},{"condition":"Sinusitis","description":"Provides symptomatic relief of nasal congestion and pain in sinusitis.","evidence":"Limited evidence; used as adjunctive therapy."}]
Off-label uses: [{"condition":"Tension headache with nasal congestion","description":"Sometimes used off-label for headache when accompanied by nasal congestion.","evidence":"Limited"}]
Primary treatment for: Common cold
Also treats: Allergic rhinitis, Sinusitis
📋 Drug Information
| Generic Name(s) | Paracetamol + Phenylpropanolamine |
| Brand Name | Anglocet Plus Tablet |
| Manufacturer | Orison Pharma International |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Analgesic, Antipyretic, Decongestant |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Paracetamol acts primarily in the central nervous system to reduce pain and fever, likely by inhibiting prostaglandin synthesis in the brain. Phenylpropanolamine is a sympathomimetic amine that directly and indirectly stimulates alpha-adrenergic receptors, causing vasoconstriction in the nasal mucosa, which reduces swelling and congestion. It also has some beta-adrenergic activity that can increase heart rate and blood pressure.
Mechanism Steps
💡 How to Take acelamine tablet
Strength: Tablet: Paracetamol 500 mg + Phenylpropanolamine 12.5 mg
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally every 4 to 6 hours as needed for symptoms, not to exceed 4 tablets in 24 hours. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the maximum daily dose of Paracetamol 2000 mg (4 tablets) from all sources. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the cardiovascular effects of Phenylpropanolamine. Use with caution and lower doses may be appropriate. Consult a doctor for individualized dosing. |
| Renal Impairment | Dose adjustment may be needed in patients with renal impairment. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Dose adjustment may be needed in patients with hepatic impairment. Paracetamol should be used with caution and at reduced doses. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | Maximum daily dose: 4 tablets in 24 hours. Do not exceed 2000 mg of Paracetamol per day from all sources. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acelamine tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Warfarin | Major | |
| Beta-blockers | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Caffeine | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Other sympathomimetic amines
- Warfarin
⚡ Moderate Interactions
- Beta-blockers
- Tricyclic antidepressants
- Caffeine
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of Paracetamol-induced liver damage and may worsen Phenylpropanolamine-related cardiovascular effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Uncontrolled hypertension","Severe coronary artery disease","Hyperthyroidism","Concurrent use of MAOIs or within 14 days of stopping MAOIs","Severe liver disease","Severe kidney disease","Known hypersensitivity to Paracetamol or Phenylpropanolamine"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose of Paracetamol; higher doses can cause liver damage.","Use with caution in patients with cardiovascular disease, diabetes, glaucoma, or prostatic hypertrophy.","Avoid alcohol while taking this medicine.","Do not use for more than 5-7 days without consulting a doctor.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Paracetamol is considered safe during breastfeeding in usual doses. Phenylpropanolamine may pass into breast milk and could cause adverse effects in the infant. Consult your doctor before use.
💊 Overdose Management
Overdose of Paracetamol can cause severe liver damage. Symptoms may include nausea, vomiting, abdominal pain, and yellowing of skin or eyes. Seek immediate medical attention. The antidote is N-acetylcysteine, which is most effective when given within 8-10 hours of overdose. Phenylpropanolamine overdose can cause severe hypertension, tachycardia, and arrhythmias; supportive care and blood pressure monitoring are required.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose. Avoid alcohol while taking this medicine because it increases the risk of liver damage from Paracetamol. Do not use this medicine for more than 5-7 days without consulting a doctor. If you have high blood pressure, heart disease, diabetes, thyroid problems, or glaucoma, inform your doctor before taking this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat. Do not use this medicine if you are pregnant or breastfeeding without medical advice. Always check with your doctor before taking any other cold or pain medicine to avoid duplication of Paracetamol.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the cardiovascular effects of Phenylpropanolamine. Use with caution and monitor blood pressure regularly. Lower doses may be appropriate.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Paracetamol is generally considered safe, but Phenylpropanolamine may not be safe.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect blood pressure.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with anesthetics or other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while taking this medicine, especially if you experience dizziness or palpitations. Light activity is fine if you feel up to it.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to rest at home if you have a fever or severe symptoms.
🛑 When to Stop This Medicine
Stop taking this medicine if your symptoms improve or after 5-7 days of use. If symptoms persist or worsen, consult your doctor. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of Paracetamol can increase the risk of liver damage, especially with alcohol. Phenylpropanolamine can cause cardiovascular effects such as increased blood pressure and heart rate. Regular monitoring may be required if used for extended periods under medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps relieve nasal congestion without medication.
Evidence: Well-establishedCan temporarily relieve nasal stuffiness.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccinations while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check local customs regulations regarding carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30-60 minutes for pain and fever, and within 15-30 minutes for nasal decongestion.
A: Do not take with other medicines containing Paracetamol or decongestants without consulting your doctor, as it may lead to overdose.
A: It should be used with caution in people with high blood pressure because Phenylpropanolamine can raise blood pressure. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for acelamine tablet
View AllAlternative brands with exact same active ingredient:
-
m cold plus tabletAbbott ₹5.79 55.9% CHEAPER
-
veerest tabletVivid Labs Pvt Ltd ₹10.31 21.5% CHEAPER
-
arrest 500mg/12.5mg/10mg tabletWelbe Life Sciences ₹17.50 33.3% COSTLIER
-
nosopen tabletBhavishya Pharmaceuticals Pvt Ltd ₹20.00 52.3% COSTLIER
-
s cold tabletSarb Pharmaceuticals ₹20.00 52.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for everyone.
Fact: It is not safe for people with uncontrolled hypertension, heart disease, or those taking MAOIs. - Myth: More is better for faster relief.
Fact: Taking more than the recommended dose can cause serious liver damage and cardiovascular effects.
🔄 Alternative Options
Generic Alternatives
- Paracetamol + Phenylpropanolamine combination generics