clonin tablet - Clomiphene (50mg) + Coenzyme Q10 (50mg) medicine

CCQ 50 Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Bryson Pharmaceutical Llp 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
🤰 Pregnancy Category Not established from the available information. Clomiphene is not recommended during pregnancy. Coenzyme Q10 is generally considered safe but consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for ovulation induction; limited for combination with coenzyme Q10.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe abdominal pain or bloating
  • Rapid weight gain over a few days
  • Difficulty breathing or shortness of breath
  • Blurred vision or double vision
  • Severe nausea or vomiting
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is clonin tablet used for?

This medicine is a combination of clomiphene and coenzyme Q10 used to treat infertility by stimulating ovulation in women. It works by increasing hormone levels that trigger egg release, while coenzyme Q10 provides antioxidant support.

  • Generic Name: Clomiphene + Coenzyme Q10
  • Manufacturer: Bryson Pharmaceutical Llp
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 clonin tablet के बारे में (Hindi Summary)

उपयोग: यह दवा क्लोमिफीन और कोएंजाइम क्यू10 का संयोजन है, जिसका उपयोग महिलाओं में ओव्यूलेशन को प्रेरित करने और बांझपन के इलाज के लिए किया जाता है। यह मस्तिष्क में एस्ट्रोजन रिसेप्टर्स को अवरुद्ध करके फॉलिकल-स्टिमुलेटिंग हार्मोन और ल्यूटिनाइजिंग हार्मोन के स्तर को बढ़ाती है, जिससे अंडाशय में अंडे का विकास और रिलीज होता है। कोएंजाइम क्यू10 एक एंटीऑक्सिडेंट है जो प्रजनन कोशिकाओं को ऑक्सीडेटिव तनाव से बचाने में मदद करता है। यह दवा केवल डॉक्टर की सलाह पर लेनी चाहिए और इसका सेवन उन महिलाओं के लिए नहीं है जो पहले से गर्भवती हैं या जिन्हें लीवर की बीमारी है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में गर्म लहरें, पेट में सूजन या असुविधा, स्तन में कोमलता, मतली, सिरदर्द और मूड में बदलाव शामिल हैं। कुछ महिलाओं को धुंधली दृष्टि या दृष्टि में अन्य बदलाव हो सकते हैं, जिसकी तुरंत डॉक्टर को सूचना देनी चाहिए। दुर्लभ लेकिन गंभीर दुष्प्रभावों में ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम शामिल है, जिसमें तेजी से वजन बढ़ना, गंभीर पेट दर्द, उल्टी और सांस लेने में कठिनाई हो सकती है। इस स्थिति में तुरंत आपातकालीन चिकित्सा सहायता लें।

सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अपनी मर्जी से खुराक न बढ़ाएं या घटाएं। इलाज शुरू करने से पहले अपने सभी चिकित्सीय इतिहास, विशेषकर लीवर की समस्या, थायरॉइड विकार या ओवेरियन सिस्ट के बारे में डॉक्टर को बताएं। नियमित जांच कराएं, जिसमें पेल्विक परीक्षण और अल्ट्रासाउंड शामिल हो सकता है। यदि आपको दृष्टि में बदलाव महसूस हो, तो दवा बंद करें और तुरंत डॉक्टर से संपर्क करें। गर्भवती होने पर यह दवा न लें। शराब का सेवन न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 clonin tablet Uses & Benefits

[{"condition":"Ovulation induction in anovulatory infertility","description":"This medicine is used to stimulate the release of eggs in women who do not ovulate regularly, often due to polycystic ovary syndrome or other hormonal imbalances.","evidence":"Well-established"},{"condition":"Unexplained infertility","description":"It may be prescribed to increase the number of eggs released per cycle, improving the chance of conception when no clear cause of infertility is found.","evidence":"Moderate"},{"condition":"Male infertility with low sperm count or motility","description":"Sometimes used off-label in men to improve sperm production, though evidence is limited and it is not a standard first-line treatment.","evidence":"Limited"}]

Off-label uses: [{"condition":"Male hypogonadism","description":"Rarely used to raise testosterone levels in men with low testosterone, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Gynecomastia in men","description":"Occasionally prescribed to reduce breast enlargement in men, but evidence is not strong.","evidence":"Limited"}]

Primary treatment for: Anovulatory infertility

Also treats: Polycystic ovary syndrome, Unexplained infertility

📋 Drug Information

Generic Name(s)Clomiphene + Coenzyme Q10
Brand NameCCQ 100 Tablet
ManufacturerBryson Pharmaceutical Llp
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassOvulation stimulant / Antioxidant
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed, usually for 5 days starting early in your menstrual cycle.
2
Take the tablet with food to improve absorption and reduce stomach upset.
3
Monitor your ovulation with basal body temperature or ovulation predictor kits.
4
Report any visual changes immediately and stop the medicine.
5
Avoid alcohol while taking this medicine to reduce liver stress.
6
Keep all follow-up appointments for ultrasound and blood tests.
7
Do not take this medicine if you are pregnant or suspect you might be pregnant.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Irregular periods or no ovulation
This medicine is commonly prescribed for this.
Likely Use
✅
Infertility
This medicine is used to induce ovulation.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClomiphene is well absorbed from the gastrointestinal tract after oral administration. Coenzyme Q10 is also absorbed orally, but its absorption can be variable and is enhanced when taken with food containing fat.
DistributionClomiphene is widely distributed in body tissues, including the reproductive organs. Coenzyme Q10 is distributed to various tissues, with higher concentrations in organs that have high energy demands, such as the heart, liver, and kidneys.
Protein BindingClomiphene is highly bound to plasma proteins. Coenzyme Q10 is also highly protein-bound in plasma.
MetabolismClomiphene is metabolized in the liver, primarily by cytochrome P450 enzymes. Coenzyme Q10 undergoes metabolism in the liver and other tissues, but detailed pathways are not fully established.
Half-LifeThe elimination half-life of clomiphene is approximately 5 to 7 days. The half-life of coenzyme Q10 is not well established from available information.
ExcretionClomiphene and its metabolites are excreted mainly in the feces via bile, with a smaller amount excreted in urine. Coenzyme Q10 is excreted primarily in bile and feces.
BioavailabilityThe oral bioavailability of clomiphene is approximately 25% to 50% in some studies, but it can vary. The bioavailability of coenzyme Q10 is variable and depends on the formulation and presence of dietary fat.
Onset of ActionOvulation typically occurs about 5 to 10 days after the last dose of clomiphene in a treatment cycle. The antioxidant effects of coenzyme Q10 are not immediate and may take weeks to manifest.
Peak Plasma TimePeak plasma levels of clomiphene are reached within 6 hours after oral administration. Peak levels of coenzyme Q10 are reached within 5 to 10 hours, depending on the formulation.
Duration of ActionThe ovulatory effect of clomiphene lasts for the duration of the treatment cycle, usually about 5 days of dosing followed by ovulation within 5 to 10 days. Coenzyme Q10 has a longer duration of action due to its accumulation in tissues.

How It Works

Clomiphene works by binding to estrogen receptors in the hypothalamus and pituitary gland, blocking the normal feedback inhibition by estrogen. This leads to increased secretion of gonadotropin-releasing hormone, which in turn raises follicle-stimulating hormone and luteinizing hormone levels. Higher levels of these hormones stimulate the ovaries to develop follicles and trigger ovulation. Coenzyme Q10 is a fat-soluble antioxidant that participates in mitochondrial energy production and helps reduce oxidative stress, which may support egg and sperm quality. The combination is intended to improve ovulatory function while providing antioxidant support for reproductive cells.

Mechanism Steps

1
Estrogen receptor blockade: Clomiphene binds to estrogen receptors in the hypothalamus and pituitary, preventing estrogen from exerting its normal negative feedback.
2
Increased GnRH secretion: With estrogen feedback blocked, the hypothalamus increases its release of gonadotropin-releasing hormone.
3
Rise in FSH and LH: Higher GnRH levels stimulate the pituitary to secrete more follicle-stimulating hormone and luteinizing hormone into the bloodstream.
4
Ovarian stimulation: Elevated FSH and LH levels promote the growth of ovarian follicles and eventually trigger ovulation.
5
Antioxidant support: Coenzyme Q10 helps reduce oxidative stress in reproductive tissues, potentially improving egg and sperm quality.

💡 How to Take clonin tablet

Strength: Each tablet contains clomiphene 50 mg and coenzyme Q10 50 mg.

1Take the tablet by mouth with a glass of water.
2Take it with food to improve absorption of coenzyme Q10 and reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at the same time each day to maintain consistent levels.
5Follow the specific schedule given by your doctor, usually for 5 days starting early in your cycle.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once daily for 5 days, starting on the 5th day of the menstrual cycle, or as directed by your fertility specialist. The dose may be adjusted based on your response and ovulation. Some women may need a higher dose or a different schedule. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageThis medicine is not intended for use in elderly patients for fertility treatment. Safety and efficacy have not been established in this population.
Renal ImpairmentNo specific dose adjustment is provided for renal impairment. Use with caution and consult your doctor.
Hepatic ImpairmentThis medicine is contraindicated in patients with liver disease. Consult your doctor for alternative treatment.
Maximum Daily DoseThe maximum recommended dose is 150 mg per day for clomiphene, but the dose in this product is fixed at 50 mg. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Enhances absorption of coenzyme Q10 and reduces stomach upset.
Grapefruit
Avoid
May increase clomiphene levels by affecting liver enzymes.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of clonin tablet

✅ Common Side Effects

Hot flushes (Common (10-20%))
Usually harmless. Wear light clothing and stay cool. Consult doctor if severe.
Abdominal bloating or discomfort (Common (5-10%))
Eat small frequent meals. Report if pain becomes severe.
Breast tenderness (Common (5-10%))
Wear a supportive bra. Consult doctor if persistent.
Nausea (Common (5-10%))
Take with food. If vomiting occurs, contact doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Use paracetamol if needed, but consult doctor first.
Mood swings (Common (5-10%))
Practice stress-reduction techniques. Talk to your doctor if severe.

🚨 Serious Side Effects

Ovarian hyperstimulation syndrome (OHSS) (Rare (<1%))
Seek immediate medical attention if you have rapid weight gain, severe abdominal pain, vomiting, or difficulty breathing.
Visual disturbances (Rare (<1%))
Stop the medicine and contact your doctor immediately if you notice blurred vision, double vision, or seeing spots.
Ovarian cysts (Uncommon (1-5%))
Report pelvic pain or swelling to your doctor. May require ultrasound monitoring.
Multiple pregnancy (Uncommon (5-10%))
Discuss the risks with your doctor. Requires close monitoring during pregnancy.

⚠️ Rare Side Effects

Severe allergic reaction
Seek emergency care if you experience rash, swelling of face or throat, or difficulty breathing.
Liver toxicity
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Gonadotropins Major
Hormonal contraceptives Major
Warfarin Moderate
Thyroid hormones Moderate
Grapefruit juice Moderate

🚨 Major Interactions

  • Other fertility drugs (e.g., gonadotropins)
  • Hormonal contraceptives

⚡ Moderate Interactions

  • Thyroid hormones
  • Anticoagulants (e.g., warfarin)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase the risk of liver problems and worsen mood swings. It may also affect fertility treatment outcomes.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to clomiphene or coenzyme Q10","Pregnancy","Liver disease","Unexplained abnormal vaginal bleeding","Ovarian cysts not due to polycystic ovary syndrome","Primary ovarian failure"]

⚠️ Warnings & Precautions

["This medicine should only be used under the supervision of a fertility specialist.","Visual disturbances may occur; stop the medicine and consult your doctor if they happen.","Multiple pregnancies (twins, triplets) are possible; discuss risks with your doctor.","Ovarian hyperstimulation syndrome can be serious; report symptoms immediately.","Avoid alcohol while taking this medicine.","Inform your doctor if you have thyroid or adrenal gland problems.","Do not take this medicine if you are already pregnant."]

🤱 Lactation Safety

It is not known whether clomiphene passes into breast milk. Coenzyme Q10 may pass into breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose of this medicine may cause severe ovarian hyperstimulation, visual disturbances, and abdominal pain. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your fertility specialist. Do not increase or decrease the dose on your own. Before starting treatment, tell your doctor about all your medical conditions, especially liver problems, thyroid disorders, or a history of ovarian cysts. Also share a complete list of all medicines, vitamins, and herbal supplements you take, because some drugs can interact with clomiphene. You should have regular check-ups, including pelvic examination and possibly ultrasound, to monitor your response. If you experience visual changes, stop the medicine and contact your doctor immediately. Avoid alcohol while taking this medicine, as it can worsen mood changes and liver stress. Do not take this medicine if you are already pregnant. If you think you might be pregnant, stop the medicine and inform your doctor right away. Keep this medicine out of the reach of children and store it as directed on the label.

👴 Special Considerations for Elderly

💡 For Patients Above 65

This medicine is not intended for use in elderly patients for fertility treatment. Safety and efficacy have not been established.

🤰 Pregnancy Planning (TTC)

This medicine is used to help achieve pregnancy. If you become pregnant, stop the medicine immediately and inform your doctor. It is not safe to take during pregnancy.

🏥 Post-Surgery Considerations

If you are planning surgery, inform your surgeon that you are taking this medicine. It may need to be stopped before surgery due to potential effects on blood clotting.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. No specific precautions are usually needed, but it is important for your dentist to know your medication history.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to improve fertility outcomes.
🥗
Eat a balanced diet rich in antioxidants.
😴
Exercise regularly but avoid excessive strenuous activity.
💧
Reduce stress through yoga or meditation.
🧘
Get adequate sleep to support hormonal balance.
🌞
Avoid smoking and alcohol.

🏋️ Exercise Considerations

Moderate exercise is generally safe while taking this medicine. However, if you experience abdominal pain or bloating, avoid strenuous activities and consult your doctor.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Eat plenty of fruits and vegetables.
Choose whole grains over refined carbohydrates.
Stay well hydrated.
Limit caffeine and processed foods.

💼 Impact on Daily Work & Life

This medicine may cause visual disturbances or mood swings in some people. If affected, avoid driving or operating heavy machinery. Otherwise, it usually does not interfere with daily activities.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor immediately if you experience visual changes, severe abdominal pain, or suspect pregnancy. Do not stop without consulting your doctor if you are in the middle of a treatment cycle.

📅 Long-Term Use Effects

Long-term use of this medicine beyond the recommended duration is not advised without medical supervision. Prolonged use may increase the risk of ovarian cysts and visual disturbances. Regular monitoring of liver function and ovarian response is recommended. Coenzyme Q10 is generally safe for long-term use, but consult your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Letrozole

Another oral ovulation inducer, often used in PCOS.

Evidence: Well-established
Gonadotropins

Injectable hormones for ovulation induction.

Evidence: Well-established
Lifestyle modifications

Weight loss, diet, and exercise can improve ovulation in PCOS.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light and moisture. If traveling across time zones, adjust the timing of doses gradually as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with PCOS struggling to conceive for 2 years
She was prescribed this medicine by her fertility specialist. She took it for 5 days starting on day 5 of her cycle. After two cycles, she ovulated regularly and conceived. She reported mild hot flushes but no serious side effects.
💡 Lesson: Consistent use and monitoring can lead to successful ovulation and pregnancy.
👤 A 28-year-old man with low sperm motility
He was prescribed this medicine off-label to improve sperm quality. After 3 months, his sperm motility improved slightly, but he experienced mood swings. He discontinued after consulting his doctor.
💡 Lesson: Off-label use should be closely monitored, and side effects should be reported.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Ovulation usually occurs within 5 to 10 days after the last dose of this medicine in a cycle. It may take a few cycles to achieve pregnancy.

Q: Can I take this medicine without a prescription?

A: No, this medicine is a prescription drug and must only be taken under a doctor's supervision.

Q: What are the chances of having twins?

A: The chance of multiple pregnancy is increased compared to natural conception, but it is still relatively low. Discuss with your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver?
  • Can I drive after taking this medicine?
  • Does it interact with my other medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for clonin tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine guarantees pregnancy.
    Fact: It improves ovulation but does not guarantee pregnancy; many factors affect fertility.
  • Myth: It is safe to take without monitoring.
    Fact: It requires close medical supervision due to risks like ovarian hyperstimulation.

🔄 Alternative Options

Generic Alternatives

  • Clomiphene 50 mg tablet
  • Coenzyme Q10 50 mg capsule

📊 Comparison with Similar Medicines

[{"medicine":"Letrozole","difference":"Another ovulation inducer, often used in PCOS; may have fewer side effects."},{"medicine":"Gonadotropins","difference":"Injectable hormones that directly stimulate ovaries; used when clomiphene fails."}]

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