Clofert 50 Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or bloating
- Rapid weight gain over a few days
- Difficulty breathing or shortness of breath
- Blurred vision or double vision
- Yellowing of skin or eyes
- Chest pain or swelling in one leg
- Severe nausea and vomiting
If experiencing severe symptoms, call emergency services immediately.
What is clomi 50mg tablet used for?
This medicine is a 50 mg tablet used to treat infertility in women by inducing ovulation. It works by increasing hormones that stimulate the ovaries to release eggs.
- Generic Name: Clomiphene
- Manufacturer: West-Coast Pharmaceutical Works Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 clomi 50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोमिफीन 50 मिलीग्राम की गोली है, जिसका उपयोग महिलाओं में बांझपन के इलाज के लिए किया जाता है। यह अंडाशय को अंडे बनाने और छोड़ने के लिए उत्तेजित करती है। यह उन महिलाओं के लिए है जो नियमित रूप से ओव्यूलेट नहीं करती हैं। इसका सेवन डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में गर्म लहरें, पेट में दर्द या सूजन, मतली, सिरदर्द और स्तन में कोमलता शामिल हैं। कुछ महिलाओं को मूड स्विंग्स, चक्कर आना या दृष्टि में बदलाव हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम शामिल है, जिसमें तेज पेट दर्द, वजन बढ़ना और सांस लेने में कठिनाई हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप मात्रा न बढ़ाएं या घटाएं। आमतौर पर इसे मासिक धर्म चक्र के एक विशेष दिन से शुरू करके पांच दिनों तक लिया जाता है। नियमित अल्ट्रासाउंड और जांच करवाते रहें। अगर आपको चक्कर आना या दृष्टि में बदलाव महसूस हो, तो वाहन न चलाएं। गर्भवती होने पर इस दवा का सेवन न करें। इसे बच्चों की पहुंच से दूर रखें।
💊 clomi 50mg tablet Uses & Benefits
[{"condition":"Anovulatory infertility","description":"This medicine is used to induce ovulation in women who do not ovulate regularly, often due to polycystic ovary syndrome or other hormonal imbalances.","evidence":"Well-established"},{"condition":"Luteal phase defect","description":"Sometimes used to improve luteal phase progesterone production in women with short luteal phases.","evidence":"Limited"},{"condition":"Male hypogonadism","description":"Occasionally used off-label to stimulate testosterone production and improve sperm count in men with low gonadotropin levels.","evidence":"Limited"}]
Off-label uses: [{"condition":"Male infertility","description":"This medicine may be prescribed off-label to men with low sperm counts to improve sperm production, but evidence is limited and inconsistent.","evidence":"Limited"},{"condition":"Gynecomastia","description":"Rarely used off-label in men to treat breast enlargement, but not a standard treatment.","evidence":"Limited"}]
Primary treatment for: Anovulatory infertility
Also treats: Polycystic ovary syndrome, Luteal phase defect
📋 Drug Information
| Generic Name(s) | Clomiphene |
| Brand Name | Axifert 50mg Tablet |
| Manufacturer | West-Coast Pharmaceutical Works Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Partial estrogen agonist |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to estrogen receptors in the hypothalamus and pituitary gland. By blocking estrogen's negative feedback, it increases the release of gonadotropin-releasing hormone, which in turn raises follicle-stimulating hormone and luteinizing hormone levels. These hormones stimulate the ovaries to produce and release eggs.
Mechanism Steps
💡 How to Take clomi 50mg tablet
Strength: 50 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose is 50 mg once daily for 5 days, starting on the 5th day of the menstrual cycle. If ovulation does not occur, the dose may be increased to 100 mg daily for 5 days in the next cycle, as directed by your doctor. The maximum recommended dose is 100 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | This medicine is not intended for use in elderly women beyond reproductive age. No specific dosing recommendations. |
| Renal Impairment | No specific dose adjustment provided in the labeling. Use with caution in renal impairment. |
| Hepatic Impairment | Contraindicated in severe liver disease. Use with caution in mild to moderate impairment; dose adjustment may be needed. |
| Maximum Daily Dose | 100 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of clomi 50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Hormonal contraceptives | Major | |
| Tamoxifen | Major | |
| Fluoxetine | Moderate | |
| Paroxetine | Moderate | |
| Rifampin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Hormonal contraceptives
- Tamoxifen
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
- CYP2D6 inducers (e.g., rifampin)
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness and liver problems. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy","Liver disease","Unexplained abnormal vaginal bleeding","Ovarian cysts (except in PCOS)","Hypersensitivity to clomiphene"]
⚠️ Warnings & Precautions
["Use only under specialist supervision.","May cause visual disturbances; avoid driving if affected.","Risk of multiple pregnancies (twins, triplets).","May cause ovarian hyperstimulation syndrome.","Not for use in women with primary ovarian failure.","May increase risk of blood clots."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. It is not recommended for use during breastfeeding. Consult your doctor for guidance.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, abdominal pain, and visual disturbances. Seek immediate medical attention. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. This medicine is usually taken for five days starting on a specific day of your menstrual cycle, as directed by your clinician. You should have regular check-ups, including ultrasound scans, to monitor your ovarian response. Avoid driving or operating heavy machinery if you experience dizziness or visual disturbances. Do not take this medicine if you are pregnant or suspect you might be pregnant. Inform your doctor about all other medicines you are taking, especially hormonal treatments. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not intended for use in elderly women beyond reproductive age.
🤰 Pregnancy Planning (TTC)
This medicine is used to help you conceive. If you become pregnant, stop taking it immediately and consult your doctor for prenatal care.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine before any surgery, as it may affect blood clotting.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. No specific precautions, but maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but if you experience abdominal pain or bloating, reduce intensity. Consult your doctor before starting a new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or visual disturbances in some women. Avoid driving or operating heavy machinery if affected. Otherwise, it usually does not interfere with daily activities.
🛑 When to Stop This Medicine
Stop taking this medicine and contact your doctor immediately if you experience visual disturbances, severe abdominal pain, or signs of an allergic reaction. Do not stop without consulting your doctor if you are in the middle of a treatment cycle.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of ovarian cysts and possibly ovarian cancer, though evidence is inconclusive. Regular monitoring is advised. It is generally recommended to limit treatment to a few cycles if pregnancy does not occur.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another oral ovulation induction agent, often used as first-line for PCOS.
Evidence: Well-establishedInjectable hormones used for ovulation induction in specialist settings.
Evidence: Well-establishedCan restore ovulation in some women with PCOS.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. If traveling across time zones, continue taking it at the same interval as prescribed, but consult your doctor for specific advice. Store away from direct sunlight and moisture. Declare it at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Ovulation typically occurs 5 to 10 days after the last dose of a treatment cycle.
A: Yes, this medicine increases the chance of multiple pregnancies, including twins.
A: No, this medicine should not be taken if you are pregnant. Stop and inform your doctor immediately if you suspect pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for clomi 50mg tablet
View AllAlternative brands with exact same active ingredient:
-
StayHappi Clomiphene 50mg TabletSarvagunaushdhi Pvt Ltd ₹16.67 49.2% CHEAPER
-
clomiday 50mg tabletAuzalus Lifesciences ₹30.00 8.6% CHEAPER
-
ovuclom 50mg tabletVhb Life Sciences Inc ₹30.00 8.6% CHEAPER
-
clomisur 50mg tabletSurge Biotech Pvt Ltd ₹34.00 3.6% COSTLIER
-
maturova tabletNovartis India Ltd ₹35.16 7.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine guarantees pregnancy.
Fact: It increases the chance of ovulation but does not guarantee pregnancy. - Myth: This medicine is safe to take without monitoring.
Fact: Regular monitoring is essential to avoid complications like ovarian hyperstimulation.
🔄 Alternative Options
Generic Alternatives
- Clomiphene citrate 50 mg tablet
Brand Alternatives
- Clofert 50
- Fertyl 50
- Ovofar 50
- Siphene 50