aldigesic p 100mg/325mg tablet - Uses, Price, Side Effects & Substitutes
What is aldigesic p 100mg/325mg tablet used for?
Aldigesic P (Aceclofenac + Paracetamol) is used to treat PAIN ANALGESICS. It contains Aceclofenac (100mg) + Paracetamol (325mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paraceta. Always consult your doctor before use. Take as prescribed.
- Generic Name: Aceclofenac + Paracetamol
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ aldigesic p 100mg/325mg tablet Uses & Benefits
Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.
Off-label uses: Postoperative pain, migraine (limited evidence).
โ๏ธ Pros & Cons
Benefits
- โ Dard aur bukhar dono mein tez aaram milta hai.
- โ Ek tablet mein do dawai ka combination hai, isliye alag-alag dawai lene ki zaroorat nahi.
- โ Swelling aur inflammation bhi kam karta hai, jo gathiya aur chot mein faaydemand hai.
Drawbacks
- โ Pet mein jalan, ghasphat, ya ulcer ka khatra badha sakta hai, todo ise khana khaane ke baad lena chahiye.
- โ Liver aur kidney par zor pad sakta hai, isliye zyada din tak nahi lena chahiye.
- โ Kuch logon ko chakkar, neend aana, ya skin rash ho sakta hai.
๐ Drug Information
| Generic Name(s) | Aceclofenac + Paracetamol |
| Brand Name | Aldigesic P |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
Mechanism Steps
๐ก How to Take aldigesic p 100mg/325mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aldigesic p 100mg/325mg tablet
โ Common Side Effects
- Nausea
- Dizziness
- Drowsiness
- Rash
- GI upset
๐จ Serious Side Effects
- GI bleeding
- Hepatotoxicity
- Renal failure
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Anaphylaxis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels |
| Aspirin | Major | Increased risk of GI ulceration |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic efficacy |
| Anticoagulants | Moderate | Increased INR |
| SSRIs | Moderate | Increased bleeding risk |
| Antacids | Minor | Reduced absorption of aceclofenac |
| Cholestyramine | Minor | Reduced absorption of paracetamol |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- SSRIs
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid alcohol.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.
๐ Monitoring Parameters
Liver function tests, renal function, CBC, blood pressure.
๐คฑ Lactation Safety
Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.
Additional Safety Advice
Alcohol ke saath lena liver ke liye nuksaan-daayak hai, isliye bilkul na lein.
Pregnancy ke aakhri 3 mahine mein bilkul na lein; pehle 6 mahine mein doctor ki salah zaroori hai.
Isse chakkar ya neend aa sakti hai, isliye gadi chalane se pehle dhyan rakhein.
Liver ki bimari mein iska istemal na karein ya doctor se poochhein.
Kidney ki problem mein dose kam karna pad sakta hai, doctor se milein.
๐ Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
โ Frequently Asked Questions
Q: Can I take aldigesic p 100mg/325mg tablet on empty stomach?
A: Nahi, ise khali pet lene se pet mein jalan aur ghasphat ho sakti hai, isliye hamesha khana khaane ke baad lein.
Q: Is it safe during pregnancy?
A: Pregnancy ke aakhri 3 mahine mein ye tablet bilkul safe nahi hai. Pehle 6 mahine mein doctor ki salah lena zaroori hai.
Q: What if I miss a dose?
A: Agar dose miss ho jaye toh jaise yaad aaye, lekin agar agle dose ka time ho gaya hai toh chhoda diya karein. Ek baar mein do tablet na lein.
Q: Does it cause sleepiness or drowsiness?
A: Haan, kuch logon ko isse halki neend ya chakkar aa sakta hai, isliye gadi chalane ya machine chalane mein saavdhaani rahein.
Q: How long does it take to show results?
A: Ye tablet lene ke 30-60 minute ke andar dard aur bukhar mein kami aane lagti hai, aur asar 4-6 ghante tak rehta hai.