cirodome 1mg suspension - Uses, Price, Side Effects & Substitutes
What is cirodome 1mg suspension used for?
Actidom 5mg Oral Suspension (Domperidone) is used to treat GASTRO INTESTINAL. It contains Domperidone (1mg), which Domperidone is a dopamine D2 receptor antagonist that acts primarily in the chem. Always consult your doctor before use. Take as prescribed.
- Generic Name: Domperidone
- Manufacturer: Ciron Drugs & Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cirodome 1mg suspension Uses & Benefits
๐ Drug Information
| Generic Name(s) | Domperidone |
| Brand Name | Actidom 5mg Oral Suspension |
| Manufacturer | Ciron Drugs & Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Dopamine (D2) receptor antagonist-Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC). Protect from light and moisture. Keep bottle tightly closed. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Domperidone is a dopamine D2 receptor antagonist that acts primarily in the chemoreceptor trigger zone (CTZ) and gastrointestinal tract. It blocks dopamine receptors, increasing lower esophageal sphincter pressure, enhancing gastric motility and peristalsis, and accelerating gastric emptying.
Mechanism Steps
๐ก How to Take cirodome 1mg suspension
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cirodome 1mg suspension
โ Common Side Effects
- Dry mouth
- Headache
- Diarrhea
- Abdominal cramps
- Galactorrhea
- Gynecomastia
- Amenorrhea
๐จ Serious Side Effects
- QT prolongation
- Torsades de pointes
- Cardiac arrest
- Extrapyramidal symptoms (dystonia, akathisia)
- Neuroleptic malignant syndrome (rare)
โ ๏ธ Rare Side Effects
- Allergic reactions (rash, urticaria)
- Seizures
- Hepatotoxicity
- Leukopenia
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased risk of QT prolongation and cardiac arrhythmias |
| Erythromycin | Major | Increased risk of QT prolongation |
| Clarithromycin | Major | Increased risk of QT prolongation |
| Amiodarone | Major | Increased risk of QT prolongation |
| Quinidine | Major | Increased risk of QT prolongation |
| Fluconazole | Major | Increased risk of QT prolongation |
| Ritonavir | Major | Increased risk of QT prolongation |
| Saquinavir | Major | Increased risk of QT prolongation |
| Telaprevir | Major | Increased risk of QT prolongation |
| Voriconazole | Major | Increased risk of QT prolongation |
| Cimetidine | Moderate | Reduced absorption of domperidone |
| Ranitidine | Moderate | Reduced absorption of domperidone |
| Omeprazole | Moderate | Reduced absorption of domperidone |
| Phenothiazines | Moderate | Increased risk of extrapyramidal symptoms |
| Tricyclic antidepressants | Moderate | Increased risk of QT prolongation |
| SSRIs | Moderate | Increased risk of QT prolongation |
| MAOIs | Moderate | Increased risk of hypertensive crisis |
| Lithium | Moderate | Increased risk of extrapyramidal symptoms |
| Opioid analgesics | Moderate | Antagonism of gastrointestinal prokinetic effect |
| Anticholinergics | Moderate | Antagonism of gastrointestinal prokinetic effect |
| Aluminum-containing antacids | Minor | Reduced absorption of domperidone |
| Sucralfate | Minor | Reduced absorption of domperidone |
| Digoxin | Minor | Reduced absorption of digoxin |
| Paracetamol | Minor | No significant interaction |
| Diazepam | Minor | No significant interaction |
๐จ Major Interactions
- Ketoconazole
- Erythromycin
- Clarithromycin
- Amiodarone
- Quinidine
- Fluconazole
- Ritonavir
- Saquinavir
- Telaprevir
- Voriconazole
โก Moderate Interactions
- Cimetidine
- Ranitidine
- Omeprazole
- Phenothiazines
- Tricyclic antidepressants
- SSRIs
- MAOIs
- Lithium
- Opioid analgesics
- Anticholinergics
โน๏ธ Minor Interactions
- Aluminum-containing antacids
- Sucralfate
- Digoxin
- Paracetamol
- Diazepam
๐ฝ๏ธ Food Interactions
Food may reduce absorption; take 15-30 minutes before meals. Grapefruit juice may increase plasma levels.
๐ท Alcohol Interaction
Alcohol may enhance sedative effects and increase risk of extrapyramidal symptoms.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to domperidone; prolactinoma; gastrointestinal hemorrhage, obstruction, or perforation; moderate to severe hepatic impairment; known QT prolongation or concurrent use of QT-prolonging drugs.
๐ Monitoring Parameters
ECG for QT interval in patients at risk; renal function; signs of extrapyramidal symptoms; gastrointestinal symptoms.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution. May cause adverse effects in nursing infants.
๐ Overdose Management
Symptoms: drowsiness, disorientation, extrapyramidal reactions. Treatment: gastric lavage, activated charcoal, supportive care. Anticholinergic agents may be used for extrapyramidal symptoms.
โฐ Missed Dose
Take the missed dose as soon as remembered. If it is almost time for the next dose, skip the missed dose. Do not double the dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cirodome 1mg suspension
View AllAlternative brands with exact same active ingredient (Domperidone (1mg)):
-
domiron suspensionAcron Pharmaceuticals โน19.69 11% CHEAPER
-
domact 1mg suspensionBindlysh Biotec Ltd โน20.34 8.1% CHEAPER
-
domedon suspensionAlpic Remedies Ltd โน20.63 6.8% CHEAPER
-
domdon suspensionMaitri Healthcare Pvt Ltd โน21.09 4.7% CHEAPER
-
dompon 1mg oral suspensionFinecure Pharmaceuticals Ltd. โน23.00 3.9% COSTLIER
-
motimin 1mg tabletMDC Pharmaceuticals Pvt Ltd โน23.75 7.3% COSTLIER
-
cadom syrupCasca Remedies Pvt Ltd โน24.00 8.5% COSTLIER
-
casdom oral dropsCasca Remedies Pvt Ltd โน24.00 8.5% COSTLIER
-
domsettler suspensionLifeon Paediatrics Ltd โน24.95 12.7% COSTLIER
-
denosia suspensionKontest Chemicals Ltd โน25.53 15.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.