cinkona 300mg injection - Quinine (300mg) medicine

cinkona 300mg injection

4.8 (11 reviews)
๐Ÿญ Ipca Laboratories Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is cinkona 300mg injection used for?

Arm Q Injection (Quinine) is used to treat ANTI MALARIALS. It contains Quinine (300mg), which Interferes with heme polymerization in the parasite's digestive vacuole, le. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Quinine
  • Manufacturer: Ipca Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cinkona 300mg injection Uses & Benefits

Treatment of uncomplicated and severe falciparum malaria; nocturnal leg cramps (off-label).

Off-label uses: Nocturnal leg cramps, Babesiosis (with clindamycin)

๐Ÿ“‹ Drug Information

Generic Name(s)Quinine
Brand NameArm Q Injection
ManufacturerIpca Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI MALARIALS
Action ClassAntimalarial- others
Route of AdministrationIntramuscular injection.
StorageStore at 20-25ยฐC; protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular injection.
DistributionWidely distributed throughout body tissues, including brain and placenta.
Protein BindingApproximately 70-90% bound to plasma proteins.
MetabolismPrimarily hepatic via CYP3A4 and CYP2C19.
Half-Life8-14 hours in healthy adults; prolonged in severe malaria or hepatic impairment.
ExcretionRenal (20% unchanged); also biliary.
Bioavailability100% (intramuscular).
Onset of ActionRapid (within 1-2 hours).
Peak Plasma Time1-3 hours after intramuscular injection.
Duration of ActionApproximately 8-12 hours.

How It Works

Interferes with heme polymerization in the parasite's digestive vacuole, leading to toxic heme accumulation.

Mechanism Steps

1Quinine enters the parasite's food vacuole.
2It inhibits heme polymerase, preventing heme detoxification.
3Accumulation of toxic heme damages the parasite membrane.

๐Ÿ’ก How to Take cinkona 300mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cinkona 300mg injection

โœ… Common Side Effects

  • Cinchonism (tinnitus, headache, nausea, blurred vision)
  • Hypoglycemia
  • QT prolongation

๐Ÿšจ Serious Side Effects

  • Cardiac arrhythmias
  • Severe hypoglycemia
  • Hemolytic anemia (G6PD deficiency)
  • Thrombocytopenia

โš ๏ธ Rare Side Effects

  • Blackwater fever
  • Photosensitivity
  • Hepatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Amiodarone Major Increased risk of cardiotoxicity (QT prolongation)
Digoxin Major Increased digoxin levels and toxicity
Mefloquine Major Increased risk of seizures and cardiac effects
Halofantrine Major Increased risk of QT prolongation

๐Ÿšจ Major Interactions

  • Warfarin
  • Amiodarone
  • Digoxin
  • Mefloquine
  • Halofantrine

โšก Moderate Interactions

  • Cimetidine
  • Rifampin
  • Phenytoin
  • Carbamazepine

โ„น๏ธ Minor Interactions

  • Aluminum-containing antacids
  • Calcium channel blockers

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase quinine levels.

๐Ÿท Alcohol Interaction

May increase risk of CNS depression and hepatotoxicity.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to quinine; G6PD deficiency; optic neuritis; tinnitus; history of QT prolongation.

๐Ÿ“Š Monitoring Parameters

ECG (QT interval), blood glucose, renal function, auditory and visual function.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

Supportive care; monitor ECG, electrolytes; consider activated charcoal if oral; hemodialysis ineffective.

โฐ Missed Dose

Administer as soon as remembered; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cinkona 300mg injection

View All

Alternative brands with exact same active ingredient (Quinine (300mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

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