Arsufee Kit 100mg/500mg (Artesunate + Sulphadoxine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing, throat tightness, or swelling of the face, lips, or tongue.
- A spreading, painful skin rash with blisters, peeling, or sores in the mouth or eyes.
- Yellowing of the eyes or skin, dark urine, or pale stools.
- Severe abdominal pain, persistent vomiting, or inability to keep fluids down.
- Unusual bleeding, bruising, or blood in vomit or stool.
- High fever that does not settle within 48 to 72 hours of starting treatment.
- Confusion, drowsiness, seizures, or loss of consciousness.
- Very low urine output or swelling of the legs and feet.
If experiencing severe symptoms, call emergency services immediately.
What is arsufee kit 100mg/500mg/25mg kit used for?
This medicine is an artemisinin-based combination antimalarial kit containing artesunate 100 mg and sulphadoxine 500 mg. It is used to treat confirmed uncomplicated Plasmodium falciparum malaria in adults and children, usually as a short supervised course. It works by killing malaria parasites in the blood through two different mechanisms. It should not be used for malaria prevention, for severe malaria, or without a confirmed diagnosis, and it must be taken exactly as prescribed.
- Generic Name: Artesunate (100mg) + Sulphadoxine (500mg)
- Manufacturer: Staunch Health Care Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 arsufee kit 100mg/500mg/25mg kit के बारे में (Hindi Summary)
उपयोग: यह दवा मलेरिया के इलाज के लिए इस्तेमाल की जाने वाली एक संयोजन दवा है, जिसमें आर्टेसुनेट 100 मिलीग्राम और सल्फाडॉक्सिन 500 मिलीग्राम होते हैं। यह मुख्य रूप से प्लास्मोडियम फाल्सीपेरम मलेरिया के इलाज के लिए दी जाती है, जिसे खून की जांच से पहले पुष्टि करना जरूरी है। यह दवा मलेरिया के परजीवियों को खून में मारती है, जिससे बुखार, ठंड लगना, सिरदर्द और शरीर दर्द जैसे लक्षण कम होने लगते हैं। इसे डॉक्टर के बताए अनुसार पूरा कोर्स करना बहुत जरूरी है, भले ही बुखार उतर जाए। यह दवा मलेरिया से बचाव के लिए नहीं है और गंभीर मलेरिया में अलग इलाज की जरूरत होती है। गर्भवती महिलाओं, छोटे बच्चों, किडनी या लिवर की बीमारी वाले मरीजों को यह दवा डॉक्टर की सलाह के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा को लेने पर आमतौर पर मतली, उल्टी, पेट दर्द, भूख कम लगना, सिरदर्द, चक्कर आना और हल्की त्वचा पर चकत्ते जैसी समस्याएं हो सकती हैं। कुछ लोगों को थकान, दस्त या खुजली भी महसूस हो सकती है। गंभीर लेकिन दुर्लभ मामलों में चेहरे, होंठ या गले में सूजन, सांस लेने में तकलीफ, त्वचा पर फफोले पड़ना, आंखों या त्वचा का पीला पड़ना, गहरे रंग का पेशाब, असामान्य रक्तस्राव या बहुत तेज पेट दर्द हो सकता है। अगर ऐसा कुछ भी हो, तो दवा तुरंत बंद करें और डॉक्टर से मिलें। बिना डॉक्टर की सलाह के दवा दोबारा शुरू न करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और पूरा कोर्स पूरा करें, चाहे बुखार उतर जाए। दवा को भोजन के साथ और भरपूर पानी के साथ लें, जिससे पेट की तकलीफ कम हो। इस दवा को किसी और के साथ साझा न करें। इलाज के दौरान शराब न पिएं, क्योंकि इससे मतली, चक्कर और लिवर पर दबाव बढ़ सकता है। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर खून पतला करने वाली दवाएं, मधुमेह की दवाएं, दौरे की दवाएं और अन्य मलेरिया की दवाएं। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को जरूर बताएं। दवा को बच्चों से दूर, ठंडी और सूखी जगह पर रखें। बिना जांच के बुखार में इस दवा का इस्तेमाल न करें।
💊 arsufee kit 100mg/500mg/25mg kit Uses & Benefits
[{"condition":"Uncomplicated Plasmodium falciparum malaria","description":"This medicine is used to treat confirmed uncomplicated falciparum malaria in adults and children, helping to clear parasites from the blood and relieve fever, chills, and body aches.","evidence":"Well-established"},{"condition":"Mixed malaria infection with Plasmodium falciparum","description":"It may be used when laboratory tests show a mixed infection that includes Plasmodium falciparum, because the artesunate component acts rapidly against blood-stage parasites.","evidence":"Moderate"},{"condition":"Malaria in areas with sulfadoxine-sensitive parasites","description":"In regions where local malaria parasites remain sensitive to sulphadoxine, this combination can provide effective treatment when used according to national guidelines.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Malaria prevention in special situations","description":"This medicine is not approved for malaria prevention, and it should not be used for prophylaxis except in rare situations under strict specialist supervision.","evidence":"Limited"},{"condition":"Non-falciparum malaria","description":"It is not a first-choice treatment for Plasmodium vivax, ovale, or malariae infections, and any such use would be off-label and guided by local resistance patterns.","evidence":"Limited"}]
Primary treatment for: Uncomplicated Plasmodium falciparum malaria
Also treats: Mixed malaria infection including Plasmodium falciparum, Malaria in patients living in areas with sulfadoxine-sensitive parasites
📋 Drug Information
| Generic Name(s) | Artesunate (100mg) + Sulphadoxine (500mg) |
| Brand Name | arsufee kit 100mg/500mg/25mg kit |
| Manufacturer | Staunch Health Care Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, ideally between 15°C and 30°C, in a cool, dry place. Keep it in the original packaging, away from direct sunlight, heat, and moisture. Do not store it in the bathroom or near the kitchen stove. Keep all medicines out of the reach of children and pets. |
| Shelf Life | The shelf life is usually 24 to 36 months from the date of manufacture when stored as directed. Always check the expiry date printed on the pack before use. Do not use the medicine after the expiry date, and dispose of expired medicines safely according to local guidelines. |
| WHO Guideline | The World Health Organization recommends artemisinin-based combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria. The choice of specific combination depends on local resistance patterns and national treatment policy. This medicine should be used only where sulphadoxine-containing combinations remain effective and according to national malaria guidelines. |
| ICMR Guideline | The Indian Council of Medical Research and the National Vector Borne Disease Control Programme provide national guidelines for malaria diagnosis and treatment in India. These guidelines recommend confirming malaria with a blood test and using artemisinin-based combination therapy for uncomplicated falciparum malaria according to the latest national policy. Clinicians should follow the current national guideline because recommended combinations may change with resistance patterns. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antimalarial medicines that attack the malaria parasite in different ways. Artesunate is converted in the body to dihydroartemisinin, which reacts with iron inside the parasite to produce harmful free radicals that damage parasite proteins and membranes, leading to rapid parasite death. Sulphadoxine blocks an enzyme called dihydropteroate synthase that the parasite needs to make folate and nucleic acids, which stops the parasite from growing and multiplying. Together, the fast-acting artesunate quickly reduces the number of parasites in the blood, while sulphadoxine provides a longer-lasting second attack that helps clear remaining parasites and lowers the risk of treatment failure.
Mechanism Steps
💡 How to Take arsufee kit 100mg/500mg/25mg kit
Strength: This medicine is supplied as an immediate-release oral kit containing artesunate 100 mg and sulphadoxine 500 mg. The kit may include separate tablets or a fixed combination, and the exact number of units per dose is printed on the packaging and prescribed by the doctor.
Dosage Information
| Adult Dosage | The adult dose of this medicine depends on the confirmed type of malaria, the patient's weight, and national treatment guidelines. It is usually given as a supervised course over one to three days, with the artesunate and sulphadoxine components taken together as directed on the kit. The exact number of tablets per dose and the number of doses must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose yourself, and do not stop early even if symptoms improve. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific kit. Children with malaria should be treated by a pediatrician or under national malaria program guidance, because dosing depends on weight, age, and the exact formulation used. Never give this medicine to a child without a doctor's prescription and clear instructions. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially nausea, dizziness, skin reactions, and blood or liver changes. The dose is generally the same as for younger adults, but a clinician should review kidney and liver function, other medicines, and hydration status before treatment. Elderly patients should be monitored closely during the course. |
| Renal Impairment | Patients with kidney disease may need a modified dose or an alternative antimalarial, because sulphadoxine is cleared mainly by the kidneys. Kidney function should be checked before treatment when possible, and the dose must be individualized by a qualified clinician based on renal function. Staying well hydrated is important during treatment. |
| Hepatic Impairment | Patients with liver disease should use this medicine only under medical supervision, because both artesunate and sulphadoxine are processed by the liver. Liver function may need to be checked before and during treatment. The dose must be individualized by a qualified clinician based on hepatic function, and warning signs of liver injury should be monitored closely. |
| Maximum Daily Dose | The maximum daily dose must be determined by a qualified clinician according to the confirmed diagnosis, patient weight, and national malaria treatment guidelines. Do not exceed the dose prescribed on the kit or by your doctor. Taking more than the recommended dose increases the risk of serious side effects without improving cure. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of arsufee kit 100mg/500mg/25mg kit
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Phenytoin | Major | |
| Glibenclamide | Major | |
| Other antimalarials | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| Oral contraceptives | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin and other blood thinners
- Methotrexate
- Phenytoin
- Sulfonylureas such as glibenclamide
- Other antimalarials such as chloroquine or mefloquine
⚡ Moderate Interactions
- ACE inhibitors and angiotensin receptor blockers
- Diuretics
- Corticosteroids
- Oral contraceptives
- Live vaccines such as oral typhoid vaccine
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can worsen nausea, vomiting, dizziness, and dehydration, and it adds extra stress to the liver while the body is processing both the antimalarial medicines and the infection. Avoiding alcohol also helps you recognise side effects more clearly and supports faster recovery from malaria.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or severe reaction to artesunate, sulphadoxine, or any other sulfonamide medicine.","Previous serious skin reaction such as Stevens-Johnson syndrome or toxic epidermal necrolysis after taking a sulfonamide.","Severe or complicated malaria that requires injectable or intensive hospital treatment.","Use as malaria prevention or self-treatment without a confirmed diagnosis.","Pregnancy, unless specifically advised by a qualified clinician after weighing the risks and benefits.","Infants below the age recommended by national malaria treatment guidelines.","Severe liver or kidney disease, unless supervised by a specialist."]
⚠️ Warnings & Precautions
["Confirm malaria with a blood test before taking this medicine, because fever can have many other causes.","Complete the full prescribed course even if you feel better, to prevent parasite regrowth and resistance.","Stop the medicine and seek urgent care if you develop a spreading rash, blisters, facial swelling, or difficulty breathing.","Tell your doctor about all other medicines, especially blood thinners, diabetes medicines, seizure medicines, and other antimalarials.","Use effective contraception during treatment and for a short period afterwards if you are of childbearing potential.","Avoid alcohol and stay well hydrated to reduce stomach upset and liver stress.","Do not share this medicine with family members or friends, even if they have similar symptoms.","Keep the kit in its original packaging and out of reach of children."]
🤱 Lactation Safety
Both artesunate and sulphadoxine can pass into breast milk. Sulphadoxine may be present in breast milk for several days after the last dose. Breastfeeding should be discussed with a doctor before starting this medicine. In many cases, breastfeeding may continue while the mother is treated, but the baby should be watched for rash, jaundice, or poor feeding, and medical advice should be sought if any of these occur.
💊 Overdose Management
Overdose with this medicine can increase the risk of nausea, vomiting, dizziness, skin reactions, blood problems, and liver or kidney injury. If you suspect an overdose, stop taking the medicine and seek immediate medical care at the nearest hospital. Take the original kit or packaging with you so that the treating team knows exactly what was taken. Treatment is supportive and may include monitoring of blood counts, liver and kidney function, and management of any allergic or skin reactions. Do not try to induce vomiting unless a healthcare professional advises it.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided it is not almost time for the next dose. If it is nearly time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you vomit within 30 minutes of taking a dose, tell your doctor, because the dose may need to be repeated. Completing the full course is important to clear the malaria infection properly.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor and complete the full course even if you feel better after the first dose. Swallow the tablets with plenty of water and take them with food to reduce stomach upset. Do not share this medicine with anyone else, even if they have similar symptoms. Avoid alcohol while taking this medicine because it can worsen nausea, dizziness, and liver stress. Inform your doctor about all other medicines you take, especially blood thinners, diabetes medicines, seizure medicines, and other antimalarials. Use effective contraception during treatment if you are of childbearing potential, and tell your doctor immediately if you are pregnant or breastfeeding. Keep the kit out of reach of children and store it in a cool, dry place away from direct sunlight. Do not use this medicine for malaria prevention or for self-treatment of fever without a confirmed diagnosis.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more likely to experience dizziness, nausea, dehydration, and blood or liver changes while taking this medicine. They should be monitored closely, especially if they have heart, kidney, liver, or blood-related conditions. Hydration and nutrition are particularly important. A clinician should review all other medicines to avoid interactions before starting treatment.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss malaria prevention and treatment options with your doctor before conception. This medicine is not recommended during pregnancy unless a specialist decides it is necessary. Use effective contraception during treatment and for a short period afterwards if you are of childbearing potential. If you become pregnant while taking this medicine, contact your doctor immediately for advice.
🏥 Post-Surgery Considerations
If you have recently had surgery, tell your surgeon and anaesthetist about this medicine before any procedure. Malaria itself can increase the risk of complications after surgery, and some antimalarials can interact with anaesthetic or pain medicines. Your treating team will decide whether the course should be completed before surgery or whether an alternative antimalarial is needed.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. There is no major interaction with common dental anaesthetics, but if you have a bleeding disorder, are taking blood thinners, or have liver or kidney problems, your dentist may need to take extra precautions. Good hydration and completing your malaria treatment are important before undergoing elective dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while you have fever and are recovering from malaria. Light activity such as short walks may be fine if you feel up to it, but rest is more important during the acute phase. Drink enough water before, during, and after any activity. Return to your normal exercise routine gradually after your fever has settled and your doctor confirms you are recovering well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Malaria and its treatment can cause tiredness, dizziness, and difficulty concentrating, so avoid driving or operating heavy machinery until you feel fully alert. Most people need a few days of rest at home during treatment. Inform your employer or school about your illness and follow your doctor's advice about when to return to work or studies. If your job involves safety-sensitive tasks, wait until your doctor confirms that you have recovered.
🛑 When to Stop This Medicine
Do not stop this medicine early unless your doctor tells you to. Complete the full prescribed course even if you feel better. Stop the medicine immediately and seek medical help if you develop a serious allergic reaction, a spreading skin rash with blisters, yellowing of the eyes or skin, severe abdominal pain, unusual bleeding, or difficulty breathing. If you need to stop for any other reason, contact your doctor so that an alternative treatment can be arranged.
📅 Long-Term Use Effects
This medicine is usually taken for a short course, so long-term effects are uncommon when it is used correctly. Rarely, sulphadoxine can cause blood, liver, kidney, or skin problems that may appear during or shortly after treatment. If you have repeated courses of antimalarials over time, your doctor may check your blood counts, liver function, and kidney function. Long-term use without medical supervision is not recommended and can increase the risk of side effects and parasite resistance.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Alternatives such as artemether-lumefantrine or dihydroartemisinin-piperaquine may be used depending on local resistance patterns and national guidelines.
Evidence: Well-establishedSevere or complicated malaria requires hospital treatment with injectable antimalarials rather than this oral kit.
Evidence: Well-establishedUsing bed nets, repellents, and protective clothing helps prevent new malaria infections and supports overall malaria control.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines, such as oral typhoid vaccine, may be less effective during antimalarial treatment. If you need a live vaccine, discuss the timing with your doctor and usually wait until after the malaria treatment course is completed. Inactivated vaccines are generally not affected by this medicine, but always inform the vaccination team about your recent illness and treatment.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless the label specifically says so.
✅ DO
Keep the kit in its original packaging with the label intact.
❌ DON'T
Do not transfer tablets to unmarked containers.
✅ DO
Keep away from direct sunlight, heat, and moisture.
❌ DON'T
Do not store in the bathroom or near the kitchen stove.
✅ DO
Keep out of the reach of children and pets.
❌ DON'T
Do not use after the expiry date printed on the pack.
✈️ Traveling with This Medicine
If you are travelling with this medicine, carry it in its original packaging with the prescription copy and a doctor's note explaining that it is for malaria treatment. Keep it in your hand luggage so it stays at room temperature and does not get lost. Check the expiry date before travel and carry enough for the full course. If you are crossing time zones, ask your doctor whether the dose timing needs to be adjusted. Follow local customs rules for carrying prescription medicines, and keep a list of your other medicines and allergies with you at all times.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The artesunate component starts reducing parasites within hours, and fever often begins to settle within 24 to 48 hours. However, you must complete the full prescribed course to clear the infection properly.
A: No. Stopping early can allow surviving parasites to regrow and cause a relapse. Always complete the full course prescribed by your doctor.
A: If you vomit within 30 minutes of taking a dose, contact your doctor. The dose may need to be repeated, but only on medical advice.
A: This medicine is not recommended in pregnancy unless a qualified clinician decides that the benefit clearly outweighs the risk. Pregnant women with malaria need urgent specialist care.
A: Do not combine antimalarials unless a malaria specialist has specifically prescribed the combination, because some combinations can increase toxicity or heart rhythm problems.
A: Seek urgent care for difficulty breathing, facial swelling, spreading skin rash with blisters, yellow eyes or skin, severe abdominal pain, unusual bleeding, confusion, or very low urine output.
🤔 Common Patient Concerns
🔄 Substitutes for arsufee kit 100mg/500mg/25mg kit
View AllAlternative brands with exact same active ingredient:
-
Rtsunate SP 100mg/500mg/25mg TabletThemis Medicare Ltd ₹107.14 14.3% CHEAPER
-
Falciden KitWelgenic Pharma ₹140.63 12.5% COSTLIER
-
Rtrit-SP 100 CombikitUniventis Medicare Ltd ₹145.00 16% COSTLIER
-
arh plus kitLincoln Pharmaceuticals Ltd ₹155.53 24.4% COSTLIER
-
larinate 100 kitIpca Laboratories Ltd ₹164.06 31.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any fever.
Fact: This medicine treats malaria only. Fever has many causes, and taking antimalarials without a confirmed diagnosis can delay correct treatment and increase resistance. - Myth: You can stop the medicine once the fever goes away.
Fact: The full course must be completed even if you feel better, because stopping early can allow surviving parasites to regrow and cause relapse. - Myth: This medicine can be used to prevent malaria before travel.
Fact: This medicine is for treatment, not prevention. Malaria prevention requires different medicines and advice from a travel medicine specialist. - Myth: More tablets will cure malaria faster.
Fact: Taking more than the prescribed dose does not cure malaria faster and can cause serious side effects. Always follow the prescribed dose. - Myth: Antimalarials are safe to share with family members.
Fact: This medicine should never be shared. Each person needs a proper diagnosis and a dose based on their own weight, age, and health status.
🔄 Alternative Options
Generic Alternatives
- Artesunate and sulphadoxine combination kit
Brand Alternatives
- Arsufee Kit 100mg/500mg/25mg Kit