Chlorpromazine 50mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- High fever with muscle rigidity and confusion
- Involuntary movements of the face, tongue, or limbs
- Severe dizziness or fainting
- Palpitations or irregular heartbeat
- Yellowing of skin or eyes
- Unusual bruising or bleeding
- Difficulty breathing or swallowing
- Prolonged erection
If experiencing severe symptoms, call emergency services immediately.
What is chlorotame 50mg tablet used for?
Chlorpromazine 50 mg tablet is a typical antipsychotic used to treat schizophrenia, bipolar mania, and severe agitation. It works by blocking dopamine receptors in the brain. It is taken orally, usually 1-4 times daily, and must be prescribed and monitored by a doctor.
- Generic Name: Chlorpromazine
- Manufacturer: Triko Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 chlorotame 50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरप्रोमाज़ीन 50 मिलीग्राम की गोली है, जिसका उपयोग मानसिक विकारों जैसे सिज़ोफ्रेनिया, बाइपोलर डिसऑर्डर के मैनिक चरण, और गंभीर आंदोलन या आक्रामकता के इलाज के लिए किया जाता है। यह मतली और उल्टी को रोकने में भी मदद करती है। यह दवा मस्तिष्क में डोपामिन नामक रसायन को संतुलित करके काम करती है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, धुंधली दृष्टि, कब्ज, और वजन बढ़ना शामिल हैं। गंभीर दुष्प्रभावों में दिल की धड़कन में गड़बड़ी, बहुत कम रक्तचाप, और टार्डिव डिस्किनेसिया जैसी अनैच्छिक हरकतें शामिल हैं। न्यूरोलेप्टिक मैलिग्नेंट सिंड्रोम एक दुर्लभ लेकिन जानलेवा प्रतिक्रिया है। कोई भी गंभीर लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें। शराब और अन्य नींद लाने वाली दवाओं से बचें। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है। नियमित रूप से रक्तचाप, हृदय, और यकृत की जाँच कराएँ। धूप से बचाव करें। गर्भवती या स्तनपान कराने वाली महिलाएँ डॉक्टर से सलाह लें।
💊 chlorotame 50mg tablet Uses & Benefits
[{"condition":"Schizophrenia","description":"Helps reduce hallucinations, delusions, and disorganized thinking in patients with schizophrenia.","evidence":"Well-established"},{"condition":"Bipolar disorder (manic phase)","description":"Used to control acute mania and agitation in bipolar disorder.","evidence":"Well-established"},{"condition":"Severe agitation and aggression","description":"Short-term management of severe agitation or aggression in psychiatric emergencies.","evidence":"Well-established"},{"condition":"Nausea and vomiting","description":"Used for severe nausea and vomiting when other treatments are not effective.","evidence":"Well-established"},{"condition":"Intractable hiccups","description":"May be used for persistent hiccups that do not respond to other treatments.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Anxiety disorders","description":"Occasionally used for severe anxiety when other treatments fail, but not a first-line option.","evidence":"Limited"},{"condition":"Porphyria","description":"May be used in acute porphyria to control symptoms, but specialist supervision is required.","evidence":"Limited"}]
Primary treatment for: Schizophrenia
Also treats: Bipolar disorder, Severe agitation, Nausea and vomiting, Intractable hiccups
📋 Drug Information
| Generic Name(s) | Chlorpromazine |
| Brand Name | Chlorpromazine 50mg Tablet |
| Manufacturer | Triko Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Typical Antipsychotics |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture, heat, and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking dopamine D2 receptors in the brain, which helps reduce psychotic symptoms. It also blocks serotonin, histamine, and muscarinic receptors, contributing to its sedative and antiemetic effects.
Mechanism Steps
💡 How to Take chlorotame 50mg tablet
Strength: Chlorpromazine 50 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose for psychiatric conditions ranges from 25 mg to 100 mg taken 1 to 4 times daily, depending on the condition and response. For nausea and vomiting, a lower dose may be used. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the effects of this medicine, especially drowsiness, low blood pressure, and extrapyramidal symptoms. Start with a lower dose and titrate slowly. Regular monitoring is essential. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. Use with caution and monitor closely. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose reduction may be necessary. Regular liver function tests are recommended. |
| Maximum Daily Dose | The maximum daily dose is not established from available information. Doses up to 1000 mg per day have been used in some severe cases under close supervision, but this must be determined by a specialist. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of chlorotame 50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | |
| Fluoxetine | Moderate | |
| Carbamazepine | Moderate | |
| Ritonavir | Major | |
| Clozapine | Major | |
| Haloperidol | Major | |
| Morphine | Major | |
| Phenytoin | Moderate | |
| Prochlorperazine | Moderate | |
| Tramadol | Moderate |
🚨 Major Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)
- Anticholinergic drugs (e.g., benztropine, diphenhydramine)
- Levodopa
- Epinephrine
⚡ Moderate Interactions
- Antihypertensive drugs
- Lithium
- Metoclopramide
- Propranolol
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and the risk of severe low blood pressure. It can also worsen the sedative effects and impair your ability to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpromazine or other phenothiazines","Severe heart disease or recent heart attack","Severe liver disease","Parkinson's disease","Bone marrow depression","Coma or severe CNS depression","Breastfeeding"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","May cause low blood pressure; rise slowly from sitting or lying positions.","May cause QT prolongation; tell your doctor if you have heart problems.","May cause tardive dyskinesia with long-term use; report any involuntary movements.","May cause neuroleptic malignant syndrome; seek emergency care for high fever, muscle rigidity, or confusion.","May increase sensitivity to sunlight; use sunscreen and protective clothing.","May cause blood disorders; report fever, sore throat, or unusual bruising.","May cause liver problems; report yellowing of skin or eyes.","Use with caution in elderly patients with dementia; increased risk of death.","Do not stop suddenly; withdrawal symptoms may occur."]
🤱 Lactation Safety
Chlorpromazine is excreted in breast milk. Breastfeeding is not recommended while taking this medicine due to potential serious adverse effects in the infant. Consult your doctor for alternative options.
💊 Overdose Management
Overdose of chlorpromazine can cause severe drowsiness, coma, low blood pressure, abnormal heart rhythms, and seizures. Seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal, intravenous fluids, and medications to control seizures and heart rhythm. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop suddenly, as withdrawal symptoms may occur. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness. Avoid alcohol and other central nervous system depressants because they can increase drowsiness and low blood pressure. Tell your doctor about all other medicines you take, including over-the-counter drugs and herbal supplements. This medicine can make your skin more sensitive to sunlight, so use sunscreen and protective clothing. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor about the risks and benefits. Keep all appointments for monitoring, including blood tests and heart checks. Store this medicine at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of chlorpromazine, especially drowsiness, low blood pressure, and extrapyramidal symptoms. There is an increased risk of death when used in elderly patients with dementia-related psychosis. Use with caution and start with a lower dose.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Use effective contraception while on this medicine. Discuss the risks and benefits with your doctor.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and increase the risk of low blood pressure and sedation. Your doctor may adjust the dose before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It can cause dry mouth, which may increase the risk of dental problems. It may also interact with local anesthetics and sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, which may affect your ability to exercise safely. Avoid activities that require alertness, such as heavy lifting or high-intensity workouts, until you know how it affects you. Stay hydrated and rise slowly to prevent dizziness.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and blurred vision, which may affect your ability to drive, operate machinery, or perform tasks requiring alertness. Avoid these activities until you know how it affects you. It may also cause weight gain and metabolic changes, which can impact overall health. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Abrupt discontinuation can cause withdrawal symptoms such as nausea, vomiting, insomnia, and agitation, and may lead to relapse of the underlying condition. Your doctor will gradually taper the dose if discontinuation is necessary.
📅 Long-Term Use Effects
Long-term use of chlorpromazine may lead to tardive dyskinesia, a potentially irreversible movement disorder. It can also cause weight gain, metabolic changes, and eye changes. Regular monitoring of weight, blood sugar, lipids, and eye exams is recommended. Periodic blood tests and ECG may be needed. The dose should be reviewed regularly to ensure it is the lowest effective amount.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for schizophrenia and bipolar disorder.
Evidence: Well-establishedHelps support patients and families in managing mental illness.
Evidence: Well-establishedRegular exercise, healthy diet, and sleep hygiene can improve overall well-being.
Evidence: Emerging💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any vaccine while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the timing of doses. Check local customs regulations for controlled substances before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Sedation and antipsychotic effects may begin within 30-60 minutes, but full therapeutic effects may take several days to weeks.
A: No, do not stop suddenly. Always consult your doctor before stopping, as withdrawal symptoms and relapse can occur.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: No, avoid alcohol as it can increase drowsiness, dizziness, and low blood pressure.
A: Consult your doctor. Use only if clearly needed and under medical supervision. Human data are limited.
🤔 Common Patient Concerns
🔄 Substitutes for chlorotame 50mg tablet
View AllAlternative brands with exact same active ingredient:
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clozine 50mg tabletPsychotropics India Ltd ₹3.52 75.7% CHEAPER
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prozine 50mg tabletShine Pharmaceuticals Ltd ₹3.72 74.3% CHEAPER
-
chlorpro 50mg tabletPsycormedies ₹3.75 74.1% CHEAPER
-
ostil 50mg tabletOsho Pharma Pvt Ltd ₹3.75 74.1% CHEAPER
-
Trytil 50mg TabletS P Pharma ₹3.86 73.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Chlorpromazine is only for severe mental illness.
Fact: It is also used for severe nausea and vomiting, and for intractable hiccups. - Myth: You can stop taking chlorpromazine once you feel better.
Fact: Stopping suddenly can cause withdrawal symptoms and relapse. Always taper under medical supervision. - Myth: Chlorpromazine is addictive.
Fact: It is not addictive in the traditional sense, but it can cause dependence and withdrawal symptoms if stopped abruptly.
🔄 Alternative Options
Generic Alternatives
- Chlorpromazine 50 mg tablet (generic)
Brand Alternatives
- Chlorpromazine 50 mg tablet (various manufacturers)