Ageflux OLX Capsule SR: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or persistent vomiting
- Chest pain, palpitations, or difficulty breathing
- Uncontrolled muscle spasms, tremors, or rigidity
- Swelling of face, lips, tongue, or throat
- Yellowing of skin or eyes, dark urine
- Severe diarrhea with fever or blood
- Decreased urine output or swelling in legs
If experiencing severe symptoms, call emergency services immediately.
What is cforge l 75mg/40mg capsule used for?
This medicine is a combination of Levosulpiride 75 mg and Esomeprazole 40 mg used to treat acid reflux and dyspepsia. It works by reducing stomach acid and improving gastric emptying. It is taken once daily on an empty stomach.
- Generic Name: Levosulpiride + Esomeprazole
- Manufacturer: Medocean Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cforge l 75mg/40mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोसल्पिराइड 75 मिलीग्राम और एसोमेप्राजोल 40 मिलीग्राम का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, गैस्ट्रोएसोफेजियल रिफ्लक्स डिजीज (GERD), और अपच जैसी समस्याओं के इलाज के लिए किया जाता है। यह पेट में एसिड का उत्पादन कम करती है और पेट खाली होने की प्रक्रिया को तेज करती है, जिससे जलन, खट्टी डकार, और पेट भारी लगने जैसे लक्षणों में राहत मिलती है। यह दवा खाली पेट लेनी चाहिए, आमतौर पर सुबह नाश्ते से 30-60 मिनट पहले। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, मतली, दस्त, पेट दर्द, और मुँह सूखना शामिल हैं। ये आमतौर पर हल्के होते हैं और शरीर के सामान्य होने पर ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें कंपन, अकड़न, या अनैच्छिक हरकतें (एक्स्ट्रापाइरामिडल लक्षण), दिल की धड़कन में अनियमितता, और एलर्जी प्रतिक्रियाएँ शामिल हो सकती हैं। लंबे समय तक उपयोग से विटामिन बी12 की कमी और मैग्नीशियम की कमी हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कैप्सूल को चबाएं या तोड़ें नहीं, पूरा निगलें। इसे खाली पेट, भोजन से 30-60 मिनट पहले लें। शराब का सेवन न करें, क्योंकि इससे पेट की समस्या और लीवर पर असर बढ़ सकता है। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, वाहन चलाने या मशीनरी चलाने से बचें। अगर आपको किडनी, लीवर, या दिल की बीमारी है, तो डॉक्टर को बताएं। डॉक्टर की सलाह के बिना दवा बंद न करें।
💊 cforge l 75mg/40mg capsule Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"This medicine helps reduce acid reflux symptoms such as heartburn and regurgitation by suppressing gastric acid secretion and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"It relieves symptoms of functional dyspepsia including postprandial fullness, early satiety, and epigastric pain by enhancing gastrointestinal motility and reducing acid.","evidence":"Moderate"},{"condition":"Peptic ulcer disease","description":"Used as part of therapy to promote ulcer healing by reducing acid and improving gastric emptying, though it is not a first-line treatment for active ulcers.","evidence":"Limited"},{"condition":"Diabetic gastroparesis","description":"Levosulpiride component may help improve delayed gastric emptying in diabetic patients, while esomeprazole protects the stomach lining.","evidence":"Limited"}]
Off-label uses: [{"condition":"Nausea and vomiting","description":"Levosulpiride has antiemetic properties and may be used off-label for nausea, but this combination is not primarily indicated for this purpose.","evidence":"Limited"},{"condition":"Irritable bowel syndrome (IBS)","description":"Some clinicians may prescribe this combination for IBS with dyspepsia, but evidence is not robust.","evidence":"Insufficient"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Peptic ulcer disease, Diabetic gastroparesis
📋 Drug Information
| Generic Name(s) | Levosulpiride + Esomeprazole |
| Brand Name | Ageflux OLX Capsule SR |
| Manufacturer | Medocean Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Levosulpiride is a substituted benzamide that selectively blocks dopamine D2 receptors in the chemoreceptor trigger zone and gastrointestinal tract. This blockade enhances gastric motility, accelerates gastric emptying, and exerts antiemetic effects. Esomeprazole is a proton pump inhibitor that irreversibly inhibits the gastric H+/K+ ATPase enzyme in parietal cells, thereby suppressing both basal and stimulated gastric acid secretion. Together, they reduce acid exposure and improve upper gastrointestinal motility, addressing both acid-related and motility-related symptoms.
Mechanism Steps
💡 How to Take cforge l 75mg/40mg capsule
Strength: Sustained-release capsule containing Levosulpiride 75 mg and Esomeprazole 40 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule of this medicine (Levosulpiride 75 mg + Esomeprazole 40 mg) taken orally once daily on an empty stomach, at least 30 to 60 minutes before breakfast. However, the dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, and renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of levosulpiride, especially extrapyramidal symptoms. Use with caution and consider lower doses as prescribed by a clinician. |
| Renal Impairment | Levosulpiride is primarily excreted by the kidneys. In patients with renal impairment, dose reduction may be necessary. Consult a clinician for individualized dosing. |
| Hepatic Impairment | Esomeprazole is metabolized by the liver. In patients with severe hepatic impairment, the maximum dose of esomeprazole should not exceed 20 mg daily. Consult a clinician for dose adjustment. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (Levosulpiride 75 mg + Esomeprazole 40 mg) per day. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cforge l 75mg/40mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Clopidogrel | Major | |
| Methotrexate | Major | |
| Digoxin | Major | |
| Ketoconazole | Moderate | |
| Atazanavir | Moderate | |
| Diazepam | Moderate | |
| Phenytoin | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Warfarin
- Clopidogrel
- Methotrexate
- Digoxin
⚡ Moderate Interactions
- Ketoconazole, itraconazole
- Atazanavir, nelfinavir
- Diazepam
- Phenytoin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding, worsen acid reflux, and may enhance the sedative effects of levosulpiride, leading to increased drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to levosulpiride, esomeprazole, or any component of the formulation","Parkinson's disease","Epilepsy","Pheochromocytoma","Breast cancer","Severe renal impairment","Concomitant use with clopidogrel","Children and adolescents under 18 years"]
⚠️ Warnings & Precautions
["May cause drowsiness and dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol consumption while taking this medicine.","Use with caution in elderly patients due to increased risk of extrapyramidal symptoms.","Long-term use may lead to vitamin B12 deficiency and hypomagnesemia.","May increase the risk of bone fractures with prolonged use.","Not recommended during pregnancy or breastfeeding unless clearly needed.","Use with caution in patients with cardiovascular disease.","May mask symptoms of gastric malignancy; rule out malignancy before starting therapy."]
🤱 Lactation Safety
Not established from the available information. It is not known if levosulpiride or esomeprazole are excreted in human breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe extrapyramidal symptoms, drowsiness, and cardiac arrhythmias. There is no specific antidote. Treatment is symptomatic and supportive. If overdose is suspected, seek immediate medical attention. Contact a poison control center if available.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the sustained-release capsule; swallow it whole with water. It is best taken on an empty stomach, at least 30 to 60 minutes before a meal, to maximize the effect of esomeprazole. Avoid alcohol while taking this medicine, as it can worsen gastrointestinal side effects and increase the risk of liver problems. Do not drive or operate heavy machinery until you know how this medicine affects you, as it may cause drowsiness or dizziness. Inform your doctor if you have kidney or liver disease, heart problems, or a history of seizures. Do not stop taking this medicine abruptly without consulting your doctor, as rebound acid hypersecretion may occur. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of extrapyramidal symptoms, cardiac arrhythmias, and renal impairment. Use with caution and monitor closely. Dose adjustment may be necessary.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for alternative treatments if you are trying to conceive.
🏥 Post-Surgery Considerations
Use with caution after surgery, as levosulpiride may affect gastric motility and esomeprazole may interact with other medications. Consult your surgeon before resuming.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may increase the risk of bleeding during dental procedures. Your dentist may recommend temporary discontinuation or monitoring.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid vigorous exercise immediately after taking the medicine, as it may worsen reflux. Listen to your body and stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is best to take it before breakfast so that any sedative effect wears off during the day.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as extrapyramidal symptoms, cardiac arrhythmias, or severe allergic reactions, seek immediate medical attention and follow your doctor's advice on discontinuation.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to vitamin B12 deficiency, hypomagnesemia, and an increased risk of bone fractures due to esomeprazole. Levosulpiride may cause tardive dyskinesia with prolonged use. Regular monitoring of vitamin B12, magnesium, and renal function is advised. Periodic review with your doctor is necessary to assess the need for continued therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and elevating the head of the bed can help manage GERD symptoms.
Evidence: Well-establishedAlternative PPIs like pantoprazole or rabeprazole may be used if esomeprazole is not suitable.
Evidence: Well-establishedRanitidine or famotidine can reduce acid production but are less potent than PPIs.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, long-term use of esomeprazole may increase the risk of gastrointestinal infections. Ensure routine vaccinations are up to date.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking it at the same time relative to your new local schedule, but consult your doctor for specific advice. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts reducing acid within 1 hour, but noticeable relief from symptoms may take a few days. Full effects on motility may take 1-2 weeks.
A: It should be taken on an empty stomach, at least 30-60 minutes before a meal, to ensure proper absorption.
A: Common side effects include headache, nausea, diarrhea, abdominal pain, and dry mouth. These are usually mild and temporary.
A: It is not recommended during pregnancy unless clearly needed. Consult your doctor if you are pregnant or planning to become pregnant.
A: No, stopping suddenly can cause rebound acid hypersecretion. Always consult your doctor before stopping.
🤔 Common Patient Concerns
🔄 Substitutes for cforge l 75mg/40mg capsule
View AllAlternative brands with exact same active ingredient:
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davaindia levosulpiride+esomeprazole 75mg/40mg capsule srDavaindia Generic Pharmacy ₹50.00 66.7% CHEAPER
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stayhappi levosulpiride+esomeprazole 75mg/40mg capsuleSarvagunaushdhi Pvt Ltd ₹72.19 51.9% CHEAPER
-
esomez l 75mg/40mg capsule srAroma Healthcare ₹79.69 46.9% CHEAPER
-
gastro-sl capsuleSSK Pharma ₹103.13 31.2% CHEAPER
-
esjor-ls capsuleJaiwik Biotech ₹131.25 12.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken with food.
Fact: It should be taken on an empty stomach for best absorption. - Myth: It is safe to stop taking this medicine abruptly.
Fact: Stopping suddenly can cause rebound acid hypersecretion. Consult your doctor before stopping. - Myth: It can be used for immediate relief of heartburn.
Fact: It is not for immediate relief; it takes about an hour to start working.
🔄 Alternative Options
Generic Alternatives
- Levosulpiride + Esomeprazole generic capsules
Brand Alternatives
- Aegisco Remedies Pvt Ltd's Ageflux OLX Capsule SR