cexole 5mg/60mg tablet - Cetirizine (5mg) + Ambroxol (60mg) medicine

cexole 5mg/60mg tablet

4.4 (11 reviews)
๐Ÿญ Modgal Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is cexole 5mg/60mg tablet used for?

Amcold (Cetirizine + Ambroxol) is used to treat RESPIRATORY. It contains Cetirizine (5mg) + Ambroxol (60mg), which Cetirizine: Selective H1 receptor antagonist; Ambroxol: Increases airway secreti. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cetirizine + Ambroxol
  • Manufacturer: Modgal Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cexole 5mg/60mg tablet Uses & Benefits

Allergic rhinitis, cough with thick mucus, upper respiratory tract infections

Off-label uses: Chronic urticaria, COPD exacerbations

๐Ÿ“‹ Drug Information

Generic Name(s)Cetirizine + Ambroxol
Brand NameAmcold
ManufacturerModgal Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Mucolytic
Route of AdministrationOral
StorageStore at 25ยฐC (77ยฐF); protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionCetirizine: Well absorbed orally; Ambroxol: Rapidly absorbed from GI tract
DistributionCetirizine: Vd 0.5 L/kg; Ambroxol: Widely distributed, crosses placenta
Protein BindingCetirizine: 93%; Ambroxol: 90%
MetabolismCetirizine: Minimal hepatic metabolism; Ambroxol: Hepatic via glucuronidation
Half-LifeCetirizine: 8-11 hours; Ambroxol: 7-12 hours
ExcretionCetirizine: Renal (60% unchanged); Ambroxol: Renal (90% as metabolites)
BioavailabilityCetirizine: ~70%; Ambroxol: ~70-80%
Onset of ActionCetirizine: 1 hour; Ambroxol: 30 minutes
Peak Plasma TimeCetirizine: 1-2 hours; Ambroxol: 1-3 hours
Duration of ActionCetirizine: 24 hours; Ambroxol: 6-12 hours

How It Works

Cetirizine: Selective H1 receptor antagonist; Ambroxol: Increases airway secretion and reduces mucus viscosity

Mechanism Steps

1Cetirizine blocks H1 receptors, preventing histamine-mediated allergic responses
2Ambroxol stimulates serous bronchial glands, increasing fluid secretion
3Ambroxol depolymerizes mucopolysaccharides, reducing mucus viscosity

๐Ÿ’ก How to Take cexole 5mg/60mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cexole 5mg/60mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Fatigue
  • Nausea

๐Ÿšจ Serious Side Effects

  • Severe allergic reactions
  • Hepatotoxicity (rare)
  • Arrhythmias (rare)

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Stevens-Johnson syndrome
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
CNS depressants Major Enhanced sedation
Alcohol Major Increased CNS depression
MAOIs Major Risk of hypertensive crisis
Anticholinergics Moderate Additive anticholinergic effects
CYP3A4 inhibitors Moderate Increased ambroxol levels
Theophylline Minor Possible increased theophylline levels
Digoxin Minor Possible increased digoxin levels

๐Ÿšจ Major Interactions

  • CNS depressants
  • Alcohol
  • MAOIs

โšก Moderate Interactions

  • Anticholinergics
  • CYP3A4 inhibitors

โ„น๏ธ Minor Interactions

  • Theophylline
  • Digoxin

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption of cetirizine

๐Ÿท Alcohol Interaction

Increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe renal impairment (CrCl <10 mL/min)

๐Ÿ“Š Monitoring Parameters

Renal function, CNS effects, respiratory status

๐Ÿคฑ Lactation Safety

Cetirizine excreted in milk; Ambroxol likely safe

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage if recent

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

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