amcold 5 mg/60 mg tablet - Cetirizine (5mg) + Ambroxol (60mg) medicine

amcold 5 mg/60 mg tablet

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🏭 Cipla Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is amcold 5 mg/60 mg tablet used for?

This medicine contains Cetirizine (5mg) + Ambroxol (60mg) and is used to treat RESPIRATORY. Cetirizine: Selective H1 receptor antagonist; Ambroxol: Increases airway secretion and reduces mucus. Always consult your doctor before use.

  • Generic Name: Cetirizine + Ambroxol
  • Manufacturer: Cipla Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 amcold 5 mg/60 mg tablet Uses & Benefits

Allergic rhinitis, cough with thick mucus, upper respiratory tract infections

Off-label uses: Chronic urticaria, COPD exacerbations

📋 Drug Information

Generic Name(s)Cetirizine + Ambroxol
Brand NameAmcold
ManufacturerCipla Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Mucolytic
Route of AdministrationOral
StorageStore at 25°C (77°F); protect from light and moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCetirizine: Well absorbed orally; Ambroxol: Rapidly absorbed from GI tract
DistributionCetirizine: Vd 0.5 L/kg; Ambroxol: Widely distributed, crosses placenta
Protein BindingCetirizine: 93%; Ambroxol: 90%
MetabolismCetirizine: Minimal hepatic metabolism; Ambroxol: Hepatic via glucuronidation
Half-LifeCetirizine: 8-11 hours; Ambroxol: 7-12 hours
ExcretionCetirizine: Renal (60% unchanged); Ambroxol: Renal (90% as metabolites)
BioavailabilityCetirizine: ~70%; Ambroxol: ~70-80%
Onset of ActionCetirizine: 1 hour; Ambroxol: 30 minutes
Peak Plasma TimeCetirizine: 1-2 hours; Ambroxol: 1-3 hours
Duration of ActionCetirizine: 24 hours; Ambroxol: 6-12 hours

How It Works

Cetirizine: Selective H1 receptor antagonist; Ambroxol: Increases airway secretion and reduces mucus viscosity

Mechanism Steps

1Cetirizine blocks H1 receptors, preventing histamine-mediated allergic responses
2Ambroxol stimulates serous bronchial glands, increasing fluid secretion
3Ambroxol depolymerizes mucopolysaccharides, reducing mucus viscosity
4Combined effect: reduced allergy symptoms and easier expectoration

💡 How to Take amcold 5 mg/60 mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of amcold 5 mg/60 mg tablet

✅ Common Side Effects

Drowsiness
Dry mouth
Fatigue
Nausea

🚨 Serious Side Effects

Severe allergic reactions
Hepatotoxicity (rare)
Arrhythmias (rare)

⚠️ Rare Side Effects

Thrombocytopenia
Stevens-Johnson syndrome
Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
CNS depressants Major Enhanced sedation
Alcohol Major Increased CNS depression
MAOIs Major Risk of hypertensive crisis
Anticholinergics Moderate Additive anticholinergic effects
CYP3A4 inhibitors Moderate Increased ambroxol levels
Theophylline Minor Possible increased theophylline levels
Digoxin Minor Possible increased digoxin levels

🚨 Major Interactions

  • CNS depressants
  • Alcohol
  • MAOIs

⚡ Moderate Interactions

  • Anticholinergics
  • CYP3A4 inhibitors

🍷 Alcohol Interaction

Increased CNS depression

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to any component, severe renal impairment (CrCl

🤱 Lactation Safety

Cetirizine excreted in milk; Ambroxol likely safe

💊 Overdose Management

Symptomatic and supportive; gastric lavage if recent

⏰ Missed Dose

Take as soon as remembered; skip if almost time for next dose

🔄 Substitutes for amcold 5 mg/60 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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