celplanin 400mg injection - Teicoplanin (400mg) medicine

celplanin 400mg injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Celon Laboratories Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is celplanin 400mg injection used for?

Bacteplanin 400mg Injection (Teicoplanin) is used to treat ANTI INFECTIVES. It contains Teicoplanin (400mg), which Inhibits bacterial cell wall synthesis by binding to D-alanyl-D-alanine terminus. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Teicoplanin
  • Manufacturer: Celon Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š celplanin 400mg injection Uses & Benefits

Serious Gram-positive infections including MRSA, endocarditis, osteomyelitis, septic arthritis, and skin/soft tissue infections.

Off-label uses: Catheter-related infections, Prophylaxis in prosthetic joint surgery

๐Ÿ“‹ Drug Information

Generic Name(s)Teicoplanin
Brand NameBacteplanin 400mg Injection
ManufacturerCelon Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassGlycopeptides
Route of AdministrationIntravenous (IV) or Intramuscular (IM).
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntramuscular administration results in complete absorption; intravenous administration provides immediate bioavailability.
DistributionWidely distributed into tissues, including bone, skin, and lungs; penetrates poorly into cerebrospinal fluid.
Protein Binding90-95% bound to serum albumin.
MetabolismNot significantly metabolized; primarily excreted unchanged.
Half-Life70-100 hours (can extend up to 150 hours in renal impairment).
ExcretionPrimarily renal (80% unchanged in urine) via glomerular filtration.
Bioavailability90-100% (IM); 100% (IV).
Onset of ActionRapid (within 1 hour after IV administration).
Peak Plasma TimeIM: 4-6 hours; IV: immediately after infusion.
Duration of Action24 hours (once daily dosing).

How It Works

Inhibits bacterial cell wall synthesis by binding to D-alanyl-D-alanine terminus of peptidoglycan precursors, preventing transglycosylation and transpeptidation.

Mechanism Steps

1Binds to D-alanyl-D-alanine terminus of peptidoglycan precursors
2Prevents transglycosylation (polymerization of peptidoglycan)
3Prevents transpeptidation (cross-linking of peptidoglycan chains)

๐Ÿ’ก How to Take celplanin 400mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of celplanin 400mg injection

โœ… Common Side Effects

  • Injection site reactions
  • Rash
  • Fever
  • Nausea
  • Diarrhea

๐Ÿšจ Serious Side Effects

  • Nephrotoxicity
  • Ototoxicity
  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Clostridioides difficile colitis

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Leukopenia
  • Red man syndrome (rare with teicoplanin)
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aminoglycosides Major Increased nephrotoxicity and ototoxicity
Cyclosporine Major Increased nephrotoxicity
Amphotericin B Major Increased nephrotoxicity
Cisplatin Major Increased nephrotoxicity
Loop diuretics Moderate Increased ototoxicity
ACE inhibitors Moderate Increased risk of hyperkalemia
NSAIDs Moderate Increased nephrotoxicity
Vancomycin Moderate Additive nephrotoxicity
Oral contraceptives Minor Possible reduced efficacy
Antacids Minor Reduced absorption (oral)

๐Ÿšจ Major Interactions

  • Warfarin
  • Aminoglycosides
  • Cyclosporine
  • Amphotericin B
  • Cisplatin

โšก Moderate Interactions

  • Loop diuretics
  • ACE inhibitors
  • NSAIDs
  • Vancomycin

โ„น๏ธ Minor Interactions

  • Oral contraceptives
  • Antacids

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to teicoplanin or vancomycin.

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, CBC, serum drug levels (trough), signs of ototoxicity.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; use with caution.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may remove small amounts.

โฐ Missed Dose

Administer as soon as remembered; if near next dose, skip missed dose and resume regular schedule.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for celplanin 400mg injection

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Alternative brands with exact same active ingredient (Teicoplanin (400mg)):

Medical Note: Always consult your doctor before switching medications.

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