celomide 25 capsule - Lenalidomide (25mg) medicine

celomide 25 capsule - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Celon Laboratories Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is celomide 25 capsule used for?

Celomide (Lenalidomide) is used to treat ANTI INFECTIVES. It contains Lenalidomide (25mg), which Immunomodulatory agent with anti-angiogenic, anti-proliferative, and pro-apoptot. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Lenalidomide
  • Manufacturer: Celon Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š celomide 25 capsule Uses & Benefits

Multiple myeloma, myelodysplastic syndromes, lepra reaction.

Off-label uses: Chronic lymphocytic leukemia, non-Hodgkin lymphoma, amyloidosis.

๐Ÿ“‹ Drug Information

Generic Name(s)Lenalidomide
Brand NameCelomide
ManufacturerCelon Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassThalidomide & its Immunomodulatory derivatives (IMiDs)
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; food does not affect absorption.
DistributionWidely distributed; crosses placenta; present in semen.
Protein BindingApproximately 30% bound to plasma proteins.
MetabolismMetabolized primarily via hydrolysis; minor CYP-mediated metabolism.
Half-LifeApproximately 3 hours in healthy subjects; prolonged in renal impairment.
ExcretionPrimarily excreted unchanged in urine (approximately 67%).
BioavailabilityNot fully established; oral bioavailability is high.
Onset of ActionNot well defined; therapeutic effects may take weeks to months.
Peak Plasma Time0.5 to 2 hours after oral administration.
Duration of ActionNot well defined; dosing is continuous.

How It Works

Immunomodulatory agent with anti-angiogenic, anti-proliferative, and pro-apoptotic properties.

Mechanism Steps

1Lenalidomide binds to cereblon (CRBN) within the E3 ubiquitin ligase complex.
2This binding alters substrate specificity of the complex.
3Leads to ubiquitination and degradation of transcription factors Ikaros (IKZF1) and Aiolos (IKZF3).

๐Ÿ’ก How to Take celomide 25 capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of celomide 25 capsule

โœ… Common Side Effects

  • Headache
  • Weakness
  • Nausea
  • Rash
  • Dizziness
  • Diarrhea
  • Constipation
  • Fatigue

๐Ÿšจ Serious Side Effects

  • Neutropenia
  • Thrombocytopenia
  • Deep vein thrombosis
  • Pulmonary embolism
  • Severe skin reactions
  • Hepatotoxicity

โš ๏ธ Rare Side Effects

  • Tumor lysis syndrome
  • Progressive multifocal leukoencephalopathy
  • Peripheral neuropathy
  • Hypothyroidism

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Digoxin Major Increased digoxin levels
Corticosteroids Major Increased risk of thromboembolism
Other immunosuppressants Major Additive immunosuppression
CYP3A4 inhibitors Moderate Increased lenalidomide levels
CYP3A4 inducers Moderate Decreased lenalidomide levels
NSAIDs Moderate Increased risk of bleeding
Hormonal contraceptives Moderate Reduced contraceptive efficacy
Antacids Minor Possible decreased absorption
Grapefruit juice Minor Possible minor interaction

๐Ÿšจ Major Interactions

  • Warfarin
  • Digoxin
  • Corticosteroids
  • Other immunosuppressants

โšก Moderate Interactions

  • CYP3A4 inhibitors
  • CYP3A4 inducers
  • NSAIDs
  • Hormonal contraceptives

โ„น๏ธ Minor Interactions

  • Antacids
  • Grapefruit juice

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; can be taken with or without food.

๐Ÿท Alcohol Interaction

Avoid alcohol due to increased risk of hepatotoxicity and dizziness.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Pregnancy, breastfeeding, hypersensitivity to lenalidomide, women of childbearing potential not using effective contraception.

๐Ÿ“Š Monitoring Parameters

Complete blood count (CBC) regularly; liver and renal function tests; pregnancy test for women of childbearing potential.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in milk in animal studies.

๐Ÿ’Š Overdose Management

No specific antidote; supportive care; monitor blood counts and electrolytes.

โฐ Missed Dose

If missed, take as soon as remembered unless next dose is within 12 hours; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for celomide 25 capsule

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Alternative brands with exact same active ingredient (Lenalidomide (25mg)):

Medical Note: Always consult your doctor before switching medications.

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