Celicx 200 Capsule - Celecoxib (200mg) medicine

Celebrex 200mg Capsule: Complete Medicine Guide

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🏭 Goldenlad Pharmaceutical Pvt Ltd 📦 strip of 10 capsules 💊 Allopathy 📅 Updated: Oct 28, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category This medicine is not recommended during pregnancy, especially in the third trimester, as it may cause premature closure of the ductus arteriosus and other complications. Use only if clearly needed and prescribed by a doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: High for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 28, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual weight gain or swelling in ankles
  • Severe rash or blistering of skin

If experiencing severe symptoms, call emergency services immediately.

What is Celicx 200 Capsule used for?

This medicine is a selective COX-2 inhibitor NSAID used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and acute pain. It works by blocking the COX-2 enzyme, reducing prostaglandins that cause pain and swelling. It is taken orally with food, usually 100-200 mg once or twice daily, and requires a prescription.

  • Generic Name: Celecoxib (200mg)
  • Manufacturer: Goldenlad Pharmaceutical Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Celicx 200 Capsule के बारे में (Hindi Summary)

उपयोग: यह दवा मुख्य रूप से गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), रीढ़ की हड्डी की सूजन (एंकिलोज़िंग स्पॉन्डिलाइटिस), और तीव्र दर्द जैसे मांसपेशियों की चोट या सर्जरी के बाद के दर्द के इलाज के लिए इस्तेमाल की जाती है। यह दर्द, सूजन और जकड़न को कम करने में मदद करती है। यह दवा कोक्स-2 एंजाइम को रोककर काम करती है, जिससे सूजन पैदा करने वाले प्रोस्टाग्लैंडिन कम होते हैं। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और इसे डॉक्टर की सलाह के अनुसार ही लेना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में अपच, पेट दर्द, मतली, दस्त, सिरदर्द, चक्कर आना और त्वचा पर हल्के दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें दिल का दौरा, स्ट्रोक, पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, लीवर की समस्या और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको सीने में दर्द, सांस लेने में कठिनाई, काला मल, खून की उल्टी, गंभीर पेट दर्द, पेशाब कम आना, आंखों या त्वचा का पीलापन, या चेहरे, होंठ या गले में सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। पेट की जलन से बचने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब न पिएं क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आपको दिल की बीमारी, उच्च रक्तचाप, गुर्दे या लीवर की समस्या, या पेट के अल्सर की history है, तो अपने डॉक्टर को बताएं। अन्य NSAIDs (जैसे इबुप्रोफेन, नेप्रोक्सन, या एस्पिरिन) को बिना डॉक्टर की सलाह के साथ न लें। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो इस दवा का उपयोग करने से पहले अपने डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 Celicx 200 Capsule Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in adults with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate pain and inflammation in the spine and sacroiliac joints.","evidence":"Well-established"},{"condition":"Acute pain","description":"Used for short-term management of acute musculoskeletal pain, post-operative pain, and dysmenorrhea.","evidence":"Well-established"},{"condition":"Familial adenomatous polyposis (FAP)","description":"Adjunct to usual care to reduce the number of colorectal polyps in adults with FAP.","evidence":"Established for specific indication"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Cancer pain","description":"May be used as part of multimodal analgesia in cancer pain, but not first-line.","evidence":"Limited"}]

Primary treatment for: Osteoarthritis

Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute pain, Familial adenomatous polyposis

📋 Drug Information

Generic Name(s)Celecoxib (200mg)
Brand NameCelicx 200 Capsule
ManufacturerGoldenlad Pharmaceutical Pvt Ltd
Packaging / Formstrip of 10 capsules (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature between 20°C and 25°C (68°F to 77°F). Keep away from moisture and heat. Keep in the original container, tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Use the lowest effective dose for the shortest duration possible.
3
Avoid alcohol while taking this medicine to prevent gastrointestinal bleeding.
4
Do not take other NSAIDs concurrently unless specifically instructed.
5
Monitor blood pressure regularly, especially if you have hypertension.
6
Report any signs of gastrointestinal bleeding, such as black stools or vomiting blood, immediately.
7
If you have heart disease or risk factors, discuss the risks and benefits with your doctor.
8
Stay well hydrated to support kidney function.
9
Do not stop this medicine abruptly without consulting your doctor if you have been on long-term therapy.
10
Keep all follow-up appointments for monitoring kidney and liver function.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Acute muscle pain
This medicine can be used for short-term relief.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed after oral administration, with peak plasma concentrations occurring approximately 2 to 3 hours after ingestion. Food, especially a high-fat meal, can delay absorption and increase peak concentration.
DistributionThis medicine is highly protein-bound and distributes widely into tissues. It has a volume of distribution of approximately 400 L in healthy adults.
Protein BindingApproximately 97% bound to plasma proteins, primarily albumin.
MetabolismThis medicine is extensively metabolized in the liver, primarily by cytochrome P450 2C9 (CYP2C9), with minor contributions from CYP3A4. The main metabolites are inactive.
Half-LifeThe elimination half-life is approximately 11 hours.
ExcretionThis medicine is excreted mainly in the feces (about 57%) and urine (about 27%) as metabolites. Less than 1% is excreted unchanged in urine.
BioavailabilityThe absolute bioavailability of this medicine is not established from the available information, but it is well absorbed orally.
Onset of ActionPain relief typically begins within 30 to 60 minutes after oral administration, but full anti-inflammatory effects may take several days to weeks.
Peak Plasma TimePeak plasma concentration occurs approximately 2 to 3 hours after oral administration.
Duration of ActionThe duration of analgesic effect is approximately 8 to 12 hours, but anti-inflammatory effects persist with regular dosing.

How It Works

This medicine selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, which is induced by inflammatory stimuli and responsible for producing prostaglandins that cause pain, inflammation, and fever. By blocking COX-2, it reduces these symptoms with less impact on COX-1, which is constitutively expressed in the stomach and platelets. This selectivity decreases, but does not eliminate, the risk of gastrointestinal ulceration and bleeding compared to non-selective NSAIDs.

Mechanism Steps

1
Selective COX-2 binding: This medicine binds selectively to the COX-2 enzyme, which is upregulated during inflammation.
2
Inhibition of prostaglandin synthesis: By inhibiting COX-2, it blocks the conversion of arachidonic acid to prostaglandin H2, reducing downstream pain and inflammation mediators.
3
Reduced pain and inflammation: The decrease in prostaglandins leads to less pain, swelling, and joint stiffness.
4
Minimal COX-1 effect: Because it spares COX-1, there is less gastric irritation and platelet inhibition compared to non-selective NSAIDs.

💡 How to Take Celicx 200 Capsule

Strength: 200 mg immediate-release capsule

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a full glass of water.
3Take with food or milk to reduce stomach upset.
4Do not crush, chew, or open the capsule.
5Take at the same time each day to maintain consistent levels.
6If you miss a dose, follow the missed dose instructions.
7Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose for osteoarthritis is 200 mg once daily or 100 mg twice daily. For rheumatoid arthritis, the usual dose is 100 mg to 200 mg twice daily. For ankylosing spondylitis, the usual dose is 200 mg once daily or 100 mg twice daily. For acute pain, the initial dose is 400 mg, followed by 200 mg if needed on the first day, then 200 mg twice daily as needed. For familial adenomatous polyposis, the usual dose is 400 mg twice daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be at increased risk of cardiovascular, gastrointestinal, and kidney adverse effects. Use the lowest effective dose for the shortest duration. No specific dose adjustment is recommended based on age alone, but individualization is necessary.
Renal ImpairmentFor patients with mild to moderate kidney impairment, no dose adjustment is needed. For severe kidney impairment (creatinine clearance <30 mL/min), use is not recommended. Consult a doctor for individualized dosing.
Hepatic ImpairmentFor patients with mild liver impairment (Child-Pugh Class A), no dose adjustment is needed. For moderate liver impairment (Child-Pugh Class B), reduce the dose by 50%. For severe liver impairment (Child-Pugh Class C), use is not recommended. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 400 mg for most indications, except for familial adenomatous polyposis where the dose is 400 mg twice daily (800 mg total daily). Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Celicx 200 Capsule

✅ Common Side Effects

Indigestion (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Nausea (Common (5-10%))
Take with food. Stay hydrated. Consult doctor if vomiting occurs.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if diarrhea is severe or lasts more than a few days.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black stool, vomiting blood, or severe abdominal pain.
Heart attack or stroke (Rare (<0.1%))
Call emergency services if you experience chest pain, shortness of breath, weakness on one side, or difficulty speaking.
Kidney injury (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Liver toxicity (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek immediate medical attention if you develop a rash with blisters, peeling skin, or sores in mouth.
Aseptic meningitis
Report severe headache, stiff neck, fever, and sensitivity to light to your doctor immediately.
Pancreatitis
Seek medical attention if you experience severe upper abdominal pain radiating to back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
ACE inhibitors Major
Diuretics Major
Lithium Major
Fluconazole Major
Corticosteroids Moderate
SSRIs Moderate
Aspirin Moderate
Antacids Minor
Omeprazole Minor

🚨 Major Interactions

  • Warfarin
  • ACE inhibitors and ARBs
  • Diuretics
  • Lithium
  • Fluconazole

⚡ Moderate Interactions

  • Corticosteroids
  • SSRIs
  • Aspirin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and can worsen stomach irritation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to celecoxib or sulfonamides","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Severe heart failure","Recent coronary artery bypass graft (CABG) surgery","Active gastrointestinal bleeding or peptic ulcer","Severe kidney disease","Severe liver disease","Pregnancy (third trimester)"]

⚠️ Warnings & Precautions

["This medicine may increase the risk of serious cardiovascular events. Use with caution in patients with cardiovascular risk factors.","This medicine can cause gastrointestinal bleeding, ulceration, and perforation, which can be fatal. Use with caution in patients with a history of peptic ulcer disease or GI bleeding.","This medicine can cause kidney injury. Use with caution in patients with kidney disease, heart failure, or dehydration.","This medicine can cause liver injury. Monitor liver function in patients with liver disease.","This medicine may cause fluid retention and edema. Use with caution in patients with heart failure or hypertension.","This medicine may cause severe skin reactions. Discontinue at the first sign of rash or other allergic reaction.","This medicine should not be used in patients with known sulfonamide allergy.","This medicine may mask signs of infection, such as fever.","This medicine should be used with caution in the elderly, who are at higher risk of adverse effects.","This medicine should not be used during pregnancy unless clearly needed."]

🤱 Lactation Safety

This medicine is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, stomach pain, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, and cardiovascular events. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be considered if the overdose is recent. Hemodialysis is not effective in removing celecoxib.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while on this medicine as it increases the risk of gastrointestinal bleeding. Inform your doctor if you have a history of heart disease, high blood pressure, kidney or liver problems, or stomach ulcers. Do not take other NSAIDs (like ibuprofen, naproxen, or aspirin) concurrently unless specifically instructed. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Store at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients (above 65 years) are at higher risk of cardiovascular, gastrointestinal, and kidney side effects. Use the lowest effective dose for the shortest duration. Regular monitoring of kidney and liver function, blood pressure, and signs of bleeding is recommended.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy, especially in the third trimester, as it may cause premature closure of the ductus arteriosus. If you are planning pregnancy, consult your doctor to discuss alternative treatments. Use effective contraception while on this medicine.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain, but it is contraindicated after coronary artery bypass graft (CABG) surgery. Consult your surgeon before using this medicine after any surgery. It may increase the risk of bleeding and kidney problems.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may increase the risk of bleeding. Your dentist may recommend stopping it temporarily or taking precautions.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture and ergonomics.
💧
Include anti-inflammatory foods in your diet, such as fruits, vegetables, and omega-3 rich fish.
🧘
Get adequate sleep to help your body recover.
🌞
Manage stress through relaxation techniques like yoga or meditation.

🏋️ Exercise Considerations

While taking this medicine, you may experience dizziness or fatigue. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. Low-impact exercises are generally safe and beneficial for joint health.

🥗 Diet Recommendations

Include omega-3 rich foods like salmon, flaxseeds, and walnuts.
Reduce processed food and sugar intake.
Stay well hydrated by drinking plenty of water.
Eat a balanced diet rich in fruits and vegetables.
Limit alcohol consumption.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not significantly impact your ability to work if you follow your doctor's instructions and manage side effects.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, especially if you have been on long-term therapy. Your doctor may taper the dose or switch you to another medicine. If you experience serious side effects, seek immediate medical attention and follow your doctor's advice.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of serious cardiovascular events, gastrointestinal bleeding, kidney injury, and liver toxicity. Regular monitoring of blood pressure, kidney function, and liver function is recommended. Use the lowest effective dose for the shortest duration possible. Discuss with your doctor if you need to use this medicine for more than a few weeks.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve joint function.

Evidence: Well-established
Acupuncture

May help with pain relief in some patients.

Evidence: Moderate
Weight loss

Reduces stress on weight-bearing joints and improves osteoarthritis symptoms.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the immune response to vaccines. Consult your doctor about the timing of vaccinations while on this medicine. It is not known to interact with most vaccines, but live vaccines should be avoided if you are on immunosuppressive therapy.

📦 Storage Guide

✅ DO

Store at room temperature (20-25°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue your regular dosing schedule as closely as possible. Check local customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old woman with rheumatoid arthritis
Was prescribed this medicine along with methotrexate. She experienced good pain relief but developed mild indigestion. Her doctor advised taking it with meals and added a proton pump inhibitor. She continued treatment with regular monitoring.
💡 Lesson: Combining this medicine with other arthritis treatments can be effective, but monitoring for side effects and using gastroprotection when needed is important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts relieving pain within 30 to 60 minutes, but full anti-inflammatory effects may take several days to weeks of regular use.

Q: Can I take this medicine with food?

A: Yes, taking it with food or milk is recommended to reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe for long-term use?

A: Long-term use may increase the risk of cardiovascular and gastrointestinal side effects. It should be used at the lowest effective dose for the shortest duration, with regular monitoring by your doctor.

Q: Can I drink alcohol while taking this medicine?

A: It is best to avoid alcohol as it can increase the risk of stomach bleeding and irritation.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Celicx 200 Capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is completely safe for the stomach.
    Fact: While it has a lower risk of stomach ulcers than non-selective NSAIDs, it can still cause gastrointestinal bleeding and ulceration.
  • Myth: This medicine can be taken without a prescription.
    Fact: This medicine is a prescription-only medicine and should only be taken under medical supervision.
  • Myth: This medicine is safe to take during pregnancy.
    Fact: This medicine is not recommended during pregnancy, especially in the third trimester, as it may harm the fetus.

🔄 Alternative Options

Generic Alternatives

  • Celecoxib

Brand Alternatives

  • Celebrex
  • Cobix
  • Zycel

📊 Comparison with Similar Medicines

[{"medicine":"Celecoxib","class":"COX-2 selective","gi_risk":"Lower","cardiovascular_risk":"Increased","dosing_frequency":"Once or twice daily"},{"medicine":"Diclofenac","class":"Non-selective","gi_risk":"Higher","cardiovascular_risk":"Increased","dosing_frequency":"Two to three times daily"},{"medicine":"Naproxen","class":"Non-selective","gi_risk":"Higher","cardiovascular_risk":"Lower","dosing_frequency":"Twice daily"}]

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