dexsofighter 60 capsule mr - Dexlansoprazole (60mg) medicine

Dexlansoprazole 60 Mg Delayed-release Capsules: Complete Guide

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🏭 Goldenlad Pharmaceutical Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 28, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Oct 28, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or black, tarry stools
  • Severe abdominal pain
  • Difficulty breathing or swelling of face, lips, or throat
  • Decreased urine output or swelling in legs
  • Severe diarrhea that does not improve
  • Yellowing of skin or eyes
  • Irregular heartbeat or muscle cramps

If experiencing severe symptoms, call emergency services immediately.

What is dexsofighter 60 capsule mr used for?

Dexlansoprazole 60 mg is a proton pump inhibitor used to treat gastroesophageal reflux disease (GERD) and erosive esophagitis. It works by reducing stomach acid production. The usual adult dose is 60 mg once daily, swallowed whole. It is generally well-tolerated but may cause diarrhea, headache, or nausea.

  • Generic Name: Dexlansoprazole (60mg)
  • Manufacturer: Goldenlad Pharmaceutical Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dexsofighter 60 capsule mr के बारे में (Hindi Summary)

उपयोग: यह दवा डेक्सलैंसोप्राजोल 60 मिलीग्राम का डिलेड-रिलीज़ कैप्सूल है, जिसका उपयोग गैस्ट्रोएसोफेजियल रिफ्लक्स डिजीज (GERD) और इरोसिव एसोफेजाइटिस के इलाज के लिए किया जाता है। यह पेट में एसिड के उत्पादन को कम करती है और सीने में जलन, एसिड रिगर्जिटेशन और निगलने में कठिनाई जैसे लक्षणों से राहत देती है। यह दवा आमतौर पर वयस्कों के लिए निर्धारित की जाती है और इसे डॉक्टर के निर्देशानुसार ही लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, सिरदर्द, मतली, पेट दर्द, गैस और ऊपरी श्वसन संक्रमण शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, किडनी की समस्या और क्लोस्ट्रीडियम डिफिसाइल से जुड़े दस्त हो सकते हैं। लंबे समय तक उपयोग से मैग्नीशियम और विटामिन बी12 की कमी हो सकती है। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कैप्सूल को पूरा निगलें, चबाएं या तोड़ें नहीं। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है। शराब से बचें क्योंकि इससे पेट में जलन बढ़ सकती है। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको किडनी या लीवर की बीमारी है, तो डॉक्टर को बताएं। दवा को कमरे के तापमान पर सूखी जगह पर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 dexsofighter 60 capsule mr Uses & Benefits

[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Provides relief from heartburn and acid regurgitation by reducing gastric acid secretion.","evidence":"Well-established"},{"condition":"Erosive esophagitis","description":"Heals erosions in the esophagus and maintains healing.","evidence":"Well-established"},{"condition":"Maintenance of healed erosive esophagitis","description":"Prevents relapse of erosive esophagitis.","evidence":"Well-established"},{"condition":"Non-erosive reflux disease (NERD)","description":"May be used to manage symptoms of NERD.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Barrett's esophagus","description":"Sometimes prescribed to reduce acid exposure in Barrett's esophagus.","evidence":"Limited"},{"condition":"Zollinger-Ellison syndrome","description":"May be used to reduce gastric acid hypersecretion.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease (GERD)

Also treats: Erosive esophagitis, Non-erosive reflux disease, Barrett's esophagus

📋 Drug Information

Generic Name(s)Dexlansoprazole (60mg)
Brand Namedexsofighter 60 capsule mr
ManufacturerGoldenlad Pharmaceutical Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProton pump inhibitors
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep the container tightly closed and protect from moisture and light.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day for best results.
2
Swallow the capsule whole; do not crush or chew it.
3
If you have trouble swallowing, consult your doctor for alternative formulations.
4
Long-term use may require periodic monitoring of magnesium and vitamin B12 levels.
5
Report any severe diarrhea, rash, or muscle cramps to your doctor immediately.
6
Avoid alcohol and spicy foods to reduce stomach irritation.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Heartburn
This medicine is commonly prescribed for this.
Likely Use
✅
Acid regurgitation
This medicine reduces acid production.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDexlansoprazole is well absorbed after oral administration. The dual delayed-release formulation results in two distinct plasma concentration peaks. Food does not significantly affect the extent of absorption.
DistributionIt is highly protein-bound and distributes into tissues, including the gastric parietal cells.
Protein BindingApproximately 96-99% bound to plasma proteins.
MetabolismDexlansoprazole is extensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP2C19 and CYP3A4.
Half-LifeThe elimination half-life is approximately 1-2 hours.
ExcretionIt is excreted mainly as metabolites in urine and feces.
BioavailabilityThe absolute bioavailability is approximately 50-60%.
Onset of ActionAcid suppression begins within 1 hour of administration.
Peak Plasma TimePeak plasma concentrations occur at approximately 1-2 hours and 4-5 hours post-dose due to the dual release.
Duration of ActionAcid suppression lasts for approximately 24 hours.

How It Works

Dexlansoprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase enzyme system at the secretory surface of gastric parietal cells. It blocks the final step of acid production, thereby reducing both basal and stimulated acid secretion.

Mechanism Steps

1
Accumulation in acidic environment: Dexlansoprazole accumulates in the acidic canaliculi of gastric parietal cells.
2
Activation: It is converted to its active form, a sulfenamide, in the acidic environment.
3
Binding to proton pump: The active form binds covalently to cysteine residues on the H+/K+-ATPase enzyme.
4
Inhibition of acid secretion: This binding irreversibly inhibits the proton pump, blocking the final step of acid secretion.

💡 How to Take dexsofighter 60 capsule mr

Strength: Dexlansoprazole 60 mg delayed-release capsules.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a glass of water.
3Do not chew, crush, or open the capsule.
4Can be taken with or without food.
5Take at the same time each day for best results.

Dosage Information

Adult DosageThe recommended adult dose is 60 mg once daily for erosive esophagitis and maintenance of healed erosive esophagitis. For non-erosive reflux disease, the dose is 30 mg once daily. The capsule should be swallowed whole; do not chew or crush. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo dosage adjustment is required based on age alone. However, elderly patients may be more sensitive to side effects. Use with caution and monitor renal and hepatic function.
Renal ImpairmentNo dosage adjustment is required for mild to moderate renal impairment. Not studied in severe renal impairment.
Hepatic ImpairmentFor patients with mild hepatic impairment (Child-Pugh A), no dosage adjustment is needed. For moderate hepatic impairment (Child-Pugh B), the maximum daily dose is 30 mg. Not recommended in severe hepatic impairment (Child-Pugh C).
Maximum Daily Dose60 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.
Alcohol
Avoid
May increase stomach irritation.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of dexsofighter 60 capsule mr

✅ Common Side Effects

Diarrhea (Common (≥2%))
Stay hydrated. Consult doctor if persistent.
Headache (Common (≥2%))
Usually resolves. Consult doctor if severe.
Nausea (Common (≥2%))
Take with food. Consult doctor if persistent.
Abdominal pain (Common (≥2%))
Monitor. Consult doctor if severe.
Flatulence (Common (≥2%))
Usually harmless. Consult doctor if bothersome.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
Contact doctor if severe diarrhea occurs.
Acute interstitial nephritis (Rare (<0.1%))
Seek medical attention if decreased urine output or swelling.
Hypomagnesemia (Uncommon (0.1-1%))
Report muscle cramps, seizures, or arrhythmias.
Bone fractures (Uncommon (0.1-1%))
Long-term use may increase risk. Discuss with doctor.

⚠️ Rare Side Effects

Cutaneous lupus erythematosus
Report rash or joint pain.
Fundic gland polyps
Usually benign. Monitor with endoscopy.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Rilpivirine Major
Atazanavir Major
Nelfinavir Major
Warfarin Moderate
Methotrexate Moderate
Digoxin Moderate
Antacids Minor
Sucralfate Minor

🚨 Major Interactions

  • Rilpivirine
  • Atazanavir
  • Nelfinavir

⚡ Moderate Interactions

  • Warfarin
  • Methotrexate
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase stomach irritation and worsen GERD symptoms. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to dexlansoprazole or any component of the formulation","Concomitant use with rilpivirine-containing products"]

⚠️ Warnings & Precautions

["May increase risk of Clostridium difficile-associated diarrhea.","Long-term use may cause hypomagnesemia.","May increase risk of bone fractures.","May cause cutaneous lupus erythematosus.","May interfere with vitamin B12 absorption.","Not recommended for children under 12 years.","Use with caution in patients with liver disease."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before breastfeeding.

💊 Overdose Management

There is no specific antidote. Symptomatic and supportive care should be provided. Dexlansoprazole is not removed by hemodialysis. Contact a poison control center or emergency room immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Swallow the capsule whole; do not chew, crush, or open it. It can be taken with or without food. Do not take more than the recommended dose. Avoid alcohol as it may worsen stomach irritation. Inform your doctor if you have kidney or liver disease, or if you are pregnant or breastfeeding. Do not use this medicine for more than 8 weeks without medical advice. Store at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects like hypomagnesemia and bone fractures. Use with caution and monitor renal and hepatic function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor. This medicine should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

Consult your doctor before resuming this medicine after surgery, especially if you have difficulty swallowing.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may increase the risk of bleeding during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce acid reflux.
🥗
Avoid lying down for at least 2 hours after meals.
😴
Elevate the head of your bed while sleeping.
💧
Eat smaller, more frequent meals.
🧘
Avoid trigger foods like spicy, fatty, or acidic foods.
🌞
Quit smoking and limit alcohol.

🏋️ Exercise Considerations

Moderate exercise is generally safe. Avoid vigorous exercise immediately after meals as it may worsen reflux. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include high-fiber foods
Avoid spicy and fatty foods
Limit caffeine and carbonated drinks
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It generally does not interfere with daily activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Long-term use should be reassessed periodically.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to vitamin B12 deficiency, low magnesium levels, increased risk of bone fractures, and Clostridium difficile infection. Regular monitoring of magnesium, vitamin B12, and bone density is advised. Review the need for continued therapy periodically.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet changes, weight loss, and elevating the head of the bed can reduce reflux symptoms.

Evidence: Well-established
H2 receptor blockers

Alternative acid-suppressing medicines like ranitidine or famotidine.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before any vaccination if you are on long-term therapy.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule gradually. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old man with chronic heartburn
He was prescribed this medicine for GERD. After taking it daily for a week, his heartburn episodes reduced significantly. He learned to take it at the same time each morning and avoid late-night meals.
💡 Lesson: Consistent daily use and lifestyle changes improve outcomes.
👤 A 35-year-old woman with erosive esophagitis
She experienced difficulty swallowing and chest pain. After 8 weeks of treatment with this medicine, her symptoms resolved and follow-up endoscopy showed healed esophagus.
💡 Lesson: Complete the full course as prescribed and attend follow-up appointments.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts reducing acid within 1 hour, but full symptom relief may take 1-4 days.

Q: Can I take it with other medicines?

A: Inform your doctor about all medicines you take, especially rilpivirine, warfarin, or methotrexate.

Q: Is it safe during pregnancy?

A: Consult your doctor. Use only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for dexsofighter 60 capsule mr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Dexlansoprazole can be taken indefinitely without any risk.
    Fact: Long-term use may lead to vitamin B12 deficiency, low magnesium, and increased fracture risk. Regular monitoring is advised.
  • Myth: Dexlansoprazole provides instant relief from heartburn.
    Fact: It may take 1-4 days to achieve full effect. It is not for immediate symptom relief.

🔄 Alternative Options

Generic Alternatives

  • Dexlansoprazole delayed-release capsules

Brand Alternatives

  • Dexilant
  • Dexilant SoluTab

📊 Comparison with Similar Medicines

[{"medicine":"Dexlansoprazole","class":"PPI","half_life":"1-2 hours","onset":"1 hour","duration":"24 hours"},{"medicine":"Omeprazole","class":"PPI","half_life":"0.5-1 hour","onset":"1 hour","duration":"24 hours"},{"medicine":"Esomeprazole","class":"PPI","half_life":"1-1.5 hours","onset":"1 hour","duration":"24 hours"}]

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