Celebrex 200mg Capsule: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual weight gain or swelling in ankles
- Severe rash or blistering of skin
If experiencing severe symptoms, call emergency services immediately.
What is Celcox 200mg Capsule used for?
This medicine is a selective COX-2 inhibitor NSAID used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and acute pain. It works by blocking the COX-2 enzyme, reducing prostaglandins that cause pain and swelling. It is taken orally with food, usually 100-200 mg once or twice daily, and requires a prescription.
- Generic Name: Celecoxib (200mg)
- Manufacturer: Lupin Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Celcox 200mg Capsule के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), रीढ़ की हड्डी की सूजन (एंकिलोज़िंग स्पॉन्डिलाइटिस), और तीव्र दर्द जैसे मांसपेशियों की चोट या सर्जरी के बाद के दर्द के इलाज के लिए इस्तेमाल की जाती है। यह दर्द, सूजन और जकड़न को कम करने में मदद करती है। यह दवा कोक्स-2 एंजाइम को रोककर काम करती है, जिससे सूजन पैदा करने वाले प्रोस्टाग्लैंडिन कम होते हैं। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और इसे डॉक्टर की सलाह के अनुसार ही लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में अपच, पेट दर्द, मतली, दस्त, सिरदर्द, चक्कर आना और त्वचा पर हल्के दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें दिल का दौरा, स्ट्रोक, पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, लीवर की समस्या और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको सीने में दर्द, सांस लेने में कठिनाई, काला मल, खून की उल्टी, गंभीर पेट दर्द, पेशाब कम आना, आंखों या त्वचा का पीलापन, या चेहरे, होंठ या गले में सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। पेट की जलन से बचने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब न पिएं क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आपको दिल की बीमारी, उच्च रक्तचाप, गुर्दे या लीवर की समस्या, या पेट के अल्सर की history है, तो अपने डॉक्टर को बताएं। अन्य NSAIDs (जैसे इबुप्रोफेन, नेप्रोक्सन, या एस्पिरिन) को बिना डॉक्टर की सलाह के साथ न लें। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो इस दवा का उपयोग करने से पहले अपने डॉक्टर से सलाह लें।
💊 Celcox 200mg Capsule Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in adults with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate pain and inflammation in the spine and sacroiliac joints.","evidence":"Well-established"},{"condition":"Acute pain","description":"Used for short-term management of acute musculoskeletal pain, post-operative pain, and dysmenorrhea.","evidence":"Well-established"},{"condition":"Familial adenomatous polyposis (FAP)","description":"Adjunct to usual care to reduce the number of colorectal polyps in adults with FAP.","evidence":"Established for specific indication"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Cancer pain","description":"May be used as part of multimodal analgesia in cancer pain, but not first-line.","evidence":"Limited"}]
Primary treatment for: Osteoarthritis
Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute pain, Familial adenomatous polyposis
📋 Drug Information
| Generic Name(s) | Celecoxib (200mg) |
| Brand Name | Celcox 200mg Capsule |
| Manufacturer | Lupin Ltd |
| Packaging / Form | strip of 10 capsules (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 20°C and 25°C (68°F to 77°F). Keep away from moisture and heat. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, which is induced by inflammatory stimuli and responsible for producing prostaglandins that cause pain, inflammation, and fever. By blocking COX-2, it reduces these symptoms with less impact on COX-1, which is constitutively expressed in the stomach and platelets. This selectivity decreases, but does not eliminate, the risk of gastrointestinal ulceration and bleeding compared to non-selective NSAIDs.
Mechanism Steps
💡 How to Take Celcox 200mg Capsule
Strength: 200 mg immediate-release capsule
Dosage Information
| Adult Dosage | The usual adult dose for osteoarthritis is 200 mg once daily or 100 mg twice daily. For rheumatoid arthritis, the usual dose is 100 mg to 200 mg twice daily. For ankylosing spondylitis, the usual dose is 200 mg once daily or 100 mg twice daily. For acute pain, the initial dose is 400 mg, followed by 200 mg if needed on the first day, then 200 mg twice daily as needed. For familial adenomatous polyposis, the usual dose is 400 mg twice daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be at increased risk of cardiovascular, gastrointestinal, and kidney adverse effects. Use the lowest effective dose for the shortest duration. No specific dose adjustment is recommended based on age alone, but individualization is necessary. |
| Renal Impairment | For patients with mild to moderate kidney impairment, no dose adjustment is needed. For severe kidney impairment (creatinine clearance <30 mL/min), use is not recommended. Consult a doctor for individualized dosing. |
| Hepatic Impairment | For patients with mild liver impairment (Child-Pugh Class A), no dose adjustment is needed. For moderate liver impairment (Child-Pugh Class B), reduce the dose by 50%. For severe liver impairment (Child-Pugh Class C), use is not recommended. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 400 mg for most indications, except for familial adenomatous polyposis where the dose is 400 mg twice daily (800 mg total daily). Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Celcox 200mg Capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Lithium | Major | |
| Fluconazole | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Aspirin | Moderate | |
| Antacids | Minor | |
| Omeprazole | Minor |
🚨 Major Interactions
- Warfarin
- ACE inhibitors and ARBs
- Diuretics
- Lithium
- Fluconazole
⚡ Moderate Interactions
- Corticosteroids
- SSRIs
- Aspirin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and can worsen stomach irritation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to celecoxib or sulfonamides","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Severe heart failure","Recent coronary artery bypass graft (CABG) surgery","Active gastrointestinal bleeding or peptic ulcer","Severe kidney disease","Severe liver disease","Pregnancy (third trimester)"]
⚠️ Warnings & Precautions
["This medicine may increase the risk of serious cardiovascular events. Use with caution in patients with cardiovascular risk factors.","This medicine can cause gastrointestinal bleeding, ulceration, and perforation, which can be fatal. Use with caution in patients with a history of peptic ulcer disease or GI bleeding.","This medicine can cause kidney injury. Use with caution in patients with kidney disease, heart failure, or dehydration.","This medicine can cause liver injury. Monitor liver function in patients with liver disease.","This medicine may cause fluid retention and edema. Use with caution in patients with heart failure or hypertension.","This medicine may cause severe skin reactions. Discontinue at the first sign of rash or other allergic reaction.","This medicine should not be used in patients with known sulfonamide allergy.","This medicine may mask signs of infection, such as fever.","This medicine should be used with caution in the elderly, who are at higher risk of adverse effects.","This medicine should not be used during pregnancy unless clearly needed."]
🤱 Lactation Safety
This medicine is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, stomach pain, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, and cardiovascular events. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be considered if the overdose is recent. Hemodialysis is not effective in removing celecoxib.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol while on this medicine as it increases the risk of gastrointestinal bleeding. Inform your doctor if you have a history of heart disease, high blood pressure, kidney or liver problems, or stomach ulcers. Do not take other NSAIDs (like ibuprofen, naproxen, or aspirin) concurrently unless specifically instructed. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Store at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of cardiovascular, gastrointestinal, and kidney side effects. Use the lowest effective dose for the shortest duration. Regular monitoring of kidney and liver function, blood pressure, and signs of bleeding is recommended.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester, as it may cause premature closure of the ductus arteriosus. If you are planning pregnancy, consult your doctor to discuss alternative treatments. Use effective contraception while on this medicine.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain, but it is contraindicated after coronary artery bypass graft (CABG) surgery. Consult your surgeon before using this medicine after any surgery. It may increase the risk of bleeding and kidney problems.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may increase the risk of bleeding. Your dentist may recommend stopping it temporarily or taking precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or fatigue. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. Low-impact exercises are generally safe and beneficial for joint health.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not significantly impact your ability to work if you follow your doctor's instructions and manage side effects.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, especially if you have been on long-term therapy. Your doctor may taper the dose or switch you to another medicine. If you experience serious side effects, seek immediate medical attention and follow your doctor's advice.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of serious cardiovascular events, gastrointestinal bleeding, kidney injury, and liver toxicity. Regular monitoring of blood pressure, kidney function, and liver function is recommended. Use the lowest effective dose for the shortest duration possible. Discuss with your doctor if you need to use this medicine for more than a few weeks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay help with pain relief in some patients.
Evidence: ModerateReduces stress on weight-bearing joints and improves osteoarthritis symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the immune response to vaccines. Consult your doctor about the timing of vaccinations while on this medicine. It is not known to interact with most vaccines, but live vaccines should be avoided if you are on immunosuppressive therapy.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue your regular dosing schedule as closely as possible. Check local customs regulations for carrying prescription medicines. Carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts relieving pain within 30 to 60 minutes, but full anti-inflammatory effects may take several days to weeks of regular use.
A: Yes, taking it with food or milk is recommended to reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Long-term use may increase the risk of cardiovascular and gastrointestinal side effects. It should be used at the lowest effective dose for the shortest duration, with regular monitoring by your doctor.
A: It is best to avoid alcohol as it can increase the risk of stomach bleeding and irritation.
🤔 Common Patient Concerns
🔄 Substitutes for Celcox 200mg Capsule
View AllAlternative brands with exact same active ingredient:
-
Orthocel 200mg TabletBiochem Pharmaceutical Industries ₹37.13 6.7% COSTLIER
-
J Flex 200mg CapsuleVeritaz Healthcare Ltd ₹47.60 36.8% COSTLIER
-
Celira 200mg CapsuleShreya Life Sciences Pvt Ltd ₹56.25 61.6% COSTLIER
-
Celedol 200 CapsuleIpca Laboratories Ltd ₹57.75 65.9% COSTLIER
-
Celib 200mg CapsuleTorrent Pharmaceuticals Ltd ₹62.44 79.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is completely safe for the stomach.
Fact: While it has a lower risk of stomach ulcers than non-selective NSAIDs, it can still cause gastrointestinal bleeding and ulceration. - Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription-only medicine and should only be taken under medical supervision. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine is not recommended during pregnancy, especially in the third trimester, as it may harm the fetus.
🔄 Alternative Options
Generic Alternatives
- Celecoxib
Brand Alternatives
- Celebrex
- Cobix
- Zycel