carnozol 20 mg/75 mg capsule - Uses, Price, Side Effects & Substitutes
What is carnozol 20 mg/75 mg capsule used for?
Carnozol (Rabeprazole + Zinc Carnosine) is used to treat GASTRO INTESTINAL. It contains Rabeprazole (20mg) + Zinc Carnosine (75mg), which Rabeprazole irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reduci. Always consult your doctor before use. Take as prescribed.
- Generic Name: Rabeprazole + Zinc Carnosine
- Manufacturer: Tablets India Limited
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ carnozol 20 mg/75 mg capsule Uses & Benefits
Gastric ulcers, duodenal ulcers, gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, Helicobacter pylori eradication (as part of combination therapy).
Off-label uses: Stress ulcer prophylaxis, non-erosive reflux disease, functional dyspepsia.
๐ Drug Information
| Generic Name(s) | Rabeprazole + Zinc Carnosine |
| Brand Name | Carnozol |
| Manufacturer | Tablets India Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Proton Pump Inhibitor + Mucosal Protective Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Rabeprazole irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reducing gastric acid secretion. Zinc Carnosine promotes mucosal healing and protects gastric mucosa by forming a protective barrier and stimulating prostaglandin synthesis.
Mechanism Steps
๐ก How to Take carnozol 20 mg/75 mg capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of carnozol 20 mg/75 mg capsule
โ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Constipation
- Flatulence
๐จ Serious Side Effects
- Clostridium difficile-associated diarrhea
- Fractures (hip, wrist, spine)
- Hypomagnesemia
- Vitamin B12 deficiency
- Acute interstitial nephritis
- Cutaneous lupus erythematosus
โ ๏ธ Rare Side Effects
- Hepatic encephalopathy
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Agranulocytosis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Atazanavir | Major | Reduced absorption of atazanavir |
| Rilpivirine | Major | Reduced absorption of rilpivirine |
| Methotrexate | Major | Increased methotrexate toxicity |
| Cilostazol | Major | Increased cilostazol exposure |
| Clopidogrel | Major | Reduced clopidogrel efficacy |
| Warfarin | Moderate | Increased INR |
| Diazepam | Moderate | Increased diazepam levels |
| Phenytoin | Moderate | Increased phenytoin levels |
| Digoxin | Moderate | Increased digoxin levels |
| Iron salts | Moderate | Reduced iron absorption |
| Sucralfate | Minor | Reduced absorption of rabeprazole |
| Ketoconazole | Minor | Reduced ketoconazole absorption |
| Itraconazole | Minor | Reduced itraconazole absorption |
๐จ Major Interactions
- Atazanavir
- Rilpivirine
- Methotrexate
- Cilostazol
- Clopidogrel
โก Moderate Interactions
- Warfarin
- Diazepam
- Phenytoin
- Digoxin
- Iron salts
โน๏ธ Minor Interactions
- Sucralfate
- Ketoconazole
- Itraconazole
๐ฝ๏ธ Food Interactions
Food may delay absorption of rabeprazole; Zinc Carnosine absorption may be affected by food.
๐ท Alcohol Interaction
Alcohol may increase gastric irritation; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to rabeprazole, zinc carnosine, or any component; concurrent use with atazanavir or rilpivirine.
๐ Monitoring Parameters
Symptoms of GI bleeding, liver function tests, renal function, magnesium levels (long-term use).
๐คฑ Lactation Safety
Rabeprazole is excreted in breast milk; Zinc Carnosine: unknown. Avoid or use with caution.
๐ Overdose Management
Supportive care; no specific antidote. Hemodialysis not effective.
โฐ Missed Dose
Take as soon as remembered. If near next dose, skip missed dose. Do not double dose.