ambrolite d syrup - Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) medicine

Asthakind-DX Syrup Sugar Free: Complete Medicine Guide

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🏭 Tablets India Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of common cold and allergic rhinitis.
Reviewed by
SaathiMed Expert Panel | Sep 22, 2026

When to Call Your Doctor IMMEDIATELY

  • Fast, irregular, or pounding heartbeat
  • Difficulty breathing or swallowing
  • Swelling of face, lips, tongue, or throat
  • Severe dizziness or fainting
  • Confusion, hallucinations, or seizures
  • Difficulty urinating or no urine output
  • Severe headache with visual changes

If experiencing severe symptoms, call emergency services immediately.

What is ambrolite d syrup used for?

This medicine is a sugar-free syrup containing phenylephrine and chlorpheniramine maleate, used to relieve nasal congestion, runny nose, sneezing, and watery eyes due to colds or allergies. It works by narrowing blood vessels in the nose and blocking histamine. It may cause drowsiness, so avoid driving. Do not use for more than 7 days without consulting a doctor.

  • Generic Name: Phenylephrine + Chlorpheniramine Maleate
  • Manufacturer: Tablets India Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ambrolite d syrup के बारे में (Hindi Summary)

उपयोग: यह दवा सर्दी-जुकाम और एलर्जी से होने वाली नाक बंद, बहती नाक, छींक और आंखों में पानी जैसी समस्याओं में राहत देती है। यह शुगर-फ्री सिरप है, इसलिए डायबिटीज वाले मरीज भी इसका इस्तेमाल कर सकते हैं। इसमें फेनिलएफ्रिन नाक की बंदी को कम करता है और क्लोरफेनिरामाइन एलर्जी के लक्षणों को कम करता है।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, सिरदर्द और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। अगर दिल की धड़कन तेज हो, पेशाब करने में दिक्कत हो, या चेहरे, होंठ या गले में सूजन आए तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर की सलाह के बिना 7 दिन से ज्यादा न लें। इससे नींद आ सकती है, इसलिए गाड़ी चलाने या मशीन चलाने से बचें। शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। अगर आपको हाई ब्लड प्रेशर, दिल की बीमारी, डायबिटीज, ग्लूकोमा या प्रोस्टेट की समस्या है तो डॉक्टर से पूछकर ही लें। बच्चों को 6 साल से कम उम्र में न दें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ambrolite d syrup Uses & Benefits

[{"condition":"Common cold","description":"Relieves nasal congestion, runny nose, sneezing, and watery eyes associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces symptoms of seasonal or perennial allergic rhinitis, including sneezing, rhinorrhea, and nasal itching.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps relieve nasal congestion and pressure in sinusitis.","evidence":"Supportive"},{"condition":"Upper respiratory tract allergy","description":"Provides symptomatic relief from allergic reactions affecting the upper respiratory tract.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Common cold and allergic rhinitis

Also treats: Sinusitis, Upper respiratory tract allergy

📋 Drug Information

Generic Name(s)Phenylephrine + Chlorpheniramine Maleate
Brand NameAscoril D Plus Syrup Sugar Free
ManufacturerTablets India Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassDecongestant + Antihistamine
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not refrigerate. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk if it upsets your stomach.
2
Avoid driving or operating machinery until you know how this medicine affects you.
3
Do not use this medicine for more than 7 days without consulting a doctor.
4
Stay well hydrated to help thin mucus and relieve congestion.
5
Do not combine with other cold or allergy medicines without checking with your doctor.
6
If you have high blood pressure, monitor it regularly while taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Nasal congestion
This medicine is commonly prescribed for this.
Likely Use
Runny nose
This medicine helps dry up secretions.
Likely Use
Sneezing
This medicine blocks histamine to reduce sneezing.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Chest congestion
This medicine targets upper respiratory symptoms, not chest congestion.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPhenylephrine is absorbed from the gastrointestinal tract, but its oral bioavailability is low due to extensive first-pass metabolism. Chlorpheniramine maleate is well absorbed from the gastrointestinal tract.
DistributionPhenylephrine distributes widely into body tissues. Chlorpheniramine maleate is widely distributed and crosses the blood-brain barrier, which contributes to its sedative effects.
Protein BindingPhenylephrine protein binding is not well established. Chlorpheniramine maleate is approximately 70% bound to plasma proteins.
MetabolismPhenylephrine undergoes extensive first-pass metabolism in the liver and gut wall, primarily by monoamine oxidase and sulfation. Chlorpheniramine maleate is metabolized in the liver, mainly by CYP2D6 and CYP3A4.
Half-LifeThe elimination half-life of phenylephrine is approximately 2.5 to 3 hours. The elimination half-life of chlorpheniramine maleate is approximately 12 to 43 hours, with an average of about 20 hours.
ExcretionPhenylephrine and its metabolites are excreted primarily in the urine. Chlorpheniramine maleate and its metabolites are excreted mainly in the urine.
BioavailabilityThe oral bioavailability of phenylephrine is low, approximately 38% due to first-pass metabolism. The oral bioavailability of chlorpheniramine maleate is approximately 25% to 50%.
Onset of ActionPhenylephrine: onset of decongestant effect within 15 to 30 minutes after oral administration. Chlorpheniramine maleate: onset of antihistamine effect within 30 to 60 minutes.
Peak Plasma TimePhenylephrine: peak plasma concentration occurs within 1 to 2 hours. Chlorpheniramine maleate: peak plasma concentration occurs within 2 to 6 hours.
Duration of ActionPhenylephrine: decongestant effect lasts about 4 to 6 hours. Chlorpheniramine maleate: antihistamine effect lasts about 4 to 6 hours, but sedation may last longer.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Phenylephrine is a selective alpha-1 adrenergic receptor agonist that causes vasoconstriction of nasal blood vessels, reducing swelling and congestion. Chlorpheniramine maleate is a first-generation histamine H1-receptor antagonist that blocks histamine from binding to H1 receptors, thereby reducing allergic symptoms such as sneezing, itching, and runny nose. It also has anticholinergic properties that contribute to drying of secretions.

Mechanism Steps

1
Alpha-1 adrenergic receptor activation: Phenylephrine binds to alpha-1 adrenergic receptors on vascular smooth muscle in the nasal mucosa, causing vasoconstriction.
2
Reduced nasal congestion: Vasoconstriction decreases blood flow and fluid exudation in the nasal passages, reducing swelling and congestion.
3
Histamine H1 receptor blockade: Chlorpheniramine maleate competes with histamine for H1 receptor sites on effector cells, preventing histamine-mediated allergic symptoms.
4
Anticholinergic effect: Chlorpheniramine maleate also exhibits anticholinergic activity, which reduces secretions and helps dry up a runny nose.

💡 How to Take ambrolite d syrup

Strength: Each 5 mL of sugar-free syrup contains Phenylephrine 5 mg and Chlorpheniramine Maleate 2 mg.

1Shake the bottle well before each use.
2Use a measuring cup or spoon to measure the dose accurately.
3Take the medicine orally, with or without food.
4If stomach upset occurs, take with food or milk.
5Do not exceed the recommended dose or frequency.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5 to 10 mL (one to two teaspoons) every 4 to 6 hours as needed, not to exceed 6 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 6 years of age.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and consider a lower dose. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor.
Maximum Daily DoseFor adults: maximum 60 mL (12 teaspoons) in 24 hours. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases drowsiness and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ambrolite d syrup

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If drowsiness is excessive, consult your doctor.
Dry mouth, nose, or throat (Common (5-15%))
Sip water frequently or use sugar-free lozenges. If persistent, consult your doctor.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid sudden movements.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.
Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.

🚨 Serious Side Effects

Fast or irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations or irregular heartbeat.
Difficulty urinating (Rare (<0.1%))
Consult a doctor if you have trouble passing urine.
Severe allergic reaction (anaphylaxis) (Very rare (<0.01%))
Call emergency services if you experience swelling of face, lips, tongue, or throat, difficulty breathing, or severe rash.
Hallucinations or confusion (Rare (<0.1%))
Discontinue and seek medical advice if you experience confusion or hallucinations.

⚠️ Rare Side Effects

Blood dyscrasias (e.g., hemolytic anemia, thrombocytopenia)
Report unusual bleeding, bruising, or fatigue to your doctor.
Seizures
Seek immediate medical attention if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Tricyclic antidepressants Major
Beta-blockers Major
CNS depressants Moderate
Anticholinergics Moderate
CYP2D6 inhibitors Moderate
Antacids Minor
Digoxin Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Beta-blockers

⚡ Moderate Interactions

  • CNS depressants (e.g., alcohol, sedatives, opioids)
  • Anticholinergic drugs (e.g., atropine, benztropine)
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)

🍷 Alcohol Interaction

Alcohol increases the sedative and drowsiness effects of chlorpheniramine maleate. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to phenylephrine, chlorpheniramine, or any component of the formulation.","Severe hypertension or coronary artery disease.","Narrow-angle glaucoma.","Urinary retention or prostatic hypertrophy.","Use in premature infants and neonates.","Concurrent use with MAOIs or within 14 days of stopping MAOIs."]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until effects are known.","Avoid alcohol and other CNS depressants.","Use with caution in patients with hypertension, cardiovascular disease, diabetes, thyroid disorders, glaucoma, or prostate enlargement.","Do not exceed recommended dose or duration of use (maximum 7 days without medical advice).","Sugar-free formulation: contains sorbitol or other sugar alcohols; may cause laxative effect if consumed in large amounts.","Consult a doctor before use in pregnancy or breastfeeding."]

🤱 Lactation Safety

Phenylephrine and chlorpheniramine maleate may pass into breast milk. Chlorpheniramine may cause drowsiness in the nursing infant. Consult a doctor before use during breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, dizziness, confusion, fast heartbeat, hallucinations, seizures, or difficulty breathing. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Do not exceed the recommended dose of this medicine. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness. Do not drink alcohol while taking this medicine because it can increase drowsiness and dizziness. If you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or prostate enlargement, consult your doctor before using this medicine. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. Pregnant or breastfeeding women should consult a doctor before use.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the side effects of this medicine, especially drowsiness, dizziness, confusion, and urinary retention. Use with caution and consider a lower dose. Consult a doctor before use.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Phenylephrine and chlorpheniramine may not be safe for the baby.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may interact with anesthetics or other medications and affect blood pressure and heart rate.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it can cause dry mouth and may interact with medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Use a humidifier to keep nasal passages moist.
😴
Get adequate rest to help your body recover.
💧
Avoid allergens such as dust, pollen, and pet dander.
🧘
Practice good hand hygiene to prevent infections.
🌞
Avoid smoking and exposure to secondhand smoke.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Drink warm fluids like soups and herbal teas.
Include vitamin C-rich foods such as oranges and bell peppers.
Avoid cold and sugary drinks that can worsen congestion.
Eat light, easily digestible meals.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. Avoid these activities until you know how the medicine affects you. It may also cause dry mouth, so keep water handy.

🛑 When to Stop This Medicine

Stop taking this medicine and consult a doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as fast heartbeat, difficulty urinating, or allergic reactions.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of phenylephrine nasal decongestants can lead to rebound congestion. Chlorpheniramine may cause persistent drowsiness and anticholinergic effects. Use only for short-term relief (up to 7 days) unless directed by a doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps clear nasal passages and reduce congestion without medication.

Evidence: Well-established
Steam inhalation

Can temporarily relieve nasal congestion.

Evidence: Supportive
Antihistamine nasal sprays

Alternative for allergic rhinitis with fewer systemic side effects.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever or active infection, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Do not leave it in a hot car.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She started this medicine as prescribed for her runny nose and sneezing. Within 30 minutes, her symptoms improved significantly. She experienced mild drowsiness, so she took it at bedtime. She emphasized not driving after taking it.
💡 Lesson: This medicine effectively relieves allergy symptoms but can cause drowsiness; taking it at night may help manage this side effect.
👤 A 50-year-old man with diabetes and common cold
He was prescribed this sugar-free syrup for nasal congestion. He appreciated that it did not affect his blood sugar levels. He took it every 6 hours as needed and found relief within a day. He made sure not to exceed the recommended dose.
💡 Lesson: Sugar-free formulations are suitable for diabetics, but still require adherence to dosage and duration guidelines.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving symptoms within 30 to 60 minutes after taking a dose.

Q: Can I take this medicine at night?

A: Yes, but it may cause drowsiness, so it is often taken at bedtime to help with sleep while relieving symptoms.

Q: Is this medicine safe for diabetics?

A: Yes, this sugar-free formulation is suitable for diabetics, but always consult your doctor before use.

Q: How often can I take this medicine?

A: Adults can take 5-10 mL every 4-6 hours as needed, not exceeding 6 doses in 24 hours.

Q: Can I take this medicine with other cold medicines?

A: Do not take with other medicines containing phenylephrine or chlorpheniramine without consulting your doctor, as it may lead to overdose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my blood sugar levels?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ambrolite d syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take this medicine for weeks.
    Fact: This medicine should not be used for more than 7 days without medical advice due to risk of side effects and rebound congestion.
  • Myth: Since it is sugar-free, it is safe for everyone.
    Fact: Sugar-free does not mean it is safe for all; it still has active ingredients that can cause side effects and interact with other medicines.

🔄 Alternative Options

Generic Alternatives

  • Phenylephrine + Chlorpheniramine Maleate Syrup (sugar-free)

Brand Alternatives

  • Asthakind-DX Syrup Sugar Free

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Phenylephrine 5mg/5ml + Chlorpheniramine Maleate 2mg/5ml","key_feature":"Sugar-free, decongestant + antihistamine"},{"medicine":"Phenylephrine + Cetirizine","composition":"Phenylephrine + Cetirizine","key_feature":"Less sedating antihistamine"},{"medicine":"Chlorpheniramine alone","composition":"Chlorpheniramine Maleate","key_feature":"Antihistamine only, no decongestant"}]

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