Calcileap Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe nausea, vomiting, or abdominal pain
- Confusion, drowsiness, or coma
- Irregular heartbeat or palpitations
- Increased thirst and frequent urination
- Muscle weakness or bone pain
- Blood in urine or severe flank pain
- Swelling of face, lips, or throat
If experiencing severe symptoms, call emergency services immediately.
What is calcijet injection used for?
This medicine is an injectable form of calcitriol, the active form of vitamin D3. It is used to treat low calcium levels and secondary hyperparathyroidism in patients with chronic kidney disease. It works by helping the body absorb calcium and reducing parathyroid hormone levels. It must be given by a healthcare professional and requires regular blood tests to monitor calcium levels.
- Generic Name: Calcitriol
- Manufacturer: LG Lifesciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 calcijet injection के बारे में (Hindi Summary)
उपयोग: यह दवा कैल्सिट्रियोल का इंजेक्शन है, जो विटामिन डी3 का सक्रिय रूप है। इसका उपयोग गुर्दे की बीमारी वाले रोगियों में कैल्शियम की कमी और पैराथायरॉइड हार्मोन के बढ़ने के इलाज के लिए किया जाता है। यह शरीर में कैल्शियम के अवशोषण को बढ़ाता है और हड्डियों को मजबूत बनाता है। यह इंजेक्शन डॉक्टर द्वारा मांसपेशी में लगाया जाता है। इसका उपयोग डॉक्टर की सलाह के बिना न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, कब्ज, अधिक प्यास लगना, बार-बार पेशाब आना, मांसपेशियों में कमजोरी और थकान शामिल हैं। कभी-कभी रक्त में कैल्शियम का स्तर बहुत अधिक बढ़ सकता है, जिससे भ्रम, दिल की धड़कन अनियमित होना, और गुर्दे की पथरी जैसी गंभीर समस्याएं हो सकती हैं। अगर आपको ऐसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा ही लगाई जानी चाहिए। खुद से इंजेक्शन न लगाएं। इलाज के दौरान डॉक्टर नियमित रूप से रक्त में कैल्शियम और फॉस्फेट की जांच करेंगे। बिना डॉक्टर की सलाह के कैल्शियम या विटामिन डी की अतिरिक्त खुराक न लें। पर्याप्त पानी पिएं। अगर आपको मतली, उल्टी, कब्ज, या बार-बार पेशाब आने जैसे लक्षण हों तो डॉक्टर को बताएं।
💊 calcijet injection Uses & Benefits
[{"condition":"Secondary hyperparathyroidism in chronic kidney disease","description":"This medicine helps lower parathyroid hormone levels and improves calcium balance in patients with kidney failure who cannot activate vitamin D normally.","evidence":"Well-established"},{"condition":"Hypocalcemia in chronic kidney disease","description":"It raises serum calcium by increasing intestinal calcium absorption and mobilizing calcium from bone.","evidence":"Well-established"},{"condition":"Vitamin D-dependent rickets or osteomalacia","description":"Used when the body cannot convert vitamin D to its active form, helping to mineralize bone and correct low calcium.","evidence":"Well-established"},{"condition":"Hypoparathyroidism","description":"This medicine can help maintain normal calcium levels when the parathyroid glands do not produce enough hormone.","evidence":"Established"},{"condition":"Osteoporosis in patients with kidney disease","description":"It may be used as part of a bone-protection strategy, though it is not a first-line treatment for common postmenopausal osteoporosis.","evidence":"Limited"}]
Off-label uses: [{"condition":"Psoriasis","description":"Topical calcitriol is used for psoriasis, but the injectable form is not standard for this condition.","evidence":"Limited"},{"condition":"Prevention of corticosteroid-induced osteoporosis","description":"Sometimes used off-label, but other agents are preferred.","evidence":"Limited"}]
Primary treatment for: Secondary hyperparathyroidism in chronic kidney disease
Also treats: Hypocalcemia, Vitamin D-dependent rickets, Osteomalacia, Hypoparathyroidism
📋 Drug Information
| Generic Name(s) | Calcitriol |
| Brand Name | Calcirol 600000IU Injection |
| Manufacturer | LG Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Vitamins |
| Route of Administration | Intramuscular injection. This medicine must be administered by a healthcare professional |
| Storage | Store in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Keep in the original carton until use. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture. Check the expiry date on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is the active form of vitamin D3. It binds to the vitamin D receptor inside target cells, forming a complex that enters the nucleus and regulates the expression of genes involved in calcium and phosphate transport. In the intestine, it increases the production of calcium-binding proteins that carry calcium from the gut into the blood. In bone, it helps mobilize calcium when needed and supports normal bone remodeling. In the kidney, it reduces calcium loss in urine. In the parathyroid glands, it directly suppresses parathyroid hormone production, which is helpful in secondary hyperparathyroidism. Overall, this medicine restores calcium balance and reduces the harmful effects of high parathyroid hormone levels.
Mechanism Steps
💡 How to Take calcijet injection
Strength: 1 mcg per injection (1 microgram)
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, the patient's calcium and parathyroid hormone levels, kidney function, and response to treatment. For secondary hyperparathyroidism in chronic kidney disease, a typical starting dose might be 0.5 mcg to 1 mcg given intramuscularly two to three times per week, but this varies widely. Your doctor will adjust the dose based on regular blood tests. Never self-administer this injection. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially regarding hypercalcemia. Doses should be carefully adjusted, and calcium levels monitored more frequently. |
| Renal Impairment | Patients with kidney disease require careful monitoring of calcium and phosphate levels. The dose should be individualized based on kidney function and response. This medicine is often used in chronic kidney disease, but close supervision is necessary. |
| Hepatic Impairment | Patients with liver disease may have impaired metabolism of calcitriol. Dose adjustment may be necessary, and monitoring of calcium levels is recommended. |
| Maximum Daily Dose | The maximum daily dose is not fixed and must be determined by a clinician based on individual response and calcium levels. Exceeding the prescribed dose can cause severe hypercalcemia. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of calcijet injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Thiazide diuretics | Major | |
| Digoxin | Major | |
| Calcium supplements | Major | |
| Vitamin D supplements | Major | |
| Corticosteroids | Moderate | |
| Ketoconazole | Moderate | |
| Cholestyramine | Moderate | |
| Magnesium-containing antacids | Minor | |
| Orlistat | Minor | |
| Phenytoin | Moderate |
🚨 Major Interactions
- Thiazide diuretics
- Digoxin
- Calcium-containing supplements
- Vitamin D supplements
⚡ Moderate Interactions
- Corticosteroids
- Ketoconazole
- Cholestyramine
🍷 Alcohol Interaction
Alcohol may worsen bone loss and increase the risk of falls. It is advisable to limit alcohol consumption while receiving this medicine, especially if you have kidney disease or osteoporosis.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypercalcemia (high blood calcium)","Vitamin D toxicity","Known hypersensitivity to calcitriol or any component of the injection","Evidence of digitalis toxicity"]
⚠️ Warnings & Precautions
["This medicine can cause hypercalcemia; monitor calcium levels closely.","Avoid concurrent use of other vitamin D supplements or calcium supplements unless prescribed.","Use with caution in patients with kidney stones or a history of kidney stones.","Patients with heart disease should be monitored for arrhythmias.","This medicine should be used with caution in patients with sarcoidosis or other granulomatous diseases, as they may have increased sensitivity to vitamin D.","Do not use this medicine if you have high calcium levels or vitamin D toxicity.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","This medicine may impair your ability to drive or operate machinery if you experience dizziness or drowsiness."]
🤱 Lactation Safety
Calcitriol is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose of this medicine can cause severe hypercalcemia, which may be life-threatening. Symptoms include nausea, vomiting, confusion, weakness, and irregular heartbeat. Treatment includes immediate discontinuation of the medicine, hydration with intravenous fluids, and possibly medications such as corticosteroids or bisphosphonates to lower calcium levels. Hemodialysis may be considered in severe cases. Seek emergency medical attention immediately if overdose is suspected.
⏰ Missed Dose
If you miss a scheduled injection, contact your healthcare provider as soon as possible. Do not attempt to self-administer a double dose. Your doctor will advise you on the next steps based on your treatment schedule.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional. Do not attempt to self-administer this injection. Your doctor will check your blood calcium, phosphate, and parathyroid hormone levels before and during treatment. Tell your doctor if you have ever had kidney stones, heart disease, sarcoidosis, or any condition that raises your calcium levels. Avoid taking extra vitamin D or calcium supplements unless your doctor specifically tells you to. Drink plenty of water to help prevent kidney stones. Report any symptoms of high calcium such as nausea, vomiting, constipation, increased thirst, or frequent urination immediately. If you miss a scheduled injection, contact your clinic for advice; do not try to catch up on your own. Keep all follow-up appointments for blood tests. Inform any other doctor treating you that you are receiving this medicine, especially before surgery or dental work.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to hypercalcemia and its complications. Doses should be started low and increased gradually with close monitoring.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor. This medicine is Category C and should be used during pregnancy only if clearly needed. Discuss risks and benefits.
🏥 Post-Surgery Considerations
After surgery, inform your surgeon and anesthesiologist that you are receiving this medicine. It may affect calcium levels during recovery.
🦷 Dental Procedures
Inform your dentist that you are on this medicine. It may affect bone healing and calcium levels. Your dentist may consult with your doctor before procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe, but if you have bone pain or muscle weakness, avoid high-impact activities. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it should not interfere with your daily activities.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping suddenly can cause calcium levels to drop or parathyroid hormone to rise. Your doctor will decide when and how to stop based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of calcium, phosphate, and parathyroid hormone levels. Prolonged hypercalcemia can lead to kidney stones, kidney damage, and soft tissue calcification. Your doctor will adjust the dose to maintain safe levels. Regular follow-up is essential.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Oral forms are available and may be used if appropriate.
Evidence: Well-establishedParicalcitol or doxercalciferol may be alternatives.
Evidence: Well-establishedA calcimimetic that lowers parathyroid hormone, used in some patients.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, inform your doctor before any vaccination.
📦 Storage Guide
✅ DO
Store in refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Keep in original carton to protect from light
❌ DON'T
Do not transfer to another container
✅ DO
Check expiry date before use
❌ DON'T
Do not use if expired
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label. Keep it refrigerated during travel using a cool pack. Carry a copy of your prescription. If traveling across time zones, consult your doctor about adjusting the injection schedule. Declare it at customs if required. Do not expose to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effects on parathyroid hormone and calcium may be seen within days to weeks, but the full benefit takes longer. Your doctor will monitor your levels regularly.
A: No, this medicine must be given by a healthcare professional.
A: Avoid extra calcium and vitamin D supplements unless prescribed. Limit alcohol.
🤔 Common Patient Concerns
🔄 Substitutes for calcijet injection
View AllAlternative brands with exact same active ingredient:
-
calcileap injectionGenix Lifescience Pvt Ltd ₹129.00 7% COSTLIER
-
laretol 1mcg injectionLa Renon Healthcare Pvt Ltd ₹141.56 17.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a general vitamin D supplement.
Fact: This medicine is the active form of vitamin D and is much more potent than regular vitamin D supplements. It should only be used under medical supervision. - Myth: You can self-administer this injection at home.
Fact: This medicine must be given by a healthcare professional. Self-administration is not recommended. - Myth: More is better for bone health.
Fact: Taking too much can cause dangerous high calcium levels. The dose must be carefully adjusted by a doctor.
🔄 Alternative Options
Generic Alternatives
- Calcitriol injection (generic)
Brand Alternatives
- Calcijex
- Rocaltrol
- Zemplar