bonotiode injection - Uses, Price, Side Effects & Substitutes
What is bonotiode injection used for?
Bonista Cartridge (Teriparatide) is used to treat HORMONES. It contains Teriparatide (750mcg), which Recombinant human parathyroid hormone (1-34) that stimulates osteoblast activity. Always consult your doctor before use. Take as prescribed.
- Generic Name: Teriparatide
- Manufacturer: LG Lifesciences
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ bonotiode injection Uses & Benefits
Treatment of osteoporosis in postmenopausal women at high risk of fracture; treatment of osteoporosis in men; treatment of glucocorticoid-induced osteoporosis.
Off-label uses: Hypoparathyroidism, Delayed fracture healing
๐ Drug Information
| Generic Name(s) | Teriparatide |
| Brand Name | Bonista Cartridge |
| Manufacturer | LG Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | HORMONES |
| Action Class | Bone formation stimulator -PTH analogue |
| Route of Administration | Subcutaneous injection |
| Storage | Store in refrigerator at 2ยฐC to 8ยฐC (36ยฐF to 46ยฐF); do not freeze; protect from light; discard after 28 days of first use. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Recombinant human parathyroid hormone (1-34) that stimulates osteoblast activity, increasing bone formation and bone mass.
Mechanism Steps
๐ก How to Take bonotiode injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bonotiode injection
โ Common Side Effects
- Nausea
- Dizziness
- Leg cramps
- Injection site reactions
- Arthralgia
- Headache
๐จ Serious Side Effects
- Osteosarcoma (rare, long-term)
- Hypercalcemia
- Orthostatic hypotension
- Renal impairment
โ ๏ธ Rare Side Effects
- Allergic reactions
- Transient chest pain
- Hyperuricemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Digoxin | Major | Hypercalcemia may increase digoxin toxicity; monitor serum calcium and digoxin levels. |
| Thiazide diuretics | Major | Increased risk of hypercalcemia; avoid concurrent use or monitor calcium closely. |
| Loop diuretics | Major | May increase calcium excretion; monitor calcium levels. |
| Corticosteroids | Major | May reduce bone formation effect; avoid chronic use. |
| Calcium supplements | Moderate | May increase risk of hypercalcemia; monitor calcium intake. |
| Vitamin D analogs | Moderate | May increase calcium absorption; monitor calcium levels. |
| Bisphosphonates | Moderate | May attenuate bone formation effect; sequential therapy recommended. |
| Selective estrogen receptor modulators | Moderate | Additive effect on bone density; monitor for hypercalcemia. |
| Antacids | Minor | May reduce absorption of calcium if taken together; separate by 2 hours. |
| Magnesium-containing products | Minor | No significant interaction; monitor magnesium if high doses used. |
๐จ Major Interactions
- Digoxin
- Thiazide diuretics
- Loop diuretics
- Corticosteroids
โก Moderate Interactions
- Calcium supplements
- Vitamin D analogs
- Bisphosphonates
- Selective estrogen receptor modulators
โน๏ธ Minor Interactions
- Antacids
- Magnesium-containing products
๐ฝ๏ธ Food Interactions
No significant food interactions; avoid high-calcium meals immediately before or after injection.
๐ท Alcohol Interaction
No known interaction; moderate consumption unlikely to affect therapy.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to teriparatide, Paget's disease of bone, unexplained alkaline phosphatase elevation, prior radiation therapy to skeleton, bone metastases, hypercalcemia, severe renal impairment, pregnancy.
๐ Monitoring Parameters
Serum calcium, alkaline phosphatase, bone mineral density, renal function, urine calcium.
๐คฑ Lactation Safety
Not recommended; unknown if excreted in human milk.
๐ Overdose Management
May cause hypercalcemia, nausea, vomiting, dizziness; treat symptomatically; monitor serum calcium; consider hydration and loop diuretics if severe.
โฐ Missed Dose
If a dose is missed, administer as soon as remembered; do not double dose; resume normal schedule the next day.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for bonotiode injection
View AllAlternative brands with exact same active ingredient (Teriparatide (750mcg)):
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bonmax pth 750mcg autopenZydus Cadila โน2,999.00 190.8% COSTLIER
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tricium pth injectionCorona Remedies Pvt Ltd โน5,445.00 428% COSTLIER
-
terifrac injectionIntas Pharmaceuticals Ltd โน5,500.00 433.3% COSTLIER
-
bonspark injectionIntegrace Pvt Ltd โน7,031.25 581.8% COSTLIER
-
terifort 750mcg solution for injectionIpca Laboratories Ltd โน7,500.00 627.3% COSTLIER
-
osteofrac 750mcg injectionIntas Pharmaceuticals Ltd โน8,175.00 692.7% COSTLIER
-
bonrange-pth injectionBiorange Biologicals Private Limited โน8,906.25 763.6% COSTLIER
-
bonmax pth 750mcg solution for injectionZydus Cadila โน9,159.00 788.1% COSTLIER
-
zotide injectionCipla Ltd โน9,782.85 848.6% COSTLIER
-
osteri 750mcg solution for injectionEmcure Pharmaceuticals Ltd โน11,288.00 994.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.