bupraset 150mg tablet xr

4.5 (14 reviews)

Bupropion (150mg)

🏭 La Renon Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is bupraset 150mg tablet xr used for?

Atydep 150mg Tablet SR (Bupropion) is used to treat NEURO CNS. It contains Bupropion (150mg), which Weak inhibitor of neuronal reuptake of norepinephrine and dopamine; does not inh. Always consult your doctor before use. Take as prescribed.

Generic Name: Bupropion
Manufacturer: La Renon Healthcare Pvt Ltd
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 bupraset 150mg tablet xr Uses & Benefits

Major depressive disorder, seasonal affective disorder, smoking cessation.

Off-label uses: ADHD, bipolar depression, sexual dysfunction, obesity, neuropathic pain.

📋 Drug Information

Generic Name(s)	Bupropion
Brand Name	Atydep 150mg Tablet SR
Manufacturer	La Renon Healthcare Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Norepinephrine-dopamine reuptake inhibitor (NDRI)
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; peak plasma concentrations occur within 3 hours for immediate-release, but sustained-release formulation has slower absorption.

DistributionDistributed widely; crosses blood-brain barrier; volume of distribution approximately 20-30 L/kg.

Protein Binding82-88% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP2B6 to active metabolites (hydroxybupropion, threohydrobupropion, erythrohydrobupropion).

Half-LifeApproximately 21 hours for bupropion; 20-24 hours for hydroxybupropion.

ExcretionPrimarily renal (87%) as metabolites; 10% in feces.

BioavailabilityApproximately 80% for sustained-release formulation.

Onset of ActionTherapeutic effects may take 2-4 weeks; immediate effects on norepinephrine and dopamine reuptake oc

Peak Plasma Time3 hours for sustained-release formulation.

Duration of ActionSustained-release formulation provides therapeutic levels for 12-24 hours.

How It Works

Weak inhibitor of neuronal reuptake of norepinephrine and dopamine; does not inhibit serotonin reuptake or monoamine oxidase.

Mechanism Steps

1Bupropion binds to and inhibits the norepinephrine transporter (NET) and dopamine transporter (DAT) on presynaptic neurons.

2Inhibition of NET and DAT prevents reuptake of norepinephrine and dopamine into the presynaptic neuron.

3Increased extracellular concentrations of norepinephrine and dopamine in the synaptic cleft.

💡 How to Take bupraset 150mg tablet xr

Follow your doctor's prescription exactly.

⚠️ Side Effects of bupraset 150mg tablet xr

✅ Common Side Effects

Dry mouth
Insomnia
Headache
Nausea
Constipation
Dizziness
Sweating
Tremor
Anxiety
Agitation

🚨 Serious Side Effects

Seizures
Hypertension
Tachycardia
Allergic reactions (rash, urticaria, angioedema)
Psychiatric symptoms (hallucinations, paranoia, confusion)
Suicidal thoughts or behavior

⚠️ Rare Side Effects

Hepatotoxicity
Stevens-Johnson syndrome
Serotonin syndrome
Cardiac arrhythmias
Parkinsonism
Dyskinesia
Akathisia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
MAOIs	Major	Increased risk of hypertensive crisis
Selegiline	Major	Increased risk of serotonin syndrome
Linezolid	Major	Increased risk of serotonin syndrome
Methylene blue	Major	Increased risk of serotonin syndrome
Ritonavir	Major	Increased bupropion levels, toxicity
Lopinavir	Major	Increased bupropion levels, toxicity
Efavirenz	Major	Decreased bupropion levels, reduced efficacy
Carbamazepine	Major	Decreased bupropion levels, reduced efficacy
Phenobarbital	Major	Decreased bupropion levels, reduced efficacy
Phenytoin	Major	Decreased bupropion levels, reduced efficacy
Cimetidine	Moderate	Increased bupropion levels
Clopidogrel	Moderate	Increased bupropion levels
Orphenadrine	Moderate	Increased bupropion levels
Thiotepa	Moderate	Increased bupropion levels
Cyclophosphamide	Moderate	Increased bupropion levels
Tamoxifen	Moderate	Decreased bupropion levels
Citalopram	Moderate	Increased risk of seizures
Sertraline	Moderate	Increased risk of seizures
Fluoxetine	Moderate	Increased risk of seizures
Paroxetine	Moderate	Increased risk of seizures
Duloxetine	Moderate	Increased risk of seizures
Venlafaxine	Moderate	Increased risk of seizures
Amitriptyline	Moderate	Increased risk of seizures
Imipramine	Moderate	Increased risk of seizures
Nortriptyline	Moderate	Increased risk of seizures
Haloperidol	Moderate	Increased risk of seizures
Risperidone	Moderate	Increased risk of seizures
Olanzapine	Moderate	Increased risk of seizures
Clozapine	Moderate	Increased risk of seizures
Levodopa	Moderate	Increased risk of adverse effects
Amantadine	Moderate	Increased risk of adverse effects
Nicotine	Moderate	Increased blood pressure
Alcohol	Moderate	Increased risk of seizures and adverse effects
Caffeine	Minor	Increased stimulant effects
Theophylline	Minor	Increased stimulant effects
Warfarin	Minor	Possible altered anticoagulation
Digoxin	Minor	Possible altered digoxin levels
Beta-blockers	Minor	Possible increased blood pressure
ACE inhibitors	Minor	Possible increased blood pressure
Diuretics	Minor	Possible increased blood pressure

🚨 Major Interactions

MAOIs
Selegiline
Linezolid
Methylene blue
Ritonavir
Lopinavir
Efavirenz
Carbamazepine
Phenobarbital
Phenytoin

⚡ Moderate Interactions

Cimetidine
Clopidogrel
Orphenadrine
Thiotepa
Cyclophosphamide
Tamoxifen
Citalopram
Sertraline
Fluoxetine
Paroxetine
Duloxetine
Venlafaxine
Amitriptyline
Imipramine
Nortriptyline
Haloperidol
Risperidone
Olanzapine
Clozapine
Levodopa
Amantadine
Nicotine
Alcohol

ℹ️ Minor Interactions

Caffeine
Theophylline
Warfarin
Digoxin
Beta-blockers
ACE inhibitors
Diuretics

🍽️ Food Interactions

Food may delay absorption; high-fat meal may increase peak concentration.

🍷 Alcohol Interaction

Avoid alcohol; may increase risk of seizures and adverse effects.

🛡️ Safety & Warnings

🚫 Contraindications

Seizure disorder, current or prior diagnosis of bulimia or anorexia nervosa, abrupt discontinuation of alcohol or sedatives, MAOI use within 14 days, known hypersensitivity.

📊 Monitoring Parameters

Blood pressure, heart rate, mood changes, suicidal ideation, weight, seizure activity.

🤱 Lactation Safety

Excreted in breast milk; use with caution; monitor infant for agitation, poor feeding, and weight ga

💊 Overdose Management

Activated charcoal, supportive care; monitor for seizures, cardiac arrhythmias; no specific antidote.

⏰ Missed Dose

If missed, take as soon as remembered unless close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for bupraset 150mg tablet xr

View All

Alternative brands with exact same active ingredient (Bupropion (150mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.