anfoe 4000iu injection - Recombinant Human Erythropoietin Alfa (4000IU) medicine

anfoe 4000iu injection

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🏭 La Renon Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
🤰 Pregnancy Category A 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is anfoe 4000iu injection used for?

This medicine contains Recombinant Human Erythropoietin Alfa (4000IU) and is used to treat BLOOD RELATED. Stimulates erythropoiesis by binding to erythropoietin receptors on erythroid progenitor cells, prom. Always consult your doctor before use.

  • Generic Name: Recombinant Human Erythropoietin Alfa
  • Manufacturer: La Renon Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 anfoe 4000iu injection Uses & Benefits

Anemia in chronic kidney disease, anemia in cancer patients on chemotherapy, reduction of allogeneic blood transfusion in surgery, anemia in HIV patients treated with zidovudine.

Off-label uses: Anemia of prematurity, anemia in inflammatory bowel disease, myelodysplastic syndromes (selected cases).

📋 Drug Information

Generic Name(s)Recombinant Human Erythropoietin Alfa
Brand NameAnfoe 10000IU Injection
ManufacturerLa Renon Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassErythropoiesis-stimulating agent (ESA)
Route of AdministrationSubcutaneous or intravenous injection
StorageStore at 2-8°C (refrigerate). Do not freeze. Protect from light.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSubcutaneous: slow absorption; Intravenous: immediate
DistributionPrimarily in plasma; small volume of distribution
Protein BindingApproximately 50%
MetabolismPartially metabolized in liver
Half-LifeSubcutaneous: ~24 hours; Intravenous: ~4-13 hours
ExcretionPrimarily renal (small amount unchanged)
BioavailabilitySubcutaneous: ~20-30%
Onset of ActionSeveral days to weeks
Peak Plasma TimeSubcutaneous: 12-24 hours; Intravenous: immediate
Duration of ActionSeveral days

How It Works

Stimulates erythropoiesis by binding to erythropoietin receptors on erythroid progenitor cells, promoting their proliferation and differentiation into red blood cells.

Mechanism Steps

1Binds to erythropoietin receptor (EPO-R) on erythroid progenitor cells in bone marrow.
2Activates JAK2/STAT5 signaling pathway.
3Promotes survival, proliferation, and differentiation of erythroid progenitors.
4Increases red blood cell production and release into circulation.
5Elevates hemoglobin and hematocrit levels.

💡 How to Take anfoe 4000iu injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of anfoe 4000iu injection

✅ Common Side Effects

Hypertension
Headache
Arthralgia
Nausea
Diarrhea
Injection site pain

🚨 Serious Side Effects

Thromboembolic events (e.g., stroke, MI)
Pure red cell aplasia (PRCA)
Hypertensive encephalopathy
Seizures

⚠️ Rare Side Effects

Allergic reactions
Hyperkalemia
Porhyria
Tumor progression (theoretical)

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Androgens Major Increased erythropoiesis and risk of polycythemia
ACE inhibitors Major Reduced erythropoietin efficacy
Immunosuppressants Major Decreased erythropoietic response
Heparin Moderate Increased risk of thrombosis
Iron supplements Moderate Enhanced erythropoiesis when iron deficient
Antihypertensives Moderate May require dose adjustment due to blood pressure changes
Corticosteroids Minor Possible additive effect on erythropoiesis
Estrogens Minor Possible additive effect on erythropoiesis

🚨 Major Interactions

  • Androgens
  • ACE inhibitors
  • Immunosuppressants

⚡ Moderate Interactions

  • Heparin
  • Iron supplements
  • Antihypertensives

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Uncontrolled hypertension, known hypersensitivity to mammalian cell-derived products or albumin, pure red cell aplasia (PRCA) with prior erythropoietin therapy.

🤱 Lactation Safety

Not known if excreted in breast milk; caution advised

💊 Overdose Management

Monitor for hypertension and polycythemia; phlebotomy may be needed if hemoglobin exceeds target.

⏰ Missed Dose

Administer as soon as remembered; if close to next dose, skip missed dose and resume regular schedule. Do not double dose.

🔄 Substitutes for anfoe 4000iu injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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