brufit od 400 mg tablet
What is brufit od 400 mg tablet used for?
Acronil (Flupirtine) is used to treat PAIN ANALGESICS. It contains Flupirtine (400mg), which Selective neuronal potassium channel opener; indirect NMDA receptor antagonist. Always consult your doctor before use. Take as prescribed.
- Generic Name: Flupirtine
- Manufacturer: Abbott
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ brufit od 400 mg tablet Uses & Benefits
Acute and chronic pain, muscle spasms
Off-label uses: Neuropathic pain, fibromyalgia
๐ Drug Information
| Generic Name(s) | Flupirtine |
| Brand Name | Acronil |
| Manufacturer | Abbott |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Selective neuronal potassium channel openers (SNEPCO) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Selective neuronal potassium channel opener; indirect NMDA receptor antagonist
Mechanism Steps
๐ก How to Take brufit od 400 mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of brufit od 400 mg tablet
โ Common Side Effects
- Dizziness
- Drowsiness
- Nausea
- Constipation
- Dry mouth
๐จ Serious Side Effects
- Hepatotoxicity
- Liver failure
- Seizures
- Allergic reactions
โ ๏ธ Rare Side Effects
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Alcohol | Major | Enhanced sedation and hepatotoxicity |
| CNS depressants | Major | Additive sedation |
| MAO inhibitors | Major | Risk of hypertensive crisis |
| Antihypertensives | Moderate | Enhanced hypotensive effect |
| Diuretics | Moderate | Increased risk of electrolyte imbalance |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Antacids | Minor | Slight decrease in absorption |
| Cimetidine | Minor | Increased flupirtine levels |
๐จ Major Interactions
- Warfarin
- CNS depressants
- MAO inhibitors
โก Moderate Interactions
- Antihypertensives
- Diuretics
- Oral contraceptives
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
High-fat meals may delay absorption
๐ท Alcohol Interaction
Increased CNS depression and hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, history of drug-induced liver injury, pregnancy, lactation
๐ Monitoring Parameters
Liver function tests (ALT, AST), renal function, blood pressure
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Gastric lavage, activated charcoal, supportive care; no specific antidote
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for brufit od 400 mg tablet
View AllAlternative brands with exact same active ingredient (Flupirtine (400mg)):
-
fluprisan 400mg tablet srEisai Pharmaceuticals India Pvt Ltd โน144.38 10% COSTLIER
-
snepdol od tablet erSun Pharmaceutical Industries Ltd โน147.00 12% COSTLIER
-
retense od tablet erSun Pharmaceutical Industries Ltd โน178.00 35.6% COSTLIER
-
acronil-od 400 tablet erConsern Pharma Limited โน192.19 46.4% COSTLIER
-
Rypirtin 400mg CapsuleRyon Pharma โน210.00 60% COSTLIER
-
ketoflam sr tabletLupin Ltd โน321.95 145.3% COSTLIER
-
flugesic sr tabletLupin Ltd โน337.30 157% COSTLIER
-
lupirtin -sr tabletLupin Ltd โน371.15 182.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.