acronil-od 400 tablet er - Uses, Price, Side Effects & Substitutes
What is acronil-od 400 tablet er used for?
Acronil (Flupirtine) is used to treat PAIN ANALGESICS. It contains Flupirtine (400mg), which Selective neuronal potassium channel opener; indirect NMDA receptor antagonist. Always consult your doctor before use. Take as prescribed.
- Generic Name: Flupirtine
- Manufacturer: Consern Pharma Limited
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ acronil-od 400 tablet er Uses & Benefits
Acute and chronic pain, muscle spasms
Off-label uses: Neuropathic pain, fibromyalgia
๐ Drug Information
| Generic Name(s) | Flupirtine |
| Brand Name | Acronil |
| Manufacturer | Consern Pharma Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Selective neuronal potassium channel openers (SNEPCO) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Selective neuronal potassium channel opener; indirect NMDA receptor antagonist
Mechanism Steps
๐ก How to Take acronil-od 400 tablet er
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of acronil-od 400 tablet er
โ Common Side Effects
- Dizziness
- Drowsiness
- Nausea
- Constipation
- Dry mouth
๐จ Serious Side Effects
- Hepatotoxicity
- Liver failure
- Seizures
- Allergic reactions
โ ๏ธ Rare Side Effects
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Alcohol | Major | Enhanced sedation and hepatotoxicity |
| CNS depressants | Major | Additive sedation |
| MAO inhibitors | Major | Risk of hypertensive crisis |
| Antihypertensives | Moderate | Enhanced hypotensive effect |
| Diuretics | Moderate | Increased risk of electrolyte imbalance |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Antacids | Minor | Slight decrease in absorption |
| Cimetidine | Minor | Increased flupirtine levels |
๐จ Major Interactions
- Warfarin
- CNS depressants
- MAO inhibitors
โก Moderate Interactions
- Antihypertensives
- Diuretics
- Oral contraceptives
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
High-fat meals may delay absorption
๐ท Alcohol Interaction
Increased CNS depression and hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, history of drug-induced liver injury, pregnancy, lactation
๐ Monitoring Parameters
Liver function tests (ALT, AST), renal function, blood pressure
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Gastric lavage, activated charcoal, supportive care; no specific antidote
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for acronil-od 400 tablet er
View AllAlternative brands with exact same active ingredient (Flupirtine (400mg)):
-
brufit od 400 mg tabletAbbott โน131.25 31.7% CHEAPER
-
snepdol od tablet erSun Pharmaceutical Industries Ltd โน147.00 23.5% CHEAPER
-
fluprisan 400mg tablet srEisai Pharmaceuticals India Pvt Ltd โน154.00 19.9% CHEAPER
-
retense od tablet erSun Pharmaceutical Industries Ltd โน178.00 7.4% CHEAPER
-
Rypirtin 400mg CapsuleRyon Pharma โน224.00 16.6% COSTLIER
-
ketoflam sr tabletLupin Ltd โน270.50 40.7% COSTLIER
-
flugesic sr tabletLupin Ltd โน270.60 40.8% COSTLIER
-
lupirtin -sr tabletLupin Ltd โน297.50 54.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.