bronkese 169.4mg/50.6mg injection
What is bronkese 169.4mg/50.6mg injection used for?
Asmaphylin M 231mg/69mg/10mg Tablet SR (Etofylline + Theophylline) is used to treat RESPIRATORY. It contains Etofylline (169.4mg) + Theophylline (50.6mg), which Inhibits phosphodiesterase, increasing cAMP; antagonizes adenosine receptors; en. Always consult your doctor before use. Take as prescribed.
- Generic Name: Etofylline + Theophylline
- Manufacturer: Tribhawan Injectables
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ bronkese 169.4mg/50.6mg injection Uses & Benefits
Bronchial asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions with bronchospasm.
Off-label uses: Apnea of prematurity, Postoperative respiratory depression
๐ Drug Information
| Generic Name(s) | Etofylline + Theophylline |
| Brand Name | Asmaphylin M 231mg/69mg/10mg Tablet SR |
| Manufacturer | Tribhawan Injectables |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Xanthine bronchodilator |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits phosphodiesterase, increasing cAMP; antagonizes adenosine receptors; enhances mucociliary clearance.
Mechanism Steps
๐ก How to Take bronkese 169.4mg/50.6mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bronkese 169.4mg/50.6mg injection
โ Common Side Effects
- Nausea
- Vomiting
- Headache
- Insomnia
- Nervousness
- Tachycardia
๐จ Serious Side Effects
- Seizures
- Arrhythmias
- Severe hypotension
- Respiratory arrest
โ ๏ธ Rare Side Effects
- Hyperglycemia
- Hypokalemia
- Rhabdomyolysis
- Allergic reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Cimetidine | Major | Decreased theophylline clearance, increased toxicity risk. |
| Ciprofloxacin | Major | Increased theophylline levels, risk of seizures. |
| Erythromycin | Major | Increased theophylline levels, toxicity. |
| Fluvoxamine | Major | Markedly increased theophylline levels. |
| Methotrexate | Major | Increased theophylline levels. |
| Propranolol | Major | Reduced theophylline clearance, antagonism of bronchodilation. |
| Carbamazepine | Moderate | Decreased theophylline levels. |
| Phenytoin | Moderate | Decreased theophylline levels. |
| Rifampin | Moderate | Decreased theophylline levels. |
| Smoking | Moderate | Increased theophylline metabolism, reduced efficacy. |
| St. John's Wort | Moderate | Decreased theophylline levels. |
| Allopurinol | Minor | Slight increase in theophylline levels. |
| Benzodiazepines | Minor | Possible additive CNS depression. |
| Disulfiram | Minor | Decreased theophylline clearance. |
| Interferon | Minor | Decreased theophylline clearance. |
| Verapamil | Minor | Increased theophylline levels. |
๐จ Major Interactions
- Cimetidine
- Ciprofloxacin
- Erythromycin
- Fluvoxamine
- Methotrexate
- Propranolol
โก Moderate Interactions
- Carbamazepine
- Phenytoin
- Rifampin
- Smoking (tobacco/marijuana)
- St. John's Wort
โน๏ธ Minor Interactions
- Allopurinol
- Benzodiazepines
- Disulfiram
- Interferon
- Verapamil
๐ฝ๏ธ Food Interactions
High-fat meals may delay absorption; charcoal-broiled foods increase metabolism; caffeine-containing foods may increase side effects.
๐ท Alcohol Interaction
Alcohol may increase theophylline metabolism and reduce efficacy; also may increase risk of seizures.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to xanthines, active peptic ulcer, seizure disorders (unless controlled), severe cardiac arrhythmias.
๐ Monitoring Parameters
Serum theophylline levels (therapeutic range 10-20 mcg/mL), heart rate, respiratory rate, CNS symptoms.
๐คฑ Lactation Safety
Use with caution; theophylline excreted in breast milk; may cause irritability in infants.
๐ Overdose Management
Activated charcoal, supportive care, monitoring of serum theophylline levels; severe cases may require hemodialysis.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.