Bronkese 169.4mg/50.6mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe chest pain or palpitations
- Seizures or convulsions
- Difficulty breathing or wheezing that worsens
- Swelling of face, lips, or throat
- Severe nausea or vomiting
- Irregular heartbeat
- Loss of consciousness
If experiencing severe symptoms, call emergency services immediately.
What is bronkofylin 169.4mg/50.6mg injection used for?
This medicine is a combination bronchodilator injection containing etofylline and theophylline. It is used to treat bronchospasm in asthma and COPD. It works by relaxing airway muscles. It must be given by a healthcare professional.
- Generic Name: Etofylline + Theophylline
- Manufacturer: Indus Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 bronkofylin 169.4mg/50.6mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा एटोफिलिन और थियोफिलिन का संयोजन है, जिसका उपयोग अस्थमा और सीओपीडी जैसी श्वसन संबंधी समस्याओं में सांस लेने में आसानी के लिए किया जाता है। यह श्वसन मार्ग की मांसपेशियों को आराम देकर ब्रोंकोस्पाज्म को कम करती है। यह इंजेक्शन के रूप में दी जाती है और इसे केवल डॉक्टर या नर्स द्वारा ही लगाया जाना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, सिरदर्द, बेचैनी और नींद न आना शामिल हैं। गंभीर दुष्प्रभावों में दिल की धड़कन तेज होना, दौरे पड़ना और एलर्जी की प्रतिक्रिया शामिल हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं। अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों और दवाओं के बारे में बताएं। इलाज के दौरान शराब और कैफीन से बचें। डॉक्टर की सलाह के बिना कोई भी दवा न लें।
💊 bronkofylin 169.4mg/50.6mg injection Uses & Benefits
[{"condition":"Bronchial asthma","description":"Relieves acute bronchospasm and improves breathing in asthma exacerbations.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Helps reduce airway obstruction and improve symptoms in COPD.","evidence":"Well-established"},{"condition":"Apnea of prematurity","description":"Used as a respiratory stimulant in premature infants, though evidence for this combination is limited.","evidence":"Limited"}]
Off-label uses: [{"condition":"Respiratory depression","description":"Sometimes used to stimulate breathing in conditions causing reduced respiratory drive.","evidence":"Limited"}]
Primary treatment for: Bronchial asthma
Also treats: Chronic obstructive pulmonary disease (COPD), Apnea of prematurity
📋 Drug Information
| Generic Name(s) | Etofylline + Theophylline |
| Brand Name | Asmaphylin M 231mg/69mg/10mg Tablet SR |
| Manufacturer | Indus Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Xanthine bronchodilator |
| Route of Administration | Parenteral (intravenous or intramuscular, as directed by a healthcare professional) |
| Storage | Store in a cool, dry place, protected from light. Do not freeze. Keep out of reach of children. |
| Shelf Life | Not established from the available information. Refer to the product packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting phosphodiesterase enzymes, which leads to increased levels of cyclic AMP and cyclic GMP in bronchial smooth muscle cells. This results in relaxation of the airway muscles and widening of the bronchi. Additionally, it blocks adenosine receptors, which contributes to bronchodilation and reduces airway inflammation. Theophylline also improves diaphragm contractility and stimulates the respiratory center in the brain.
Mechanism Steps
💡 How to Take bronkofylin 169.4mg/50.6mg injection
Strength: Injection: Etofylline 169.4 mg and Theophylline 50.6 mg per dose.
Dosage Information
| Adult Dosage | The dosage is individualized by a qualified clinician based on the patient's condition, age, weight, and renal and hepatic function. It is typically administered by a healthcare professional in a clinical setting. Do not self-administer. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require lower doses due to reduced clearance. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be necessary in patients with renal impairment. Consult a qualified clinician. |
| Hepatic Impairment | Dose adjustment may be necessary in patients with hepatic impairment. Consult a qualified clinician. |
| Maximum Daily Dose | Not established from the available information. The maximum dose must be determined by a qualified clinician. |
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of bronkofylin 169.4mg/50.6mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ciprofloxacin | Major | |
| Erythromycin | Major | |
| Propranolol | Major | |
| Phenytoin | Moderate | |
| Cimetidine | Moderate | |
| Caffeine | Minor |
🚨 Major Interactions
- Ciprofloxacin
- Erythromycin
- Propranolol
⚡ Moderate Interactions
- Phenytoin
- Cimetidine
🍷 Alcohol Interaction
Alcohol may increase the risk of side effects such as nausea, dizziness, and rapid heartbeat. It is advisable to avoid alcohol while receiving this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to etofylline, theophylline, or other methylxanthines","Severe cardiac arrhythmias","Severe liver disease","Uncontrolled seizure disorders","Acute porphyria"]
⚠️ Warnings & Precautions
["Use with caution in patients with heart disease, hypertension, or hyperthyroidism.","May impair ability to drive or operate machinery.","Avoid in patients with peptic ulcer disease.","Use with caution in the elderly and in patients with renal or hepatic impairment.","Do not administer concurrently with other xanthine derivatives."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before use if breastfeeding.
💊 Overdose Management
Overdose can cause severe nausea, vomiting, restlessness, tachycardia, arrhythmias, and seizures. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion was recent. Monitor vital signs and electrolytes.
⏰ Missed Dose
This medicine is administered by a healthcare professional. If you miss a scheduled dose, contact your doctor or nurse as soon as possible. Do not attempt to self-administer a double dose.
Additional Safety Advice
This medicine should only be administered by a qualified healthcare professional. Do not attempt to self-administer. Inform your doctor about all your medical conditions, especially heart, liver, or kidney problems, and any medications you are taking. Avoid alcohol and caffeine during treatment as they can increase side effects. Your doctor may monitor your heart rate, blood pressure, and blood levels of the medicine. Do not drive or operate machinery immediately after receiving this injection. Keep all follow-up appointments.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially cardiac and central nervous system effects. Lower doses may be required, and close monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before receiving this medicine. The safety profile in pregnancy is not well established.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you have received this medicine recently, as it can interact with other medications used during surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with epinephrine used in local anesthetics, potentially causing heart rhythm changes.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise immediately after receiving this injection. Consult your doctor before starting any exercise program, especially if you have heart or lung conditions.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, restlessness, or palpitations, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Discuss with your doctor about when you can resume normal activities.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. It is given under medical supervision, and the decision to stop will be made by your healthcare provider based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine is not typical as it is usually given for acute situations. Prolonged use may lead to tolerance and increased risk of side effects. Regular monitoring of heart, liver, and kidney function is advised if used long-term.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Inhaled medications like albuterol are often preferred for acute bronchospasm due to fewer systemic side effects.
Evidence: Well-establishedUsed to reduce airway inflammation in asthma and COPD.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Ensure you are up to date with influenza and pneumococcal vaccinations, as respiratory infections can worsen asthma and COPD.
📦 Storage Guide
✅ DO
Store in a cool, dry place
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
This medicine is administered by healthcare professionals and is not for self-administration. If you are traveling and need this medicine, ensure you have a prescription and a letter from your doctor. Carry it in its original packaging. Check with airlines and customs about carrying injectable medications. Store according to the label instructions.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of action varies, but it typically works within minutes when given intravenously. Your doctor will monitor your response.
A: Consult your doctor. The safety in pregnancy is not well established, and it should only be used if clearly needed.
A: Avoid alcohol, caffeine, and driving or operating machinery until you know how it affects you.
🤔 Common Patient Concerns
🔄 Substitutes for bronkofylin 169.4mg/50.6mg injection
View AllAlternative brands with exact same active ingredient:
-
dericip 169.4mg/50.6mg injectionCipla Ltd ₹2.25 34.8% CHEAPER
-
bronkese 169.4mg/50.6mg injectionTribhawan Injectables ₹3.34 3.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be self-administered at home.
Fact: This medicine must be given by a healthcare professional in a clinical setting. - Myth: It is safe to take with any other medication.
Fact: It can interact with many drugs, so always inform your doctor about all medicines you take.