dericip 169.4mg/50.6mg injection - Etofylline (169.4mg) + Theophylline (50.6mg) medicine

Dericip 169.4mg/50.6mg Injection: Complete Medicine Guide

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🏭 Cipla Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Established for methylxanthine class in reversible airway obstruction.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Irregular or very fast heartbeat
  • Seizures or loss of consciousness
  • Severe dizziness or fainting
  • Swelling of the face, lips, or throat
  • Difficulty breathing that gets worse
  • Severe nausea and vomiting that does not stop
  • Chest pain or tightness

If experiencing severe symptoms, call emergency services immediately.

What is dericip 169.4mg/50.6mg injection used for?

This medicine is a prescription injection that combines etofylline and theophylline to open up the airways in conditions such as asthma and chronic obstructive pulmonary disease. It is given by a healthcare professional in a hospital or clinic and is not for home use.

  • Generic Name: Etofylline (169.4mg) + Theophylline (50.6mg)
  • Manufacturer: Cipla Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dericip 169.4mg/50.6mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा एटोफिलिन और थियोफिलिन का संयोजन है और इसे इंजेक्शन के रूप में दिया जाता है। यह अस्थमा और क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिजीज जैसी स्थितियों में श्वास नलियों को फैलाकर सांस लेना आसान बनाती है। यह दवा केवल अस्पताल या क्लिनिक में प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही दी जाती है। इसे घर पर स्वयं नहीं लगाया जाना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, सिरदर्द, बेचैनी, नींद न आना और दिल की धड़कन तेज होना शामिल हैं। कभी-कभी दिल की धड़कन अनियमित हो सकती है, दौरे पड़ सकते हैं या रक्तचाप बहुत कम हो सकता है। ऐसा होने पर तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल डॉक्टर की देखरेख में अस्पताल या क्लिनिक में ही दी जानी चाहिए। इसका इंजेक्शन स्वयं न लगाएं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर दिल, संक्रमण और अस्थमा की दवाओं के बारे में। इलाज के दौरान शराब और ज्यादा चाय-कॉफी से बचें। गर्भावस्था या स्तनपान के दौरान डॉक्टर को जरूर बताएं।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 dericip 169.4mg/50.6mg injection Uses & Benefits

[{"condition":"Acute bronchospasm in asthma","description":"This medicine is used to relieve sudden narrowing of the airways during an asthma attack when a rapid bronchodilator effect is required.","evidence":"Established for methylxanthine class"},{"condition":"Acute exacerbation of chronic obstructive pulmonary disease","description":"It helps to open the airways and ease breathlessness in patients with chronic obstructive pulmonary disease who cannot take oral bronchodilators.","evidence":"Established for methylxanthine class"},{"condition":"Reversible airway obstruction","description":"This product is used in supervised settings to reverse bronchoconstriction caused by various respiratory conditions.","evidence":"Established for methylxanthine class"},{"condition":"Neonatal apnoea of prematurity","description":"Methylxanthines such as theophylline are used in specialist neonatal units to reduce episodes of apnoea in premature infants.","evidence":"Established for theophylline in neonatal care"}]

Off-label uses: [{"condition":"Severe breathlessness in advanced lung disease","description":"Occasionally used in palliative settings to ease distressing breathlessness, but this is not a standard approved indication.","evidence":"Limited"}]

Primary treatment for: Reversible airway obstruction

Also treats: Asthma, Chronic obstructive pulmonary disease, Neonatal apnoea of prematurity

📋 Drug Information

Generic Name(s)Etofylline (169.4mg) + Theophylline (50.6mg)
Brand Namedericip 169.4mg/50.6mg injection
ManufacturerCipla Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationParenteral
StorageStore this medicine in its original packaging at room temperature, away from direct sunlight and moisture. Do not freeze unless the manufacturer's instructions specifically allow it. Keep it out of the reach of children.
Shelf LifeThe shelf life is not established from the available information. Always check the expiry date printed on the pack before use.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always administer this medicine slowly and under continuous heart rate and blood pressure monitoring.
2
Check for other methylxanthine medicines before giving this injection to avoid accidental overdose.
3
Review the patient's medicines for ciprofloxacin, erythromycin, or cimetidine, as these can raise drug levels.
4
Use a lower dose in elderly patients and those with liver or kidney disease.
5
Watch closely for nausea, vomiting, tremor, or palpitations, as these may be early signs of toxicity.
6
Avoid combining this medicine with non-selective beta blockers such as propranolol.
7
Document the dose, route, and time of administration clearly in the patient's record.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Wheezing and shortness of breath
This medicine is commonly used in supervised settings for reversible airway obstruction.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Chest tightness
It may be used when chest tightness is due to narrowed airways.
Likely Use
❌
Sneezing and runny nose
This medicine is not used for allergic rhinitis.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is given as an injection, so it does not need to be absorbed from the stomach or intestines. It enters the bloodstream directly and rapidly after administration.
DistributionAfter injection, etofylline and theophylline distribute throughout body fluids and tissues. Theophylline crosses the placenta and is also found in breast milk. Protein binding of theophylline is approximately 40 percent in adults, but this can be lower in newborns and in people with liver disease.
Protein BindingTheophylline is about 40 percent bound to plasma proteins in adults. Etofylline binding data are not established from the available information.
MetabolismTheophylline is metabolized mainly in the liver by cytochrome P450 enzymes, including CYP1A2 and CYP3A4. Etofylline is also metabolized in the liver, partly by conversion to theophylline. Liver disease, fever, and certain medicines can slow this metabolism and raise drug levels in the body.
Half-LifeThe elimination half-life of theophylline is usually about 3 to 8 hours in healthy adults, but it can be longer in newborns, the elderly, and people with liver disease or heart failure. Etofylline half-life data are not established from the available information.
ExcretionTheophylline and its metabolites are excreted mainly through the kidneys in the urine. A small amount is excreted unchanged. Kidney impairment can prolong the elimination of the drug and its metabolites.
BioavailabilityBioavailability is not applicable in the usual sense because this medicine is given by injection and enters the bloodstream directly. The full dose is available to the body after intravenous administration.
Onset of ActionWhen given intravenously, this medicine begins to act within minutes. The exact onset depends on how quickly the injection is administered and the patient's condition.
Peak Plasma TimePeak plasma levels occur at the end of an intravenous injection or shortly after an intramuscular injection. The exact time is not established from the available information for this specific combination product.
Duration of ActionThe bronchodilator effect usually lasts several hours, depending on the dose and the patient's metabolism. The exact duration for this specific combination product is not established from the available information.

How It Works

Etofylline and theophylline are methylxanthine derivatives that relax bronchial smooth muscle and widen the airways. They work mainly by inhibiting phosphodiesterase enzymes, which raises cyclic AMP inside smooth muscle cells and leads to relaxation. Theophylline also blocks adenosine receptors, which contributes to bronchodilation and to some of the stimulant effects on the heart and nervous system. In addition, these agents improve the strength and efficiency of the diaphragm, stimulate the respiratory centre in the brain, and help clear mucus from the airways.

Mechanism Steps

1
Phosphodiesterase inhibition: This medicine inhibits phosphodiesterase enzymes in bronchial smooth muscle, which prevents the breakdown of cyclic AMP.
2
Rise in cyclic AMP: Higher cyclic AMP levels reduce calcium availability inside smooth muscle cells, causing the muscle to relax.
3
Adenosine receptor blockade: Theophylline blocks adenosine receptors on the surface of airway and cardiac cells, which adds to bronchodilation and stimulates the heart.
4
Airway opening: Relaxation of bronchial smooth muscle widens the airways and makes it easier for air to move in and out of the lungs.
5
Improved breathing mechanics: The medicine strengthens diaphragm contraction and stimulates the respiratory centre, which further improves ventilation.

💡 How to Take dericip 169.4mg/50.6mg injection

Strength: Injection containing etofylline 169.4 mg and theophylline 50.6 mg.

1This medicine is given only by a trained healthcare professional in a hospital or clinic.
2The injection is administered slowly into a vein or muscle as decided by the doctor.
3Your heart rate, blood pressure, and breathing will be monitored during and after the injection.
4Tell the doctor or nurse immediately if you feel dizzy, nauseated, or have a racing heartbeat.
5Do not attempt to self-administer this medicine at home under any circumstances.

Dosage Information

Adult DosageThe dose of this medicine is determined by the treating doctor based on the patient's condition, weight, age, and kidney and liver function. It is given by a healthcare professional as an intravenous or intramuscular injection, and the rate of administration is controlled to reduce the risk of side effects. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not attempt to calculate or self-administer this medicine at home.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageOlder adults may need a lower dose because the body clears this medicine more slowly with age. The doctor will adjust the dose based on kidney and liver function, body weight, and other medicines being taken.
Renal ImpairmentPeople with kidney impairment may need a reduced dose or longer intervals between doses because the drug and its metabolites are removed more slowly. The doctor will decide the exact dose after assessing kidney function.
Hepatic ImpairmentPeople with liver disease may need a reduced dose because theophylline is broken down in the liver. The doctor will monitor for side effects and adjust the dose as needed.
Maximum Daily DoseThe maximum daily dose is not established from the available information for this specific combination product. The dose must be individualized by a qualified clinician based on the patient's condition and response.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Caffeine-containing drinks
Limit or avoid
Caffeine can increase restlessness, palpitations, and insomnia when combined with this medicine.
Regular meals
No specific restriction
This medicine is given by injection, so food timing does not directly affect its absorption.

⏰ What to Do If You Miss a Dose

📌 A scheduled dose is missed in the hospital
→ Inform the nursing staff immediately.
💡 The medical team will decide whether to give the dose late or skip it based on your treatment plan.
📌 You are unsure whether a dose was given
→ Ask your nurse or doctor to check your medication record.
💡 Do not ask for an extra dose without medical advice.

⚠️ Side Effects of dericip 169.4mg/50.6mg injection

✅ Common Side Effects

Nausea (Common)
Inform the nurse or doctor. The injection may need to be given more slowly.
Vomiting (Common)
Report to the treating team. They may adjust the dose or rate of administration.
Headache (Common)
Rest and inform the doctor if the headache is severe or persistent.
Restlessness or insomnia (Common)
Tell the doctor if this becomes troublesome. Avoid caffeine during treatment.
Fast heartbeat (Common)
The doctor will monitor your heart rate. Report palpitations or chest discomfort immediately.
Stomach discomfort (Common)
Inform the nursing staff so they can assess whether the dose needs adjustment.

🚨 Serious Side Effects

Irregular heart rhythm (Uncommon)
Seek immediate medical attention if you feel a racing, fluttering, or irregular heartbeat.
Seizures (Rare)
This is a medical emergency. Call for emergency help immediately.
Severe low blood pressure (Rare)
Seek immediate medical attention if you feel dizzy, faint, or very weak.
Severe allergic reaction (Rare)
Seek emergency care if you develop swelling of the face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Skin rash
Report to the doctor. The medicine may need to be stopped.
Low potassium levels
The doctor may check your blood potassium level and correct it if needed.
High blood sugar
Blood sugar may be monitored, especially in people with diabetes.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ciprofloxacin Major
Erythromycin Major
Cimetidine Major
Propranolol Major
Phenytoin Moderate
Rifampicin Moderate
Oral contraceptives Moderate
Furosemide Moderate
Caffeine Minor
St John's wort Minor

🚨 Major Interactions

  • Ciprofloxacin
  • Erythromycin and other macrolide antibiotics
  • Cimetidine
  • Propranolol and other non-selective beta blockers

⚡ Moderate Interactions

  • Phenytoin
  • Rifampicin
  • Oral contraceptives
  • Furosemide

🍷 Alcohol Interaction

Alcohol should be avoided while receiving this medicine. Alcohol can increase drowsiness, affect heart rate, and make it harder to judge the medicine's side effects. It may also worsen stomach irritation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to etofylline, theophylline, or other methylxanthines","Serious heart rhythm disturbances such as severe tachyarrhythmias","Active peptic ulcer disease","Uncontrolled seizure disorder","Acute porphyria"]

⚠️ Warnings & Precautions

["This medicine must only be given by a qualified healthcare professional.","Use with caution in people with heart disease, high blood pressure, or irregular heart rhythms.","Use with caution in people with liver disease, kidney disease, or thyroid disorders.","The dose may need to be reduced in the elderly and in people with low body weight.","Avoid giving this medicine together with other methylxanthines to prevent overdose.","Monitor for signs of theophylline toxicity such as nausea, vomiting, tremor, and palpitations.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Theophylline passes into breast milk and may cause irritability or poor sleep in a breastfed baby. Breastfeeding while receiving this medicine should only be done after discussing the risks and benefits with a doctor.

💊 Overdose Management

Overdose of this medicine can cause severe nausea, vomiting, restlessness, fast or irregular heartbeat, seizures, and a dangerous drop in blood pressure. If overdose is suspected, stop the medicine immediately and seek emergency medical care. Treatment is supportive and may include monitoring of heart rhythm, blood pressure, and breathing, along with measures to remove the drug from the body if advised by a specialist. There is no specific antidote, so management focuses on controlling symptoms and supporting vital functions.

⏰ Missed Dose

This medicine is given by a healthcare professional in a hospital or clinic, so a missed dose is unlikely to happen at home. If a scheduled dose is missed in a healthcare setting, the medical team will decide whether to give it late or skip it based on the treatment plan. Never try to make up for a missed dose by taking extra medicine on your own.

Additional Safety Advice

General Safety

This medicine must only be given by a trained healthcare professional in a setting where heart rhythm, blood pressure, and breathing can be monitored. Never attempt to self-administer this injection. Tell your doctor about all other medicines you take, especially those for heart problems, antibiotics, and asthma, because many drugs can raise or lower the levels of this medicine in your body. Avoid alcohol and large amounts of caffeine-containing drinks such as strong coffee, tea, and energy drinks while receiving this medicine, as they can increase the risk of palpitations and restlessness. If you are pregnant, planning pregnancy, or breastfeeding, inform your doctor before this medicine is given. Keep all follow-up appointments so that your doctor can check how well the medicine is working and adjust the dose if needed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Older adults may clear this medicine more slowly and are more likely to have heart or kidney problems. They may need a lower dose and closer monitoring for side effects such as palpitations, dizziness, and confusion.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, discuss this medicine with your doctor before conception. Methylxanthines cross the placenta, and the decision to use this medicine during pregnancy should be based on a careful assessment of benefits and risks.

🏥 Post-Surgery Considerations

After surgery, this medicine may be used if you develop breathing difficulty due to narrowed airways. The surgical and anesthesia teams should be informed about all medicines you are receiving so that interactions and side effects can be managed safely.

🦷 Dental Procedures

Inform your dentist if you have received this medicine, especially if you have a history of heart rhythm problems. Your dentist may need to take extra precautions during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke, as these can worsen breathing problems.
🥗
Keep your home free from dust, strong perfumes, and other triggers that irritate the airways.
😴
Follow your doctor's advice on using inhalers and other long-term controller medicines.
💧
Stay up to date with your vaccinations, including flu and pneumonia vaccines, as advised by your doctor.
🧘
Practice breathing exercises recommended by your healthcare team.
🌞
Maintain a healthy weight and eat a balanced diet to support lung health.

🏋️ Exercise Considerations

Avoid strenuous exercise during an acute episode of breathlessness. Once your condition is stable, gentle activity such as walking or breathing exercises may help. Always follow your doctor's advice about how much activity is safe for you.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit caffeine-containing drinks such as strong coffee, tea, and energy drinks.
Stay well hydrated unless your doctor has advised fluid restriction.
Avoid very heavy meals if they make you feel breathless.

💼 Impact on Daily Work & Life

This medicine is given in a hospital or clinic, and you may feel drowsy, dizzy, or have a fast heartbeat afterward. Do not drive or operate heavy machinery until you feel fully alert and your doctor says it is safe. Depending on your condition, you may need time off work to recover.

🛑 When to Stop This Medicine

This medicine is stopped by the treating doctor once your breathing improves or when the course is complete. Do not stop or change the treatment on your own. If you develop severe side effects such as irregular heartbeat, seizures, or severe dizziness, the doctor will stop the medicine immediately and manage the reaction.

📅 Long-Term Use Effects

Long-term use of methylxanthine medicines can lead to tolerance, sleep problems, and an increased risk of heart rhythm disturbances. Regular monitoring of heart rate, blood pressure, and drug levels may be needed. If you are on long-term treatment, your doctor will review your dose and may adjust it based on your response and any side effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled bronchodilators

Inhaled medicines such as salbutamol are often preferred for quick relief of airway narrowing and are easier to use outside the hospital.

Evidence: Well-established
Inhaled corticosteroids

These are used for long-term control of asthma and reduce the frequency of attacks.

Evidence: Well-established
Oxygen therapy

Oxygen may be given along with bronchodilators in severe breathing difficulty.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

People with chronic lung diseases such as asthma and COPD should stay up to date with influenza and pneumococcal vaccinations as advised by their doctor. There is no known direct interaction between this medicine and vaccines, but vaccination should be planned when you are medically stable.

📦 Storage Guide

✅ DO

Store at room temperature in the original packaging.

❌ DON'T

Do not freeze unless the manufacturer's instructions allow it.

✅ DO

Keep away from direct sunlight and moisture.

❌ DON'T

Do not store in a bathroom cabinet.

✅ DO

Check the expiry date before use.

❌ DON'T

Do not use if the solution is discolored or contains particles.

✅ DO

Keep out of the reach of children.

❌ DON'T

Do not transfer to unmarked containers.

✈️ Traveling with This Medicine

This medicine is given in a hospital or clinic, so travel planning usually applies to the overall treatment plan rather than carrying the injection yourself. If you need to travel while receiving treatment, carry a copy of your prescription and a letter from your doctor explaining your condition and medicines. Keep medicines in their original packaging and store them at room temperature, away from direct sunlight. If you are crossing time zones, ask your doctor whether your treatment schedule needs adjustment. Always check the customs rules of your destination for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man with chronic obstructive pulmonary disease admitted with severe breathlessness
He received this medicine as a slow injection under close monitoring in the hospital. His breathing improved within a short time, and the nursing team watched his heart rate and blood pressure throughout. He was later switched to an inhaler-based treatment plan for long-term control.
💡 Lesson: This medicine can provide rapid relief in a supervised setting, but it is not a substitute for a long-term treatment plan.
👤 A 34-year-old woman with an acute asthma attack who could not take oral medicines
Because she was vomiting and could not keep oral medicines down, the doctor gave this injection in the emergency department. Her wheezing improved, and she was observed for side effects such as nausea and palpitations. She was advised to avoid caffeine during her hospital stay.
💡 Lesson: Injection forms are useful when oral therapy is not possible, but they must always be given by a healthcare professional.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: When given intravenously, this medicine starts working within minutes. The exact speed depends on how it is administered and your condition.

Q: Can I take this medicine at home?

A: No. This medicine must only be given by a trained healthcare professional in a hospital or clinic with proper monitoring.

Q: What are the common side effects?

A: Common side effects include nausea, vomiting, headache, restlessness, and a fast heartbeat. Tell your doctor or nurse if these occur.

Q: Is this medicine safe during pregnancy?

A: Methylxanthines cross the placenta. Use during pregnancy should only be considered after a careful discussion of benefits and risks with your doctor.

Q: Can I drink alcohol while receiving this medicine?

A: It is best to avoid alcohol during treatment, as it can increase drowsiness and affect your heart rate.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can this medicine be given at home?
  • How often will my heart rate be checked?
  • Will this medicine interact with my heart medicines?
  • Is this medicine safe in pregnancy?
  • What should I do if I feel palpitations during the injection?
  • Can I drink coffee while receiving this medicine?

🔄 Substitutes for dericip 169.4mg/50.6mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be self-injected at home like insulin.
    Fact: This medicine must only be given by a trained healthcare professional in a monitored setting.
  • Myth: This medicine is a cure for asthma.
    Fact: This medicine relieves airway narrowing but does not cure the underlying condition. Long-term control needs a proper treatment plan.
  • Myth: More of this medicine will always work better.
    Fact: Higher doses can cause serious heart rhythm problems and seizures. The dose must be carefully individualized.

🔄 Alternative Options

Generic Alternatives

  • Etofylline and theophylline injection
  • Theophylline injection
  • Etofylline injection

Brand Alternatives

  • Dericip 169.4mg/50.6mg injection

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Etofylline 169.4 mg + Theophylline 50.6 mg","route":"Parenteral","main_use":"Reversible airway obstruction"},{"medicine":"Aminophylline injection","composition":"Aminophylline","route":"Parenteral","main_use":"Reversible airway obstruction"},{"medicine":"Theophylline injection","composition":"Theophylline","route":"Parenteral","main_use":"Reversible airway obstruction"}]

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