bisonate 1000mg tablet - Sodium Bicarbonate (1000mg) medicine

Auxisoda-DS Tablet: Complete Medicine Guide

No reviews yet
🏭 Cmg Biotech Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for acid indigestion and urinary alkalinization.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Irregular or rapid heartbeat
  • Severe stomach pain or vomiting blood
  • Confusion, muscle twitching, or seizures
  • Decreased urine output or swelling in legs
  • Severe allergic rash or itching
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is bisonate 1000mg tablet used for?

This medicine is an oral tablet containing Sodium Bicarbonate 1000 mg. It is used to relieve acid indigestion, heartburn, and to alkalinize urine. It works by neutralizing stomach acid and raising blood and urine pH. It should be taken as directed by a doctor and is not for long-term self-medication.

  • Generic Name: Sodium Bicarbonate
  • Manufacturer: Cmg Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 bisonate 1000mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सोडियम बाइकार्बोनेट 1000 मिलीग्राम की एक ओरल टैबलेट है। इसका उपयोग एसिडिटी, सीने में जलन, और पेट की गैस से राहत पाने के लिए किया जाता है। यह पेट के एसिड को बेअसर करके और यूरिन को क्षारीय बनाकर काम करती है। कुछ मामलों में यह गुर्दे की पथरी को रोकने और मेटाबॉलिक एसिडोसिस के इलाज में भी मदद करती है। इसका सेवन डॉक्टर की सलाह के अनुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट में गैस, डकार, जी मिचलाना और पेट फूलना शामिल हैं। कभी-कभी प्यास लगना, बार-बार पेशाब आना और हाथ-पैरों में सूजन हो सकती है। गंभीर दुष्प्रभावों में मेटाबॉलिक एल्कलोसिस, सोडियम का बढ़ना, पोटैशियम की कमी, और किडनी की समस्या शामिल हैं। अगर आपको सांस लेने में तकलीफ, दिल की धड़कन अनियमित, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा न बढ़ाएं और न ही लंबे समय तक लें। इसे एक गिलास पानी के साथ लें। अन्य दवाओं के साथ लेने से पहले 1-2 घंटे का अंतराल रखें। अगर आपको हाई ब्लड प्रेशर, दिल की बीमारी, किडनी की समस्या है या आप नमक कम खाते हैं, तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 bisonate 1000mg tablet Uses & Benefits

[{"condition":"Acid indigestion and heartburn","description":"This medicine neutralizes excess stomach acid, providing rapid relief from heartburn, sour stomach, and indigestion.","evidence":"Well-established"},{"condition":"Metabolic acidosis","description":"Used to correct metabolic acidosis by increasing blood bicarbonate levels and restoring normal pH.","evidence":"Well-established"},{"condition":"Urinary alkalinization","description":"Helps make urine less acidic, which is useful in preventing certain kidney stones and improving the effectiveness of some medicines.","evidence":"Well-established"},{"condition":"Uric acid kidney stones","description":"Alkalinizing urine helps dissolve and prevent uric acid stones.","evidence":"Well-established"},{"condition":"Cystine kidney stones","description":"May be used to increase urine pH and reduce cystine stone formation.","evidence":"Moderate"},{"condition":"Drug overdose with acidic drugs","description":"In specific cases, urinary alkalinization is used to enhance elimination of certain acidic drugs like salicylates.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Mouth ulcers","description":"Sometimes used as a mouth rinse to neutralize acid and soothe ulcers, though evidence is limited.","evidence":"Limited"},{"condition":"Dandruff","description":"Occasionally used topically as a rinse, but not a standard medical treatment.","evidence":"Limited"}]

Primary treatment for: Acid indigestion and heartburn

Also treats: Metabolic acidosis, Uric acid kidney stones, Cystine kidney stones

📋 Drug Information

Generic Name(s)Sodium Bicarbonate
Brand NameAcidose 500mg Tablet
ManufacturerCmg Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntacids
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a full glass of water to help it dissolve and reduce stomach irritation.
2
Do not take this medicine within 1-2 hours of other medicines, as it can affect their absorption.
3
Limit use to short-term unless your doctor has prescribed it for a chronic condition.
4
If you have high blood pressure or heart failure, inform your doctor before taking this medicine due to its sodium content.
5
Monitor for signs of electrolyte imbalance such as muscle cramps, weakness, or irregular heartbeat.
6
Do not use this medicine to treat yourself for more than 2 weeks without medical advice.
7
Keep a record of your doses and any side effects to discuss with your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Heartburn
This medicine is commonly used for rapid relief.
Likely Use
Sour stomach
Neutralizes excess acid.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Headache
Not indicated for headache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSodium bicarbonate is rapidly absorbed from the gastrointestinal tract after oral administration. The absorption is efficient, and the bicarbonate ions enter the bloodstream where they contribute to the body's bicarbonate buffer system.
DistributionBicarbonate is distributed throughout the extracellular fluid and is a normal constituent of the body's buffer systems. It does not bind to plasma proteins and is present in all body fluids.
Protein BindingNot established from the available information.
MetabolismSodium bicarbonate is not metabolized in the conventional sense. It participates in acid-base reactions, primarily combining with hydrogen ions to form carbon dioxide and water, which are then eliminated.
Half-LifeNot established from the available information.
ExcretionThe bicarbonate ions are primarily excreted by the kidneys. The kidneys regulate bicarbonate levels by reabsorbing or excreting it as needed to maintain acid-base balance. Some bicarbonate is also lost in feces and sweat.
BioavailabilityNot established from the available information.
Onset of ActionThe onset of action for relief of heartburn is rapid, typically within a few minutes after oral administration. For systemic effects such as urinary alkalinization, the onset may take 30 minutes to 1 hour.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe duration of action for gastric acid neutralization is relatively short, usually less than 30 minutes. For systemic alkalinization, the effect can last for several hours depending on renal function and dose.

How It Works

This medicine works by directly neutralizing excess acid in the stomach and by being absorbed into the bloodstream where it acts as a buffer to raise blood pH. The bicarbonate ion (HCO3-) combines with hydrogen ions (H+) to form carbon dioxide and water, thereby reducing acidity. In the kidneys, it increases the excretion of bicarbonate and raises urine pH, which helps in conditions like uric acid stones and certain drug toxicities.

Mechanism Steps

1
Gastric acid neutralization: Sodium bicarbonate reacts with hydrochloric acid in the stomach to produce sodium chloride, water, and carbon dioxide, which reduces stomach acidity and relieves heartburn.
2
Systemic absorption: A portion of sodium bicarbonate is absorbed into the bloodstream from the gastrointestinal tract.
3
Blood buffering: In the blood, bicarbonate acts as a buffer, combining with excess hydrogen ions to raise blood pH toward normal.
4
Renal effects: The kidneys filter bicarbonate and adjust its reabsorption and excretion, leading to alkalinization of urine.
5
Urinary pH increase: Increased urine pH helps dissolve uric acid and cystine stones and enhances elimination of certain acidic drugs.

💡 How to Take bisonate 1000mg tablet

Strength: Sodium Bicarbonate 1000 mg immediate-release tablet.

1Take this medicine orally with a full glass of water.
2Swallow the tablet whole; do not crush or chew unless directed.
3Take with or after meals to reduce stomach upset.
4Do not take within 1-2 hours of other medicines.
5Follow the dosage schedule prescribed by your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 1000 mg (one tablet) taken orally as needed for acid indigestion, or as directed by a physician for other conditions. For urinary alkalinization, the dose may be repeated every 4 to 6 hours, but the maximum daily dose should not exceed 4 tablets (4000 mg) in 24 hours unless specifically instructed by a doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate for more than 2 weeks.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of sodium bicarbonate, especially regarding fluid retention and electrolyte imbalances. Use with caution and lower doses may be appropriate. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with renal impairment, sodium bicarbonate may accumulate and cause alkalosis. Dose adjustment is required based on renal function. Consult a nephrologist or clinician for individualized dosing.
Hepatic ImpairmentNo specific dosage adjustment is established for hepatic impairment, but use with caution and monitor electrolytes.
Maximum Daily DoseThe maximum daily dose is generally 4000 mg (4 tablets) in 24 hours for adults, but this may vary based on indication and medical advice. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with food
Reduces stomach upset and improves tolerance.
Milk
Avoid taking together
May increase risk of milk-alkali syndrome.
High-sodium foods
Limit
This medicine contains sodium; excess may raise blood pressure.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of bisonate 1000mg tablet

✅ Common Side Effects

Belching (Common (5-10%))
Usually harmless and resolves on its own. Take with water to reduce.
Bloating (Common (5-10%))
May decrease with continued use. Avoid carbonated drinks.
Nausea (Common (5-10%))
Take with food or a full glass of water. Consult doctor if persistent.
Increased thirst (Uncommon (1-5%))
Drink plenty of water. If excessive, consult doctor.
Frequent urination (Uncommon (1-5%))
Usually temporary. Report if accompanied by pain or blood.

🚨 Serious Side Effects

Metabolic alkalosis (Rare (<0.1%))
Seek immediate medical attention if you experience confusion, muscle twitching, or irregular heartbeat.
Hypernatremia (Rare (<0.1%))
Report swelling, rapid weight gain, or shortness of breath to your doctor immediately.
Hypokalemia (Rare (<0.1%))
Consult doctor if you have muscle weakness, cramps, or palpitations.
Kidney stones (Rare (<0.1%))
Seek medical advice if you have severe flank pain or blood in urine.
Severe allergic reaction (Rare (<0.1%))
Call emergency services if you have difficulty breathing, swelling of face or throat, or severe rash.

⚠️ Rare Side Effects

Kidney injury
Report decreased urine output or swelling to your doctor.
Seizures due to severe alkalosis
Seek immediate medical help.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate
Lithium Major
Aspirin Moderate
Tetracycline Moderate
Ketoconazole Moderate
Furosemide Major
Hydrochlorothiazide Major
Corticosteroids Major
Iron supplements Moderate
Amphetamines Minor

🚨 Major Interactions

  • Antacids containing calcium or magnesium
  • Diuretics (e.g., furosemide, hydrochlorothiazide)
  • Corticosteroids
  • Lithium

⚡ Moderate Interactions

  • Aspirin
  • Tetracycline antibiotics
  • Iron supplements
  • Ketoconazole

🍷 Alcohol Interaction

Alcohol may increase stomach irritation and worsen acid-related symptoms. It is advisable to avoid alcohol while taking this medicine, especially if you have a history of ulcers or gastritis.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe kidney disease","Metabolic alkalosis","Hypocalcemia","Hypernatremia","Severe heart failure","Uncontrolled hypertension","Known hypersensitivity to sodium bicarbonate"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart failure, hypertension, or edema.","Avoid long-term use without medical supervision.","May cause sodium overload; monitor in patients on low-sodium diet.","Can alter absorption of other medicines; separate doses.","Not recommended for children without medical advice.","Use with caution in the elderly due to increased risk of electrolyte imbalances.","Do not use if the solution is discolored or contains particles."]

🤱 Lactation Safety

Sodium bicarbonate is excreted in breast milk in small amounts. It is generally considered safe for short-term use during breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose can cause severe metabolic alkalosis, hypernatremia, and hypokalemia. Symptoms include nausea, vomiting, confusion, muscle twitching, and irregular heartbeat. Treatment is supportive and symptomatic, with correction of electrolyte imbalances and acid-base status. Seek immediate medical attention.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it for longer than recommended without medical advice. Take this medicine with a full glass of water to help it dissolve and reduce stomach irritation. Avoid taking it with other medicines within one to two hours, as it can change how they are absorbed. If you have high blood pressure, heart disease, kidney problems, or are on a low-sodium diet, inform your doctor before using this medicine. Do not use this medicine to treat yourself for indigestion for more than two weeks without consulting a doctor. Keep out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Do not take antacids containing calcium or magnesium at the same time without medical advice. Regular monitoring of blood electrolytes and kidney function may be needed during long-term use. Stop the medicine and seek immediate medical help if you notice signs of allergic reaction, severe stomach pain, or irregular heartbeat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to electrolyte imbalances and fluid retention. Use with caution and monitor renal function and electrolytes regularly.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is generally considered safe for short-term use, but medical advice is recommended.

🏥 Post-Surgery Considerations

After surgery, use only if prescribed by your surgeon. It may affect acid-base balance and interact with other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may affect the pH of your mouth and interact with local anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce acid reflux.
🥗
Avoid spicy, fatty, and acidic foods that trigger heartburn.
😴
Eat smaller, more frequent meals.
💧
Do not lie down immediately after eating.
🧘
Elevate the head of your bed if you have nighttime reflux.
🌞
Quit smoking and limit alcohol.
🚭
Stay hydrated by drinking plenty of water.

🏋️ Exercise Considerations

Moderate exercise is generally safe. However, if you experience dizziness or muscle weakness due to electrolyte imbalance, avoid strenuous activity and consult your doctor.

🥗 Diet Recommendations

Include fiber-rich foods like fruits and vegetables.
Reduce intake of processed and high-sodium foods.
Avoid caffeine and carbonated drinks.
Eat yogurt or probiotics to support gut health.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or confusion due to electrolyte imbalance, avoid these activities and consult your doctor.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms persist beyond 2 weeks, if you experience severe side effects, or if you develop signs of alkalosis such as confusion or muscle twitching. Do not stop prescribed therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine without medical supervision can lead to metabolic alkalosis, electrolyte imbalances, and kidney stones. It may also increase sodium levels, worsening heart failure or hypertension. Regular monitoring of electrolytes and kidney function is advised for prolonged use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Avoiding trigger foods can reduce heartburn episodes.

Evidence: Well-established
Weight loss

Reduces pressure on the stomach and lessens reflux.

Evidence: Well-established
Herbal remedies

Some herbs like ginger may help, but evidence is limited.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Declare it at customs if required. Keep enough supply for your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old man with frequent heartburn after meals
He was prescribed this medicine to take after meals. He noticed relief within 10 minutes of taking it. He also started avoiding spicy foods and lost some weight, which further reduced his symptoms.
💡 Lesson: Taking this medicine as directed and making lifestyle changes can effectively manage heartburn.
👤 A 35-year-old woman with recurrent uric acid kidney stones
Her doctor prescribed this medicine to alkalinize her urine. She took it regularly and her urine pH improved. She also increased her water intake and reduced purine-rich foods. She has not had a stone episode in 2 years.
💡 Lesson: Consistent use of this medicine along with dietary changes can help prevent kidney stones.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: For heartburn, relief is usually felt within a few minutes. For urinary alkalinization, it may take 30 minutes to 1 hour.

Q: Can I take it with other antacids?

A: It is not recommended to take with other antacids without medical advice, as it may cause excessive alkalinization.

Q: Is it safe during pregnancy?

A: Consult your doctor before use. It is generally considered safe for short-term use if prescribed.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for the next dose, skip it. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for bisonate 1000mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken indefinitely for heartburn.
    Fact: Prolonged use without medical supervision can cause electrolyte imbalances and should be avoided.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people with severe kidney disease, heart failure, or metabolic alkalosis.
  • Myth: This medicine can replace prescription medicines for ulcers.
    Fact: It only neutralizes acid and does not treat underlying conditions like ulcers or infections.

🔄 Alternative Options

Generic Alternatives

  • Sodium Bicarbonate 1000 mg tablet

Brand Alternatives

  • Auxisoda-DS Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Auxisoda-DS Tablet","active_ingredient":"Sodium Bicarbonate 1000 mg","uses":"Acid indigestion, urinary alkalinization","onset":"Rapid for heartburn"},{"medicine":"Sodium Bicarbonate 500 mg","active_ingredient":"Sodium Bicarbonate 500 mg","uses":"Milder acid indigestion","onset":"Rapid"},{"medicine":"Potassium Citrate","active_ingredient":"Potassium Citrate","uses":"Urinary alkalinization, kidney stones","onset":"Slower"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory