biogat oral drops - Gatifloxacin (0.3% w/v) medicine

Biogat Oral Drops (Gatifloxacin 0.3% w/v) - Uses, Price, Side Effects

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๐Ÿญ Biomedica International ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is biogat oral drops used for?

Biogat Oral Drops contain Gatifloxacin 0.3% w/v, a fluoroquinolone antibiotic used to treat bacterial infections of the gastrointestinal tract. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, stopping bacterial growth. It is effective against a range of gram-positive and gram-negative bacteria.

  • Generic Name: Gatifloxacin
  • Manufacturer: Biomedica International
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š biogat oral drops Uses & Benefits

Treatment of acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, acute sinusitis, uncomplicated urinary tract infections, and pyelonephritis.

Off-label uses: Bacterial prostatitis, Gonorrhea, Traveler's diarrhea

๐Ÿ“‹ Drug Information

Generic Name(s)Gatifloxacin
Brand NameAbgate
ManufacturerBiomedica International
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassQuinolones/ Fluroquinolones
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; bioavailability approximately 96%.
DistributionWidely distributed into tissues and fluids; high concentrations in lung, sinus, and urinary tract.
Protein BindingApproximately 20% bound to plasma proteins.
MetabolismMinimal hepatic metabolism; primarily excreted unchanged.
Half-Life7-14 hours
ExcretionPrimarily excreted unchanged in urine (70-80%) and feces.
Bioavailability96%
Onset of ActionRapid; within 1-2 hours.
Peak Plasma Time1-2 hours
Duration of ActionApproximately 12-24 hours

How It Works

Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.

Mechanism Steps

1Gatifloxacin enters bacterial cell via porin channels.
2Binds to DNA gyrase (topoisomerase II) and topoisomerase IV.
3Inhibits supercoiling and relaxation of bacterial DNA.

๐Ÿ’ก How to Take biogat oral drops

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of biogat oral drops

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Insomnia

๐Ÿšจ Serious Side Effects

  • Tendon rupture
  • QT prolongation
  • Hypoglycemia
  • Seizures
  • Peripheral neuropathy

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Hepatotoxicity
  • Clostridium difficile colitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Antacids containing magnesium or aluminum Moderate Reduced absorption of Gatifloxacin
NSAIDs Moderate Increased risk of CNS stimulation and seizures
Warfarin Major Increased anticoagulant effect

๐Ÿšจ Major Interactions

  • Class IA antiarrhythmics
  • Class III antiarrhythmics
  • Insulin
  • Oral hypoglycemics

โšก Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Antacids containing magnesium or aluminum
  • Sucralfate
  • Iron supplements
  • Zinc supplements

โ„น๏ธ Minor Interactions

  • Caffeine
  • Theophylline

๐Ÿฝ๏ธ Food Interactions

Avoid dairy products, antacids, and iron supplements within 2-4 hours of dosing.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase risk of CNS effects and hypoglycemia.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to gatifloxacin or any fluoroquinolone; history of tendon disorders; epilepsy; QT prolongation; uncorrected hypokalemia; concurrent use with Class IA or III antiarrhythmics.

๐Ÿ“Š Monitoring Parameters

Renal function, blood glucose, ECG (QT interval), signs of tendonitis or CNS effects.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; avoid use or discontinue breastfeeding.

๐Ÿ’Š Overdose Management

Supportive care; monitor ECG for QT prolongation; no specific antidote; hemodialysis may remove drug.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for biogat oral drops

View All

Alternative brands with exact same active ingredient (Gatifloxacin (0.3% w/v)):

Medical Note: Always consult your doctor before switching medications.

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