amipar eye/ear drops - Amikacin (0.3% w/v) medicine

amipar eye/ear drops

4.4 (8 reviews)
๐Ÿญ Biomedica International ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is amipar eye/ear drops used for?

Amipar Eye/Ear Drops (Amikacin) is used to treat OPHTHAL OTOLOGICALS. It contains Amikacin (0.3% w/v), which Binds to bacterial 30S ribosomal subunit, inhibiting protein synthesis. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Amikacin
  • Manufacturer: Biomedica International
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š amipar eye/ear drops Uses & Benefits

Treatment of bacterial infections of eye (conjunctivitis, keratitis) and ear (otitis externa, otitis media)

Off-label uses: Prophylaxis in ocular surgery (off-label)

๐Ÿ“‹ Drug Information

Generic Name(s)Amikacin
Brand NameAmipar Eye/Ear Drops
ManufacturerBiomedica International
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL OTOLOGICALS
Action ClassAminoglycosides
Route of AdministrationTopical (eye drops, ear drops)
StorageStore at 15-30ยฐC; protect from light; keep tightly closed
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after topical application to eye or ear
DistributionDistributes into extracellular fluid; low penetration into CSF
Protein Binding0-10%
MetabolismNot significantly metabolized
Half-Life2-3 hours (systemic); topical absorption negligible
ExcretionRenally excreted unchanged (systemic); topical application minimal systemic exposure
BioavailabilityNegligible systemic bioavailability after topical use
Onset of ActionRapid (within minutes) for local antibacterial effect
Peak Plasma TimeNot applicable due to minimal systemic absorption
Duration of Action6-8 hours (local effect)

How It Works

Binds to bacterial 30S ribosomal subunit, inhibiting protein synthesis

Mechanism Steps

1Amikacin diffuses through bacterial cell wall
2Binds to 30S ribosomal subunit
3Causes misreading of mRNA codons

๐Ÿ’ก How to Take amipar eye/ear drops

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of amipar eye/ear drops

โœ… Common Side Effects

  • Burning or stinging on application
  • Blurred vision (temporary)
  • Eye irritation

๐Ÿšจ Serious Side Effects

  • Ototoxicity (rare with topical use)
  • Nephrotoxicity (rare with topical use)
  • Hypersensitivity reactions

โš ๏ธ Rare Side Effects

  • Superinfection
  • Contact dermatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Neuromuscular blocking agents Major Enhanced neuromuscular blockade
Other aminoglycosides Major Increased nephrotoxicity and ototoxicity
Potent diuretics (e.g., furosemide) Major Increased ototoxicity
Cisplatin Moderate Increased nephrotoxicity and ototoxicity
Cyclosporine Moderate Increased nephrotoxicity
Vancomycin Moderate Increased nephrotoxicity

๐Ÿšจ Major Interactions

  • Neuromuscular blocking agents
  • Other aminoglycosides
  • Potent diuretics (e.g., furosemide)

โšก Moderate Interactions

  • Cisplatin
  • Cyclosporine
  • Vancomycin

โ„น๏ธ Minor Interactions

  • Penicillins (in vitro antagonism)
  • Cephalosporins

๐Ÿฝ๏ธ Food Interactions

None

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to amikacin or other aminoglycosides; myasthenia gravis (relative)

๐Ÿ“Š Monitoring Parameters

Clinical response; local irritation; hearing if prolonged use

๐Ÿคฑ Lactation Safety

Caution; minimal systemic absorption but avoid if possible

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, supportive care; monitor renal function

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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