Biofast-OZ 200mg/50mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Tendon pain or swelling
- Numbness or tingling in hands or feet
- Seizures
If experiencing severe symptoms, call emergency services immediately.
What is biofast-oz 200mg/50mg tablet used for?
This medicine is a combination antibiotic containing Ofloxacin and Ornidazole, used to treat bacterial and protozoal infections of the gastrointestinal tract. It works by killing the microorganisms causing the infection. It should be taken exactly as prescribed by a doctor.
- Generic Name: Ofloxacin (200mg) + Ornidazole (50mg)
- Manufacturer: Solitaire Pharmacia Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 biofast-oz 200mg/50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ओफ्लोक्सासिन और ओर्निडाजोल का संयोजन है, जिसका उपयोग आंतों के बैक्टीरियल और प्रोटोज़ोअल संक्रमणों के इलाज के लिए किया जाता है। यह अमीबिक पेचिश, जियार्डिया और मिश्रित संक्रमणों में प्रभावी है। यह दवा कीटाणुओं को मारकर संक्रमण को ठीक करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना और मुँह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, टेंडन टूटना, दौरे और त्वचा पर गंभीर प्रतिक्रियाएँ हो सकती हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। दवा लेते समय और आखिरी खुराक के 48 घंटे बाद तक शराब न लें। चक्कर आने पर वाहन न चलाएँ। गुर्दे या जिगर की बीमारी, मिर्गी या टेंडन की समस्या हो तो डॉक्टर को बताएं। धूप से बचें।
💊 biofast-oz 200mg/50mg tablet Uses & Benefits
[{"condition":"Amoebic dysentery","description":"Treatment of intestinal amoebiasis caused by Entamoeba histolytica, relieving diarrhea, abdominal pain, and bloody stools.","evidence":"Well-established"},{"condition":"Giardiasis","description":"Treatment of giardiasis caused by Giardia lamblia, reducing diarrhea, bloating, and malabsorption.","evidence":"Well-established"},{"condition":"Bacterial gastroenteritis","description":"Used for mixed bacterial and protozoal gastrointestinal infections when both aerobic and anaerobic coverage is needed.","evidence":"Moderate"},{"condition":"Intra-abdominal infections","description":"Adjunct in managing intra-abdominal infections like peritonitis and abscesses caused by susceptible organisms.","evidence":"Moderate"},{"condition":"Pelvic inflammatory disease","description":"Part of combination therapy for pelvic inflammatory disease when anaerobic and protozoal coverage is required.","evidence":"Limited"}]
Off-label uses: [{"condition":"Bacterial vaginosis","description":"Sometimes used off-label for bacterial vaginosis when mixed anaerobic and protozoal infections are suspected.","evidence":"Limited"},{"condition":"Dental infections","description":"Occasionally prescribed off-label for dental abscesses when anaerobic coverage is needed, but not first-line.","evidence":"Limited"}]
Primary treatment for: Amoebic dysentery
Also treats: Giardiasis, Bacterial gastroenteritis, Intra-abdominal infections, Pelvic inflammatory disease
📋 Drug Information
| Generic Name(s) | Ofloxacin (200mg) + Ornidazole (50mg) |
| Brand Name | biofast-oz 200mg/50mg tablet |
| Manufacturer | Solitaire Pharmacia Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antimicrobial agents with distinct mechanisms. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Ornidazole, a nitroimidazole, enters susceptible anaerobic bacteria and protozoa where its nitro group is reduced to reactive intermediates that damage DNA, causing strand breakage and cell death. The combination provides broad coverage against aerobic gram-negative bacteria and anaerobic bacteria/protozoa.
Mechanism Steps
💡 How to Take biofast-oz 200mg/50mg tablet
Strength: Tablet containing Ofloxacin 200 mg and Ornidazole 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once or twice daily, depending on the type and severity of infection. The exact dose and duration must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Use with caution due to increased risk of tendon rupture and CNS effects. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For creatinine clearance less than 50 mL/min, the dose of Ofloxacin should be reduced. Consult a clinician for specific dosing. |
| Hepatic Impairment | No specific dose adjustment is established for mild to moderate hepatic impairment. Use with caution in severe hepatic impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose is not established from available information. Follow the prescribed dose strictly. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of biofast-oz 200mg/50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Antacids | Major | |
| Theophylline | Major | |
| NSAIDs | Major | |
| Corticosteroids | Moderate | |
| Oral hypoglycemics | Moderate | |
| Phenytoin | Moderate | |
| Caffeine | Minor | |
| Sucralfate | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Warfarin
- Antacids containing aluminum or magnesium
- Theophylline
- NSAIDs
⚡ Moderate Interactions
- Corticosteroids
- Oral hypoglycemics
- Phenytoin
🍷 Alcohol Interaction
Avoid alcohol completely while taking this medicine and for at least 48 hours after the last dose. Ornidazole can cause a disulfiram-like reaction with symptoms such as severe nausea, vomiting, flushing, headache, and rapid heartbeat.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Ofloxacin, Ornidazole, or any other quinolone or nitroimidazole","History of tendon disorders related to fluoroquinolone use","Myasthenia gravis","Epilepsy or seizure disorders (relative)","Severe renal impairment (dose adjustment needed)","Pregnancy and breastfeeding (unless clearly needed)","Children under 18 years (fluoroquinolones generally avoided)"]
⚠️ Warnings & Precautions
["Fluoroquinolones, including Ofloxacin, can cause tendonitis and tendon rupture, especially in older adults, those with kidney disease, or on corticosteroids. Stop if tendon pain occurs.","May cause peripheral neuropathy; discontinue if symptoms develop.","Can exacerbate myasthenia gravis; avoid in such patients.","May cause seizures; caution in patients with CNS disorders.","Avoid excessive sun exposure due to photosensitivity risk.","Ornidazole may cause disulfiram-like reaction with alcohol; avoid alcohol.","May affect blood sugar; monitor in diabetics.","Not recommended for children under 18 years due to risk of cartilage damage.","Use with caution in elderly and renally impaired patients; dose adjustment may be needed."]
🤱 Lactation Safety
Ofloxacin and Ornidazole are excreted in breast milk. Breastfeeding is not recommended while taking this medicine. Consult your doctor for alternative feeding options.
💊 Overdose Management
Overdose may cause nausea, vomiting, dizziness, and seizures. There is no specific antidote. Treatment is supportive and symptomatic. Maintain hydration and monitor vital signs. In case of overdose, contact a poison control center or emergency department immediately.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, as this can lead to resistance. Take the tablet with a full glass of water, with or without food. Avoid alcohol completely during treatment and for at least 48 hours after the last dose, as it can cause a disulfiram-like reaction with Ornidazole. Do not drive or operate heavy machinery if you feel dizzy. Inform your doctor if you have kidney or liver problems, epilepsy, or a history of tendon problems. Avoid excessive sunlight as Ofloxacin can make your skin more sensitive to UV rays. Complete the full course as prescribed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, kidney impairment, and CNS effects. Dose adjustment may be needed based on renal function. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy unless clearly needed. Consult your doctor for alternative treatments if you are pregnant or planning to conceive.
🏥 Post-Surgery Considerations
This medicine may be used to treat or prevent infections after surgery. Follow your surgeon's instructions regarding dosing and duration. Inform your surgeon if you are taking this medicine before any surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with other medications used during dental work. Maintain good oral hygiene to prevent infections.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while you are recovering from an infection. If you experience tendon pain or swelling, stop exercising and consult your doctor immediately.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. Take sick leave if you have severe diarrhea or fever to prevent spreading infection to others.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Complete the full prescribed course. If you experience serious side effects like tendon pain, severe allergic reaction, or seizures, stop immediately and seek medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of bacterial resistance, tendon problems, peripheral neuropathy, and liver or kidney issues. It is not intended for prolonged use unless prescribed by a doctor for a specific chronic infection. Regular monitoring of liver and kidney function may be required.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Essential for managing dehydration from diarrhea, can complement medicine.
Evidence: Well-establishedMay help restore gut flora after antibiotic treatment.
Evidence: ModerateAvoiding certain foods can help reduce symptoms during recovery.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions known with this medicine. However, antibiotics may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Consult your doctor for timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule in consultation with your doctor. Declare it at customs if required. Avoid alcohol during travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.
A: Yes, taking it with food can reduce stomach upset. However, avoid dairy products within 2 hours of the dose.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: No, alcohol must be strictly avoided during treatment and for at least 48 hours after the last dose, as it can cause a severe reaction.
A: No, you must complete the full prescribed course to prevent recurrence and resistance, even if symptoms improve.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of diarrhea.
Fact: This medicine is only effective against specific bacterial and protozoal infections. It does not work for viral diarrhea or other causes. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full prescribed course to prevent recurrence and resistance, even if symptoms improve. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol must be strictly avoided as it can cause a severe disulfiram-like reaction with Ornidazole.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin + Ornidazole tablet
Brand Alternatives
- O2 Tablet
- Oflox OZ Tablet
- Zanocin OZ Tablet
- Normet OZ Tablet